Lydia Lynch

8.9k citations

83 papers · 7.1k · 2 hit papers · h-index 42

Impact in

Immunology top 0.5%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- IL-33, ST2, and ILC Pathways
- Immune cells in cancer
Biological Psychiatry top 5%

Papers in

Immunology 53
- Immune Cell Function and Interaction 48
- T-cell and B-cell Immunology 18
- IL-33, ST2, and ILC Pathways 15
- Immune cells in cancer 8
- Immunotherapy and Immune Responses 8
Epidemiology 21
- Adipokines, Inflammation, and Metabolic Diseases 19

Co-authors: Donal O’Shea (17 shared papers)Cliona O’Farrelly (17 shared papers)Andrew E. Hogan (11 shared papers)Jean O’Connell (8 shared papers)Mark A. Exley (6 shared papers)Ayano C. Kohlgruber (6 shared papers)Justin Geoghegan (5 shared papers)Michael B. Brenner (8 shared papers)
Journals: Nature Immunology (6 papers)Nature Metabolism (5 papers)The Journal of Immunology (5 papers)Cell Metabolism (4 papers)Immunity (3 papers)
Partner nations: United States Ireland United Kingdom

In The Last Decade

Lydia Lynch

80 papers receiving 7.0k citations

Lydia Lynch's Hit Papers

align trajectories log scale

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses 2018 · 504 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2018 Nature Immunology
2018 Nature

Peers

Countries citing papers authored by Lydia Lynch

Since Specialization

Citations

This map shows the geographic impact of Lydia Lynch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lydia Lynch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lydia Lynch more than expected).

Fields of papers citing papers by Lydia Lynch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lydia Lynch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lydia Lynch. The network helps show where Lydia Lynch may publish in the future.

Co-authors

The 25 scholars most cited alongside Lydia Lynch, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lydia Lynch Line = papers co-authored together Lydia Lynch links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 83 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Metabolic reprogramming of natural killer cells in obesity limits antitumor responses Nature Immunology ·Xavier Michelet, Lydia Dyck, Andrew E. Hogan, Róisín M. Loftus, Danielle Duquette, Kevin S. Wei, Semir Beyaz, Ali Tavakkoli Hit paper breakdown →	2018	504
2	Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production Immunity ·Lydia Lynch, Michael A. Nowak, Bindu Varghese, Justice Clark, Andrew E. Hogan, Vasillis Toxavidis, Steven P. Balk, Donal O’Shea	2012	422
3	Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer Nature ·Di Wu, Di Hu, Hao Chen, Guo‐Ming Shi, Irfete Sh. Fetahu, Feizhen Wu, Kimberlie Rabidou, Rui Fang Hit paper breakdown →	2018	388
4	Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue Nature Immunology ·Lydia Lynch, Xavier Michelet, Sai Mei Zhang, Patrick J. Brennan, Ashley Moseman, Chantel Lester, Gurdyal Singh Besra, Emilie E. Vomhof‐DeKrey	2014	320
5	Srebp-controlled glucose metabolism is essential for NK cell functional responses Nature Immunology ·Nadine Aßmann, Katie O’Brien, Raymond P. Donnelly, Lydia Dyck, Vanessa Zaiatz-Bittencourt, Róisín M. Loftus, Paul V. Heinrich, Peter Josef Oefner	2017	319
6	Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis Cancer Immunology Research ·Cathal Harmon, Mark W. Robinson, Fiona Hand, Dalal Almuaili, Keno Mentor, Diarmaid D. Houlihan, Emir Hoti, Lydia Lynch	2018	298
7	γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis Nature Immunology ·Ayano C. Kohlgruber, Shani Talia Gal-Oz, Nelson M. LaMarche, Moto Shimazaki, Danielle Duquette, Hui‐Fern Koay, Hung N. Nguyen, Amir I. Mina	2018	263
8	Clinical anxiety, cortisol and interleukin-6: Evidence for specificity in emotion–biology relationships Brain Behavior and Immunity ·Aoife O’Donovan, Brian M. Hughes, George M. Slavich, Lydia Lynch, Marie-Therese Cronin, Cliona O’Farrelly, Kevin M Malone	2010	252
9	Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity European Journal of Immunology ·Lydia Lynch, Donal O’Shea, Des C. Winter, Justin Geoghegan, Derek G. Doherty, Cliona O’Farrelly	2009	220
10	Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus Diabetologia ·Andrew E. Hogan, Gadintshware Gaoatswe, Lydia Lynch, Michelle A. Corrigan, Conor P. Woods, Jean O’Connell, Donal O’Shea	2013	207
11	Are Natural Killer Cells Protecting the Metabolically Healthy Obese Patient? Obesity ·Lydia Lynch, Jean O’Connell, Anna Kwaśnik, Thomas James Cawood, Cliona O’Farrelly, Donal O’Shea	2009	198
12	Interplay between the immune system and adipose tissue in obesity Journal of Endocrinology ·Mark A. Exley, Laura E. Hand, Donal O’Shea, Lydia Lynch	2014	192
13	The Relationship of Omental and Subcutaneous Adipocyte Size to Metabolic Disease in Severe Obesity PLoS ONE ·Jean O’Connell, Lydia Lynch, Tom Cawood, Anna Kwaśnik, Niamh P. Nolan, Justin Geoghegan, Peter Aiden McCormick, Cliona O’Farrelly	2010	174
14	Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity Immunity ·Selma Boulenouar, Xavier Michelet, Danielle Duquette, DAVID PONFERRADA ÁLVAREZ, Andrew E. Hogan, Christina Dold, Donal B O’Connor, Suzanne Stutte	2017	161
15	Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments Nature Immunology ·Noëlla Lopes, Claire McIntyre, Stefania Martin, Mathilde Raverdeau, Nital Sumaria, Ayano C. Kohlgruber, Gina J. Fiala, Leandro Z. Agudelo	2021	161
16	Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis Diabetologia ·Andrew E. Hogan, Anne‐Marie Tobin, Tomás Ahern, M. Corrigan, Gadinthsware Gaoatswe, Ruaidhrí P. Jackson, Vincent P. O’Reilly, Lydia Lynch	2011	155
17	iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy Cell Metabolism ·Lydia Lynch, Andrew E. Hogan, Danielle Duquette, Chantel Lester, Alexander S. Banks, Katherine B. LeClair, David E. Cohen, Abhisek Ghosh	2016	153
18	Altered Distribution and Increased IL-17 Production by Mucosal-Associated Invariant T Cells in Adult and Childhood Obesity The Journal of Immunology ·Eirin Carolan, Laura M. Tobin, Bozgana A. Mangan, Michelle A. Corrigan, Gadinthsware Gaoatswe, Greg Byrne, Justin Geoghegan, Declan Cody	2015	149
19	UCP1 governs liver extracellular succinate and inflammatory pathogenesis Nature Metabolism ·Evanna L. Mills, Cathal Harmon, Mark P. Jedrychowski, Haopeng Xiao, Ryan Garrity, Nhien Tran, Gary Andrew Bradshaw, Accalia Fu	2021	142
20	Natural Killer Cells in Obesity: Impaired Function and Increased Susceptibility to the Effects of Cigarette Smoke PLoS ONE ·Donal O’Shea, Tom Cawood, Cliona O’Farrelly, Lydia Lynch	2010	138

About Lydia Lynch

Lydia Lynch is a scholar working on Immunology, Epidemiology, Physiology, Oncology and Cancer Research, having authored 83 papers that have together received 7.1k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (48 papers), Adipokines, Inflammation, and Metabolic Diseases (19 papers), T-cell and B-cell Immunology (18 papers), IL-33, ST2, and ILC Pathways (15 papers), Adipose Tissue and Metabolism (11 papers), Immune cells in cancer (8 papers), Immunotherapy and Immune Responses (8 papers) and Cancer Immunotherapy and Biomarkers (6 papers). The work is most often cited by research in Immunology (3.2k citations), Biological Psychiatry (135 citations), Epidemiology (1.8k citations), Physiology (1.3k citations) and Cancer Research (619 citations). Lydia Lynch has collaborated with scholars based in United States, Ireland and United Kingdom. Frequent co-authors include Donal O’Shea, Cliona O’Farrelly, Andrew E. Hogan, Jean O’Connell, Mark A. Exley, Ayano C. Kohlgruber, Justin Geoghegan, Michael B. Brenner, Lydia Dyck and Harry Kane. Their work appears in journals such as Nature Immunology, Nature Metabolism, The Journal of Immunology, Cell Metabolism and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Lydia Lynch's Hit Papers

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