Ronald B. DeMattos

12.9k citations

71 papers · 9.4k indexed · 4 hit papers · h-index 39

Physiology top 0.1%
Molecular Biology top 2%
Neurology top 0.2%
Pharmacology top 0.2%
Computational Theory and Mathematics top 0.2%

Co-authors: David M. Holtzman Steven M. Paul Kelly R. Bales David J. Cummins Jean‐Cosme Dodart Maia Parsadanian Mark Odell John R. Cirrito
Topics: Alzheimer's disease research and treatments (54 papers)Computational Drug Discovery Methods (11 papers)Cholinesterase and Neurodegenerative Diseases (11 papers)
Cited by: Neurology Physiology Biological Psychiatry
Journals: Science Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States United Kingdom Belgium

In The Last Decade

Ronald B. DeMattos

71 papers receiving 9.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

2001 1.1k citations Ronald B. DeMattos, Kelly R. Bales et al. profile →
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

2011 887 citations Ronald B. DeMattos, Anne M. Fagan et al. profile →
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model

2002 705 citations Jean‐Cosme Dodart, Kelly R. Bales et al. Nature Neuroscience profile →
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

2016 571 citations Yaming Wang, John A. Tzaferis et al. profile →

Peers

Countries citing papers authored by Ronald B. DeMattos

Since Specialization

Citations

This map shows the geographic impact of Ronald B. DeMattos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ronald B. DeMattos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ronald B. DeMattos more than expected).

Fields of papers citing papers by Ronald B. DeMattos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ronald B. DeMattos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ronald B. DeMattos. The network helps show where Ronald B. DeMattos may publish in the future.

Co-authorship network of co-authors of Ronald B. DeMattos

This figure shows the co-authorship network connecting the top 25 collaborators of Ronald B. DeMattos. A scholar is included among the top collaborators of Ronald B. DeMattos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ronald B. DeMattos. Ronald B. DeMattos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice 2023 ·Molecular Neurodegeneration ·Xavier Taylor,(unknown),(unknown),Herold Oluoch,Justin T. Hole,Ronald B. DeMattos,Yaming Wang,Feng Pan	50
2	Advancing combination therapy for Alzheimer's disease 2020 ·Alzheimer s & Dementia Translational Research & Clinical Interventions ·Stephen Salloway,(unknown),Kumar Budur,(unknown),Ronald B. DeMattos,Philipp von Rosenstiel,Antonio Páez,Rebecca Evans,Christopher J. Weber,James A. Hendrix,Susan Worley,Lisa J. Bain,María C. Carrillo	42
3	β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage 2014 ·Alzheimer s Research & Therapy ·Erik Portelius,Robert A. Dean,Ulf Andréasson,Niklas Mattsson,(unknown),Maria Olsson,Ronald B. DeMattos,Margaret M. Racke,Henrik Zetterberg,Patrick C. May,Kaj Blennow	29
4	A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice 2012 ·Neuron ·Ronald B. DeMattos,Jirong Lu,Ying Tang,Margaret M. Racke,(unknown),John A. Tzaferis,Justin T. Hole,(unknown),Peter McDonnell,Feng Liu,Robert D. Kinley,William H. Jordan,Michael Hutton	276
5	Safety and Changes in Plasma and Cerebrospinal Fluid Amyloid β After a Single Administration of an Amyloid β Monoclonal Antibody in Subjects With Alzheimer Disease 2010 ·Clinical Neuropharmacology ·Eric Siemers,Stuart Friedrich,Robert A. Dean,Celedon Gonzales,Martin R. Farlow,Steven M. Paul,Ronald B. DeMattos	144
6	ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo 2008 ·Journal of Lipid Research ·Braydon L. Burgess,(unknown),Margaret M. Racke,Veronica Hirsch‐Reinshagen,Jianjia Fan,(unknown),Sophie Stukas,Louise Théroux,Jeniffer Chan,James Donkin,Anna Wilkinson,(unknown),Brian R. Christie,Judes Poirier,Dieter Lütjohann,Ronald B. DeMattos,Cheryl L. Wellington	52
7	The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of β-amyloid precursor protein 2007 ·Journal of Lipid Research ·Gavin Tansley,Braydon L. Burgess,(unknown),Su Yuan,Veronica Hirsch‐Reinshagen,(unknown),Jeniffer Chan,Anna Wilkinson,(unknown),Kathryn E. Naus,(unknown),(unknown),Weihong Song,(unknown),Nan Wang,Ronald B. DeMattos,Cheryl L. Wellington	46
8	Liver X Receptor-Mediated Gene Regulation and Cholesterol Homeostasis in Brain: Relevance to Alzheimers Disease Therapeutics 2007 ·Current Alzheimer Research ·Guoqing Cao,Kelly R. Bales,Ronald B. DeMattos,Steven M. Paul	63
9	P4–246: Passive immunotherapy with M266 results in altered CSF Aβ 2006 ·Alzheimer s & Dementia ·Ronald B. DeMattos,Margaret M. Racke,(unknown),Eric Siemers	1
10	New pathways in drug discovery for alzheimer’s disease 2006 ·Current Neurology and Neuroscience Reports ·Eric Siemers,Robert A. Dean,Ronald B. DeMattos,Patrick C. May	10
11	The Low Density Lipoprotein Receptor Regulates the Level of CentralNervous System Human and Murine Apolipoprotein E but Does Not Modify AmyloidPlaque Pathology in PDAPPMice 2005 ·Journal of Biological Chemistry ·John Denis Fryer,Ronald B. DeMattos,Lynn M. McCormick,Mark Odell,Michael Spinner,Kelly R. Bales,Steven M. Paul,Patrick M. Sullivan,Maia Parsadanian,Guojun Bu,David M. Holtzman	111
12	In situ AFM studies of astrocyte-secreted apolipoprotein E- and J-containing lipoproteins 2004 ·Journal of Colloid and Interface Science ·Justin Legleiter,Ronald B. DeMattos,David M. Holtzman,Tomasz Kowalewski	30
13	A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes 2004 ·Journal of Neurochemistry ·Liang Yu,Suizhen Lin,Thomas P. Beyer,Youyan Zhang,Xin Wu,Kelly R. Bales,Ronald B. DeMattos,Patrick C. May,(unknown),Xian‐Cheng Jiang,Patrick I. Eacho,Guoqing Cao,Steven M. Paul	135
14	Apolipoprotein E Dose-Dependent Modulation of β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease 2004 ·Journal of Molecular Neuroscience ·Ronald B. DeMattos	39
15	Effect of Different Anti-Aβ Antibodies on Aβ Fibrillogenesis as Assessed by Atomic Force Microscopy 2003 ·Journal of Molecular Biology ·Justin Legleiter,Dan L. Czilli,Bruce D. Gitter,Ronald B. DeMattos,David M. Holtzman,Tomasz Kowalewski	89
16	Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease modelbreakdown → 2002 ·Nature Neuroscience ·Jean‐Cosme Dodart,Kelly R. Bales,Kimberley S. Gannon,Stephen J. Greene,Ronald B. DeMattos,Chantal Mathis,Cynthia DeLong,Su Wu,Xin Wu,David M. Holtzman,Steven M. Paul	705
17	Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice 2001 ·Neurochemistry International ·Ronald B. DeMattos,Robert P. Brendza,John E. Heuser,Malca Kierson,John R. Cirrito,John Denis Fryer,Patrick M. Sullivan,Anne M. Fagan,Xianlin Han,David M. Holtzman	137
18	Clusterin contributes to caspase-3–independent brain injury following neonatal hypoxia-ischemia 2001 ·Nature Medicine ·Byung Hee Han,Ronald B. DeMattos,Laura L. Dugan,Jeong Sook Kim‐Han,Robert P. Brendza,John Denis Fryer,Malca Kierson,John R. Cirrito,Kevin L. Quick,Judith A.K. Harmony,Bruce J. Aronow,David M. Holtzman	177
19	A Minimally Lipidated Form of Cell-derived Apolipoprotein E Exhibits Isoform-specific Stimulation of Neurite Outgrowth in the Absence of Exogenous Lipids or Lipoproteins 1998 ·Journal of Biological Chemistry ·Ronald B. DeMattos,Linda K. Curtiss,David L. Williams	108
20	Regulation by Adrenocorticotropic Hormone of the in Vivo Expression of Scavenger Receptor Class B Type I (SR-BI), a High Density Lipoprotein Receptor, in Steroidogenic Cells of the Murine Adrenal Gland 1996 ·Journal of Biological Chemistry ·Attilio Rigotti,Elazer R. Edelman,Philip Seifert,Sohah N. Iqbal,Ronald B. DeMattos,Ryan E. Temel,Monty Krieger,David L. Williams	215

About Ronald B. DeMattos

Ronald B. DeMattos is a scholar working on Physiology, Neurology and Biological Psychiatry, having authored 71 papers that have together received 9.4k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (54 papers), Computational Drug Discovery Methods (11 papers) and Cholinesterase and Neurodegenerative Diseases (11 papers). The work is most often cited by research in Neurology (2.4k citations), Physiology (6.8k citations) and Biological Psychiatry (650 citations). Ronald B. DeMattos has collaborated with scholars based in United States, United Kingdom and Belgium. Frequent co-authors include David M. Holtzman, Steven M. Paul, Kelly R. Bales, David J. Cummins, Jean‐Cosme Dodart, Maia Parsadanian, Mark Odell, John R. Cirrito, Patrick C. May and Jennie Taylor. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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