Ronald B. DeMattos

12.9k total citations · 4 hit papers
71 papers, 9.4k citations indexed

About

Ronald B. DeMattos is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Ronald B. DeMattos has authored 71 papers receiving a total of 9.4k indexed citations (citations by other indexed papers that have themselves been cited), including 54 papers in Physiology, 35 papers in Molecular Biology and 11 papers in Pharmacology. Recurrent topics in Ronald B. DeMattos's work include Alzheimer's disease research and treatments (54 papers), Computational Drug Discovery Methods (11 papers) and Cholinesterase and Neurodegenerative Diseases (11 papers). Ronald B. DeMattos is often cited by papers focused on Alzheimer's disease research and treatments (54 papers), Computational Drug Discovery Methods (11 papers) and Cholinesterase and Neurodegenerative Diseases (11 papers). Ronald B. DeMattos collaborates with scholars based in United States, United Kingdom and Japan. Ronald B. DeMattos's co-authors include David M. Holtzman, Steven M. Paul, Kelly R. Bales, David J. Cummins, Jean‐Cosme Dodart, Maia Parsadanian, Mark Odell, John R. Cirrito, Patrick C. May and Jennie Taylor and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Ronald B. DeMattos

71 papers receiving 9.2k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

2001 1.1k citations Ronald B. DeMattos, Kelly R. Bales et al. profile →
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

2011 887 citations Joseph M. Castellano, Jungsu Kim et al. Science Translational Medicine profile →
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

2002 705 citations Jean‐Cosme Dodart, Kelly R. Bales et al. Nature Neuroscience profile →
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

2016 571 citations Yaming Wang, Tyler K. Ulland et al. The Journal of Experimental Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ronald B. DeMattos United States	39	6.8k	3.1k	2.4k	1.7k	1.4k	71	9.4k
Mary Jo LaDu United States	51	7.1k 1.0×	3.8k 1.2×	1.9k 0.8×	1.3k 0.8×	962 0.7×	105	9.6k
Christopher B. Eckman United States	50	9.3k 1.4×	5.9k 1.9×	1.5k 0.6×	2.4k 1.4×	1.6k 1.1×	78	12.6k
Marc Mercken Belgium	44	7.9k 1.2×	4.3k 1.4×	1.6k 0.7×	1.9k 1.1×	1.3k 0.9×	102	10.8k
G. William Rebeck United States	62	6.8k 1.0×	4.4k 1.4×	1.8k 0.8×	926 0.5×	607 0.4×	138	11.2k
Mikio Shoji Japan	55	7.0k 1.0×	5.5k 1.8×	1.8k 0.8×	1.4k 0.8×	820 0.6×	293	12.0k
Linda H. Younkin United States	44	9.2k 1.4×	4.6k 1.5×	2.5k 1.1×	2.1k 1.2×	1.3k 1.0×	72	12.1k
Pritam Das United States	41	4.7k 0.7×	2.4k 0.8×	2.3k 1.0×	1.3k 0.8×	944 0.7×	80	7.5k
Ganesh M. Shankar United States	28	8.1k 1.2×	3.9k 1.3×	1.8k 0.8×	2.2k 1.3×	1.3k 0.9×	87	11.2k
Paul M. Mathews United States	53	7.5k 1.1×	4.5k 1.4×	2.4k 1.0×	1.5k 0.9×	863 0.6×	106	11.3k
Jochen Walter Germany	60	6.0k 0.9×	5.3k 1.7×	2.3k 1.0×	1.5k 0.9×	740 0.5×	148	11.6k

Countries citing papers authored by Ronald B. DeMattos

Since Specialization

Citations

This map shows the geographic impact of Ronald B. DeMattos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ronald B. DeMattos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ronald B. DeMattos more than expected).

Fields of papers citing papers by Ronald B. DeMattos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ronald B. DeMattos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ronald B. DeMattos. The network helps show where Ronald B. DeMattos may publish in the future.

Co-authorship network of co-authors of Ronald B. DeMattos

This figure shows the co-authorship network connecting the top 25 collaborators of Ronald B. DeMattos. A scholar is included among the top collaborators of Ronald B. DeMattos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ronald B. DeMattos. Ronald B. DeMattos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Salloway, Stephen, Kumar Budur, Ronald B. DeMattos, et al.. (2020). Advancing combination therapy for Alzheimer's disease. Alzheimer s & Dementia Translational Research & Clinical Interventions. 6(1). e12073–e12073. 42 indexed citations

Wang, Yaming, Tyler K. Ulland, Jason D. Ulrich, et al.. (2016). TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. The Journal of Experimental Medicine. 213(5). 667–675. 571 indexed citations breakdown →

Hendrix, James A., Randall J. Bateman, H. Robert Brashear, et al.. (2016). Challenges, solutions, and recommendations for Alzheimer's disease combination therapy. Alzheimer s & Dementia. 12(5). 623–630. 38 indexed citations

Portelius, Erik, Robert A. Dean, Ulf Andréasson, et al.. (2014). β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage. Alzheimer s Research & Therapy. 6(5-8). 75–75. 29 indexed citations

DeMattos, Ronald B., Patrick C. May, Margaret M. Racke, et al.. (2014). O1‐10‐03: COMBINATION THERAPY WITH A PLAQUE‐SPECIFIC ABETA ANTIBODY AND BACE INHIBITOR RESULTS IN DRAMATIC PLAQUE LOWERING IN AGED PDAPP TRANSGENIC MICE. Alzheimer s & Dementia. 10(4S_Part_1). 6 indexed citations

Shah, Nilay S., Jean‐Sébastien Vidal, Kamal Masaki, et al.. (2012). Midlife Blood Pressure, Plasma β-Amyloid, and the Risk for Alzheimer Disease. Hypertension. 59(4). 780–786. 171 indexed citations

DeMattos, Ronald B., Jirong Lu, Ying Tang, et al.. (2012). A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice. Neuron. 76(5). 908–920. 276 indexed citations

Castellano, Joseph M., Jungsu Kim, Floy R. Stewart, et al.. (2011). Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance. Science Translational Medicine. 3(89). 89ra57–89ra57. 887 indexed citations breakdown →

Burgess, Braydon L., Margaret M. Racke, Veronica Hirsch‐Reinshagen, et al.. (2008). ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo. Journal of Lipid Research. 49(6). 1254–1267. 52 indexed citations

10.

Tansley, Gavin, Braydon L. Burgess, Su Yuan, et al.. (2007). The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of β-amyloid precursor protein. Journal of Lipid Research. 48(5). 1022–1034. 46 indexed citations

11.

Cao, Guoqing, Kelly R. Bales, Ronald B. DeMattos, & Steven M. Paul. (2007). Liver X Receptor-Mediated Gene Regulation and Cholesterol Homeostasis in Brain: Relevance to Alzheimers Disease Therapeutics. Current Alzheimer Research. 4(2). 179–184. 63 indexed citations

12.

DeMattos, Ronald B., et al.. (2006). P4–246: Passive immunotherapy with M266 results in altered CSF Aβ. Alzheimer s & Dementia. 2(3S_Part_19). 1 indexed citations

13.

Legleiter, Justin, Ronald B. DeMattos, David M. Holtzman, & Tomasz Kowalewski. (2004). In situ AFM studies of astrocyte-secreted apolipoprotein E- and J-containing lipoproteins. Journal of Colloid and Interface Science. 278(1). 96–106. 30 indexed citations

14.

Yu, Liang, Suizhen Lin, Thomas P. Beyer, et al.. (2004). A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes. Journal of Neurochemistry. 88(3). 623–634. 135 indexed citations

15.

Cirrito, John R., Patrick C. May, Mark Odell, et al.. (2003). In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life. Journal of Neuroscience. 23(26). 8844–8853. 321 indexed citations

16.

Dodart, Jean‐Cosme, Kelly R. Bales, Kimberley S. Gannon, et al.. (2002). Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model. Nature Neuroscience. 5(5). 452–457. 705 indexed citations breakdown →

17.

DeMattos, Ronald B., Robert P. Brendza, John E. Heuser, et al.. (2001). Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice. Neurochemistry International. 39(5-6). 415–425. 137 indexed citations

18.

DeMattos, Ronald B., Fayanne E. Thorngate, & David L. Williams. (1999). A Test of the Cytosolic Apolipoprotein E Hypothesis Fails to Detect the Escape of Apolipoprotein E from the Endocytic Pathway into the Cytosol and Shows that Direct Expression of Apolipoprotein E in the Cytosol is Cytotoxic. Journal of Neuroscience. 19(7). 2464–2473. 27 indexed citations

19.

DeMattos, Ronald B., Linda K. Curtiss, & David L. Williams. (1998). A Minimally Lipidated Form of Cell-derived Apolipoprotein E Exhibits Isoform-specific Stimulation of Neurite Outgrowth in the Absence of Exogenous Lipids or Lipoproteins. Journal of Biological Chemistry. 273(7). 4206–4212. 108 indexed citations

20.

Rea, Thomas J., Ronald B. DeMattos, Reynold Homan, Roger S. Newton, & Michael E. Pape. (1996). Lack of correlation between ACAT mRNA expression and cholesterol esterification in primary liver cells. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1299(1). 67–74. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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