Mark P. Jedrychowski

33.7k total citations · 16 hit papers
93 papers, 22.5k citations indexed

About

Mark P. Jedrychowski is a scholar working on Molecular Biology, Physiology and Cell Biology. According to data from OpenAlex, Mark P. Jedrychowski has authored 93 papers receiving a total of 22.5k indexed citations (citations by other indexed papers that have themselves been cited), including 62 papers in Molecular Biology, 38 papers in Physiology and 25 papers in Cell Biology. Recurrent topics in Mark P. Jedrychowski's work include Adipose Tissue and Metabolism (35 papers), Mitochondrial Function and Pathology (14 papers) and Advanced Proteomics Techniques and Applications (13 papers). Mark P. Jedrychowski is often cited by papers focused on Adipose Tissue and Metabolism (35 papers), Mitochondrial Function and Pathology (14 papers) and Advanced Proteomics Techniques and Applications (13 papers). Mark P. Jedrychowski collaborates with scholars based in United States, Canada and United Kingdom. Mark P. Jedrychowski's co-authors include Steven P. Gygi, Bruce M. Spiegelman, Edward L. Huttlin, Sean A. Beausoleil, Wilhelm Haas, Shingo Kajimura, Jonathan Z. Long, Ramin Rad, Joshua E. Elias and Judit Villén and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Mark P. Jedrychowski

93 papers receiving 22.3k citations

Hit Papers

A PGC1-α-dependent myokine that drives brown-fat-like d... 2004 2026 2011 2018 2012 2004 2013 2010 2004 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
    2012 3.7k citations Mark P. Jedrychowski, James C. Lo et al. profile →
  2. Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
    2004 2.7k citations Anne Brunet, Lora B. Sweeney et al. Science profile →
  3. Identification of a unique TGF-β–dependent molecular and functional signature in microglia
    2013 1.9k citations Mark P. Jedrychowski, Steven P. Gygi et al. profile →
  4. A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression
    2010 1.3k citations Edward L. Huttlin, Mark P. Jedrychowski et al. Cell profile →
  5. Large-scale characterization of HeLa cell nuclear phosphoproteins
    2004 1.2k citations Sean A. Beausoleil, Mark P. Jedrychowski et al. Proceedings of the National Academy of Sciences profile →
  6. MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes
    2014 896 citations Mark P. Jedrychowski, Edward L. Huttlin et al. profile →
  7. Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis
    2014 737 citations Rajesh R. Rao, Jonathan Z. Long et al. Cell profile →
  8. Quantitative Proteomics of the Cancer Cell Line Encyclopedia
    2020 574 citations John Szpyt, Devin K. Schweppe et al. Cell profile →
  9. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat
    2015 571 citations Lawrence Kazak, Edward T. Chouchani et al. Cell profile →
  10. Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
    2014 545 citations Alban Ordureau, Shireen A. Sarraf et al. Molecular Cell profile →
  11. Increasing the Multiplexing Capacity of TMTs Using Reporter Ion Isotopologues with Isobaric Masses
    2012 464 citations Edward L. Huttlin, Mark P. Jedrychowski et al. profile →
  12. Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry
    2015 448 citations Mark P. Jedrychowski, Christiane D. Wrann et al. Cell Metabolism profile →
  13. Plasticity in binding confers selectivity in ligand-induced protein degradation
    2018 427 citations Zhixiang He, Mark P. Jedrychowski et al. Nature Chemical Biology profile →
  14. Accumulation of succinate controls activation of adipose tissue thermogenesis
    2018 376 citations Evanna L. Mills, Mark P. Jedrychowski et al. profile →
  15. Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1
    2016 364 citations Lawrence Kazak, Mark P. Jedrychowski et al. profile →
  16. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging
    2020 260 citations Haopeng Xiao, Mark P. Jedrychowski et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Mark P. Jedrychowski United States 53 11.3k 8.9k 4.6k 2.7k 2.2k 93 22.5k
Bruce E. Kemp Australia 112 31.0k 2.7× 11.1k 1.2× 5.2k 1.1× 4.7k 1.7× 941 0.4× 451 44.8k
Gary W. Cline United States 88 15.2k 1.3× 13.5k 1.5× 7.3k 1.6× 3.0k 1.1× 358 0.2× 215 31.3k
Olga Ilkayeva United States 70 11.0k 1.0× 8.4k 0.9× 3.6k 0.8× 1.7k 0.6× 1.5k 0.7× 208 19.4k
Antonio Vidal‐Puig United Kingdom 86 12.2k 1.1× 12.8k 1.4× 7.4k 1.6× 1.9k 0.7× 413 0.2× 313 26.0k
António Zorzano Spain 78 14.6k 1.3× 5.8k 0.7× 3.0k 0.6× 3.1k 1.1× 343 0.2× 345 23.0k
Morris F. White United States 121 32.8k 2.9× 11.5k 1.3× 6.5k 1.4× 4.8k 1.7× 471 0.2× 346 51.4k
Rosario Rizzuto Italy 103 31.6k 2.8× 6.1k 0.7× 6.2k 1.3× 8.0k 2.9× 489 0.2× 312 42.9k
Peter S. Rabinovitch United States 80 11.9k 1.1× 5.3k 0.6× 2.1k 0.5× 1.5k 0.5× 649 0.3× 305 24.6k
E. Dale Abel United States 90 13.9k 1.2× 7.9k 0.9× 3.4k 0.7× 1.6k 0.6× 824 0.4× 278 28.7k
David E. James Australia 91 19.3k 1.7× 8.6k 1.0× 3.1k 0.7× 7.7k 2.8× 315 0.1× 370 29.3k

Countries citing papers authored by Mark P. Jedrychowski

Since Specialization
Citations

This map shows the geographic impact of Mark P. Jedrychowski's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark P. Jedrychowski with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark P. Jedrychowski more than expected).

Fields of papers citing papers by Mark P. Jedrychowski

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark P. Jedrychowski. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark P. Jedrychowski. The network helps show where Mark P. Jedrychowski may publish in the future.

Co-authorship network of co-authors of Mark P. Jedrychowski

This figure shows the co-authorship network connecting the top 25 collaborators of Mark P. Jedrychowski. A scholar is included among the top collaborators of Mark P. Jedrychowski based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark P. Jedrychowski. Mark P. Jedrychowski is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Liang, Jiaxin, Xixi Zhang, Thomas D. Jackson, et al.. (2025). Selective deficiency of mitochondrial respiratory complex I subunits Ndufs4/6 causes tumor immunogenicity. Nature Cancer. 6(2). 323–337. 3 indexed citations
2.
Liang, Jiaxin, Chi Luo, Christopher F. Bennett, et al.. (2023). Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas. Nature Communications. 14(1). 3251–3251. 15 indexed citations
3.
Møller, Lisbeth L. V., Jonathan R. Davey, Steffen H. Raun, et al.. (2023). The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action. Proceedings of the National Academy of Sciences. 120(27). e2211041120–e2211041120. 5 indexed citations
4.
Shin, Sejeong, Min-Joon Han, Mark P. Jedrychowski, et al.. (2023). mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching. Cell Reports. 42(8). 112868–112868. 16 indexed citations
5.
Yan, Shuai, Manju Kumari, Haopeng Xiao, et al.. (2021). IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis. Journal of Clinical Investigation. 131(7). 56 indexed citations
6.
Bennett, Christopher F., Elizabeth A. Perry, Eduardo Balsa, et al.. (2021). Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly. Nature Chemical Biology. 17(6). 703–710. 32 indexed citations
7.
Yu, Qing, Haopeng Xiao, Mark P. Jedrychowski, et al.. (2020). Sample multiplexing for targeted pathway proteomics in aging mice. Proceedings of the National Academy of Sciences. 117(18). 9723–9732. 78 indexed citations
8.
Prado, Miguel A., Stefanie A.H. de Poot, João A. Paulo, et al.. (2020). Global proteomics of Ubqln2-based murine models of ALS. Journal of Biological Chemistry. 296. 100153–100153. 26 indexed citations
9.
Xiao, Haopeng, Mark P. Jedrychowski, Devin K. Schweppe, et al.. (2020). A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. 180(5). 968–983.e24. 260 indexed citations breakdown →
10.
Kim, Joon T., Mark P. Jedrychowski, Wei Wei, et al.. (2020). A Plasma Protein Network Regulates PM20D1 and N-Acyl Amino Acid Bioactivity. Cell chemical biology. 27(9). 1130–1139.e4. 8 indexed citations
11.
Kazak, Lawrence, Janane F. Rahbani, Bożena Samborska, et al.. (2019). Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity. Nature Metabolism. 1(3). 360–370. 106 indexed citations
12.
Hong, Shangyu, Wei Song, Peter‐James H. Zushin, et al.. (2018). Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes. Molecular Metabolism. 12. 25–38. 56 indexed citations
13.
Soustek, Meghan S., Eduardo Balsa, Mark P. Jedrychowski, et al.. (2018). Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells. Cell Death and Disease. 9(6). 658–658. 20 indexed citations
14.
Tavares, Clint D.J., Kfir Sharabi, John E. Dominy, et al.. (2016). The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator. Journal of Biological Chemistry. 291(20). 10635–10645. 34 indexed citations
15.
Long, Jonathan Z., Katrin J. Svensson, Leslie A. Bateman, et al.. (2016). The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria. Cell. 166(2). 424–435. 191 indexed citations
16.
Jedrychowski, Mark P., Christiane D. Wrann, João A. Paulo, et al.. (2015). Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry. Cell Metabolism. 22(4). 734–740. 448 indexed citations breakdown →
17.
Ordureau, Alban, Shireen A. Sarraf, David M. Duda, et al.. (2014). Quantitative Proteomics Reveal a Feedforward Model for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis. Molecular Cell. 56(3). 462–462. 6 indexed citations
18.
Rao, Rajesh R., Jonathan Z. Long, James P. White, et al.. (2014). Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis. Cell. 157(6). 1279–1291. 737 indexed citations breakdown →
19.
Brunet, Anne, Lora B. Sweeney, James Fitzhugh Sturgill, et al.. (2004). Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase. Science. 303(5666). 2011–2015. 2730 indexed citations breakdown →
20.
Beausoleil, Sean A., Mark P. Jedrychowski, Daniel Schwartz, et al.. (2004). Large-scale characterization of HeLa cell nuclear phosphoproteins. Proceedings of the National Academy of Sciences. 101(33). 12130–12135. 1190 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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