Sara C. Kozma

22.6k total citations · 12 hit papers
97 papers, 16.5k citations indexed

About

Sara C. Kozma is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Sara C. Kozma has authored 97 papers receiving a total of 16.5k indexed citations (citations by other indexed papers that have themselves been cited), including 86 papers in Molecular Biology, 17 papers in Oncology and 13 papers in Genetics. Recurrent topics in Sara C. Kozma's work include PI3K/AKT/mTOR signaling in cancer (31 papers), Protein Kinase Regulation and GTPase Signaling (19 papers) and RNA and protein synthesis mechanisms (13 papers). Sara C. Kozma is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (31 papers), Protein Kinase Regulation and GTPase Signaling (19 papers) and RNA and protein synthesis mechanisms (13 papers). Sara C. Kozma collaborates with scholars based in United States, Switzerland and Spain. Sara C. Kozma's co-authors include George Thomas, Patrick B. Dennis, George Thomas, Sung Hee Um, Manel Joaquin, Melanie Sticker, Nick Pullen, Stefano Fumagalli, Ernst Hafen and Hugo Stocker and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Sara C. Kozma

97 papers receiving 16.3k citations

Hit Papers

Absence of S6K1 protects ... 1994 2026 2004 2015 2004 2008 2009 2006 2003 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
    2004 1.3k citations Sung Hee Um, Melanie Sticker et al. Nature profile →
  2. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
    2008 1.1k citations Andrea Alimonti, George Thomas et al. Journal of Clinical Investigation profile →
  3. The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
    2009 1.0k citations Sara C. Kozma et al. profile →
  4. Hypothalamic mTOR Signaling Regulates Food Intake
    2006 993 citations Daniela Cota, Karine Proulx et al. Science profile →
  5. Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2
    2003 832 citations Takahiro Nobukuni, Sara C. Kozma et al. Molecular Cell profile →
  6. Mammalian TOR: A Homeostatic ATP Sensor
    2001 795 citations Patrick B. Dennis, Sara C. Kozma et al. Science profile →
  7. Phosphorylation and Activation of p70 s6k by PDK1
    1998 728 citations Nick Pullen, Patrick B. Dennis et al. Science profile →
  8. Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
    2010 718 citations Anand Selvaraj, Patrick B. Dennis et al. profile →
  9. S6K1 −/− / S6K2 −/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway
    2004 623 citations Mario Pende, Sung Hee Um et al. Molecular and Cellular Biology profile →
  10. Drosophila S6 Kinase: A Regulator of Cell Size
    1999 605 citations Sara C. Kozma, George Thomas et al. Science profile →
  11. mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
    2010 549 citations Ryan J.O. Dowling, Ivan Topisirović et al. Science profile →
  12. Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family.
    1994 534 citations Sara C. Kozma, George Thomas et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Sara C. Kozma United States 54 12.0k 2.2k 2.0k 2.0k 1.7k 97 16.5k
Thomas Franke United States 36 11.8k 1.0× 2.2k 1.0× 2.1k 1.0× 2.4k 1.2× 1.6k 0.9× 49 17.6k
Dos D. Sarbassov United States 26 12.8k 1.1× 1.6k 0.7× 2.0k 1.0× 1.8k 0.9× 1.9k 1.1× 53 16.1k
Karen C. Arden United States 44 11.6k 1.0× 1.6k 0.7× 2.1k 1.0× 2.1k 1.0× 1.0k 0.6× 77 15.0k
Christopher G. Proud United Kingdom 85 17.6k 1.5× 2.4k 1.1× 1.8k 0.9× 1.5k 0.7× 3.7k 2.2× 346 22.9k
George Thomas Switzerland 83 18.4k 1.5× 3.3k 1.5× 1.9k 0.9× 3.0k 1.5× 2.9k 1.7× 162 24.4k
Boudewijn Burgering Netherlands 64 17.6k 1.5× 2.3k 1.0× 2.4k 1.2× 3.9k 1.9× 2.1k 1.2× 155 22.7k
Ken Inoki United States 56 12.9k 1.1× 3.0k 1.3× 1.6k 0.8× 1.5k 0.8× 2.4k 1.4× 92 17.9k
Perry J. Blackshear United States 85 16.9k 1.4× 1.5k 0.7× 3.5k 1.7× 2.4k 1.2× 2.2k 1.3× 343 22.6k
Michael Leitges United States 66 7.2k 0.6× 1.3k 0.6× 3.0k 1.5× 1.5k 0.7× 1.3k 0.8× 237 12.7k
Alex Toker United States 73 15.1k 1.3× 1.4k 0.6× 2.3k 1.1× 3.1k 1.5× 3.7k 2.2× 136 20.5k

Countries citing papers authored by Sara C. Kozma

Since Specialization
Citations

This map shows the geographic impact of Sara C. Kozma's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sara C. Kozma with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sara C. Kozma more than expected).

Fields of papers citing papers by Sara C. Kozma

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sara C. Kozma. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sara C. Kozma. The network helps show where Sara C. Kozma may publish in the future.

Co-authorship network of co-authors of Sara C. Kozma

This figure shows the co-authorship network connecting the top 25 collaborators of Sara C. Kozma. A scholar is included among the top collaborators of Sara C. Kozma based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sara C. Kozma. Sara C. Kozma is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Veiga, Sónia R., Jèssica Latorre, José María Moreno‐Navarrete, et al.. (2022). A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis. JCI Insight. 7(14). 6 indexed citations
2.
Peddigari, Suresh, Carol A. Mercer, Virginia Amador, et al.. (2021). Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death. Blood. 137(24). 3351–3364. 17 indexed citations
3.
Pelletier, Joffrey, Eugènia Almacellas, Caroline Mauvezin, et al.. (2020). Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage. The EMBO Journal. 39(13). e103838–e103838. 28 indexed citations
4.
Tauler, Albert, et al.. (2019). Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content. Cancer Research. 79(17). 4348–4359. 28 indexed citations
5.
Veiga, Sónia R., Xuemei Ge, Carol A. Mercer, et al.. (2018). Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR. Clinical Cancer Research. 24(15). 3767–3780. 36 indexed citations
6.
Arif, Abul, Fulvia Terenzi, Alka A. Potdar, et al.. (2017). EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice. Nature. 542(7641). 357–361. 98 indexed citations
7.
Yi, Sang Ah, Sung Hee Um, Jaecheol Lee, et al.. (2016). S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis. Molecular Cell. 62(3). 443–452. 71 indexed citations
8.
Um, Sung Hee, Kristina Vintersten, Matthias Mueller, et al.. (2015). S6K1 controls pancreatic β cell size independently of intrauterine growth restriction. Journal of Clinical Investigation. 125(7). 2736–2747. 22 indexed citations
9.
Nardella, Caterina, Andrea Lunardi, Giuseppe Fedele, et al.. (2011). Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis. Cancer Research. 71(10). 3669–3675. 17 indexed citations
10.
Dowling, Ryan J.O., Ivan Topisirović, Tommy Alain, et al.. (2010). mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs. Science. 328(5982). 1172–1176. 549 indexed citations breakdown →
11.
McFarland-Mancini, Molly M., Andrew M. Paluch, Mingfu Zhou, et al.. (2010). Differences in Wound Healing in Mice with Deficiency of IL-6 versus IL-6 Receptor. The Journal of Immunology. 184(12). 7219–7228. 209 indexed citations
12.
Kroczyńska, Barbara, Surinder Kaur, Efstratios Katsoulidis, et al.. (2009). Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)- and Ribosomal Protein S6K-Mediated Signals. Molecular and Cellular Biology. 29(10). 2865–2875. 62 indexed citations
13.
Johansson, Gunnar, Yonatan Y. Mahller, Margaret H. Collins, et al.. (2008). Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. Molecular Cancer Therapeutics. 7(5). 1237–1245. 104 indexed citations
14.
Antion, Marcia D., Maayan Merhav, Charles A. Hoeffer, et al.. (2008). Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity. Learning & Memory. 15(1). 29–38. 115 indexed citations
15.
Kozma, Sara C., Sung Hee Um, & George Thomas. (2007). 17 Translational Control in Metabolic Diseases: The Role of mTOR Signaling in Obesity and Diabetes. Cold Spring Harbor Monograph Archive. 48. 459–483. 1 indexed citations
16.
Cota, Daniela, Karine Proulx, Sara C. Kozma, et al.. (2006). Hypothalamic mTOR Signaling Regulates Food Intake. Science. 312(5775). 927–930. 993 indexed citations breakdown →
17.
Pende, Mario, Sung Hee Um, Virginie Mieulet, et al.. (2004). S6K1 −/− / S6K2 −/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway. Molecular and Cellular Biology. 24(8). 3112–3124. 623 indexed citations breakdown →
18.
Schwab, Markus S., Sang Ho Kim, Naohiro Terada, et al.. (1999). p70 S6K Controls Selective mRNA Translation during Oocyte Maturation and Early Embryogenesis in Xenopus laevis. Molecular and Cellular Biology. 19(4). 2485–2494. 51 indexed citations
19.
Moser, Bettina A., Patrick B. Dennis, Nick Pullen, et al.. (1997). Dual Requirement for a Newly Identified Phosphorylation Site in p70 s6k. Molecular and Cellular Biology. 17(9). 5648–5655. 89 indexed citations
20.
Pearson, Richard B., Patrick B. Dennis, Jeongwoo Han, et al.. (1995). The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.. The EMBO Journal. 14(21). 5279–5287. 383 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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