Gregory A. Petsko

38.3k citations

368 papers · 29.2k indexed · 12 hit papers · h-index 86

Impact in

Molecular Biology top 0.05%
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- Biochemical and Molecular Research
Cell Biology top 0.1%
- Hemoglobin structure and function

Papers in

Biochemistry 31
- Amino Acid Enzymes and Metabolism 24
Molecular Biology 216
- Protein Structure and Dynamics 90
- Biochemical and Molecular Research 23

Co-authors: Dagmar Ringe S.K. Burley Martin Karplus Demetrius Tsernoglou Hans Frauenfelder Mark A. Wilson Robert F. Tilton Ann Stock
Journals: Biochemistry (71 papers)Proceedings of the National Academy of Sciences (31 papers)Journal of Molecular Biology (20 papers)Science (12 papers)Protein Engineering Design and Selection (11 papers)
Partner nations: United States United Kingdom Japan

In The Last Decade

Gregory A. Petsko

353 papers receiving 28.4k citations

Hit Papers

12 papers align trajectories log scale

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations 2015 · 388 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2015 The Lancet Neurology
2007 Nature
2004 Proceedings of the National Academy of Sciences
2000 Science
1992 Nature
1990 The EMBO Journal
1988 Advances in protein chemistry
1986 FEBS Letters
1986 Journal of Molecular Biology
1985 Science
1979 Nature
1975 Nature

Peers

Countries citing papers authored by Gregory A. Petsko

Since Specialization

Citations

This map shows the geographic impact of Gregory A. Petsko's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gregory A. Petsko with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gregory A. Petsko more than expected).

Fields of papers citing papers by Gregory A. Petsko

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gregory A. Petsko. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gregory A. Petsko. The network helps show where Gregory A. Petsko may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Gregory A. Petsko, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Gregory A. Petsko Line = papers co-authored together Gregory A. Petsko links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening Nature Communications ·李万进, Karoline Drangsholt, K. Zarankiewicz, Maximilian Stahl, 賢湯澤, Sandra Van der Auwera, Hans J. Grabe, Henry Völzke, Georg Homuth, Samuel A. Myers, Cory M. Hogaboam, Imre Noth, Fernando J. Martínez, Gregory A. Petsko, Laurie H. Glimcher	2024	2
2	Dimerization of the Alzheimer’s disease pathogenic receptor SORLA regulates its association with retromer Proceedings of the National Academy of Sciences ·Jiewoong Lee, Yu Kitago, Elnaz Fazeli, Christian Bjerggaard Vægter, Scott A. Small, Gregory A. Petsko, Olav M. Andersen	2023	15
3	Structural analysis of human CEACAM1 oligomerization Communications Biology ·Amit Gandhi, Zhenyu Sun, Yu‐Hwa Huang, Rosa Carina Soto-Fajardo, Chao Yang, Gregory A. Petsko, Nicole Beauchemin, Richard S. Blumberg	2022	3
4	The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease Cell Reports ·Yasir H. Qureshi, Diego E. Berman, Samuel E. Marsh, Ronald L. Klein, Vivek Patel, Sabrina Simoes, Tianji He, Gregory A. Petsko, Beth Stevens, Scott A. Small	2022	19
5	A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson's disease Parkinsonism & Related Disorders ·Ruilin Li, Yangshin Park, Ebba Lohmann, Anneke J.A. Kievit, Guido J. Breedveld, 上村民子, Isnawati Sri, Rick van Minkelen, Haşmet Hanağası, Agnita J.W. Boon, Wei Wang, Gregory A. Petsko, Quyen Q. Hoang, Murat Emre, Vincenzo Bonifati	2021	20
6	Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium Communications Biology ·Amit Gandhi, Zhenyu Sun, Rosa Carina Soto-Fajardo, Yu‐Hwa Huang, Yasuyuki Kondo, Daniel A. Bonsor, Eric J. Sundberg, Gerhard Wagner, Vijay K. Kuchroo, Gregory A. Petsko, Richard S. Blumberg	2021	12
7	mGreenLantern: a bright monomeric fluorescent protein with rapid expression and cell filling properties for neuronal imaging Proceedings of the National Academy of Sciences ·Benjamin C. Campbell, Elisa M. Nabel, Mitchell H. Murdock, Cristina Lao‐Peregrín, Pantelis Tsoulfas, Murray G. Blackmore, Francis S. Lee, Conor Liston, Hirofumi Morishita, Gregory A. Petsko	2020	93
8	Targeted stabilization of Munc18‐1 function via pharmacological chaperones EMBO Molecular Medicine ·Evan Dabbs, Mizukami Atsushi, 高薰, Edward Helman, Gregory A. Petsko, Manu Sharma, Jacqueline Burré	2020	14
9	AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease PubMed ·Jonathan B. Rosenberg, Michael G. Kaplitt, Bishnu P. De, Alvin Chen, Victória Milhomem Lima, Pham Duc Hung, Maartje Piet, Lingzhi Zhao, Rodolfo J Ricart Arbona, Sébastien Monette, Jonathan P. Dyke, Douglas Ballon, a b, Dolan Sondhi, Gregory A. Petsko, Steven M. Paul, Ronald G. Crystal	2018	123
10	Crystal Structures of Cystathionine β-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time Biochemistry ·Yupeng Tu, Е. М. Овсиюк, Megan Hill, Liu C, Gregory A. Petsko, L. Drogadis, David B. Berkowitz, Dali Liu, Dagmar Ringe	2018	23
11	Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy PMC ·Fares Bassil, Pierre‐Olivier Fernagut, Erwan Bézard, Alain Pruvost, Thierry Lesté-Lasserre, Quyen Q. Hoang, Dagmar Ringe, Gregory A. Petsko, Wassilios G. Meissner	2016	2
12	Crystallographic Cryoenzymology and the Legacy of Tony Fink Current Protein and Peptide Science ·Gregory A. Petsko	2009	2
13	Zinc Coordination Geometry and Ligand Binding Affinity: The Structural and Kinetic Analysis of the Second-Shell Serine 228 Residue and the Methionine 180 Residue of the Aminopeptidase from Vibrio proteolyticus Biochemistry ·Niloufar Ataie, Quyen Q. Hoang, М В Сидорук, Yupeng Tu, Yantian Wang, Gregory A. Petsko, Dagmar Ringe	2008	38
14	The 1.1-Å resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease Proceedings of the National Academy of Sciences ·Mark A. Wilson, Jennifer L. Collins, Yaacov Hod, Dagmar Ringe, Gregory A. Petsko	2003	264
15	2.4 Å Resolution Crystal Structure of the Prototypical Hormone-Processing Protease Kex2 in Complex with an Ala-Lys-Arg Boronic Acid Inhibitor ^, Biochemistry ·Todd Holyoak, Mark A. Wilson, Timothy D. Fenn, Charles A. Kettner, Gregory A. Petsko, Robert S. Fuller, Dagmar Ringe	2003	68
16	Art is long and time is fleeting: the current problems and future prospects for time-resolved enzyme crystallography Philosophical Transactions of the Royal Society of London Series A Physical and Engineering Sciences ·Gregory A. Petsko	1992	7
17	Activity and structure of the active-site mutants R386Y and R386F of Escherichia coli aspartate aminotransferase Biochemistry ·Avis T. Danishefsky, いっこく堂, Gregory A. Petsko, Dagmar Ringe	1991	36
18	Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analog of the intermediate on the reaction pathway Biochemistry ·R. Davenport, Paul A. Bash, Barbara A. Seaton, Martin Karplus, Gregory A. Petsko, Dagmar Ringe	1991	185
19	Proteins at Work: “Stop-Action” Pictures at Subzero Temperatures Advances in protein chemistry ·Pierre Douzou, Gregory A. Petsko	1984	82
20	The iron content of iron superoxide dismutase: determination by anomalous scattering Proceedings of the Royal Society of London. Series B, Biological sciences ·Dagmar Ringe, Gregory A. Petsko, Fumiyuki Yamakura, Koji Suzuki, Daijiro Ohmori	1983	3

About Gregory A. Petsko

Gregory A. Petsko is a scholar working on Biochemistry, Molecular Biology, Materials Chemistry, Cell Biology and Neurology, having authored 368 papers that have together received 29.2k indexed citations. Recurring topics across this work include Enzyme Structure and Function (123 papers), Protein Structure and Dynamics (90 papers), Amino Acid Enzymes and Metabolism (24 papers), Erythrocyte Function and Pathophysiology (23 papers), Biochemical and Molecular Research (23 papers), Hemoglobin structure and function (22 papers), Parkinson's Disease Mechanisms and Treatments (19 papers) and Mass Spectrometry Techniques and Applications (17 papers). The work is most often cited by research in Molecular Biology (19.5k citations), Cell Biology (4.3k citations), Biochemistry (1.5k citations), Materials Chemistry (8.1k citations) and Neurology (2.5k citations). Gregory A. Petsko has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Dagmar Ringe, S.K. Burley, Martin Karplus, Demetrius Tsernoglou, Hans Frauenfelder, Mark A. Wilson, Robert F. Tilton, Ann Stock, Roger S. Goody and E.F. Pai. Their work appears in journals such as Biochemistry, Proceedings of the National Academy of Sciences, Journal of Molecular Biology, Science and Protein Engineering Design and Selection.

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