Alison Goate

121.2k total citations · 11 hit papers
431 papers, 30.4k citations indexed

About

Alison Goate is a scholar working on Physiology, Molecular Biology and Genetics. According to data from OpenAlex, Alison Goate has authored 431 papers receiving a total of 30.4k indexed citations (citations by other indexed papers that have themselves been cited), including 223 papers in Physiology, 207 papers in Molecular Biology and 126 papers in Genetics. Recurrent topics in Alison Goate's work include Alzheimer's disease research and treatments (187 papers), Genetic Associations and Epidemiology (79 papers) and Bioinformatics and Genomic Networks (52 papers). Alison Goate is often cited by papers focused on Alzheimer's disease research and treatments (187 papers), Genetic Associations and Epidemiology (79 papers) and Bioinformatics and Genomic Networks (52 papers). Alison Goate collaborates with scholars based in United States, United Kingdom and Australia. Alison Goate's co-authors include John C. Morris, Celeste M. Karch, David M. Holtzman, Carlos Cruchaga, Anne M. Fagan, Raphael Kopan, Howard J. Edenberg, Tatiana Foroud, Laura J. Bierut and William J. Ray and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Alison Goate

420 papers receiving 29.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

1999 1.7k citations Bart De Strooper, Alison Goate et al. profile →
Alzheimer’s Disease: The Challenge of the Second Century

2011 1.1k citations David M. Holtzman, John C. Morris et al. profile →
Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis

2014 953 citations Celeste M. Karch, Alison Goate profile →
Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

1991 913 citations Marie‐Christine Chartier‐Harlin, Liana Fidani et al. profile →
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

2011 887 citations Jungsu Kim, Bruce W. Patterson et al. profile →
APOE predicts amyloid‐beta but not tau Alzheimer pathology in cognitively normal aging

2009 654 citations John C. Morris, Chengjie Xiong et al. profile →
Clinicopathologic Studies in Cognitively Healthy Aging and Alzheimer Disease

1998 546 citations John C. Morris, Alison Goate et al. profile →
Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk

2017 392 citations Alison Goate et al. Molecular Neurodegeneration profile →
GWAS on family history of Alzheimer’s disease

2018 345 citations Alison Goate et al. profile →
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias

2022 166 citations Alison Goate, David M. Holtzman et al. profile →
The complex genetic architecture of Alzheimer's disease: novel insights and future directions

2023 153 citations Shea J. Andrews, Alan E. Renton et al. profile →

Peers

Countries citing papers authored by Alison Goate

Since Specialization

Citations

This map shows the geographic impact of Alison Goate's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alison Goate with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alison Goate more than expected).

Fields of papers citing papers by Alison Goate

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alison Goate. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alison Goate. The network helps show where Alison Goate may publish in the future.

Co-authorship network of co-authors of Alison Goate

This figure shows the co-authorship network connecting the top 25 collaborators of Alison Goate. A scholar is included among the top collaborators of Alison Goate based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alison Goate. Alison Goate is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Differential associations of APOE and TREM2 variants with glial fibrillary acidic protein and neurofilament light in plasma of UK Biobank participants support distinct disease mechanisms 2025 ·Molecular Psychiatry ·Yun Freudenberg‐Hua, Luca Giliberto, Cristina d’Abramo, Wentian Li, Yilong Ma, Alison Goate, Jeremy Koppel	1
2	Cognitive reserve influences symptom onset and longitudinal decline in Dominantly Inherited Alzheimer's Disease 2024 ·Alzheimer s & Dementia ·Jorge J. Llibre‐Guerra, Ruijin Lu, Alan E. Renton, Brian A. Gordon, Tammie L.S. Benzinger, Andrew J. Aschenbrenner, Jason J. Hassenstab, Chengjie Xiong, Richard J. Perrin, Laura Ibáñez, Alison Goate, Carlos Cruchaga, John C. Morris, Alisha Daniels, Eric McDade, Randall J. Bateman	0
3	Protective effects of mitochondrial genome abundance on Alzheimer’s Disease: a Mendelian randomization study 2023 ·Alzheimer s & Dementia ·(unknown), (unknown), Heather Wilkins, Judy Pa, Russell H. Swerdlow, Alison Goate, Shea J. Andrews	2
4	5. Collaborative Study on the Genetics of Alcoholism: Functional genomics 2023 ·Genes Brain & Behavior ·Isabel Gameiro‐Ros, Dina Popova, (unknown), Zhiping P. Pang, Yunlong Liu, Danielle M. Dick, Kathleen K. Bucholz, Arpana Agrawal, Bernice Porjesz, Alison Goate, Xiaoling Xuei, Chella Kamarajan, (unknown), Jay A. Tischfield, Howard J. Edenberg, Paul A. Slesinger, Ronald P. Hart	3
5	The collaborative study on the genetics of alcoholism: Genetics 2023 ·Genes Brain & Behavior ·Emma C. Johnson, Jessica E. Salvatore, Dongbing Lai, Alison Merikangas, John I. Nürnberger, Jay A. Tischfield, Xiaoling Xuei, Chella Kamarajan, Leah Wetherill, (unknown), John P. Rice, John R. Kramer, Samuel Kuperman, Tatiana Foroud, Paul A. Slesinger, Alison Goate, Bernice Porjesz, Danielle M. Dick, Howard J. Edenberg, Arpana Agrawal	6
6	Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques 2021 ·Molecular Neurodegeneration ·Pranav Preman, Julia TCW, Sara Calafate, An Snellinx, (unknown), Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison Goate, Bart De Strooper, Amaia M. Arranz	44
7	Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population 2021 ·Aging Cell ·Moeen Riaz, Aamira Huq, Joanne Ryan, Suzanne G. Orchard, Jane Tiller, Jessica E. Lockery, Robyn L. Woods, Rory Wolfe, Alan E. Renton, Alison Goate, Robert Sebra, Eric E. Schadt, Amy Brodtmann, Raj C. Shah, Elsdon Storey, Anne M. Murray, John J. McNeil, Paul Lacaze	22
8	Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models 2020 ·Cells ·James A. Gregory, (unknown), (unknown), Catherine Braine, Miguel Cuevas, (unknown), Natalie Barretto, Nadine Schrode, Güney Akbalık, Kristy Kang, Esther Cheng, Kathryn R. Bowles, Steven Lotz, Susan K. Goderie, Celeste M. Karch, Sally Temple, Alison Goate, Kristen Brennand, Hemali Phatnani	4
9	The Genetic Relationship Between Alcohol Consumption and Aspects of Problem Drinking in an Ascertained Sample 2019 ·Alcoholism Clinical and Experimental Research ·Emma C. Johnson, Celine L. St. Pierre, Jacquelyn L. Meyers, Fazil Alıev, Vivia V. McCutcheon, Dongbing Lai, Danielle M. Dick, Alison Goate, John R. Kramer, Samuel Kuperman, John I. Nürnberger, Marc A. Schuckit, Bernice Porjesz, Howard J. Edenberg, Kathleen K. Bucholz, Arpana Agrawal	10
10	An ADH1B variant and peer drinking in progression to adolescent drinking milestones: Evidence of a gene-by-environment interaction 2014 ·eScholarship (California Digital Library) ·Emily Olfson, Howard J. Edenberg, John I. Nürnberger, Arpana Agrawal, Kathleen K. Bucholz, Laura Almasy, David B. Chorlian, Danielle M. Dick, Victor Hesselbrock, John R. Kramer, Samuel Kuperman, Bernice Porjesz, Marc A. Schuckit, Jay A. Tischfield, (unknown), Leah Wetherill, Tatiana Foroud, John P. Rice, Alison Goate, Laura J. Bierut	0
11	Genetic influences on alcohol use across stages of development:GABRA2and longitudinal trajectories of drunkenness from adolescence to young adulthood 2013 ·Addiction Biology ·Danielle M. Dick, Seung Bin Cho, Shawn J. Latendresse, Fazil Alıev, John I. Nürnberger, Howard J. Edenberg, Marc A. Schuckit, Victor Hesselbrock, Bernice Porjesz, Kathleen K. Bucholz, Jen-Chyong Wang, Alison Goate, John R. Kramer, Samuel Kuperman	34
12	Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: The Cache County Dementia Progression Study 2013 ·Alzheimer s & Dementia ·David B. Peterson, (unknown), (unknown), Chris Corcoran, Carlos Cruchaga, Alison Goate, Maria C. Norton, Robert C. Green, Ronald G. Munger, John C.S. Breitner, Kathleen A. Welsh‐Bohmer, Constantine G. Lyketsos, JoAnn T. Tschanz, John Kauwe, (unknown)	28
13	The PSEN1, p.E318G Variant Increases the Risk of Alzheimer's Disease in APOE-ε4 Carriers 2013 ·PLoS Genetics ·Bruno A. Benítez, Celeste M. Karch, Yefei Cai, Sheng Chih Jin, Breanna Cooper, David Carrell, Sarah Bertelsen, Lori B. Chibnik, Julie A. Schneider, David Bennett, (unknown), Anne M. Fagan, David M. Holtzman, John C. Morris, Alison Goate, Carlos Cruchaga	52
14	Interplay of Genetic Risk Factors ( CHRNA5 - CHRNA3 - CHRNB4 ) and Cessation Treatments in Smoking Cessation Success 2012 ·American Journal of Psychiatry ·Li-Shiun Chen, Timothy R. Baker, Megan E. Piper, Naomi Breslau, Dale S. Cannon, Kimberly F. Doheny, Stephanie M. Gogarten, Eric O. Johnson, Nancy L. Saccone, Jen C. Wang, Robert B. Weiss, Alison Goate, (unknown)	97
15	Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS 2012 ·PLoS ONE ·Kristin R. Wildsmith, Jacob M. Basak, Bruce W. Patterson, (unknown), Jungsu Kim, Kevin E. Yarasheski, (unknown), Kwasi G. Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy Sigurdson, Chengjie Xiong, Alison Goate, David M. Holtzman, Randall J. Bateman	4
16	Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease 2011 ·PLoS ONE ·John Kauwe, Carlos Cruchaga, Celeste M. Karch, Brooke Sadler, (unknown), Kevin H. Mayo, (unknown), (unknown), Anne M. Fagan, David M. Holtzman, John C. Morris, Alison Goate, (unknown)	45
17	Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE 2011 ·PLoS Genetics ·Ellen M. Wijsman, Nathan Pankratz, Yoonha Choi, Joseph H. Rothstein, Kelley Faber, Rong Cheng, Joseph H. Lee, Thomas D. Bird, David A. Bennett, Ramon Diaz‐Arrastia, Alison Goate, Martin R. Farlow, Bernardino Ghetti, Robert A. Sweet, Tatiana Foroud, Richard Mayeux, (unknown)	172
18	A New Statistic to Evaluate Imputation Reliability 2010 ·Digital Commons@Becker (Washington University School of Medicine) ·Lin Peng, Sarah M. Hartz, Zhehao Zhang, Scott F. Saccone, Jia Wang, Jay A. Tischfield, Howard J. Edenberg, John R. Kramer, Alison Goate, Laura J. Bierut, John P. Rice	3
19	The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans 2009 ·Cancer Research ·Nancy L. Saccone, Jen C. Wang, Naomi Breslau, Eric O. Johnson, Dorothy K. Hatsukami, Scott F. Saccone, Richard A. Grucza, Lingwei Sun, Weimin Duan, John Budde, Robert Culverhouse, Louis Fox, Anthony L. Hinrichs, Joseph H. Steinbach, Meng–Huang Wu, John P. Rice, Alison Goate, Laura J. Bierut	202
20	SEGREGATION OF A MISSENSE MUTATION IN THE AMYLOID PRECURSOR PROTEIN GENE WITH FAMILIAL ALZHEIMERS-DISEASE 1991 ·UCL Discovery (University College London) ·Alison Goate, Marie‐Christine Chartier‐Harlin, Michael Mullan, Jeffrey A. Brown, Fiona Crawford, Liana Fidani, (unknown), (unknown), N.G. Irving, (unknown), R. Mant, (unknown), Karen Rooke, (unknown), Chris J. Talbot, Anthony J. Griswold, (unknown), (unknown), Martin N. Rossor, (unknown), John Hardy	0

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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