Brett Langley

5.7k citations

45 papers · 4.4k indexed · 2 hit papers · h-index 31

Impact in

Molecular Biology top 2%
- Histone Deacetylase Inhibitors Research
- Muscle Physiology and Disorders
- Epigenetics and DNA Methylation
- Protein Degradation and Inhibitors
- Mitochondrial Function and Pathology
Cellular and Molecular Neuroscience top 2%
- Genetic Neurodegenerative Diseases

Papers in

Physiology 5
Cellular and Molecular Neuroscience 14
- Nerve injury and regeneration 6

Co-authors: Rajiv R. Ratan Camille Brochier Alan P. Kozikowski Ravi Kambadur Mridula Sharma Mark Thomas Amy Bishop Giulio Vistoli
Journals: Journal of Neuroscience (5 papers)ChemMedChem (3 papers)Proceedings of the National Academy of Sciences (3 papers)Journal of Biological Chemistry (2 papers)Journal of Medicinal Chemistry (2 papers)
Partner nations: United States New Zealand United Kingdom

In The Last Decade

Brett Langley

45 papers receiving 4.4k citations

Hit Papers

align trajectories log scale

Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A 2010 · 620 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Journal of the American Chemical Society
2002 Journal of Biological Chemistry

Peers

Countries citing papers authored by Brett Langley

Since Specialization

Citations

This map shows the geographic impact of Brett Langley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brett Langley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brett Langley more than expected).

Fields of papers citing papers by Brett Langley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brett Langley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brett Langley. The network helps show where Brett Langley may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Brett Langley, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brett Langley Line = papers co-authored together Brett Langley links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mild traumatic brain injury and the propensity for movement specific reinvestment International Journal of Sport and Exercise Psychology ·Liana Hategan, Liis Uiga, Brett Langley, Nick Draper, Rich S.W. Masters	2024	1
2	Elevation of NAD+ by nicotinamide riboside spares spinal cord tissue from injury and promotes locomotor recovery Experimental Neurology ·Mariajose Metcalfe, Brian T. David, Brett Langley, Caitlin E. Hill	2023	3
3	Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition The Journal of Cell Biology ·Ashley L. Kalinski, Amar N. Kar, Masayuki ONO, Andrew P. Tosolini, James N. Sleigh, Seung Joon Lee, Alicia L. Hawthorne, Diah Rasawati Kristiani, Sharmina Miller-Randolph, Ryan Passino, Liang Shi, V. Wong, Cristina Picci, Deanna S. Smith, Dianna E. Willis, Leif A. Havton, Giampietro Schiavo, Roman J. Giger, Brett Langley, Jeffery L. Twiss	2019	82
4	A brief review of recent Charcot-Marie-Tooth research and priorities F1000Research ·Sean Ekins, Nadia K. Litterman, Renée J.G. Arnold, Robert W. Burgess, Joel S. Freundlich, Steven J. Gray, Joseph Higgins, Brett Langley, Dianna E. Willis, Lucia Notterpek, David Pleasure, Michael W. Sereda, Allison Moore	2015	30
5	Antihelminthic Benzimidazoles Are Novel HIF Activators That Prevent Oxidative Neuronal Death via Binding to Tubulin Antioxidants and Redox Signaling ·Hossein Aleyasin, Saravanan S. Karuppagounder, Amit Kumar, Sama F. Sleiman, Manuela Basso, C. Thong, Ambreena Siddiq, Shankar J. Chinta, Camille Brochier, Brett Langley, Renee Haskew-Layton, Susan Bane, Gregory J. Riggins, Irina G. Gazaryan, Anatoly A. Starkov, Julie K. Andersen, Rajiv R. Ratan	2014	17
6	Sirtuin Deacetylases as Therapeutic Targets in the Nervous System Neurotherapeutics ·Brett Langley, Anthony A. Sauve	2013	29
7	A screen for inducers of p21waf1/cip1 identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties Neurobiology of Disease ·C. Thong, Brett Langley, Tomislav Reiss, Na Wei, Irina G. Gazaryan, 元貴阿野, Darrell J. Yamashiro, Dianna E. Willis, Rajiv R. Ratan	2012	24
8	Mithramycin Is a Gene-Selective Sp1 Inhibitor That Identifies a Biological Intersection between Cancer and Neurodegeneration Journal of Neuroscience ·Sama F. Sleiman, Brett Langley, Manuela Basso, Bogomil Angelov, Xia Li, W. Strecker, Madan K. Kharel, Hengchang Guo, Joan Marsh, Leslie M. Thompson, Lata Mahishi, Preeti Ahuja, W. Robb MacLellan, Daniel H. Geschwind, Giovanni Coppola, Jürgen Rohr, Rajiv R. Ratan	2011	111
9	Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway Proceedings of the National Academy of Sciences ·Renee Haskew-Layton, W. Strecker, N. A. Smirnova, C. Thong, Kelvin Chan, Timothy H. Murphy, Hengchang Guo, Brett Langley, Rukhsana Sultana, D. Allan Butterfield, Sandro Santagata, Melissa J. Alldred, Irina G. Gazaryan, George W. Bell, Stephen D. Ginsberg, Rajiv R. Ratan	2010	127
10	Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream Biochemical and Biophysical Research Communications ·Yosuke Akiba, John W. Cave, Shinobu NAKAMURA, Brett Langley, Rajiv R. Ratan, Harriet Baker	2010	12
11	Putting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions Expert Opinion on Investigational Drugs ·Sama F. Sleiman, Manuela Basso, Lata Mahishi, Alan P. Kozikowski, Mary E. Donohoe, Brett Langley, Rajiv R. Ratan	2009	63
12	Stereoselective HDAC Inhibition from Cysteine‐Derived Zinc‐Binding Groups ChemMedChem ·Kyle V. Butler, Rong He, R M S Molina, Giulio Vistoli, Brett Langley, Alan P. Kozikowski	2009	6
13	Remodeling Chromatin and Stress Resistance in the Central Nervous System: Histone Deacetylase Inhibitors as Novel and Broadly Effective Neuroprotective Agents PubMed ·Brett Langley, JoAnn Gensert, M. F. Beal, Rajiv R. Ratan	2005	141
14	Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis Journal of Neuroimmunology ·Sandra Camelo, Antonio Iglesias, Daehee Hwang, 박연호, Hoon Ryu, Karen Smith, Steven G. Gray, Jaime Imitola, Muhammad Yulian Noor, Basel T. Assaf, Brett Langley, Samia J. Khoury, George Stephanopoulos, Umberto De Girolami, Rajiv R. Ratan, Robert J. Ferrante, Fernando Dangond	2005	230
15	Proteolytic processing of myostatin is auto-regulated during myogenesis Developmental Biology ·Craig McFarlane, Brett Langley, Mark Thomas, Alex Hennebry, Erin Plummer, G. Nicholas, Chris McMahon, Mridula Sharma, Ravi Kambadur	2005	46
16	Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease Journal of Neuroscience ·Robert J. Ferrante, Hoon Ryu, James K. Kubilus, Santosh R. D’Mello, Katharine L. Sugars, Junghee Lee, Peiyuan Lu, Karen Smith, Susan Browne, M. Flint Beal, Bruce S. Kristal, Irina G. Stavrovskaya, Sandra J. Hewett, David C. Rubinsztein, Brett Langley, Rajiv R. Ratan	2004	172
17	Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway Oncogene ·Brett Langley, Mark Thomas, Craig McFarlane, Ella Ahmas, Mridula Sharma, Ravi Kambadur	2004	39
18	Novel Roles for Arginase in Cell Survival, Regeneration, and Translation in the Central Nervous System Journal of Nutrition ·Philipp S. Lange, Brett Langley, Peiyuan Lu, Rajiv R. Ratan	2004	57
19	Titin‐cap associates with, and regulates secretion of, Myostatin Journal of Cellular Physiology ·G. Nicholas, Mark Thomas, Brett Langley, W. Gregory Somers, Ketan Patel, C. Fred Kemp, Mridula Sharma, Ravi Kambadur	2002	86
20	Myostatin in Muscle Growth and Repair Exercise and Sport Sciences Reviews ·Mridula Sharma, Brett Langley, John J. Bass, Ravi Kambadur	2001	59

About Brett Langley

Brett Langley is a scholar working on Physiology, Cellular and Molecular Neuroscience, Molecular Biology, Biological Psychiatry and Cancer Research, having authored 45 papers that have together received 4.4k indexed citations. Recurring topics across this work include Histone Deacetylase Inhibitors Research (16 papers), Mitochondrial Function and Pathology (6 papers), Muscle Physiology and Disorders (6 papers), Nerve injury and regeneration (6 papers), Signaling Pathways in Disease (5 papers), Peptidase Inhibition and Analysis (4 papers), Cancer, Hypoxia, and Metabolism (4 papers) and Epigenetics and DNA Methylation (4 papers). The work is most often cited by research in Molecular Biology (3.6k citations), Cellular and Molecular Neuroscience (882 citations), Developmental Neuroscience (168 citations), Biological Psychiatry (84 citations) and Neurology (258 citations). Brett Langley has collaborated with scholars based in United States, New Zealand and United Kingdom. Frequent co-authors include Rajiv R. Ratan, Camille Brochier, Alan P. Kozikowski, Ravi Kambadur, Mridula Sharma, Mark Thomas, Amy Bishop, Giulio Vistoli, Kyle V. Butler and Jay H. Kalin. Their work appears in journals such as Journal of Neuroscience, ChemMedChem, Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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