Leslie M. Thompson

21.1k total citations · 6 hit papers
128 papers, 12.1k citations indexed

About

Leslie M. Thompson is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Neurology. According to data from OpenAlex, Leslie M. Thompson has authored 128 papers receiving a total of 12.1k indexed citations (citations by other indexed papers that have themselves been cited), including 96 papers in Molecular Biology, 82 papers in Cellular and Molecular Neuroscience and 21 papers in Neurology. Recurrent topics in Leslie M. Thompson's work include Genetic Neurodegenerative Diseases (80 papers), Mitochondrial Function and Pathology (51 papers) and Muscle Physiology and Disorders (23 papers). Leslie M. Thompson is often cited by papers focused on Genetic Neurodegenerative Diseases (80 papers), Mitochondrial Function and Pathology (51 papers) and Muscle Physiology and Disorders (23 papers). Leslie M. Thompson collaborates with scholars based in United States, United Kingdom and Italy. Leslie M. Thompson's co-authors include Aleksey Kazantsev, Joan S. Steffan, Joan Marsh, Yazhen Zhu, David E. Housman, Judit Pallos, John J. Wasmuth, Gillian P. Bates, Rita Shiang and László Bodai and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Leslie M. Thompson

123 papers receiving 11.9k citations

Hit Papers

Mutations in the transmembrane domain of FGFR3 cause the ... 1994 2026 2004 2015 1994 2001 2000 2003 2008 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
    1994 988 citations Leslie M. Thompson, Yazhen Zhu et al. profile →
  2. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
    2001 964 citations Joan S. Steffan, László Bodai et al. profile →
  3. The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
    2000 849 citations Joan S. Steffan, Aleksey Kazantsev et al. Proceedings of the National Academy of Sciences profile →
  4. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
    2003 667 citations Emma Hockly, Victoria M. Richon et al. Proceedings of the National Academy of Sciences profile →
  5. Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
    2008 578 citations Aleksey Kazantsev, Leslie M. Thompson profile →
  6. SUMO Modification of Huntingtin and Huntington's Disease Pathology
    2004 547 citations Joan S. Steffan, Namita Agrawal et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Leslie M. Thompson United States 52 9.1k 5.8k 2.2k 1.8k 1.2k 128 12.1k
Albert R. La Spada United States 52 7.8k 0.9× 5.5k 1.0× 1.3k 0.6× 2.8k 1.6× 1.4k 1.2× 146 11.3k
Tatsushi Toda Japan 49 5.9k 0.6× 2.4k 0.4× 1.1k 0.5× 2.3k 1.3× 1.3k 1.1× 339 9.6k
Elena Cattaneo Italy 66 12.7k 1.4× 9.8k 1.7× 1.4k 0.6× 3.1k 1.7× 2.0k 1.7× 218 19.2k
Bé Wieringa Netherlands 55 9.3k 1.0× 4.9k 0.8× 1.4k 0.6× 1.6k 0.9× 1.1k 0.9× 193 12.6k
Nicole Déglon Switzerland 63 6.8k 0.7× 6.1k 1.1× 2.0k 0.9× 2.3k 1.3× 1.4k 1.2× 162 11.5k
Mathias Bähr Germany 76 9.2k 1.0× 5.9k 1.0× 1.3k 0.6× 2.5k 1.4× 1.7k 1.5× 356 17.3k
Ruth S. Slack Canada 67 8.4k 0.9× 2.5k 0.4× 893 0.4× 1.9k 1.1× 1.7k 1.4× 145 12.6k
Henry L. Paulson United States 73 13.7k 1.5× 10.1k 1.7× 1.9k 0.9× 4.0k 2.2× 1.3k 1.1× 223 17.7k
Azad Bonni United States 57 13.8k 1.5× 3.5k 0.6× 1.9k 0.9× 465 0.3× 1.4k 1.2× 131 19.1k
Olaf Rieß Germany 57 6.1k 0.7× 5.5k 0.9× 1.1k 0.5× 4.2k 2.3× 1.1k 1.0× 262 11.0k

Countries citing papers authored by Leslie M. Thompson

Since Specialization
Citations

This map shows the geographic impact of Leslie M. Thompson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leslie M. Thompson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leslie M. Thompson more than expected).

Fields of papers citing papers by Leslie M. Thompson

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leslie M. Thompson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leslie M. Thompson. The network helps show where Leslie M. Thompson may publish in the future.

Co-authorship network of co-authors of Leslie M. Thompson

This figure shows the co-authorship network connecting the top 25 collaborators of Leslie M. Thompson. A scholar is included among the top collaborators of Leslie M. Thompson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leslie M. Thompson. Leslie M. Thompson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Cui, Ya, Jie Wu, Dan Wang, et al.. (2025). Multi-omic quantitative trait loci link tandem repeat size variation to gene regulation in human brain. Nature Genetics. 57(2). 369–378. 3 indexed citations
2.
Morabito, Samuel, Jennifer Stocksdale, Emily Miyoshi, et al.. (2025). Single-nucleus multi-omics identifies shared and distinct pathways in Pick’s and Alzheimer’s disease. Science Advances. 11(46). eads7973–eads7973.
3.
Sheeler, Carrie, Lisa Duvick, Leslie M. Thompson, et al.. (2024). Expanded ATXN1 alters transcription and calcium signaling in SCA1 human motor neurons differentiated from induced pluripotent stem cells. Neurobiology of Disease. 201. 106673–106673. 2 indexed citations
4.
Kant, Rik van der, Femke M. Feringa, Amanda McQuade, et al.. (2023). Multiomics of iPSC‐derived ApoE3‐ and ApoE4 astrocytes and microglia uncovers cell type specific dysregulation of immunometabolism. Alzheimer s & Dementia. 19(S13).
5.
Thompson, Leslie M. & Harry T. Orr. (2023). HD and SCA1: Tales from two 30-year journeys since gene discovery. Neuron. 111(22). 3517–3530. 10 indexed citations
6.
Morelli, Kathryn H., Qian Wu, Maya L. Gosztyla, et al.. (2022). An RNA-targeting CRISPR–Cas13d system alleviates disease-related phenotypes in Huntington’s disease models. Nature Neuroscience. 26(1). 27–38. 60 indexed citations
7.
Cheng, Yu‐Ting, Lindsay A. Hohsfield, Ricardo Miramontes, et al.. (2021). Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice. Journal of Virology. 96(4). e0196921–e0196921. 17 indexed citations
8.
Nguyen, Thai B., Whitney England, Ryan G. Lim, et al.. (2021). Huntington’s disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization. Journal of Clinical Investigation. 131(12). 39 indexed citations
9.
Conforti, Paola, Dario Besusso, Vittoria Dickinson Bocchi, et al.. (2018). Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes. Proceedings of the National Academy of Sciences. 115(4). E762–E771. 122 indexed citations
10.
Wang, Bo, Li Zeng, Sean Merillat, et al.. (2017). The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin. Neurobiology of Disease. 109(Pt A). 127–136. 22 indexed citations
11.
Sontag, Emily M., Gregor P. Lotz, Namita Agrawal, et al.. (2012). Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models. Journal of Neuroscience. 32(32). 11109–11119. 78 indexed citations
12.
Sleiman, Sama F., Brett Langley, Manuela Basso, et al.. (2011). Mithramycin Is a Gene-Selective Sp1 Inhibitor That Identifies a Biological Intersection between Cancer and Neurodegeneration. Journal of Neuroscience. 31(18). 6858–6870. 111 indexed citations
13.
Luthi‐Carter, Ruth, David Taylor, Judit Pallos, et al.. (2010). SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. Proceedings of the National Academy of Sciences. 107(17). 7927–7932. 263 indexed citations
14.
Legleiter, Justin, Gregor P. Lotz, Ellen Sapp, et al.. (2010). Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo. Journal of Biological Chemistry. 285(19). 14777–14790. 176 indexed citations
15.
Green, Kim N., Joan S. Steffan, Hilda Martínez‐Coria, et al.. (2008). Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau. Journal of Neuroscience. 28(45). 11500–11510. 319 indexed citations
16.
Pallos, Judit, László Bodai, Tamás Lukácsovich, et al.. (2008). Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease. Human Molecular Genetics. 17(23). 3767–3775. 217 indexed citations
17.
18.
Zhang, Xiaoqian, Donna L. Smith, Anatoli B. Meriin, et al.. (2005). A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo. Proceedings of the National Academy of Sciences. 102(3). 892–897. 199 indexed citations
19.
Steffan, Joan S., Namita Agrawal, Judit Pallos, et al.. (2004). SUMO Modification of Huntingtin and Huntington's Disease Pathology. Science. 304(5667). 100–104. 547 indexed citations breakdown →
20.
Hockly, Emma, Victoria M. Richon, Donna L. Smith, et al.. (2003). Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proceedings of the National Academy of Sciences. 100(4). 2041–2046. 667 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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