Pere Puigserver

68.6k total citations · 24 hit papers
121 papers, 43.8k citations indexed

About

Pere Puigserver is a scholar working on Molecular Biology, Physiology and Epidemiology. According to data from OpenAlex, Pere Puigserver has authored 121 papers receiving a total of 43.8k indexed citations (citations by other indexed papers that have themselves been cited), including 87 papers in Molecular Biology, 73 papers in Physiology and 22 papers in Epidemiology. Recurrent topics in Pere Puigserver's work include Adipose Tissue and Metabolism (69 papers), Metabolism, Diabetes, and Cancer (30 papers) and Mitochondrial Function and Pathology (23 papers). Pere Puigserver is often cited by papers focused on Adipose Tissue and Metabolism (69 papers), Metabolism, Diabetes, and Cancer (30 papers) and Mitochondrial Function and Pathology (23 papers). Pere Puigserver collaborates with scholars based in United States, Spain and Switzerland. Pere Puigserver's co-authors include Bruce M. Spiegelman, Zhidan Wu, Joseph T. Rodgers, Carles Lerín, Zachary Gerhart‐Hines, Guillaume Adelmant, Vamsi K. Mootha, Steven P. Gygi, Marie Lagouge and Johan Auwerx and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Pere Puigserver

121 papers receiving 43.2k citations

Hit Papers

Mechanisms Controlling Mitochondrial Biogenesis and Respi... 1998 2026 2007 2016 1999 2006 1998 2009 2005 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
    1999 3.4k citations Pere Puigserver, Vamsi K. Mootha et al. profile →
  2. Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
    2006 3.4k citations Pere Puigserver et al. profile →
  3. A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
    1998 3.1k citations Pere Puigserver, Bruce M. Spiegelman et al. profile →
  4. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
    2009 2.6k citations Pere Puigserver et al. profile →
  5. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
    2005 2.6k citations Steven P. Gygi, Bruce M. Spiegelman et al. profile →
  6. Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
    2002 2.1k citations Jiandie D. Lin, Paul T. Tarr et al. profile →
  7. Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator
    2003 1.7k citations Pere Puigserver, Bruce M. Spiegelman profile →
  8. Transcriptional regulation of adipogenesis
    2000 1.7k citations Pere Puigserver, Bruce M. Spiegelman et al. Genes & Development profile →
  9. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
    2001 1.5k citations John C. Yoon, Pere Puigserver et al. profile →
  10. Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
    2003 1.2k citations Pere Puigserver, James Rhee et al. profile →
  11. mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
    2007 1.2k citations Francisca Vázquez, Vamsi K. Mootha et al. profile →
  12. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
    2001 1.2k citations Pere Puigserver, Bruce M. Spiegelman et al. profile →
  13. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α
    2007 1.1k citations Raúl Mostoslavsky, Pere Puigserver et al. The EMBO Journal profile →
  14. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
    2007 863 citations Pere Puigserver et al. The EMBO Journal profile →
  15. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
    2009 808 citations Pere Puigserver et al. profile →
  16. Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1
    2001 620 citations Pere Puigserver, James A. Van Rhee et al. Molecular Cell profile →
  17. Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
    2004 572 citations Vamsi K. Mootha, Christoph Handschin et al. Proceedings of the National Academy of Sciences profile →
  18. PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
    2013 550 citations Francisca Vázquez, Helen Chim et al. profile →
  19. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
    2001 535 citations Pere Puigserver, Bruce M. Spiegelman et al. Proceedings of the National Academy of Sciences profile →
  20. Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction
    2006 522 citations Pere Puigserver et al. Journal of Biological Chemistry profile →
  21. Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
    2017 517 citations Chi Luo, Pere Puigserver et al. profile →
  22. Metabolic adaptations through the PGC‐1α and SIRT1 pathways
    2007 504 citations Pere Puigserver et al. profile →
  23. Insulin regulation of gluconeogenesis
    2017 408 citations Maximilian Hatting, Clint D.J. Tavares et al. profile →
  24. Mechanisms of mitochondrial respiratory adaptation
    2022 162 citations Christopher F. Bennett, Pedro Latorre‐Muro et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Pere Puigserver United States 72 25.8k 22.3k 8.6k 8.3k 4.7k 121 43.8k
Leonard Guarente United States 106 28.9k 1.1× 17.1k 0.8× 10.5k 1.2× 21.8k 2.6× 4.1k 0.9× 205 55.1k
Benoı̂t Viollet France 98 27.2k 1.1× 9.5k 0.4× 10.8k 1.3× 2.3k 0.3× 5.0k 1.1× 344 42.4k
Junichi Sadoshima United States 101 20.9k 0.8× 5.8k 0.3× 8.2k 0.9× 3.3k 0.4× 2.4k 0.5× 372 36.7k
Kristina Schoonjans Switzerland 89 16.6k 0.6× 8.2k 0.4× 6.9k 0.8× 2.8k 0.3× 2.6k 0.6× 203 32.8k
Neil B. Ruderman United States 97 14.1k 0.5× 13.6k 0.6× 6.6k 0.8× 2.4k 0.3× 1.6k 0.3× 248 29.6k
David Carling United Kingdom 85 28.9k 1.1× 11.6k 0.5× 8.2k 1.0× 1.4k 0.2× 3.6k 0.8× 183 40.7k
Reuben J. Shaw United States 53 20.6k 0.8× 5.1k 0.2× 7.6k 0.9× 1.3k 0.2× 5.3k 1.1× 85 30.3k
Laurie J. Goodyear United States 90 20.0k 0.8× 14.8k 0.7× 4.9k 0.6× 1.1k 0.1× 1.8k 0.4× 245 31.8k
Domenico Accili United States 92 18.8k 0.7× 7.8k 0.3× 4.7k 0.5× 1.9k 0.2× 1.9k 0.4× 271 31.5k
Morris J. Birnbaum United States 102 27.6k 1.1× 9.9k 0.4× 5.7k 0.7× 760 0.1× 3.6k 0.8× 243 41.3k

Countries citing papers authored by Pere Puigserver

Since Specialization
Citations

This map shows the geographic impact of Pere Puigserver's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Pere Puigserver with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Pere Puigserver more than expected).

Fields of papers citing papers by Pere Puigserver

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Pere Puigserver. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Pere Puigserver. The network helps show where Pere Puigserver may publish in the future.

Co-authorship network of co-authors of Pere Puigserver

This figure shows the co-authorship network connecting the top 25 collaborators of Pere Puigserver. A scholar is included among the top collaborators of Pere Puigserver based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Pere Puigserver. Pere Puigserver is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Latorre‐Muro, Pedro, Katherine Zhang, Jonathan M. Palozzi, et al.. (2025). Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity. Nature Cell Biology. 27(1). 130–140. 1 indexed citations
2.
Liang, Jiaxin, Xixi Zhang, Thomas D. Jackson, et al.. (2025). Selective deficiency of mitochondrial respiratory complex I subunits Ndufs4/6 causes tumor immunogenicity. Nature Cancer. 6(2). 323–337. 3 indexed citations
3.
Taxin, Zachary, Bo Yuan, Satoshi Oikawa, et al.. (2023). The SLC25A47 locus controls gluconeogenesis and energy expenditure. Proceedings of the National Academy of Sciences. 120(9). e2216810120–e2216810120. 10 indexed citations
4.
Jackson, Thomas D., et al.. (2023). Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival. EMBO Reports. 24(12). e57228–e57228. 6 indexed citations
5.
Liang, Jiaxin, Chi Luo, Christopher F. Bennett, et al.. (2023). Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas. Nature Communications. 14(1). 3251–3251. 15 indexed citations
6.
Latorre‐Muro, Pedro & Pere Puigserver. (2022). Atossa : a royal link between OXPHOS metabolism and macrophage migration. The EMBO Journal. 41(12). e111290–e111290. 1 indexed citations
7.
Bennett, Christopher F., et al.. (2021). Targeting adaptive cellular responses to mitochondrial bioenergetic deficiencies in human disease. FEBS Journal. 289(22). 6969–6993. 5 indexed citations
8.
Lin, Hua, Kfir Sharabi, Lin Li, et al.. (2021). Structure–Activity Relationship and Biological Investigation of SR18292 (16), a Suppressor of Glucagon-Induced Glucose Production. Journal of Medicinal Chemistry. 64(2). 980–990. 4 indexed citations
9.
Bennett, Christopher F., Elizabeth A. Perry, Eduardo Balsa, et al.. (2021). Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly. Nature Chemical Biology. 17(6). 703–710. 32 indexed citations
10.
Luo, Chi, Eduardo Balsa, Elizabeth A. Perry, et al.. (2020). H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP. Journal of Clinical Investigation. 130(2). 853–862. 38 indexed citations
11.
Luo, Chi, Jiaxin Liang, Kfir Sharabi, et al.. (2020). Obesity/Type 2 Diabetes-Associated Liver Tumors Are Sensitive to Cyclin D1 Deficiency. Cancer Research. 80(16). 3215–3221. 16 indexed citations
12.
Tavares, Clint D.J., Kfir Sharabi, John E. Dominy, et al.. (2016). The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator. Journal of Biological Chemistry. 291(20). 10635–10645. 34 indexed citations
13.
Lim, Ji-Hong, Chi Luo, Francisca Vázquez, & Pere Puigserver. (2014). Targeting Mitochondrial Oxidative Metabolism in Melanoma Causes Metabolic Compensation through Glucose and Glutamine Utilization. Cancer Research. 74(13). 3535–3545. 73 indexed citations
14.
Dominy, John E., Yoon‐Jin Lee, Mark P. Jedrychowski, et al.. (2012). The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis. Molecular Cell. 48(6). 900–913. 230 indexed citations
15.
Bhalla, Kavita, Bor Jang Hwang, Ruby E. Dewi, et al.. (2011). PGC1α Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis. Cancer Research. 71(21). 6888–6898. 159 indexed citations
16.
Fan, Melina, James A. Van Rhee, Julie St‐Pierre, et al.. (2004). Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: modulation by p38 MAPK. Genes & Development. 18(3). 278–289. 250 indexed citations
17.
Mootha, Vamsi K., Christoph Handschin, Xiaohui Xie, et al.. (2004). Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proceedings of the National Academy of Sciences. 101(17). 6570–6575. 572 indexed citations breakdown →
18.
Lin, Jiandie D., Paul T. Tarr, Ruojing Yang, et al.. (2003). PGC-1β in the Regulation of Hepatic Glucose and Energy Metabolism. Journal of Biological Chemistry. 278(33). 30843–30848. 206 indexed citations
19.
Yoon, John C., Gang Xu, Jude T. Deeney, et al.. (2003). Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α. Developmental Cell. 5(1). 73–83. 123 indexed citations
20.
García-Palmer, Francisco, Jordi Pericás, Pere Puigserver, et al.. (1997). Diminished response to food deprivation of the rat brown adipose tissue mitochondrial uncoupling system with age. IUBMB Life. 42(6). 1151–1161. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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