Rik van der Kant

4.9k citations

29 papers · 3.3k indexed · 4 hit papers · h-index 19

Molecular Biology top 5%
Physiology top 1%
Cell Biology top 1%
Neurology top 2%
Surgery top 10%

Co-authors: Lawrence S.B. Goldstein Rik Ossenkoppele Jacques Neefjes Lennert Janssen Oskar Hansson Hans Janssen Nuno Rocha Coenraad Kuijl
Topics: Alzheimer's disease research and treatments (11 papers)Cellular transport and secretion (8 papers)Calcium signaling and nucleotide metabolism (6 papers)
Cited by: Physiology Biological Psychiatry
Journals: Journal of Biological Chemistry Neuron The Journal of Cell Biology
Partner nations: Netherlands United States Canada

In The Last Decade

Rik van der Kant

24 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning

2009 553 citations Nuno Rocha, Coenraad Kuijl et al. profile →
Amyloid-β-independent regulators of tau pathology in Alzheimer disease

2019 423 citations Rik van der Kant, Lawrence S.B. Goldstein et al. Nature reviews. Neuroscience profile →
Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials

2022 292 citations Rik Ossenkoppele, Rik van der Kant et al. profile →
The probabilistic model of Alzheimer disease: the amyloid hypothesis revised

2021 290 citations Giovanni B. Frisoni, Daniele Altomare et al. Nature reviews. Neuroscience profile →

Peers

Countries citing papers authored by Rik van der Kant

Since Specialization

Citations

This map shows the geographic impact of Rik van der Kant's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rik van der Kant with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rik van der Kant more than expected).

Fields of papers citing papers by Rik van der Kant

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rik van der Kant. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rik van der Kant. The network helps show where Rik van der Kant may publish in the future.

Co-authorship network of co-authors of Rik van der Kant

This figure shows the co-authorship network connecting the top 25 collaborators of Rik van der Kant. A scholar is included among the top collaborators of Rik van der Kant based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rik van der Kant. Rik van der Kant is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Adult human subventricular zone microglia promote a pro-neurogenic niche for neuronal progenitors in Parkinson’s disease 2025 ·Brain Behavior and Immunity ·(unknown),(unknown),Jacqueline A. Sluijs,Bert van het Hof,Susanne M. A. van der Pol,Miriam E. van Strien,Rik van der Kant,Carlie de Vries,Helga E. de Vries,Wilma D. J. van de Berg,Elly M. Hol,Vanessa Donega	1
2	Characterization of the brain lipidome associated with frontotemporal lobar degeneration MAPT P301S mutation 2025 ·Journal of Lipid Research ·(unknown),(unknown),(unknown),Maarten Loos,Dieter Lütjohann,Martin Giera,Rik van der Kant	0
3	Protective ApoE variants support neuronal function by effluxing oxidized phospholipids 2025 ·Neuron ·Isha Ralhan,(unknown),(unknown),Femke M. Feringa,Wenqing Cai,(unknown),Ki Wai Chik,(unknown),(unknown),Rik van der Kant,Jesse Jackson,Emily L. Ricq,Maria S. Ioannou	0
4	Challenges and Opportunities for Consideration of Efavirenz Drug Repurposing for Alzheimer’s Disease Therapeutics 2024 ·ACS Pharmacology & Translational Science ·(unknown),Sonia Podvin,Barry Greenberg,Steven E. Arnold,(unknown),Rik van der Kant,Lawrence S.B. Goldstein,Jeremiah D. Momper,Anne G. Bang,James D. Silverman,Howard Feldman,Vivian Hook	4
5	Multiomics of iPSC‐derived ApoE3‐ and ApoE4 astrocytes and microglia uncovers cell type specific dysregulation of immunometabolism 2023 ·Alzheimer s & Dementia ·Rik van der Kant,(unknown),(unknown),Femke M. Feringa,(unknown),(unknown),(unknown),Amanda McQuade,Ricardo Miramontes,(unknown),(unknown),Leslie M. Thompson,Alessandro Ori‬‬,Deborah Kronenberg‐Versteeg,Yassene Mohammed,Martin Kampmann,Martin Giera	0
6	AD risk variants in APOE differentially affect lipid metabolism in iPSC derived neurons, astrocytes and microglia 2023 ·Alzheimer s & Dementia ·Femke M. Feringa,(unknown),(unknown),(unknown),(unknown),Yassene Mohammed,Martin Giera,Rik van der Kant	0
7	The probabilistic model of Alzheimer disease: the amyloid hypothesis revisedbreakdown → 2021 ·Nature reviews. Neuroscience ·Giovanni B. Frisoni,Daniele Altomare,Dietmar Rudolf Thal,Federica Ribaldi,Rik van der Kant,Rik Ossenkoppele,Kaj Blennow,Jeffrey L. Cummings,Cornelia M. van Duijn,Peter M. Nilsson,Pierre‐Yves Dietrich,Philip Scheltens,Bruno Dubois	290
8	SKIP ‐ HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport 2020 ·The EMBO Journal ·Marlieke L.M. Jongsma,Jeroen Bakker,Birol Cabukusta,Nalan Liv,Daphne M. van Elsland,Job Fermie,(unknown),Coenraad Kuijl,Sabina Y. van der Zanden,Lennert Janssen,(unknown),Rik van der Kant,Ruud H. Wijdeven,Judith Klumperman,Ilana Berlin,Jacques Neefjes	86
9	Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization 2020 ·Molecular Biology of the Cell ·Vanessa F. Langness,Rik van der Kant,Utpal Das,(unknown),(unknown),Lawrence S.B. Goldstein	34
10	Amyloid-β-independent regulators of tau pathology in Alzheimer diseasebreakdown → 2019 ·Nature reviews. Neuroscience ·Rik van der Kant,Lawrence S.B. Goldstein,Rik Ossenkoppele	423
11	Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons 2019 ·Cell stem cell ·Rik van der Kant,Vanessa F. Langness,Cheryl Herrera,(unknown),Lauren Fong,Yves Leestemaker,Evelyne Steenvoorden,Kevin D. Rynearson,Jos F. Brouwers,J. Bernd Helms,Huib Ovaa,Martin Giera,Steven L. Wagner,Anne G. Bang,Lawrence S.B. Goldstein	231
12	Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer’s Disease Mutations 2016 ·Cell Reports ·Grace Woodruff,Sol M. Reyna,Mariah Dunlap,Rik van der Kant,Julia A. Callender,Jessica E. Young,Elizabeth A. Roberts,Lawrence S.B. Goldstein	78
13	GPR43 Potentiates β-Cell Function in Obesity 2015 ·Diabetes ·Joanne McNelis,Yun Sok Lee,Rafael Mayoral,Rik van der Kant,Andrew M. Johnson,Joshua Wollam,Jerrold M. Olefsky	178
14	Cellular Functions of the Amyloid Precursor Protein from Development to Dementia 2015 ·Developmental Cell ·Rik van der Kant,Lawrence S.B. Goldstein	5
15	Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis 2015 ·Brain ·Marvin M. van Luijn,Karim L. Kreft,Marlieke L.M. Jongsma,Steven W. Mes,Annet F. Wierenga‐Wolf,Marjan van Meurs,Marie‐José Melief,Rik van der Kant,Lennert Janssen,Hans Janssen,Rusung Tan,John J. Priatel,Jacques Neefjes,Jon D. Laman,Rogier Q. Hintzen	43
16	Cellular Functions of the Amyloid Precursor Protein from Development to Dementia 2015 ·Developmental Cell ·Rik van der Kant,Lawrence S.B. Goldstein	185
17	Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity 2015 ·Journal of Biological Chemistry ·Rik van der Kant,Caspar T. H. Jonker,Ruud H. Wijdeven,Jeroen Bakker,Lennert Janssen,Judith Klumperman,Jacques Neefjes	77
18	Stuck in traffic: an emerging theme in diseases of the nervous system 2014 ·Trends in Neurosciences ·Jacques Neefjes,Rik van der Kant	73
19	Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L 2013 ·Journal of Cell Science ·Rik van der Kant,Alexander Fish,Lennert Janssen,Hans Janssen,(unknown),Nataschja I. Ho,Thijn R. Brummelkamp,Jan E. Carette,Nuno Rocha,Jacques Neefjes	160
20	Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments 2012 ·Cellular and Molecular Life Sciences ·Kristiina Uusi-Rauva,Aija Kyttälä,Rik van der Kant,Jouni Vesa,Kimmo Tanhuanpää,Jacques Neefjes,Vesa M. Olkkonen,Anu Jalanko	63

About Rik van der Kant

Rik van der Kant is a scholar working on Biological Psychiatry, Physiology and Physiology, having authored 29 papers that have together received 3.3k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (11 papers), Cellular transport and secretion (8 papers) and Calcium signaling and nucleotide metabolism (6 papers). The work is most often cited by research in Physiology (314 citations), Physiology (1.4k citations) and Biological Psychiatry (127 citations). Rik van der Kant has collaborated with scholars based in Netherlands, United States and Canada. Frequent co-authors include Lawrence S.B. Goldstein, Rik Ossenkoppele, Jacques Neefjes, Lennert Janssen, Oskar Hansson, Hans Janssen, Nuno Rocha, Coenraad Kuijl, Femke M. Feringa and Wilbert Zwart. Their work appears in journals such as Journal of Biological Chemistry, Neuron and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact