Seiko Ikezu

3.6k total citations · 1 hit paper
38 papers, 2.5k citations indexed

About

Seiko Ikezu is a scholar working on Molecular Biology, Neurology and Physiology. According to data from OpenAlex, Seiko Ikezu has authored 38 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 19 papers in Neurology and 12 papers in Physiology. Recurrent topics in Seiko Ikezu's work include Neuroinflammation and Neurodegeneration Mechanisms (19 papers), Extracellular vesicles in disease (17 papers) and Alzheimer's disease research and treatments (12 papers). Seiko Ikezu is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (19 papers), Extracellular vesicles in disease (17 papers) and Alzheimer's disease research and treatments (12 papers). Seiko Ikezu collaborates with scholars based in United States, Japan and Germany. Seiko Ikezu's co-authors include Tsuneya Ikezu, Jennifer I. Luebke, Maria Medalla, Hirohide Asai, Oleg Butovsky, Benjamin Wolozin, Satoshi Tsunoda, Sebastian Kügler, Tarik F. Haydar and Satoshi Muraoka and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Neuroscience and SHILAP Revista de lepidopterología.

In The Last Decade

Seiko Ikezu

36 papers receiving 2.5k citations

Hit Papers

Depletion of microglia and inhibition of exosome synthesi... 2015 2026 2018 2022 2015 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Depletion of microglia and inhibition of exosome synthesis halt tau propagation
    2015 1.2k citations Hirohide Asai, Seiko Ikezu et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Seiko Ikezu United States 18 1.4k 1.1k 936 460 343 38 2.5k
Carlo Sala Frigerio United Kingdom 20 1.0k 0.7× 915 0.8× 864 0.9× 452 1.0× 361 1.1× 42 2.3k
Hansruedi Mathys United States 10 1.1k 0.8× 1.0k 0.9× 742 0.8× 139 0.3× 267 0.8× 12 2.1k
Honghua Zheng China 21 650 0.5× 1.1k 1.0× 756 0.8× 149 0.3× 704 2.1× 46 2.2k
Hirohide Asai Japan 14 861 0.6× 691 0.6× 669 0.7× 191 0.4× 180 0.5× 24 1.9k
Zhijun Zhang China 34 1.0k 0.8× 1.5k 1.3× 270 0.3× 339 0.7× 431 1.3× 68 2.9k
Brian P. Hafler United States 13 1.2k 0.9× 798 0.7× 572 0.6× 133 0.3× 384 1.1× 22 2.2k
Ricarda Diem Germany 31 1.0k 0.8× 758 0.7× 475 0.5× 172 0.4× 404 1.2× 80 3.3k
Denise van Rossum Germany 21 1.2k 0.9× 640 0.6× 493 0.5× 396 0.9× 405 1.2× 31 2.7k
Karpagam Srinivasan United States 16 949 0.7× 1.1k 1.0× 733 0.8× 103 0.2× 514 1.5× 16 2.4k
Ludovico Cantuti‐Castelvetri Germany 21 1.1k 0.8× 1.1k 1.0× 792 0.8× 142 0.3× 636 1.9× 27 2.8k

Countries citing papers authored by Seiko Ikezu

Since Specialization
Citations

This map shows the geographic impact of Seiko Ikezu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seiko Ikezu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seiko Ikezu more than expected).

Fields of papers citing papers by Seiko Ikezu

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seiko Ikezu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seiko Ikezu. The network helps show where Seiko Ikezu may publish in the future.

Co-authorship network of co-authors of Seiko Ikezu

This figure shows the co-authorship network connecting the top 25 collaborators of Seiko Ikezu. A scholar is included among the top collaborators of Seiko Ikezu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Seiko Ikezu. Seiko Ikezu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
You, Yang, Zhengrong Zhang, Steyner F. Côrtes, et al.. (2025). Rapid and high-yield recovery of plasma-derived extracellular vesicles using modified chromatography with soluble protein depletion for biomarker discovery. Cell Communication and Signaling. 23(1). 253–253.
2.
Zhang, Zhengrong, Yang You, Nadia Sultana, et al.. (2024). ATP1A3 as a target for isolating neuron‐specific extracellular vesicles from human brain and biofluids. Alzheimer s & Dementia. 20(S2).
3.
Xu, Shihan, et al.. (2024). Comparison of nanoimaging and nanoflow based detection of extracellular vesicles at a single particle resolution. SHILAP Revista de lepidopterología. 3(10). e70016–e70016. 6 indexed citations
4.
Abdullah, M. F. L., Zhi Ruan, Seiko Ikezu, & Tsuneya Ikezu. (2024). P2RX7 plays a critical role in extracellular vesicle‐mediated secretion of pathogenic molecules from microglia and astrocytes. SHILAP Revista de lepidopterología. 3(7). e155–e155. 5 indexed citations
5.
Bodart‐Santos, Victor, et al.. (2024). Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo. Cell Reports. 43(12). 115025–115025. 2 indexed citations
6.
You, Yang, Zhengrong Zhang, Nadia Sultana, et al.. (2023). ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids. Science Advances. 9(37). eadi3647–eadi3647. 42 indexed citations
7.
Takamatsu-Yukawa, Kayo, et al.. (2023). Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice. Acta Neuropathologica Communications. 11(1). 166–166. 2 indexed citations
8.
Zhang, Zhengrong, Kaiwen Yu, Yang You, et al.. (2023). Comprehensive characterization of human brain‐derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications. Journal of Extracellular Vesicles. 12(8). e12358–e12358. 39 indexed citations
9.
Yeh, Hana, Maya E. Woodbury, Kaitlin L. Ingraham Dixie, Tsuneya Ikezu, & Seiko Ikezu. (2022). Microglial WNT5A supports dendritic spines maturation and neuronal firing. Brain Behavior and Immunity. 107. 403–413. 13 indexed citations
10.
Shi, Haoshen, Zhuoran Yin, Yosef Koronyo, et al.. (2022). Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia. Acta Neuropathologica Communications. 10(1). 136–136. 19 indexed citations
11.
Ruan, Zhi, Kayo Takamatsu-Yukawa, Yuzhi Wang, et al.. (2022). Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia. Cell Reports. 39(6). 110791–110791. 10 indexed citations
12.
Delpech, Jean-Christophe, Shawn Herron, Naotoshi Iwahara, et al.. (2021). Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Molecular Neurodegeneration. 16(1). 18–18. 155 indexed citations
13.
Delpech, Jean-Christophe, Shawn Herron, Naotoshi Iwahara, et al.. (2021). Correction to: Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Molecular Neurodegeneration. 16(1). 8 indexed citations
14.
Muraoka, Satoshi, Annina M. DeLeo, Zijian Yang, et al.. (2021). Proteomic Profiling of Extracellular Vesicles Separated from Plasma of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy. Aging and Disease. 12(6). 1363–1363. 17 indexed citations
15.
Ruan, Zhi, Dhruba Pathak, Srinidhi Venkatesan Kalavai, et al.. (2020). Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons. Brain. 144(1). 288–309. 187 indexed citations
16.
Ruan, Zhi, Jean-Christophe Delpech, Srinidhi Venkatesan Kalavai, et al.. (2020). P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice. Molecular Neurodegeneration. 15(1). 47–47. 102 indexed citations
17.
Muraoka, Satoshi, Mark P. Jedrychowski, Harutsugu Tatebe, et al.. (2019). Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy. Frontiers in Neuroscience. 13. 1059–1059. 42 indexed citations
18.
Varnum, Megan, Tomomi Kiyota, Kaitlin L. Ingraham Dixie, Seiko Ikezu, & Tsuneya Ikezu. (2015). The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease. Neurobiology of Aging. 36(11). 2995–3007. 56 indexed citations
19.
Woodbury, Maya E., Robert W. Freilich, Chang Cheng, et al.. (2015). miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction. Journal of Neuroscience. 35(26). 9764–9781. 76 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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