Mark P. Jedrychowski

33.7k citations

93 papers · 22.5k indexed · 16 hit papers · h-index 53

Co-authors: Steven P. Gygi Bruce M. Spiegelman Edward L. Huttlin Sean A. Beausoleil Wilhelm Haas Shingo Kajimura Jonathan Z. Long Ramin Rad
Topics: Adipose Tissue and Metabolism (35 papers)Mitochondrial Function and Pathology (14 papers)Advanced Proteomics Techniques and Applications (13 papers)
Cited by: Geriatrics and Gerontology Aging Physiology
Journals: Nature Science Cell
Partner nations: United States Canada United Kingdom

In The Last Decade

Mark P. Jedrychowski

93 papers receiving 22.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

2012 3.7k citations Mark P. Jedrychowski, James C. Lo et al. profile →
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

2004 2.7k citations Anne Brunet, Lora B. Sweeney et al. Science profile →
Identification of a unique TGF-β–dependent molecular and functional signature in microglia

2013 1.9k citations Mark P. Jedrychowski, Steven P. Gygi et al. profile →
A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

2010 1.3k citations Edward L. Huttlin, Mark P. Jedrychowski et al. Cell profile →
Large-scale characterization of HeLa cell nuclear phosphoproteins

2004 1.2k citations Sean A. Beausoleil, Mark P. Jedrychowski et al. Proceedings of the National Academy of Sciences profile →
MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes

2014 896 citations Mark P. Jedrychowski, Edward L. Huttlin et al. profile →
Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

2014 737 citations Rajesh R. Rao, Jonathan Z. Long et al. Cell profile →
Quantitative Proteomics of the Cancer Cell Line Encyclopedia

2020 574 citations John Szpyt, Devin K. Schweppe et al. Cell profile →
A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

2015 571 citations Lawrence Kazak, Edward T. Chouchani et al. Cell profile →
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis

2014 545 citations Alban Ordureau, Shireen A. Sarraf et al. Molecular Cell profile →
Increasing the Multiplexing Capacity of TMTs Using Reporter Ion Isotopologues with Isobaric Masses

2012 464 citations Edward L. Huttlin, Mark P. Jedrychowski et al. profile →
Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

2015 448 citations Mark P. Jedrychowski, Christiane D. Wrann et al. Cell Metabolism profile →
Plasticity in binding confers selectivity in ligand-induced protein degradation

2018 427 citations Zhixiang He, Mark P. Jedrychowski et al. Nature Chemical Biology profile →
Accumulation of succinate controls activation of adipose tissue thermogenesis

2018 376 citations Evanna L. Mills, Mark P. Jedrychowski et al. profile →
Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

2016 364 citations Lawrence Kazak, Mark P. Jedrychowski et al. profile →
A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

2020 260 citations Haopeng Xiao, Mark P. Jedrychowski et al. Cell profile →

Peers

Countries citing papers authored by Mark P. Jedrychowski

Since Specialization

Citations

This map shows the geographic impact of Mark P. Jedrychowski's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark P. Jedrychowski with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark P. Jedrychowski more than expected).

Fields of papers citing papers by Mark P. Jedrychowski

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark P. Jedrychowski. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark P. Jedrychowski. The network helps show where Mark P. Jedrychowski may publish in the future.

Co-authorship network of co-authors of Mark P. Jedrychowski

This figure shows the co-authorship network connecting the top 25 collaborators of Mark P. Jedrychowski. A scholar is included among the top collaborators of Mark P. Jedrychowski based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark P. Jedrychowski. Mark P. Jedrychowski is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Selective deficiency of mitochondrial respiratory complex I subunits Ndufs4/6 causes tumor immunogenicity 2025 ·Nature Cancer ·Jiaxin Liang,(unknown),Xixi Zhang,Thomas D. Jackson,(unknown),Mark P. Jedrychowski,Steven P. Gygi,Hans R. Widlund,Kai W. Wucherpfennig,Pere Puigserver	3
2	Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas 2023 ·Nature Communications ·Jiaxin Liang,(unknown),Chi Luo,Christopher F. Bennett,Mark P. Jedrychowski,Steve P. Gygi,Hans R. Widlund,Pere Puigserver	15
3	The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action 2023 ·Proceedings of the National Academy of Sciences ·Lisbeth L. V. Møller,(unknown),Jonathan R. Davey,Steffen H. Raun,Nicoline R. Andersen,Jonathan Z. Long,Hongwei Qian,Jacob Jeppesen,Carlos Henríquez‐Olguín,(unknown),Thomas E. Jensen,Kurt Højlund,Jørgen F. P. Wojtaszewski,Joachim Nielsen,Tim Chiu,Mark P. Jedrychowski,Paul Gregorevic,Amira Klip,Erik A. Richter,Lykke Sylow	5
4	mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching 2023 ·Cell Reports ·Sejeong Shin,Min-Joon Han,Mark P. Jedrychowski,Ziyang Zhang,Kevan M. Shokat,David R. Plas,Noah Dephoure,Sang-Oh Yoon	16
5	IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis 2021 ·Journal of Clinical Investigation ·Shuai Yan,Manju Kumari,Haopeng Xiao,Christopher Jacobs,Shihab Kochumon,Mark P. Jedrychowski,Edward T. Chouchani,Rasheed Ahmad,Evan D. Rosen	56
6	Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly 2021 ·Nature Chemical Biology ·Christopher F. Bennett,(unknown),Elizabeth A. Perry,Eduardo Balsa,Pedro Latorre‐Muro,Christopher L. Riley,Chi Luo,Mark P. Jedrychowski,Steven P. Gygi,Pere Puigserver	32
7	Sample multiplexing for targeted pathway proteomics in aging mice 2020 ·Proceedings of the National Academy of Sciences ·Qing Yu,Haopeng Xiao,Mark P. Jedrychowski,Devin K. Schweppe,José Navarrete-Perea,(unknown),John C. Rogers,Edward T. Chouchani,Steven P. Gygi	78
8	Global proteomics of Ubqln2-based murine models of ALS 2020 ·Journal of Biological Chemistry ·(unknown),Miguel A. Prado,Stefanie A.H. de Poot,João A. Paulo,(unknown),Sara L. Domínguez,Martin Weber,Hai Ngu,John Szpyt,Mark P. Jedrychowski,Amy Easton,Steven P. Gygi,Thimo Kurz,Mervyn J. Monteiro,Eric J. Brown,Daniel Finley	26
9	A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Agingbreakdown → 2020 ·Cell ·Haopeng Xiao,Mark P. Jedrychowski,Devin K. Schweppe,Edward L. Huttlin,Qing Yu,David E. Heppner,Jiaming Li,(unknown),Evanna L. Mills,John Szpyt,Zhixiang He,Guangyan Du,Ryan Garrity,Anita Reddy,Laura Pontano Vaites,João A. Paulo,Tinghu Zhang,Nathanael S. Gray,Steven P. Gygi,Edward T. Chouchani	260
10	A Plasma Protein Network Regulates PM20D1 and N-Acyl Amino Acid Bioactivity 2020 ·Cell chemical biology ·Joon T. Kim,Mark P. Jedrychowski,Wei Wei,Daniel Fernández,Curt R. Fischer,Steven M. Banik,Bruce M. Spiegelman,Jonathan Z. Long	8
11	Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity 2019 ·Nature Metabolism ·Lawrence Kazak,Janane F. Rahbani,Bożena Samborska,Gina Z. Lu,Mark P. Jedrychowski,Mathieu Lajoie,Song Zhang,LeeAnn Ramsay,Florence Y. Dou,Danielle Tenen,Edward T. Chouchani,Petras P. Dzeja,Ian R. Watson,Linus Tsai,Evan D. Rosen,Bruce M. Spiegelman	106
12	Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes 2018 ·Molecular Metabolism ·Shangyu Hong,Wei Song,Peter‐James H. Zushin,Bingyang Liu,Mark P. Jedrychowski,Amir I. Mina,Zhaoming Deng,Dimitrije Čabarkapa,Jessica A. Hall,(unknown),Hassan Aliakbarian,John Szpyt,Steven P. Gygi,Ali Tavakkoli,Lydia Lynch,Norbert Perrimon,Alexander S. Banks	56
13	Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells 2018 ·Cell Death and Disease ·Meghan S. Soustek,Eduardo Balsa,(unknown),Mark P. Jedrychowski,Rutger O. Vogel,Jan Smeıtınk,Steve P. Gygi,Pere Puigserver	20
14	The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator 2016 ·Journal of Biological Chemistry ·Clint D.J. Tavares,Kfir Sharabi,John E. Dominy,Yoonjin Lee,Marta Isasa,Jose M. Orozco,Mark P. Jedrychowski,Theodore M. Kamenecka,Patrick R. Griffin,Steven P. Gygi,Pere Puigserver	34
15	The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria 2016 ·Cell ·Jonathan Z. Long,Katrin J. Svensson,Leslie A. Bateman,Hua Lin,Theodore M. Kamenecka,(unknown),(unknown),Rajesh R. Rao,Mi Ra Chang,Mark P. Jedrychowski,João A. Paulo,Steven P. Gygi,Patrick R. Griffin,Daniel K. Nomura,Bruce M. Spiegelman	191
16	Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometrybreakdown → 2015 ·Cell Metabolism ·Mark P. Jedrychowski,Christiane D. Wrann,João A. Paulo,Kaitlyn K. Gerber,John Szpyt,Matthew M. Robinson,K. Sreekumaran Nair,Steven P. Gygi,Bruce M. Spiegelman	448
17	Quantitative Proteomics Reveal a Feedforward Model for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis 2014 ·Molecular Cell ·Alban Ordureau,Shireen A. Sarraf,David M. Duda,Jin‐Mi Heo,Mark P. Jedrychowski,Vladislav O. Sviderskiy,Jennifer L. Olszewski,James T. Koerber,Tiao Xie,Sean A. Beausoleil,James A. Wells,Steven P. Gygi,Brenda A. Schulman,J. Wade Harper	6
18	Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesisbreakdown → 2014 ·Cell ·Rajesh R. Rao,Jonathan Z. Long,James P. White,Katrin J. Svensson,(unknown),(unknown),Mark P. Jedrychowski,Jorge L. Ruas,Christiane D. Wrann,James C. Lo,Donny M. Camera,Jenn Lachey,Steven P. Gygi,Jasbir Seehra,John A. Hawley,Bruce M. Spiegelman	737
19	Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylasebreakdown → 2004 ·Science ·Anne Brunet,Lora B. Sweeney,James Fitzhugh Sturgill,Katrin F. Chua,Paul L. Greer,Yingxi Lin,Hien Tran,Sarah E. Ross,Raúl Mostoslavsky,Haim Cohen,Linda Hu,Hwei-Ling Cheng,Mark P. Jedrychowski,Steven P. Gygi,David Sinclair,Frederick W. Alt,Michael E. Greenberg	2730
20	Large-scale characterization of HeLa cell nuclear phosphoproteinsbreakdown → 2004 ·Proceedings of the National Academy of Sciences ·Sean A. Beausoleil,Mark P. Jedrychowski,Daniel Schwartz,Joshua E. Elias,Judit Villén,Jiaxu Li,Martin A. Cohn,Lewis C. Cantley,Steven P. Gygi	1190

About Mark P. Jedrychowski

Mark P. Jedrychowski is a scholar working on Cell Biology, Physiology and Geriatrics and Gerontology, having authored 93 papers that have together received 22.5k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (35 papers), Mitochondrial Function and Pathology (14 papers) and Advanced Proteomics Techniques and Applications (13 papers). The work is most often cited by research in Geriatrics and Gerontology (2.2k citations), Aging (604 citations) and Physiology (8.9k citations). Mark P. Jedrychowski has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Steven P. Gygi, Bruce M. Spiegelman, Edward L. Huttlin, Sean A. Beausoleil, Wilhelm Haas, Shingo Kajimura, Jonathan Z. Long, Ramin Rad, Joshua E. Elias and Judit Villén. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact