Rik van der Kant

4.9k citations

29 papers · 3.3k indexed · 4 hit papers · h-index 19

Physiology top 1%
- Alzheimer's disease research and treatments 11
- Calcium signaling and nucleotide metabolism 6
- Lysosomal Storage Disorders Research 5
Physiology top 1%
- Alzheimer's disease research and treatments 11
- Calcium signaling and nucleotide metabolism 6
- Lysosomal Storage Disorders Research 5
Biological Psychiatry top 5%
- Tryptophan and brain disorders 4
Cell Biology top 1%
- Cellular transport and secretion 8
Neurology top 2%
- Neuroinflammation and Neurodegeneration Mechanisms 5
Surgery
- Cholesterol and Lipid Metabolism 4
Psychiatry and Mental health
- Dementia and Cognitive Impairment Research 2

Co-authors: Lawrence S.B. Goldstein Rik Ossenkoppele Jacques Neefjes Lennert Janssen Oskar Hansson Hans Janssen Nuno Rocha Coenraad Kuijl
Cited by: Physiology Biological Psychiatry
Journals: Journal of Biological Chemistry (1 paper)Neuron (1 paper)The Journal of Cell Biology (1 paper)
Partner nations: Netherlands United States Canada

In The Last Decade

Rik van der Kant

24 papers receiving 3.2k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2022 The Lancet Neurology
2021 Nature reviews. Neuroscience
2019 Nature reviews. Neuroscience
2009 The Journal of Cell Biology

Peers

Countries citing papers authored by Rik van der Kant

Since Specialization

Citations

This map shows the geographic impact of Rik van der Kant's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rik van der Kant with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rik van der Kant more than expected).

Fields of papers citing papers by Rik van der Kant

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rik van der Kant. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rik van der Kant. The network helps show where Rik van der Kant may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Rik van der Kant, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Rik van der Kant Line = papers co-authored together Rik van der Kant links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Adult human subventricular zone microglia promote a pro-neurogenic niche for neuronal progenitors in Parkinson’s disease Brain Behavior and Immunity ·Sara Pecoraro,Marloes Verkerke,Jacqueline A. Sluijs,Bert van het Hof,Susanne M. A. van der Pol,Miriam E. van Strien,Rik van der Kant,Carlie de Vries,Helga E. de Vries,Wilma D. J. van de Berg,Elly M. Hol,Vanessa Donega	2025	1
2	Characterization of the brain lipidome associated with frontotemporal lobar degeneration MAPT P301S mutation Journal of Lipid Research ·Almudena Maroto Juanes,Thomas Vogels,Sascha Koppes-den Hertog,Maarten Loos,Dieter Lütjohann,Martin Giera,Rik van der Kant	2025	0
3	Protective ApoE variants support neuronal function by effluxing oxidized phospholipids Neuron ·Isha Ralhan,D. Alison,Ju-Young Bae,Femke M. Feringa,Wenqing Cai,Jinlan Chang,Ki Wai Chik,Nathanael Y.J. Lee,Christopher J Gerry,Rik van der Kant,Jesse Jackson,Emily L. Ricq,Maria S. Ioannou	2025	0
4	Challenges and Opportunities for Consideration of Efavirenz Drug Repurposing for Alzheimer’s Disease Therapeutics ACS Pharmacology & Translational Science ·Ben Boyarko,Sonia Podvin,Barry Greenberg,Steven E. Arnold,Almudena Maroto Juanes,Rik van der Kant,Lawrence S.B. Goldstein,Jeremiah D. Momper,Anne G. Bang,James D. Silverman,Howard Feldman,Vivian Hook	2024	4
5	Multiomics of iPSC‐derived ApoE3‐ and ApoE4 astrocytes and microglia uncovers cell type specific dysregulation of immunometabolism Alzheimer s & Dementia ·Rik van der Kant,Niek Blomberg,Lena Erlebach,Femke M. Feringa,Jorin Heijneman,Sascha Koppes,Iris Daphne Kruijff,Amanda McQuade,Ricardo Miramontes,Damien Olivier‐Jimenez,Aiko Robert,Leslie M. Thompson,Alessandro Ori‬‬,Deborah Kronenberg‐Versteeg,Yassene Mohammed,Martin Kampmann,Martin Giera	2023	0
6	AD risk variants in APOE differentially affect lipid metabolism in iPSC derived neurons, astrocytes and microglia Alzheimer s & Dementia ·Femke M. Feringa,Amir Abou Elmagd,Iris Daphne Kruijff,Jorin Heijneman,Sascha Koppes,Yassene Mohammed,Martin Giera,Rik van der Kant	2023	0
7	The probabilistic model of Alzheimer disease: the amyloid hypothesis revisedbreakdown → Nature reviews. Neuroscience ·Giovanni B. Frisoni,Daniele Altomare,Dietmar Rudolf Thal,Federica Ribaldi,Rik van der Kant,Rik Ossenkoppele,Kaj Blennow,Jeffrey L. Cummings,Cornelia M. van Duijn,Peter M. Nilsson,Pierre‐Yves Dietrich,Philip Scheltens,Bruno Dubois	2021	290
8	SKIP ‐ HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport The EMBO Journal ·Marlieke L.M. Jongsma,Jeroen Bakker,Birol Cabukusta,Nalan Liv,Daphne M. van Elsland,Job Fermie,Jimmy LL Akkermans,Coenraad Kuijl,Sabina Y. van der Zanden,Lennert Janssen,Denise Hoogzaad,Rik van der Kant,Ruud H. Wijdeven,Judith Klumperman,Ilana Berlin,Jacques Neefjes	2020	86
9	Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization Molecular Biology of the Cell ·Vanessa F. Langness,Rik van der Kant,Utpal Das,Louie Wang,Rodrigo dos Santos Chaves,Lawrence S.B. Goldstein	2020	34
10	Amyloid-β-independent regulators of tau pathology in Alzheimer diseasebreakdown → Nature reviews. Neuroscience ·Rik van der Kant,Lawrence S.B. Goldstein,Rik Ossenkoppele	2019	423
11	Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons Cell stem cell ·Rik van der Kant,Vanessa F. Langness,Cheryl Herrera,Daniel A. Williams,Lauren Fong,Yves Leestemaker,Evelyne Steenvoorden,Kevin D. Rynearson,Jos F. Brouwers,J. Bernd Helms,Huib Ovaa,Martin Giera,Steven L. Wagner,Anne G. Bang,Lawrence S.B. Goldstein	2019	231
12	Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer’s Disease Mutations Cell Reports ·Grace Woodruff,Sol M. Reyna,Mariah Dunlap,Rik van der Kant,Julia A. Callender,Jessica E. Young,Elizabeth A. Roberts,Lawrence S.B. Goldstein	2016	78
13	GPR43 Potentiates β-Cell Function in Obesity Diabetes ·Joanne McNelis,Yun Sok Lee,Rafael Mayoral,Rik van der Kant,Andrew M. Johnson,Joshua Wollam,Jerrold M. Olefsky	2015	178
14	Cellular Functions of the Amyloid Precursor Protein from Development to Dementia Developmental Cell ·Rik van der Kant,Lawrence S.B. Goldstein	2015	5
15	Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis Brain ·Marvin M. van Luijn,Karim L. Kreft,Marlieke L.M. Jongsma,Steven W. Mes,Annet F. Wierenga‐Wolf,Marjan van Meurs,Marie‐José Melief,Rik van der Kant,Lennert Janssen,Hans Janssen,Rusung Tan,John J. Priatel,Jacques Neefjes,Jon D. Laman,Rogier Q. Hintzen	2015	43
16	Cellular Functions of the Amyloid Precursor Protein from Development to Dementia Developmental Cell ·Rik van der Kant,Lawrence S.B. Goldstein	2015	185
17	Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity Journal of Biological Chemistry ·Rik van der Kant,Caspar T. H. Jonker,Ruud H. Wijdeven,Jeroen Bakker,Lennert Janssen,Judith Klumperman,Jacques Neefjes	2015	77
18	Stuck in traffic: an emerging theme in diseases of the nervous system Trends in Neurosciences ·Jacques Neefjes,Rik van der Kant	2014	73
19	Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L Journal of Cell Science ·Rik van der Kant,Alexander Fish,Lennert Janssen,Hans Janssen,Sabine Krom,Nataschja I. Ho,Thijn R. Brummelkamp,Jan E. Carette,Nuno Rocha,Jacques Neefjes	2013	160
20	Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments Cellular and Molecular Life Sciences ·Kristiina Uusi-Rauva,Aija Kyttälä,Rik van der Kant,Jouni Vesa,Kimmo Tanhuanpää,Jacques Neefjes,Vesa M. Olkkonen,Anu Jalanko	2012	63

About Rik van der Kant

Rik van der Kant is a scholar working on Biological Psychiatry, Physiology and Physiology, having authored 29 papers that have together received 3.3k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (11 papers), Cellular transport and secretion (8 papers), Calcium signaling and nucleotide metabolism (6 papers), Lysosomal Storage Disorders Research (5 papers), Neuroinflammation and Neurodegeneration Mechanisms (5 papers), Cholesterol and Lipid Metabolism (4 papers), Tryptophan and brain disorders (4 papers) and Dementia and Cognitive Impairment Research (2 papers). The work is most often cited by research in Physiology (314 citations), Physiology (1.4k citations) and Biological Psychiatry (127 citations). Rik van der Kant has collaborated with scholars based in Netherlands, United States and Canada. Frequent co-authors include Lawrence S.B. Goldstein, Rik Ossenkoppele, Jacques Neefjes, Lennert Janssen, Oskar Hansson, Hans Janssen, Nuno Rocha, Coenraad Kuijl, Femke M. Feringa and Wilbert Zwart. Their work appears in journals such as Journal of Biological Chemistry, Neuron and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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