Karen C. Arden

18.9k citations

77 papers · 15.0k indexed · 7 hit papers · h-index 44

Molecular Biology top 0.2%
Immunology top 1%
Oncology top 1%
Surgery top 1%
Cancer Research top 1%

Co-authors: Domenico Accili Webster K. Cavenee Michael J. Anderson William Biggs Michael J. Zigmond Azad Bonni Linda Hu Michael Z. Lin
Topics: FOXO transcription factor regulation (18 papers)Genomics and Chromatin Dynamics (10 papers)Cancer-related Molecular Pathways (9 papers)
Cited by: Aging Molecular Biology Geriatrics and Gerontology
Journals: Cell Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Belgium Germany

In The Last Decade

Karen C. Arden

77 papers receiving 14.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

1999 5.5k citations Anne Brunet, Azad Bonni et al. Cell profile →
FoxOs at the Crossroads of Cellular Metabolism, Differentiation, and Transformation

2004 1.1k citations Domenico Accili, Karen C. Arden Cell profile →
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1999 952 citations William Biggs, Webster K. Cavenee et al. profile →
The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation

2003 611 citations Jun Nakae, Tadahiro Kitamura et al. profile →
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

2004 564 citations William Biggs, Antonia Boyer et al. profile →
Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1

2002 541 citations Jun Nakae, William Biggs et al. Nature Genetics profile →
Structure, chromosomal localization, and expression of 12 genes of the MAGE family

1994 513 citations Etienne De Plaen, Catia Traversari et al. Immunogenetics profile →

Peers

Countries citing papers authored by Karen C. Arden

Since Specialization

Citations

This map shows the geographic impact of Karen C. Arden's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karen C. Arden with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karen C. Arden more than expected).

Fields of papers citing papers by Karen C. Arden

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karen C. Arden. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karen C. Arden. The network helps show where Karen C. Arden may publish in the future.

Co-authorship network of co-authors of Karen C. Arden

This figure shows the co-authorship network connecting the top 25 collaborators of Karen C. Arden. A scholar is included among the top collaborators of Karen C. Arden based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karen C. Arden. Karen C. Arden is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells 2009 ·Nature Immunology ·Anne S. Dejean,Daniel R. Beisner,Irene L. Ch’en,Yann M. Kerdiles,Anna Babour,Karen C. Arden,Diego H. Castrillón,Ronald A. DePinho,Stephen Μ. Hedrick	172
2	Guilt by association: PAX3-FOXO1 regulates gene expression through selective destabilization of the EGR1 transcription factor 2008 ·Cell Cycle ·Wendy Roeb,Antonia Boyer,Webster K. Cavenee,Karen C. Arden	13
3	Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs 2007 ·Genome Research ·Leah O. Barrera,Zirong Li,Andrew D. Smith,Karen C. Arden,Webster K. Cavenee,Michael Q. Zhang,Roland D. Green,Bing Ren	97
4	Ablation of PDK1 in pancreatic β cells induces diabetes as a result of loss of β cell mass 2006 ·Nature Genetics ·Naoko Hashimoto,Yoshiaki Kido,Tohru Uchida,Shun‐ichiro Asahara,(unknown),Tomokazu Matsuda,Akihiko Takeda,(unknown),Akihiko Nishizawa,Wataru Ogawa,(unknown),Hitoshi Okamura,Karen C. Arden,Pedro L. Herrera,Tetsuo Noda,Masato Kasuga	185
5	Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer 2006 ·Experimental Gerontology ·Karen C. Arden	115
6	FoxO 2004 ·Molecular Cell ·Karen C. Arden	99
7	Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression☆ 2003 ·Genomics ·Yao-Tseng Chen,Birgit Alpen,Toshiro Ono,Ali O. Güre,(unknown),William Biggs,Karen C. Arden,Eiichi Nakayama,Lloyd J. Old	21
8	Comprehensive karyotyping of the HT‐29 colon adenocarcinoma cell line 2002 ·Genes Chromosomes and Cancer ·Kanji Kawai,Carrie S. Viars,Karen C. Arden,David G. Jackson,Virginia Urquidi,Steve Goodison	41
9	Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1breakdown → 2002 ·Nature Genetics ·Jun Nakae,William Biggs,Tadahiro Kitamura,Webster K. Cavenee,Christopher V.E. Wright,Karen C. Arden,Domenico Accili	541
10	p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas 2000 ·Gene ·Anjali Tikoo,(unknown),Carrie S. Viars,Sara J. White,Joan K. Heath,Karen C. Arden,Hiroshi Maruta	46
11	Assignment<footref rid="foot01"><sup>1</sup></footref> of ankyrin repeat, family A (RFXANK-like) 2 (ANKRA2) to human chromosome 5q12→q13 by radiation hybrid mapping and somatic cell hybrid PCR 2000 ·Cytogenetic and Genome Research ·(unknown),Antonia Boyer,M G Farquhar,Karen C. Arden	2
12	Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factorbreakdown → 1999 ·Cell ·Anne Brunet,Azad Bonni,Michael J. Zigmond,Michael Z. Lin,Peter Juo,Linda Hu,Michael J. Anderson,Karen C. Arden,John Blenis,Michael E. Greenberg	5452
13	Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3α and β isoforms in patients with NIDDM 1997 ·Diabetologia ·Lars Hansen,Karen C. Arden,S. Rasmussen,Carrie S. Viars,Henrik Vestergaard,Torben Hansen,Ann Merete Møller,James R. Woodgett,Oluf Pedersen	33
14	Detection of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma using the reverse transcriptase-polymerase chain reaction 1996 ·Genes Chromosomes and Cancer ·Karen C. Arden,Michael J. Anderson,Friedrich Graf Finckenstein,(unknown),Webster K. Cavenee	31
15	The IL-9 Receptor Gene (IL9R): Genomic Structure, Chromosomal Localization in the Pseudoautosomal Region of the Long Arm of the Sex Chromosomes, and Identification of IL9R Pseudogenes at 9qter, 10pter, 16pter, and 18pter 1995 ·Genomics ·Abdenaim Kermouni,(unknown),Karen C. Arden,Joris Vermeesch,S B Weiss,Danièle Godelaine,Jonathan Flint,Christophe Lurquin,Jean‐Pierre Szikora,Douglas R. Higgs,Peter Marynen,Jean‐Christophe Renauld	62
16	Mutation and Expression of TP53 in Malignant Melanomas 1995 ·Recent results in cancer research ·Johannes M. Weiss,(unknown),Karen C. Arden,(unknown),Henryk Pilch,Rudolf Herbst,E. G. Jung	42
17	Structure, chromosomal localization, and expression of 12 genes of the MAGE familybreakdown → 1994 ·Immunogenetics ·Etienne De Plaen,Catia Traversari,José J. Gaforio,Jean‐Pierre Szikora,Charles De Smet,Francis Brasseur,Pierre van der Bruggen,Bernard Lethé,Christophe Lurquin,Patrick Chomez,Olivier De Backer,Thierry Boon,Karen C. Arden,Webster K. Cavenee,Robert Brasseur	513
18	Point mutations and allelic loss in the TP53 locus of cutaneous malignant melanomas 1994 ·Archives of Dermatological Research ·Johannes M. Weiss,Webster K. Cavenee,Rudolf Herbst,E. G. Jung,Karen C. Arden	11
19	The RAP1GA1 locus for human Rap1-GTPase activating protein 1 maps to chromosome 1p36.1→p35 1994 ·Cytogenetic and Genome Research ·(unknown),Bonnee Rubinfeld,Paul Polakis,Frank McCormick,Webster K. Cavenee,Karen C. Arden	6
20	Computer‐assisted image analysis of silver staining in normal and leukemic bone marrow 1989 ·International Journal of Cancer ·Karen C. Arden,C Bucana,D. A. Johnston,Sen Pathak	18

About Karen C. Arden

Karen C. Arden is a scholar working on Aging, Molecular Biology and Cancer Research, having authored 77 papers that have together received 15.0k indexed citations. Recurring topics across this work include FOXO transcription factor regulation (18 papers), Genomics and Chromatin Dynamics (10 papers) and Cancer-related Molecular Pathways (9 papers). The work is most often cited by research in Aging (1.3k citations), Molecular Biology (11.6k citations) and Geriatrics and Gerontology (583 citations). Karen C. Arden has collaborated with scholars based in United States, Belgium and Germany. Frequent co-authors include Domenico Accili, Webster K. Cavenee, Michael J. Anderson, William Biggs, Michael J. Zigmond, Azad Bonni, Linda Hu, Michael Z. Lin, Michael E. Greenberg and Peter Juo. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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