Domenico Accili

47.7k total citations · 13 hit papers
271 papers, 31.5k citations indexed

About

Domenico Accili is a scholar working on Molecular Biology, Surgery and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, Domenico Accili has authored 271 papers receiving a total of 31.5k indexed citations (citations by other indexed papers that have themselves been cited), including 207 papers in Molecular Biology, 152 papers in Surgery and 75 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in Domenico Accili's work include Pancreatic function and diabetes (147 papers), Metabolism, Diabetes, and Cancer (120 papers) and FOXO transcription factor regulation (75 papers). Domenico Accili is often cited by papers focused on Pancreatic function and diabetes (147 papers), Metabolism, Diabetes, and Cancer (120 papers) and FOXO transcription factor regulation (75 papers). Domenico Accili collaborates with scholars based in United States, Japan and Italy. Domenico Accili's co-authors include Jun Nakae, Tadahiro Kitamura, Karen C. Arden, Yukari Kitamura, Yoshiaki Kido, Hua Lin, Simeon I. Taylor, Rebecca A. Haeusler, C. Ronald Kahn and Shouhong Xuan and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Domenico Accili

268 papers receiving 31.0k citations

Hit Papers

Insulin-regulated hepatic... 1998 2026 2007 2016 2003 2004 2012 1998 2012 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
    2003 1.2k citations Domenico Accili et al. profile →
  2. FoxOs at the Crossroads of Cellular Metabolism, Differentiation, and Transformation
    2004 1.1k citations Domenico Accili et al. profile →
  3. Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
    2012 1.1k citations Shouhong Xuan, Hua Lin et al. profile →
  4. A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance
    1998 939 citations Domenico Accili, C. Ronald Kahn et al. profile →
  5. Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ
    2012 666 citations Domenico Accili et al. profile →
  6. The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation
    2003 611 citations Jun Nakae, Tadahiro Kitamura et al. profile →
  7. Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
    2002 541 citations Jun Nakae, Tadahiro Kitamura et al. Nature Genetics profile →
  8. Structure-based prediction of protein–protein interactions on a genome-wide scale
    2012 527 citations Domenico Accili et al. profile →
  9. SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
    2008 526 citations Alexander S. Banks, Colette M. Knight et al. Cell Metabolism profile →
  10. Biochemical and cellular properties of insulin receptor signalling
    2017 509 citations Rebecca A. Haeusler, Timothy E. McGraw et al. profile →
  11. Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver
    2007 503 citations Luciano Rossetti, Ronald A. DePinho et al. Cell Metabolism profile →
  12. Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes
    2015 418 citations Domenico Accili et al. profile →
  13. Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids
    2013 369 citations Rebecca A. Haeusler, Domenico Accili et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Domenico Accili United States 92 18.8k 10.0k 7.8k 6.8k 4.9k 271 31.5k
Morris J. Birnbaum United States 102 27.6k 1.5× 8.3k 0.8× 9.9k 1.3× 5.0k 0.7× 2.7k 0.5× 243 41.3k
Bruce E. Kemp Australia 112 31.0k 1.6× 8.7k 0.9× 11.1k 1.4× 4.7k 0.7× 1.9k 0.4× 451 44.8k
Morris F. White United States 121 32.8k 1.7× 12.4k 1.2× 11.5k 1.5× 10.6k 1.6× 4.5k 0.9× 346 51.4k
Benoı̂t Viollet France 98 27.2k 1.4× 9.7k 1.0× 9.5k 1.2× 5.3k 0.8× 1.5k 0.3× 344 42.4k
Masato Kasuga Japan 96 18.3k 1.0× 7.8k 0.8× 6.8k 0.9× 5.5k 0.8× 2.8k 0.6× 555 35.0k
Alan R. Saltiel United States 93 25.3k 1.3× 5.8k 0.6× 11.2k 1.4× 4.9k 0.7× 2.5k 0.5× 280 45.5k
E. Dale Abel United States 90 13.9k 0.7× 3.6k 0.4× 7.9k 1.0× 3.5k 0.5× 1.2k 0.2× 278 28.7k
Bernard Thorens Switzerland 88 14.1k 0.7× 10.4k 1.0× 5.2k 0.7× 8.2k 1.2× 3.7k 0.7× 261 28.2k
Philippe Froguel France 93 13.2k 0.7× 10.0k 1.0× 10.7k 1.4× 7.2k 1.1× 11.8k 2.4× 529 37.3k
Jason K. Kim United States 82 13.5k 0.7× 3.6k 0.4× 9.4k 1.2× 3.7k 0.6× 1.6k 0.3× 197 25.4k

Countries citing papers authored by Domenico Accili

Since Specialization
Citations

This map shows the geographic impact of Domenico Accili's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Domenico Accili with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Domenico Accili more than expected).

Fields of papers citing papers by Domenico Accili

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Domenico Accili. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Domenico Accili. The network helps show where Domenico Accili may publish in the future.

Co-authorship network of co-authors of Domenico Accili

This figure shows the co-authorship network connecting the top 25 collaborators of Domenico Accili. A scholar is included among the top collaborators of Domenico Accili based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Domenico Accili. Domenico Accili is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kitamoto, Takumi & Domenico Accili. (2023). Unraveling the mysteries of hepatic insulin signaling: deconvoluting the nuclear targets of insulin. Endocrine Journal. 70(9). 851–866. 1 indexed citations
2.
Park, Junhee, Jie Li, John P. Mayer, et al.. (2022). Activation of the insulin receptor by an insulin mimetic peptide. Nature Communications. 13(1). 5594–5594. 25 indexed citations
3.
Sasako, Takayoshi, T. Umehara, Kazuma Kaneko, et al.. (2022). Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice. Nature Communications. 13(1). 5655–5655. 44 indexed citations
4.
Kitamoto, Takumi, Taiyi Kuo, Atsushi Okabe, Atsushi Kaneda, & Domenico Accili. (2021). An integrative transcriptional logic model of hepatic insulin resistance. Proceedings of the National Academy of Sciences. 118(45). 11 indexed citations
5.
Bilezikian, John P., Daniel D. Bikle, Martin Hewison, et al.. (2020). MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19. European Journal of Endocrinology. 183(5). R133–R147. 260 indexed citations
6.
Haeusler, Rebecca A., Kirsten Hartil, Bhavapriya Vaitheesvaran, et al.. (2014). Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors. Nature Communications. 5(1). 5190–5190. 151 indexed citations
7.
Xuan, Shouhong, et al.. (2012). Generation of functional insulin-producing cells in the gut by Foxo1 ablation. Nature Genetics. 44(4). 406–412. 129 indexed citations
8.
González‐Roca, Eva, et al.. (2011). Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor. Proceedings of the National Academy of Sciences. 108(25). 10162–10167. 90 indexed citations
9.
Lin, Hua & Domenico Accili. (2011). Hormonal Regulation of Hepatic Glucose Production in Health and Disease. Cell Metabolism. 14(1). 9–19. 344 indexed citations
10.
Ren, Hongxia, Domenico Accili, & Cunming Duan. (2010). Hypoxia converts the myogenic action of insulin-like growth factors into mitogenic action by differentially regulating multiple signaling pathways. Proceedings of the National Academy of Sciences. 107(13). 5857–5862. 80 indexed citations
11.
Banks, Alexander S., Jianze Li, Marta Letizia Hribal, et al.. (2005). Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans. Journal of Clinical Investigation. 115(9). 2462–2471. 79 indexed citations
12.
Okamoto, Haruka, Silvana Obici, Domenico Accili, & Luciano Rossetti. (2005). Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action. Journal of Clinical Investigation. 115(5). 1314–1322. 91 indexed citations
13.
Xuan, Shouhong, Tadahiro Kitamura, Jun Nakae, et al.. (2002). Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor. Journal of Clinical Investigation. 110(7). 1011–1019. 159 indexed citations
14.
Xuan, Shouhong, Tadahiro Kitamura, Jun Nakae, et al.. (2002). Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor. Journal of Clinical Investigation. 110(7). 1011–1019. 144 indexed citations
15.
Accili, Domenico. (2001). A kinase in the life of the β cell. Journal of Clinical Investigation. 108(11). 1575–1576. 3 indexed citations
16.
Nakae, Jun, Tadahiro Kitamura, David L. Silver, & Domenico Accili. (2001). The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. Journal of Clinical Investigation. 108(9). 1359–1367. 465 indexed citations
17.
Accili, Domenico. (2000). Genetic manipulation of receptor expression and function. 19 indexed citations
18.
Asico, Laureano D., Sara Fuchs, Domenico Accili, et al.. (1998). Disruption of the dopamine D3 receptor gene produces renin-dependent hypertension.. Journal of Clinical Investigation. 102(3). 493–498. 144 indexed citations
19.
Cola, Giovanni Di, et al.. (1997). Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.. Journal of Clinical Investigation. 99(10). 2538–2544. 134 indexed citations
20.
Hurley, David M., Domenico Accili, Constantine A. Stratakis, et al.. (1991). Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.. Journal of Clinical Investigation. 87(2). 680–686. 279 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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