James R. Woodgett

58.4k total citations · 22 hit papers
293 papers, 47.6k citations indexed

About

James R. Woodgett is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, James R. Woodgett has authored 293 papers receiving a total of 47.6k indexed citations (citations by other indexed papers that have themselves been cited), including 248 papers in Molecular Biology, 43 papers in Cell Biology and 27 papers in Oncology. Recurrent topics in James R. Woodgett's work include Wnt/β-catenin signaling in development and cancer (100 papers), Protein Kinase Regulation and GTPase Signaling (43 papers) and Cancer-related gene regulation (41 papers). James R. Woodgett is often cited by papers focused on Wnt/β-catenin signaling in development and cancer (100 papers), Protein Kinase Regulation and GTPase Signaling (43 papers) and Cancer-related gene regulation (41 papers). James R. Woodgett collaborates with scholars based in Canada, United States and United Kingdom. James R. Woodgett's co-authors include Bradley W. Doble, John Kyriakis, Joseph Avruch, Vuk Stambolic, Eleni Nikolakaki, Philip Cohen, Elizabeth A. Rubie, Michael P. Scheid, Tony Hunter and Laurent Ruel and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

James R. Woodgett

290 papers receiving 46.8k citations

Hit Papers

The ground state of embryonic stem cell sel... 1990 2026 2002 2014 2008 1994 2003 1991 2000 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The ground state of embryonic stem cell self-renewal
    2008 2.6k citations James R. Woodgett et al. Nature profile →
  2. The stress-activated protein kinase subfamily of c-Jun kinases
    1994 2.4k citations James R. Woodgett et al. Nature profile →
  3. GSK-3: tricks of the trade for a multi-tasking kinase
    2003 1.8k citations James R. Woodgett et al. profile →
  4. Phosphorylation of c-jun mediated by MAP kinases
    1991 1.3k citations James R. Woodgett et al. Nature profile →
  5. Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
    2000 1.2k citations Ming‐Sound Tsao, James R. Woodgett et al. Nature profile →
  6. Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
    1996 1.2k citations James R. Woodgett et al. profile →
  7. Molecular cloning and expression of glycogen synthase kinase-3/factor A.
    1990 1.1k citations James R. Woodgett profile →
  8. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
    1991 949 citations James R. Woodgett et al. profile →
  9. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation
    1998 938 citations James R. Woodgett et al. profile →
  10. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
    1998 924 citations James R. Woodgett et al. Proceedings of the National Academy of Sciences profile →
  11. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
    1994 907 citations James R. Woodgett et al. Nature profile →
  12. Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A
    2000 688 citations Xianjun Fang, James R. Woodgett et al. Proceedings of the National Academy of Sciences profile →
  13. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
    2004 662 citations James R. Woodgett et al. Proceedings of the National Academy of Sciences profile →
  14. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
    1994 659 citations James R. Woodgett et al. Nature profile →
  15. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
    2005 650 citations Xin Zeng, Keiko Tamai et al. Nature profile →
  16. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
    1992 613 citations James R. Woodgett et al. profile →
  17. The stress-activated protein kinase pathways
    1999 551 citations James R. Woodgett et al. profile →
  18. Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation.
    1993 539 citations James R. Woodgett et al. profile →
  19. PKB/AKT: functional insights from genetic models
    2001 517 citations Michael P. Scheid, James R. Woodgett Nature Reviews Molecular Cell Biology profile →
  20. Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation
    1994 516 citations James R. Woodgett et al. profile →
  21. Protein Kinase B/Akt Participates in GLUT4 Translocation by Insulin in L6 Myoblasts
    1999 502 citations James R. Woodgett et al. profile →
  22. Assessment of Social Interaction Behaviors
    2011 429 citations James R. Woodgett et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
James R. Woodgett Canada 108 35.7k 5.8k 5.8k 5.7k 4.8k 293 47.6k
John Blenis United States 101 39.2k 1.1× 8.2k 1.4× 6.3k 1.1× 3.4k 0.6× 6.5k 1.3× 222 51.9k
Brian A. Hemmings Switzerland 102 33.2k 0.9× 5.1k 0.9× 7.2k 1.2× 3.0k 0.5× 3.8k 0.8× 313 42.4k
Hediye Erdjument‐Bromage United States 125 53.4k 1.5× 7.4k 1.3× 7.7k 1.3× 2.8k 0.5× 6.9k 1.4× 285 68.1k
Melanie H. Cobb United States 93 27.3k 0.8× 5.6k 1.0× 5.7k 1.0× 3.0k 0.5× 3.9k 0.8× 278 37.1k
Junying Yuan United States 103 36.5k 1.0× 5.1k 0.9× 8.1k 1.4× 4.7k 0.8× 10.4k 2.1× 254 52.9k
Keiji Tanaka Japan 112 37.9k 1.1× 7.5k 1.3× 11.5k 2.0× 3.0k 0.5× 6.8k 1.4× 428 55.1k
Gérard I. Evan United Kingdom 93 29.9k 0.8× 11.9k 2.0× 4.2k 0.7× 3.2k 0.6× 5.7k 1.2× 245 43.0k
Richard J. Youle United States 103 43.9k 1.2× 3.3k 0.6× 6.6k 1.1× 4.8k 0.8× 6.7k 1.4× 239 63.1k
Shuh Narumiya Japan 125 28.8k 0.8× 6.0k 1.0× 12.0k 2.1× 8.3k 1.5× 7.4k 1.5× 556 60.6k
Dario R. Alessi United Kingdom 124 50.6k 1.4× 7.7k 1.3× 10.1k 1.7× 4.7k 0.8× 4.9k 1.0× 313 65.6k

Countries citing papers authored by James R. Woodgett

Since Specialization
Citations

This map shows the geographic impact of James R. Woodgett's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James R. Woodgett with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James R. Woodgett more than expected).

Fields of papers citing papers by James R. Woodgett

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James R. Woodgett. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James R. Woodgett. The network helps show where James R. Woodgett may publish in the future.

Co-authorship network of co-authors of James R. Woodgett

This figure shows the co-authorship network connecting the top 25 collaborators of James R. Woodgett. A scholar is included among the top collaborators of James R. Woodgett based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James R. Woodgett. James R. Woodgett is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wang, Dong‐Yu, Zhe Jiang, Yaacov Ben‐David, James R. Woodgett, & Eldad Zacksenhaus. (2019). Molecular stratification within triple-negative breast cancer subtypes. Scientific Reports. 9(1). 19107–19107. 96 indexed citations
2.
Patterson, Andrew R., Mehari Endale, Kristin Lampe, et al.. (2018). Gimap5-dependent inactivation of GSK3β is required for CD4+ T cell homeostasis and prevention of immune pathology. Nature Communications. 9(1). 430–430. 29 indexed citations
3.
Tran, Charles W., Samuel D. Saibil, Thierry Le Bihan, et al.. (2017). Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation. The Journal of Immunology. 199(12). 4056–4065. 13 indexed citations
4.
Adams, Jessica R., Jeff C. Liu, Amanda J. Loch, et al.. (2015). Ras Signaling Is a Key Determinant for Metastatic Dissemination and Poor Survival of Luminal Breast Cancer Patients. Cancer Research. 75(22). 4960–4972. 48 indexed citations
5.
Lal, Hind, Firdos Ahmad, Jibin Zhou, et al.. (2014). Cardiac Fibroblast Glycogen Synthase Kinase-3β Regulates Ventricular Remodeling and Dysfunction in Ischemic Heart. Circulation. 130(5). 419–430. 146 indexed citations
6.
Saito, Taku, Makoto Hirata, Toshiyuki Ikeda, et al.. (2012). GSK-3α and GSK-3β Proteins Are Involved in Early Stages of Chondrocyte Differentiation with Functional Redundancy through RelA Protein Phosphorylation. Journal of Biological Chemistry. 287(35). 29227–29236. 44 indexed citations
7.
Jaworski, Tomasz, Ilse Dewachter, Benoit Lechat, et al.. (2011). GSK-3 alpha/beta kinases and amyloid production in vivo. Nature. 480(7376). 4 indexed citations
8.
Radulescu, Sorina, Rachel A. Ridgway, Paul R. Appleton, et al.. (2010). Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol. Oncogene. 29(49). 6418–6427. 24 indexed citations
9.
Dillon, Rachelle L., Richard Marcotte, Bryan T. Hennessy, et al.. (2009). Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression. Cancer Research. 69(12). 5057–5064. 148 indexed citations
10.
Liu, Shuying, Xianjun Fang, Hassan Hall, et al.. (2008). Homozygous deletion of glycogen synthase kinase 3β bypasses senescence allowing Ras transformation of primary murine fibroblasts. Proceedings of the National Academy of Sciences. 105(13). 5248–5253. 17 indexed citations
11.
Zeng, Xin, He Huang, Keiko Tamai, et al.. (2007). Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development. 135(2). 367–375. 27 indexed citations
12.
Kugimiya, Fumitaka, Hiroshi Kawaguchi, Shinsuke Ohba, et al.. (2007). GSK-3β Controls Osteogenesis through Regulating Runx2 Activity. PLoS ONE. 2(9). e837–e837. 130 indexed citations
13.
Saibil, Samuel D., Russell G. Jones, Elissa K. Deenick, et al.. (2007). CD4+ and CD8+ T Cell Survival Is Regulated Differentially by Protein Kinase Cθ, c-Rel, and Protein Kinase B. The Journal of Immunology. 178(5). 2932–2939. 41 indexed citations
14.
Hutchinson, John N., Jing Jin, Robert D. Cardiff, James R. Woodgett, & William J. Muller. (2004). Activation of Akt-1 (PKB-α) Can Accelerate ErbB-2-Mediated Mammary Tumorigenesis but Suppresses Tumor Invasion. Cancer Research. 64(9). 3171–3178. 207 indexed citations
15.
Parsons, Michael J., et al.. (2001). Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation. The Journal of Immunology. 167(1). 42–48. 68 indexed citations
16.
Scheid, Michael P. & James R. Woodgett. (2001). PKB/AKT: functional insights from genetic models. Nature Reviews Molecular Cell Biology. 2(10). 760–768. 517 indexed citations breakdown →
17.
He, Xi, Jean‐Pierre Saint‐Jeannet, James R. Woodgett, Harold Varmus, & Igor B. Dawid. (1995). Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature. 374(6523). 617–622. 431 indexed citations
18.
Woodgett, James R.. (1991). A common denominator linking glycogen metabolism, nuclear oncogenes and development. Trends in Biochemical Sciences. 16(5). 177–181. 125 indexed citations
19.
Woodgett, James R.. (1989). Use of peptide substrates for affinity purification of protein-serine kinases. Analytical Biochemistry. 180(2). 237–241. 36 indexed citations
20.
Kemp, Bruce E., Richard B. Pearson, James R. Woodgett, & Pinchas Cohen. (1985). SUBSTRATE-SPECIFICITY OF A MULTIFUNCTIONAL CALMODULIN-DEPENDENT PROTEIN-KINASE. Discovery Research Portal (University of Dundee). 44(3). 1718. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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