James F. Gusella

73.8k total citations · 13 hit papers
462 papers, 41.2k citations indexed

About

James F. Gusella is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Neurology. According to data from OpenAlex, James F. Gusella has authored 462 papers receiving a total of 41.2k indexed citations (citations by other indexed papers that have themselves been cited), including 297 papers in Molecular Biology, 195 papers in Cellular and Molecular Neuroscience and 134 papers in Neurology. Recurrent topics in James F. Gusella's work include Genetic Neurodegenerative Diseases (163 papers), Mitochondrial Function and Pathology (96 papers) and Neurological disorders and treatments (60 papers). James F. Gusella is often cited by papers focused on Genetic Neurodegenerative Diseases (163 papers), Mitochondrial Function and Pathology (96 papers) and Neurological disorders and treatments (60 papers). James F. Gusella collaborates with scholars based in United States, United Kingdom and Germany. James F. Gusella's co-authors include Marcy E. MacDonald, Rudolph E. Tanzi, Peter St George‐Hyslop, Vijaya Ramesh, Susan A. Slaugenhaupt, Jonathan L. Haines, Richard H. Myers, Andrea I. McClatchey, Marcy E. MacDonald and Rachael L. Neve and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

James F. Gusella

460 papers receiving 40.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 3.0k citations James F. Gusella et al. profile →
The GPR54 Gene as a Regulator of Puberty

2003 1.9k citations Susan A. Slaugenhaupt, James F. Gusella et al. profile →
A polymorphic DNA marker genetically linked to Huntington's disease

1983 1.6k citations James F. Gusella, Rudolph E. Tanzi et al. profile →
Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 1.3k citations Rudolph E. Tanzi, James F. Gusella et al. profile →
Association between Microdeletion and Microduplication at 16p11.2 and Autism

2008 1.1k citations Yiping Shen, Rudolph E. Tanzi et al. profile →
Huntington disease

2015 1.1k citations James F. Gusella et al. profile →
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 913 citations Rudolph E. Tanzi, James F. Gusella et al. profile →
The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein

1997 770 citations Laurie J. Ozelius, Susan Bressman et al. Nature Genetics profile →
Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor.

1995 752 citations Susan A. Slaugenhaupt, James F. Gusella et al. profile →
CAG repeat number governs the development rate of pathology in Huntington's disease

1997 541 citations Jean‐Paul Vonsattel, Marcy E. MacDonald et al. Annals of Neurology profile →
Inactivation of the Mouse Huntington's Disease Gene Homolog Hdh

1995 534 citations Mabel P. Duyao, Jean‐Paul Vonsattel et al. profile →
Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma

1986 421 citations Robert L. Martuza, James F. Gusella et al. profile →
Linkage of a Gene Causing Familial Amyotrophic Lateral Sclerosis to Chromosome 21 and Evidence of Genetic-Locus Heterogeneity

1991 278 citations Jonathan L. Haines, Guy A. Rouleau et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James F. Gusella United States	96	22.3k	14.1k	10.4k	7.3k	7.1k	462	41.2k
Richard D. Palmiter United States	143	30.6k 1.4×	14.2k 1.0×	2.1k 0.2×	13.7k 1.9×	8.6k 1.2×	471	69.2k
Jeffrey Milbrandt United States	106	18.1k 0.8×	12.5k 0.9×	2.1k 0.2×	4.5k 0.6×	3.3k 0.5×	297	34.7k
Luis F. Parada United States	94	17.4k 0.8×	9.4k 0.7×	4.5k 0.4×	4.6k 0.6×	1.8k 0.3×	231	33.7k
Tom Curran United States	111	32.0k 1.4×	14.5k 1.0×	1.8k 0.2×	6.6k 0.9×	3.8k 0.5×	276	50.9k
Michael E. Greenberg United States	125	58.5k 2.6×	26.4k 1.9×	2.5k 0.2×	10.0k 1.4×	8.3k 1.2×	251	88.7k
Peter H. Seeburg Germany	112	34.1k 1.5×	26.1k 1.9×	1.2k 0.1×	6.1k 0.8×	2.9k 0.4×	229	56.1k
David E. Housman United States	104	32.2k 1.4×	7.4k 0.5×	2.7k 0.3×	9.2k 1.3×	2.0k 0.3×	329	47.8k
David A. Greenberg United States	90	11.1k 0.5×	9.0k 0.6×	2.2k 0.2×	5.4k 0.7×	3.5k 0.5×	435	30.5k
Rüdiger Klein Germany	97	17.0k 0.8×	19.9k 1.4×	1.9k 0.2×	2.1k 0.3×	3.1k 0.4×	218	35.0k
Andrew V. Schally United States	103	16.7k 0.7×	9.7k 0.7×	2.3k 0.2×	6.3k 0.9×	3.4k 0.5×	1.6k	54.4k

Countries citing papers authored by James F. Gusella

Since Specialization

Citations

This map shows the geographic impact of James F. Gusella's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James F. Gusella with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James F. Gusella more than expected).

Fields of papers citing papers by James F. Gusella

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James F. Gusella. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James F. Gusella. The network helps show where James F. Gusella may publish in the future.

Co-authorship network of co-authors of James F. Gusella

This figure shows the co-authorship network connecting the top 25 collaborators of James F. Gusella. A scholar is included among the top collaborators of James F. Gusella based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James F. Gusella. James F. Gusella is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Jiang, Andrew, Linya You, Renée R. Handley, et al.. (2024). Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington’s disease model. Human Molecular Genetics. 33(17). 1524–1539. 4 indexed citations

Loupe, Jacob M., Ricardo Mouro Pinto, Kyung‐Hee Kim, et al.. (2020). Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington’s disease knock-in mice is blocked by Mlh1 knock-out. Human Molecular Genetics. 29(18). 3044–3053. 50 indexed citations

Beauchamp, Roberta L., Serkan Erdin, Justin T. Jordan, et al.. (2020). mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition. Journal of Biological Chemistry. 296. 100157–100157. 7 indexed citations

Stamou, Maria, Shi‐Yan Ng, Harrison Brand, et al.. (2019). A Balanced Translocation in Kallmann Syndrome Implicates a Long Noncoding RNA, RMST, as a GnRH Neuronal Regulator. The Journal of Clinical Endocrinology & Metabolism. 105(3). e231–e244. 23 indexed citations

Akgül, Seçkin, Yinghua Li, Siyuan Zheng, et al.. (2018). Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma. Cell Reports. 24(2). 463–478.e5. 20 indexed citations

Seo, Jinsoo, Oleg Kritskiy, L. Ashley Watson, et al.. (2017). Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia. Journal of Neuroscience. 37(41). 9917–9924. 120 indexed citations

Balasubramanian, Ravikumar, Jin‐Ho Choi, Ludmila Francescatto, et al.. (2014). Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency. PMC. 2 indexed citations

James, Marianne F., Roberta L. Beauchamp, Sangyeul Han, et al.. (2012). Regulation of mTOR Complex 2 Signaling in Neurofibromatosis 2–Deficient Target Cell Types. Molecular Cancer Research. 10(5). 649–659. 81 indexed citations

Zeng, Wenqi, Tammy Gillis, Luc Djoussé, et al.. (2006). Genetic analysis of the GRIK2modifier effect in Huntington's disease. BMC Neuroscience. 7(1). 62–62. 16 indexed citations

10.

Cuajungco, Math P., Maire Leyne, James Mull, et al.. (2001). Cloning, Characterization, and Genomic Structure of the Mouse Ikbkap Gene. DNA and Cell Biology. 20(9). 579–586. 23 indexed citations

11.

White, Jacqueline K., Wojtek Auerbach, Mabel P. Duyao, et al.. (1997). Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion. Nature Genetics. 17(4). 404–410. 398 indexed citations

12.

Donaldson, Deirdre, D.R. Rosen, J. O'Regan, et al.. (1992). Two independent dinucleotide repeat polymorphisms at the D21S235 locus (21q22.1). Human Molecular Genetics. 1(8). 651–651. 2 indexed citations

13.

Kwiatkowski, David J., et al.. (1992). Construction of a GT polymorphism map of human 9q. Genomics. 12(2). 229–240. 147 indexed citations

14.

Narod, Steven A., Dilys M. Parry, Jillian S. Parboosingh, et al.. (1992). Neurofibromatosis type 2 appears to be a genetically homogeneous disease.. Europe PMC (PubMed Central). 51(3). 486–96. 41 indexed citations

15.

Haines, Jonathan L., Laurie J. Ozelius, Anil Menon, et al.. (1990). A genetic linkage map of chromosome 17. Genomics. 8(1). 1–6. 47 indexed citations

16.

Kramer, Patricia L., Deborah de Leon, Laurie J. Ozelius, et al.. (1990). Dystonia gene in Ashkenazi Jewish population is located on chromosome 9q32–34. Annals of Neurology. 27(2). 114–120. 109 indexed citations

17.

Watkins, Paul C., Roger L. Eddy, Anton K. Beck, et al.. (1987). DNA Sequence and Regional Assignment of the Human Follicle-Stimulating Hormone β-Subunit Gene to the Short Arm of Human Chromosome 11. DNA. 6(3). 205–212. 105 indexed citations

18.

Cheng, Shirley V., et al.. (1987). Chromosomal Localization of the Mouse Homolog of the Huntington's Disease Linked G8 ( D4S10 ) Marker. DNA. 6(5). 401–407. 10 indexed citations

19.

Ramesh, Vijaya, et al.. (1986). Investigation of Gyrate Atrophy Using a cDNA Clone for Human Ornithine Aminotransferase. DNA. 5(6). 493–501. 35 indexed citations

20.

Tsiftsoglou, Asterios S., James F. Gusella, Vladimir Volloch, & David E. Housman. (1979). Inhibition by dexamethasone of commitment to erythroid differentiation in murine erythroleukemia cells.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 39(10). 3849–55. 42 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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