Robert C. Spitale

9.4k total citations · 3 hit papers
96 papers, 6.2k citations indexed

About

Robert C. Spitale is a scholar working on Molecular Biology, Cancer Research and Organic Chemistry. According to data from OpenAlex, Robert C. Spitale has authored 96 papers receiving a total of 6.2k indexed citations (citations by other indexed papers that have themselves been cited), including 86 papers in Molecular Biology, 13 papers in Cancer Research and 9 papers in Organic Chemistry. Recurrent topics in Robert C. Spitale's work include RNA modifications and cancer (65 papers), RNA and protein synthesis mechanisms (60 papers) and RNA Research and Splicing (46 papers). Robert C. Spitale is often cited by papers focused on RNA modifications and cancer (65 papers), RNA and protein synthesis mechanisms (60 papers) and RNA Research and Splicing (46 papers). Robert C. Spitale collaborates with scholars based in United States, United Kingdom and Italy. Robert C. Spitale's co-authors include Howard Y. Chang, Ryan A. Flynn, Miao-Chih Tsai, Eduardo A. Torre, Yue Wan, Eric T. Kool, Qiangfeng Cliff Zhang, Eran Segal, Pete Crisalli and Kun Qu and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Robert C. Spitale

94 papers receiving 6.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Control of somatic tissue differentiation by the long non-coding RNA TINCR

2012 742 citations Markus Kretz, Zurab Siprashvili et al. Nature profile →
Structural imprints in vivo decode RNA regulatory mechanisms

2015 571 citations Robert C. Spitale, Ryan A. Flynn et al. Nature profile →
Long Intergenic Noncoding RNAs: New Links in Cancer Progression

2011 564 citations Robert C. Spitale, Howard Y. Chang et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robert C. Spitale United States	35	5.3k	2.1k	360	304	225	96	6.2k
Holger Kramer United Kingdom	35	2.6k 0.5×	625 0.3×	395 1.1×	381 1.3×	124 0.6×	82	4.0k
Denis L. J. Lafontaine Belgium	48	7.1k 1.4×	1.3k 0.6×	250 0.7×	71 0.2×	85 0.4×	101	7.7k
Yongbin Chen China	28	3.5k 0.7×	1.2k 0.6×	411 1.1×	57 0.2×	169 0.8×	61	4.5k
Philipp Mertins Germany	35	5.0k 1.0×	1.1k 0.5×	297 0.8×	80 0.3×	162 0.7×	104	6.6k
Þorkell Andrésson United States	31	2.3k 0.4×	439 0.2×	358 1.0×	161 0.5×	124 0.6×	75	3.5k
Giovanni Marsico United Kingdom	25	5.2k 1.0×	297 0.1×	267 0.7×	85 0.3×	142 0.6×	35	6.0k
Irina Gromova Denmark	37	2.7k 0.5×	591 0.3×	198 0.6×	80 0.3×	214 1.0×	83	3.8k
Thomas Arnesen Norway	40	4.8k 0.9×	952 0.5×	260 0.7×	180 0.6×	203 0.9×	107	5.8k
Júlia Costa Portugal	32	2.6k 0.5×	546 0.3×	109 0.3×	357 1.2×	133 0.6×	91	3.7k

Countries citing papers authored by Robert C. Spitale

Since Specialization

Citations

This map shows the geographic impact of Robert C. Spitale's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert C. Spitale with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert C. Spitale more than expected).

Fields of papers citing papers by Robert C. Spitale

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert C. Spitale. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert C. Spitale. The network helps show where Robert C. Spitale may publish in the future.

Co-authorship network of co-authors of Robert C. Spitale

This figure shows the co-authorship network connecting the top 25 collaborators of Robert C. Spitale. A scholar is included among the top collaborators of Robert C. Spitale based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert C. Spitale. Robert C. Spitale is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Coburn, Morgan, Ghazaleh Eskandari‐Sedighi, Jonathan Hasselmann, et al.. (2025). Human microglia differentially respond to β‐amyloid, tau, and combined Alzheimer's disease pathologies in vivo. Alzheimer s & Dementia. 21(11). e70930–e70930.

Chadarevian, Jean Paul, Jonathan Hasselmann, Christina Tu, et al.. (2024). Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy. Neuron. 112(16). 2686–2707.e8. 31 indexed citations

Yu, Angela M, Xiuye Wang, Xueyi Teng, et al.. (2023). The anticancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery. Nature Structural & Molecular Biology. 30(12). 1947–1957. 7 indexed citations

Wei, Wei, Qiongyi Zhao, Ziqi Wang, et al.. (2022). ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3. Cell Reports. 38(12). 110546–110546. 25 indexed citations

Spitale, Robert C. & Danny Incarnato. (2022). Probing the dynamic RNA structurome and its functions. Nature Reviews Genetics. 24(3). 178–196. 112 indexed citations

Engel, Krysta L., Hei‐Yong G. Lo, Raeann Goering, et al.. (2021). Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq. Nucleic Acids Research. 50(4). e24–e24. 47 indexed citations

Nguyen, Kim, Yajun Wang, Whitney England, John C. Chaput, & Robert C. Spitale. (2021). Allele-Specific RNA Knockdown with a Biologically Stable and Catalytically Efficient XNAzyme. Journal of the American Chemical Society. 143(12). 4519–4523. 30 indexed citations

Nguyen, Thai B., Whitney England, Ryan G. Lim, et al.. (2021). Huntington’s disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization. Journal of Clinical Investigation. 131(12). 39 indexed citations

Wang, Yajun, Kim Nguyen, Robert C. Spitale, & John C. Chaput. (2021). A biologically stable DNAzyme that efficiently silences gene expression in cells. Nature Chemistry. 13(4). 319–326. 177 indexed citations

10.

Claes, Christel, Emma Danhash, Jonathan Hasselmann, et al.. (2021). Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease. Molecular Neurodegeneration. 16(1). 50–50. 106 indexed citations

11.

England, Whitney, et al.. (2020). Structural disruption of exonic stem–loops immediately upstream of the intron regulates mammalian splicing. Nucleic Acids Research. 48(11). 6294–6309. 18 indexed citations

12.

England, Whitney, et al.. (2020). Chemical Approaches To Analyzing RNA Structure Transcriptome‐Wide. ChemBioChem. 22(7). 1114–1121. 6 indexed citations

13.

Bubenik, Jodi L., et al.. (2020). RNA structure probing to characterize RNA–protein interactions on low abundance pre-mRNA in living cells. RNA. 27(3). 343–358. 7 indexed citations

14.

Li, Ying, et al.. (2019). Identification of Adenosine-to-Inosine RNA Editing with Acrylonitrile Reagents. Organic Letters. 21(19). 7948–7951. 16 indexed citations

15.

Spitale, Robert C., et al.. (2018). Facile synthesis and evaluation of a dual-functioning furoyl probe for in-cell SHAPE. Bioorganic & Medicinal Chemistry Letters. 28(4). 601–605. 9 indexed citations

16.

Leighton, Laura J., Kaifu Ke, Esmi L. Zajaczkowski, et al.. (2017). Experience‐dependent neural plasticity, learning, and memory in the era of epitranscriptomics. Genes Brain & Behavior. 17(3). e12426–e12426. 26 indexed citations

17.

Flynn, Ryan A., Lance Martin, Robert C. Spitale, et al.. (2014). Dissecting noncoding and pathogen RNA–protein interactomes. RNA. 21(1). 135–143. 61 indexed citations

18.

Alfonso, Lloyd F., et al.. (2014). Molecular targets of aspirin and cancer prevention. British Journal of Cancer. 111(1). 61–67. 165 indexed citations

19.

Calo, Eliezer, Ryan A. Flynn, Lance Martin, et al.. (2014). RNA helicase DDX21 coordinates transcription and ribosomal RNA processing. Nature. 518(7538). 249–253. 231 indexed citations

20.

Kretz, Markus, Zurab Siprashvili, Ci Chu, et al.. (2012). Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 493(7431). 231–235. 742 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact