Lloyd C. Trotman

10.5k total citations · 5 hit papers
44 papers, 6.4k citations indexed

About

Lloyd C. Trotman is a scholar working on Molecular Biology, Pulmonary and Respiratory Medicine and Cancer Research. According to data from OpenAlex, Lloyd C. Trotman has authored 44 papers receiving a total of 6.4k indexed citations (citations by other indexed papers that have themselves been cited), including 39 papers in Molecular Biology, 9 papers in Pulmonary and Respiratory Medicine and 8 papers in Cancer Research. Recurrent topics in Lloyd C. Trotman's work include PI3K/AKT/mTOR signaling in cancer (19 papers), Ubiquitin and proteasome pathways (10 papers) and Prostate Cancer Treatment and Research (9 papers). Lloyd C. Trotman is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (19 papers), Ubiquitin and proteasome pathways (10 papers) and Prostate Cancer Treatment and Research (9 papers). Lloyd C. Trotman collaborates with scholars based in United States, Switzerland and United Kingdom. Lloyd C. Trotman's co-authors include Pier Paolo Pandolfi, Carlos Cordon‐Cardo, Zhenbang Chen, Jason A. Koutcher, Andrea Alimonti, Zohar Dotan, Masaru Niki, Howard I. Scher, William L. Gerald and David R. Shaffer and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Lloyd C. Trotman

41 papers receiving 6.3k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

2005 1.5k citations Zhenbang Chen, Lloyd C. Trotman et al. Nature profile →
Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression

2007 593 citations Lloyd C. Trotman, Zhenbang Chen et al. profile →
NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN

2007 576 citations Lloyd C. Trotman, Zhenbang Chen et al. profile →
SUMO Modification of Huntingtin and Huntington's Disease Pathology

2004 547 citations Joan S. Steffan, Namita Agrawal et al. Science profile →
Pten Dose Dictates Cancer Progression in the Prostate

2003 531 citations Lloyd C. Trotman, Masaru Niki et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lloyd C. Trotman United States	26	5.2k	1.4k	1.1k	870	813	44	6.4k
Eugenio Santos Spain	45	5.8k 1.1×	2.2k 1.6×	1.1k 1.0×	377 0.4×	657 0.8×	154	8.3k
Kevin M. Haigis United States	42	3.9k 0.7×	2.5k 1.9×	1.0k 0.9×	540 0.6×	469 0.6×	105	6.8k
Katrina Podsypanina United States	23	5.7k 1.1×	2.1k 1.5×	1.3k 1.2×	284 0.3×	910 1.1×	36	7.4k
Peter M. Finan United Kingdom	26	5.2k 1.0×	1.2k 0.8×	1.2k 1.1×	891 1.0×	447 0.5×	40	7.6k
Antonio Di Cristofano United States	37	6.7k 1.3×	2.1k 1.5×	1.5k 1.3×	334 0.4×	1.0k 1.2×	75	9.1k
Akihiro Kurimasa Japan	36	4.8k 0.9×	1.6k 1.2×	1.2k 1.1×	775 0.9×	396 0.5×	90	6.3k
Alan P. Fields United States	54	6.1k 1.2×	1.8k 1.3×	1.1k 1.0×	349 0.4×	471 0.6×	120	7.9k
Shiaw‐Yih Lin United States	36	4.8k 0.9×	2.4k 1.8×	1.1k 1.0×	419 0.5×	525 0.6×	78	6.3k
Robert Latek United States	17	5.4k 1.0×	936 0.7×	509 0.5×	555 0.6×	387 0.5×	31	7.6k
David T. Weaver United States	49	6.5k 1.3×	2.6k 1.9×	1.3k 1.2×	459 0.5×	479 0.6×	150	9.0k

Countries citing papers authored by Lloyd C. Trotman

Since Specialization

Citations

This map shows the geographic impact of Lloyd C. Trotman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lloyd C. Trotman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lloyd C. Trotman more than expected).

Fields of papers citing papers by Lloyd C. Trotman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lloyd C. Trotman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lloyd C. Trotman. The network helps show where Lloyd C. Trotman may publish in the future.

Co-authorship network of co-authors of Lloyd C. Trotman

This figure shows the co-authorship network connecting the top 25 collaborators of Lloyd C. Trotman. A scholar is included among the top collaborators of Lloyd C. Trotman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lloyd C. Trotman. Lloyd C. Trotman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kuang, Shan, et al.. (2025). Cancer mortality and senescence: Is redox therapy an option?. Genes & Development. 39(15-16). 914–916.

Wang, Hehe, Sadhana Rajput, Diane Bogdan, et al.. (2025). Fatty acid binding protein 5 inhibitors as novel anticancer agents against metastatic castration-resistant prostate cancer. Bioorganic & Medicinal Chemistry. 122. 118136–118136.

Mathew, Grinu, Hehe Wang, Aashna Jhaveri, et al.. (2023). FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer. Cancers. 16(1). 60–60. 4 indexed citations

Froeling, Fieke E. M., et al.. (2023). Internally Controlled and Dynamic Optical Measures of Functional Tumor Biology. Analytical Chemistry. 95(13). 5661–5670. 2 indexed citations

Taranda, Julián, Grinu Mathew, Dawid G. Nowak, et al.. (2021). Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases. Cell Reports. 37(7). 110027–110027. 5 indexed citations

Froeling, Fieke E. M., Astrid Deschênes, Iok In Christine Chio, et al.. (2019). Bioactivation of Napabucasin Triggers Reactive Oxygen Species–Mediated Cancer Cell Death. Clinical Cancer Research. 25(23). 7162–7174. 58 indexed citations

Trotman, Lloyd C., et al.. (2019). PTEN: Bridging Endocytosis and Signaling. Cold Spring Harbor Perspectives in Medicine. 10(10). a036103–a036103. 15 indexed citations

Şentürk, Şerif, Nitin H. Shirole, Dawid G. Nowak, et al.. (2017). Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nature Communications. 8(1). 14370–14370. 133 indexed citations

Labbé, David P., Noriko Uetani, Laurent Lessard, et al.. (2016). PTP1B Deficiency Enables the Ability of a High-Fat Diet to Drive the Invasive Character of PTEN-Deficient Prostate Cancers. Cancer Research. 76(11). 3130–3135. 15 indexed citations

10.

Nowak, Dawid G., Hyejin Cho, Tali Herzka, et al.. (2015). MYC Drives Pten/Trp53 -Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discovery. 5(6). 636–651. 64 indexed citations

11.

Cho, Hyejin, et al.. (2015). Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome. Methods. 77-78. 197–204. 12 indexed citations

12.

Cho, Hyejin, Tali Herzka, Zheng Wu, et al.. (2014). RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc as a Driver of Pten -Mutant Metastasis. Cancer Discovery. 4(3). 318–333. 68 indexed citations

13.

Naguib, Adam, Dannielle D. Engle, Iok In Christine Chio, et al.. (2014). P53 Mutations Change Phosphatidylinositol Acyl Chain Composition. Cell Reports. 10(1). 8–19. 51 indexed citations

14.

Labbé, David P., Dawid G. Nowak, Geneviève Deblois, et al.. (2013). Prostate Cancer Genetic-susceptibility Locus on Chromosome 20q13 is Amplified and Coupled to Androgen Receptor-regulation in Metastatic Tumors. Molecular Cancer Research. 12(2). 184–189. 7 indexed citations

15.

Naguib, Adam & Lloyd C. Trotman. (2013). PTEN plasticity: how the taming of a lethal gene can go too far. Trends in Cell Biology. 23(8). 374–379. 14 indexed citations

16.

Lessard, Laurent, David P. Labbé, Geneviève Deblois, et al.. (2012). PTP1B Is an Androgen Receptor–Regulated Phosphatase That Promotes the Progression of Prostate Cancer. Cancer Research. 72(6). 1529–1537. 69 indexed citations

17.

Chen, Muhan, Christopher P. Pratt, Martha Zeeman, et al.. (2011). Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression. Cancer Cell. 20(2). 173–186. 131 indexed citations

18.

Chen, Zhenbang, Lloyd C. Trotman, David R. Shaffer, et al.. (2005). Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature. 436(7051). 725–730. 1533 indexed citations breakdown →

19.

Steffan, Joan S., Namita Agrawal, Judit Pallos, et al.. (2004). SUMO Modification of Huntingtin and Huntington's Disease Pathology. Science. 304(5667). 100–104. 547 indexed citations breakdown →

20.

Trotman, Lloyd C., et al.. (2001). Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1. Nature Cell Biology. 3(12). 1092–1100. 246 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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