Zhixiang He

2.6k total citations · 3 hit papers
21 papers, 1.3k citations indexed

About

Zhixiang He is a scholar working on Molecular Biology, Oncology and Pulmonary and Respiratory Medicine. According to data from OpenAlex, Zhixiang He has authored 21 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 4 papers in Oncology and 3 papers in Pulmonary and Respiratory Medicine. Recurrent topics in Zhixiang He's work include Protein Degradation and Inhibitors (11 papers), Ubiquitin and proteasome pathways (8 papers) and Multiple Myeloma Research and Treatments (2 papers). Zhixiang He is often cited by papers focused on Protein Degradation and Inhibitors (11 papers), Ubiquitin and proteasome pathways (8 papers) and Multiple Myeloma Research and Treatments (2 papers). Zhixiang He collaborates with scholars based in United States, China and France. Zhixiang He's co-authors include Tinghu Zhang, Nathanael S. Gray, Eric S. Fischer, Katherine A. Donovan, Mark P. Jedrychowski, Radosław P. Nowak, Nozhat Safaee, Stephen L. DeAngelo, Mette Ishoey and Joseph D. Mancias and has published in prestigious journals such as Cell, Angewandte Chemie International Edition and Nature Communications.

In The Last Decade

Zhixiang He

20 papers receiving 1.3k citations

Hit Papers

Plasticity in binding confers selectivity in ligand-induc... 2018 2026 2020 2023 2018 2020 2020 100 200 300 400
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Plasticity in binding confers selectivity in ligand-induced protein degradation
    2018 427 citations Radosław P. Nowak, Stephen L. DeAngelo et al. Nature Chemical Biology profile →
  2. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging
    2020 260 citations Haopeng Xiao, Mark P. Jedrychowski et al. Cell profile →
  3. Light-induced control of protein destruction by opto-PROTAC
    2020 226 citations Jing Liu, He Chen et al. Science Advances profile →

Peers

Zhixiang He
Mala Shanmugam United States
Ilaria Laurenzana Italy
Pierosandro Tagliaferri Italy
Lang Ngo United States
Eric B. Springman United States
Lu Min Wong United States
Tetsuro Orita Japan
Martin Schröder Germany
Jake Delmore United States
Jian An China
Mala Shanmugam United States
Zhixiang He
Citations per year, relative to Zhixiang He Zhixiang He (= 1×) peers Mala Shanmugam

Countries citing papers authored by Zhixiang He

Since Specialization
Citations

This map shows the geographic impact of Zhixiang He's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhixiang He with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhixiang He more than expected).

Fields of papers citing papers by Zhixiang He

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhixiang He. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhixiang He. The network helps show where Zhixiang He may publish in the future.

Co-authorship network of co-authors of Zhixiang He

This figure shows the co-authorship network connecting the top 25 collaborators of Zhixiang He. A scholar is included among the top collaborators of Zhixiang He based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhixiang He. Zhixiang He is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gui, Fu, Baishan Jiang, Jie Jiang, et al.. (2025). Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer. Science Advances. 11(17). eadu0847–eadu0847. 2 indexed citations
2.
Huang, Xiongjie, Songlin Xie, Changxiong Liu, et al.. (2025). A novel vascularized hydrogel by encapsulation of lyophilized platelet-rich fibrin into gelatin methacryloyl hydrogel for bone regeneration. Journal of Materials Science Materials in Medicine. 37(1). 5–5.
3.
Liu, Han‐Yuan, Zhixiang He, Inchul You, et al.. (2024). Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Advanced Science. 11(40). e2405829–e2405829. 4 indexed citations
4.
Du, Guangyan, Jie Jiang, Wenchao Lu, et al.. (2024). Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7). European Journal of Medicinal Chemistry. 276. 116613–116613. 1 indexed citations
5.
Liu, Han‐Yuan, Zhengnian Li, Zhixiang He, et al.. (2024). Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism. Nature Communications. 15(1). 5179–5179. 11 indexed citations
6.
Du, Guangyan, Jie Jiang, Nathaniel J. Henning, et al.. (2022). Exploring the target scope of KEAP1 E3 ligase-based PROTACs. Cell chemical biology. 29(10). 1470–1481.e31. 51 indexed citations
7.
Argentini, Manuela, Christelle Michiels, Valérie Forster, et al.. (2021). First identification of ITM2B interactome in the human retina. Scientific Reports. 11(1). 17210–17210. 4 indexed citations
8.
Powell, Chelsea E., Guangyan Du, Jonathan W. Bushman, et al.. (2021). Selective degradation-inducing probes for studying cereblon (CRBN) biology. RSC Medicinal Chemistry. 12(8). 1381–1390. 18 indexed citations
9.
Hu, Airong, et al.. (2021). [Clinicopathological analysis in patients with chronic hepatitis B virus infection in immune tolerant phase].. PubMed. 60(10). 891–897. 2 indexed citations
10.
Liu, Jing, He Chen, Leina Ma, et al.. (2020). Light-induced control of protein destruction by opto-PROTAC. Science Advances. 6(8). eaay5154–eaay5154. 226 indexed citations breakdown →
11.
Xiao, Haopeng, Mark P. Jedrychowski, Devin K. Schweppe, et al.. (2020). A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. 180(5). 968–983.e24. 260 indexed citations breakdown →
12.
Jiang, Jie, Baishan Jiang, Zhixiang He, et al.. (2020). Discovery of Covalent MKK4/7 Dual Inhibitor. Cell chemical biology. 27(12). 1553–1560.e8. 14 indexed citations
13.
Powell, Chelsea E., Guangyan Du, Jianwei Che, et al.. (2020). Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. ACS Chemical Biology. 15(10). 2722–2730. 68 indexed citations
14.
Liu, Yao, Mingfeng Hao, Alan L. Leggett, et al.. (2020). Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13. Journal of Medicinal Chemistry. 63(13). 6708–6726. 36 indexed citations
15.
Teng, Mingxing, Jie Jiang, Zhixiang He, et al.. (2020). Development of CDK2 and CDK5 Dual Degrader TMX‐2172. Angewandte Chemie International Edition. 59(33). 13865–13870. 57 indexed citations
16.
Gui, Fu, Jie Jiang, Zhixiang He, et al.. (2019). A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies. British Journal of Pharmacology. 176(23). 4491–4509. 17 indexed citations
17.
Nowak, Radosław P., Stephen L. DeAngelo, Dennis L. Buckley, et al.. (2018). Plasticity in binding confers selectivity in ligand-induced protein degradation. Nature Chemical Biology. 14(7). 706–714. 427 indexed citations breakdown →
18.
Huang, Wei, Yunzhan Li, Zhixiang He, et al.. (2018). Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities. Journal of Medicinal Chemistry. 61(12). 5424–5434. 38 indexed citations
19.
Wan, Zhenzhou, Yanan Zhang, Zhixiang He, et al.. (2016). A Melting Curve-Based Multiplex RT-qPCR Assay for Simultaneous Detection of Four Human Coronaviruses. International Journal of Molecular Sciences. 17(11). 1880–1880. 57 indexed citations
20.
Zeng, Jiawei, Qianqian Chen, Lili Wang, et al.. (2014). New method for the visual detection of human respiratory syncytial virus using reverse transcription loop-mediated amplification. Journal of Virological Methods. 206. 84–88. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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