Saskia Milton

9.0k citations

34 papers · 7.5k indexed · 4 hit papers · h-index 21

Physiology top 0.2%
Molecular Biology top 1%
Cellular and Molecular Neuroscience top 2%
Pharmacology top 0.5%
Computational Theory and Mathematics top 0.5%

Co-authors: Charles Glabe Rakez Kayed Theresa M. McIntire Elizabeth Head Carl W. Cotman Jennifer L. Thompson Mihaela Necula Angelo Demuro
Topics: Alzheimer's disease research and treatments (20 papers)Prion Diseases and Protein Misfolding (9 papers)Computational Drug Discovery Methods (7 papers)
Cited by: Physiology Neurology Biomaterials
Journals: Science Journal of the American Chemical Society Journal of Biological Chemistry
Partner nations: United States South Africa Saudi Arabia

In The Last Decade

Saskia Milton

34 papers receiving 7.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

2003 3.4k citations Rakez Kayed, Elizabeth Head et al. profile →
Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦

2005 852 citations Rakez Kayed, Saskia Milton et al. Journal of Biological Chemistry profile →
Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases

2004 754 citations Rakez Kayed, Theresa M. McIntire et al. Journal of Biological Chemistry profile →
Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and Distinct

2007 575 citations Rakez Kayed, Saskia Milton et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by Saskia Milton

Since Specialization

Citations

This map shows the geographic impact of Saskia Milton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Saskia Milton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Saskia Milton more than expected).

Fields of papers citing papers by Saskia Milton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Saskia Milton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Saskia Milton. The network helps show where Saskia Milton may publish in the future.

Co-authorship network of co-authors of Saskia Milton

This figure shows the co-authorship network connecting the top 25 collaborators of Saskia Milton. A scholar is included among the top collaborators of Saskia Milton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Saskia Milton. Saskia Milton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Familial Alzheimer’s Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide 2017 ·Journal of Biological Chemistry ·Asa Hatami,(unknown),Saskia Milton,Charles Glabe	115
2	Structural differences between amyloid beta oligomers 2016 ·Biochemical and Biophysical Research Communications ·Leonid Breydo,Dmitry Kurouski,Suhail Rasool,Saskia Milton,Jessica Wu,Vladimir N. Uversky,Igor K. Lednev,Charles Glabe	61
3	Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques 2014 ·Neurobiology of Disease ·Anna Pensalfini,Ricardo Albay,Suhail Rasool,Jessica Wu,Asa Hatami,Hiromi Arai,(unknown),Saskia Milton,Wayne W. Poon,María M. Corrada,Claudia H. Kawas,Charles Glabe	86
4	Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice 2012 ·Molecular Neurodegeneration ·Suhail Rasool,Ricardo Albay,Hilda Martínez‐Coria,Leonid Breydo,Jessica Wu,Saskia Milton,(unknown),(unknown),Anna Pensalfini,Frank M. LaFerla,Rakez Kayed,Charles Glabe	35
5	Structure of a C-terminal AHNAK peptide in a 1:2:2 complex with S100A10 and an acetylated N-terminal peptide of annexin A2 2012 ·Acta Crystallographica Section D Biological Crystallography ·Gabriel Ozorowski,Saskia Milton,Hartmut Luecke	23
6	The Oncogenic Jaagsiekte Sheep Retrovirus Cytoplasmic Tail Adopts a Unique Conformation on a Phosphocholine Surface 2012 ·Biophysical Journal ·Ali Alhoshani,Naoyoshi Maeda,(unknown),Saskia Milton,Charles Glabe,Hung Fan,Melanie J. Cocco	1
7	Improving the Fmoc Solid Phase Synthesis of the Cyclic Hexapeptide Complement C5a Antagonist, PMX205 2011 ·International Journal of Peptide Research and Therapeutics ·(unknown),Saskia Milton,A. Richard Chamberlin	5
8	Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta 2010 ·Neurobiology of Disease ·Vitaly Vasilevko,Viorela Pop,Hyun Jin Kim,Tommy Saing,Charles Glabe,Saskia Milton,Edward G. Barrett,Carl W. Cotman,David H. Cribbs,Elizabeth Head	14
9	A Two-Year Study with Fibrillar β-Amyloid (Aβ) Immunization in Aged Canines: Effects on Cognitive Function and Brain Aβ 2008 ·Journal of Neuroscience ·Elizabeth Head,Viorela Pop,Vitaly Vasilevko,(unknown),Tommy Saing,Floyd Sarsoza,(unknown),Lori‐Ann Christie,Saskia Milton,Charles Glabe,Edward G. Barrett,David H. Cribbs	77
10	Pore-Forming Proteins Share Structural and Functional Homology with Amyloid Oligomers 2007 ·NeuroMolecular Medicine ·Yuji Yoshiike,Rakez Kayed,Saskia Milton,Akihiko Takashima,Charles Glabe	63
11	Structural and Dynamic Features of Alzheimer's Aβ Peptide in Amyloid Fibrils Studied by Site-directed Spin Labeling 2002 ·Journal of Biological Chemistry ·Marianna Török,Saskia Milton,Rakez Kayed,(unknown),Theresa M. McIntire,Charles Glabe,Ralf Langen	333
12	The Influence of the Carboxyl Terminus of the Alzheimer Aβ Peptide on its Conformation, Aggregation, and Neurotoxic Properties 2002 ·NeuroMolecular Medicine ·Charles Glabe,Brian Soreghan,Christian J. Pike,(unknown),(unknown),Saskia Milton,(unknown)	16
13	A Conformation Change in the Carboxyl Terminus of Alzheimer's Aβ(1–40) Accompanies the Transition from Dimer to Fibril as Revealed by Fluorescence Quenching Analysis 2000 ·Journal of Biological Chemistry ·William Garzon-Rodriguez,(unknown),(unknown),Saskia Milton,David A. Johnson,Anatoly K. Yatsimirsky,Charles Glabe	44
14	Soluble Amyloid Aβ-(1–40) Exists as a Stable Dimer at Low Concentrations 1997 ·Journal of Biological Chemistry ·William Garzon-Rodriguez,(unknown),Saskia Milton,Charles Glabe	180
15	Breaking the Shackles of the Genetic Code: Engineering Retroviral Proteases Through Total Chemical Synthesis 1995 ·Advances in experimental medicine and biology ·Stephen B. H. Kent,Manuel Baca,John H. Elder,Maria Miller,(unknown),Saskia Milton,Jayasimha Rao,Martina Schnölzer	3
16	Conformational analysis and proteolytic processing of synthetic pre-pro-GnRH/GAP protein 1993 ·Journal of Protein Chemistry ·(unknown),Saskia Milton,(unknown),(unknown),Robert B. Harris	3
17	Total solid-phase synthesis and prolactin-inhibiting activity of the gonadotropin-releasing hormone precursor protein and the gonadotropin-releasing hormone associated peptide 1992 ·Biochemistry ·Saskia Milton,Wolf F. Brandt,Martina Schnölzer,(unknown)	4
18	An improved solid‐phase synthesis of a difficult‐sequence peptide using hexafluoro‐2‐propanol 1990 ·International journal of peptide & protein research ·Saskia Milton,Roy C. Milton	35
19	Selective FSH-releasing activity of [D-Trp9]GAP1–13: Comparison with gonadotropin-releasing abilities of analogs of GAP and natural LHRHs 1990 ·Brain Research Bulletin ·Wai Haung Yu,Robert P. Millar,Saskia Milton,R. C. Milton,Samuel M. McCann	20
20	Prediction of difficult sequences in solid-phase peptide synthesis 1990 ·Journal of the American Chemical Society ·Raymond C. de L. Milton,Saskia Milton,Paul A. Adams	93

About Saskia Milton

Saskia Milton is a scholar working on Physiology, Neurology and Computational Theory and Mathematics, having authored 34 papers that have together received 7.5k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (20 papers), Prion Diseases and Protein Misfolding (9 papers) and Computational Drug Discovery Methods (7 papers). The work is most often cited by research in Physiology (5.5k citations), Neurology (699 citations) and Biomaterials (910 citations). Saskia Milton has collaborated with scholars based in United States, South Africa and Saudi Arabia. Frequent co-authors include Charles Glabe, Rakez Kayed, Theresa M. McIntire, Elizabeth Head, Carl W. Cotman, Jennifer L. Thompson, Mihaela Necula, Angelo Demuro, Erene Mina and Ian Parker. Their work appears in journals such as Science, Journal of the American Chemical Society and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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