Rakez Kayed

35.6k total citations · 10 hit papers
203 papers, 23.8k citations indexed

About

Rakez Kayed is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Rakez Kayed has authored 203 papers receiving a total of 23.8k indexed citations (citations by other indexed papers that have themselves been cited), including 167 papers in Physiology, 91 papers in Molecular Biology and 50 papers in Cellular and Molecular Neuroscience. Recurrent topics in Rakez Kayed's work include Alzheimer's disease research and treatments (164 papers), Neuroinflammation and Neurodegeneration Mechanisms (37 papers) and Prion Diseases and Protein Misfolding (31 papers). Rakez Kayed is often cited by papers focused on Alzheimer's disease research and treatments (164 papers), Neuroinflammation and Neurodegeneration Mechanisms (37 papers) and Prion Diseases and Protein Misfolding (31 papers). Rakez Kayed collaborates with scholars based in United States, Italy and Germany. Rakez Kayed's co-authors include Charles Glabe, Saskia Milton, Urmi Sengupta, Theresa M. McIntire, Cristian A. Lasagna‐Reeves, Elizabeth Head, Carl W. Cotman, Jennifer L. Thompson, Diana L. Castillo‐Carranza and Todd E. Golde and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Rakez Kayed

195 papers receiving 23.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

2003 3.4k citations Rakez Kayed, Charles Glabe et al. profile →
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

2003 3.3k citations Rakez Kayed et al. profile →
Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

2004 1.9k citations Rakez Kayed, Charles Glabe et al. Journal of Biological Chemistry profile →
Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦

2005 852 citations Rakez Kayed, Charles Glabe et al. Journal of Biological Chemistry profile →
Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases

2004 754 citations Rakez Kayed, Charles Glabe et al. Journal of Biological Chemistry profile →
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

2007 631 citations Rakez Kayed, Jessica Wu et al. profile →
The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

2016 584 citations Urmi Sengupta, Rakez Kayed et al. profile →
Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and Distinct

2007 575 citations Rakez Kayed, Charles Glabe et al. Journal of Biological Chemistry profile →
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

2011 467 citations Urmi Sengupta, Rakez Kayed et al. profile →
Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases

2022 182 citations Urmi Sengupta, Rakez Kayed profile →

Peers

Countries citing papers authored by Rakez Kayed

Since Specialization

Citations

This map shows the geographic impact of Rakez Kayed's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rakez Kayed with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rakez Kayed more than expected).

Fields of papers citing papers by Rakez Kayed

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rakez Kayed. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rakez Kayed. The network helps show where Rakez Kayed may publish in the future.

Co-authorship network of co-authors of Rakez Kayed

This figure shows the co-authorship network connecting the top 25 collaborators of Rakez Kayed. A scholar is included among the top collaborators of Rakez Kayed based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rakez Kayed. Rakez Kayed is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A brain‐derived tau oligomer polymorph is associated with cognitive resilience to Alzheimer's disease 2025 ·Alzheimer s & Dementia ·Michela Marcatti, Batbayar Tumurbaatar, (unknown), Pietro Scaduto, Jutatip Guptarak, (unknown), (unknown), Anna Fracassi, Rakez Kayed, Giulio Taglialatela	0
2	iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death 2024 ·Molecular and Cellular Neuroscience ·Panos Theofilas, Chao Wang, David Butler, (unknown), Cathrine Petersen, Andrew J. Ambrose, Brian Chin, Teddy Yang, Shireen Khan, (unknown), Rakez Kayed, Celeste M. Karch, Bruce L. Miller, Jason E. Gestwicki, Li Gan, Sally Temple, Michelle R. Arkin, Lea T. Grinberg	0
3	Nuclear HMGB1 Loss in the Aging Brain Triggers cGAS‐STING Pathway and Neuroinflammation that Contributes to Senescence and Cognitive Decline in Tauopathies 2024 ·Alzheimer s & Dementia ·Sagar Gaikwad, Md. Anzarul Haque, (unknown), (unknown), (unknown), (unknown), Rakez Kayed	0
4	Gut pathobiont enrichment observed in a population predisposed to dementia, type 2 diabetics of Mexican descent living in South Texas 2024 ·SHILAP Revista de lepidopterología ·M Matz, (unknown), Laura Porterfield, (unknown), Michael D. Jochum, Rakez Kayed, Giulio Taglialatela, Randall J. Urban, Shelly A. Buffington	1
5	Generation of nanobodies with conformational specificity for tau oligomers that recognize tau aggregates from human Alzheimer's disease samples 2024 ·Biomaterials Science ·(unknown), (unknown), (unknown), Nemil Bhatt, (unknown), (unknown), Peter M. Tessier, Levi B. Wood, Rakez Kayed, Ravi S. Kane	3
6	Calcineurin inhibition prevents synaptic plasticity deficit induced by brain-derived tau oligomers 2024 ·Brain Communications ·Pietro Scaduto, Michela Marcatti, Nemil Bhatt, Rakez Kayed, Giulio Taglialatela	4
7	Inhibition of Calcineurin with FK506 Reduces Tau Levels and Attenuates Synaptic Impairment Driven by Tau Oligomers in the Hippocampus of Male Mouse Models 2024 ·International Journal of Molecular Sciences ·Michela Marcatti, Batbayar Tumurbaatar, (unknown), Jutatip Guptarak, (unknown), Balaji Krishnan, Rakez Kayed, Anna Fracassi, Giulio Taglialatela	7
8	Aβ/tau oligomer interplay at human synapses supports shifting therapeutic targets for Alzheimer’s disease 2022 ·Cellular and Molecular Life Sciences ·Michela Marcatti, Anna Fracassi, Mauro Montalbano, (unknown), Balaji Krishnan, Rakez Kayed, Giulio Taglialatela	27
9	Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles 2022 ·Biochemistry ·(unknown), Lucas Dillard, (unknown), (unknown), (unknown), Urmi Sengupta, Rakez Kayed, Kenneth A. Taylor, Mario J. Borgnia, Kwang Hun Lim	6
10	Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding 2021 ·Nature Communications ·(unknown), François‐Xavier Cantrelle, (unknown), Filipa S. Carvalho, Joana S. Cristóvão, Urmi Sengupta, Nicha Puangmalai, Ana P. Carapeto, Mário S. Rodrigues, Isabel Cardoso, G. Fritz, Federico Herrera, Rakez Kayed, Isabelle Landrieu, Cláudio M. Gomes	27
11	Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia 2021 ·Cell Reports ·Sagar Gaikwad, Nicha Puangmalai, Alice Bittar, Mauro Montalbano, Stephanie García, Salomé McAllen, Nemil Bhatt, (unknown), Urmi Sengupta, Rakez Kayed	153
12	Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons 2020 ·Brain ·Zhi Ruan, Dhruba Pathak, Srinidhi Venkatesan Kalavai, (unknown), Satoshi Muraoka, Nemil Bhatt, Kayo Takamatsu-Yukawa, Jianqiao Hu, Yuzhi Wang, Samuel Hersh, Maria Ericsson, Santhi Gorantla, Howard E. Gendelman, Rakez Kayed, Seiko Ikezu, Jennifer I. Luebke, Tsuneya Ikezu	187
13	Modulating disease-relevant tau oligomeric strains by small molecules 2020 ·Journal of Biological Chemistry ·Filippa Lo Cascio, Stephanie García, Mauro Montalbano, Nicha Puangmalai, Salomé McAllen, Andrea Pace, Antonio Palumbo Piccionello, Rakez Kayed	40
14	Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer’s disease, progressive supranuclear palsy and dementia with Lewy bodies 2020 ·Cell Death and Disease ·Nicha Puangmalai, Nemil Bhatt, Mauro Montalbano, Urmi Sengupta, Sagar Gaikwad, (unknown), Salomé McAllen, Anna Ellsworth, Stephanie García, Rakez Kayed	75
15	RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction 2020 ·Nature Communications ·Mauro Montalbano, Salomé McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, (unknown), Michael G. Kharas, Rakez Kayed	67
16	Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration 2019 ·Aging Cell ·(unknown), Salomé McAllen, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Anna Ellsworth, Rakez Kayed	31
17	Tau Interacts with the C-Terminal Region of α-Synuclein, Promoting Formation of Toxic Aggregates with Distinct Molecular Conformations 2019 ·Biochemistry ·(unknown), Rakez Kayed, Sungsool Wi, Kwang Hun Lim	63
18	Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons 2012 ·Journal of Biological Chemistry ·Jessica Wu, Mathieu Herman, Li Liu, Sabrina Simoes, Christopher M. Acker, Helen Y. Figueroa, Joshua Steinberg, Martin Margittai, Rakez Kayed, Chiara Zurzolo, Gilbert Di Paolo, Karen Duff	408
19	α‐Synuclein oligomers oppose long‐term potentiation and impair memory through a calcineurin‐dependent mechanism: relevance to human synucleopathic diseases 2011 ·Journal of Neurochemistry ·(unknown), Volker Neugebauer, Kelly T. Dineley, Rakez Kayed, Wenru Zhang, Lindsay C. Reese, Giulio Taglialatela	95
20	Exercise reverses preamyloid oligomer and prolongs survival in αB-crystallin-based desmin-related cardiomyopathy 2007 ·Proceedings of the National Academy of Sciences ·Alina Maloyan, James Gulick, Charles Glabe, Rakez Kayed, Jeffrey Robbins	68

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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