Irene L. Ch’en

3.7k total citations · 1 hit paper
16 papers, 2.9k citations indexed

About

Irene L. Ch’en is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Irene L. Ch’en has authored 16 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Molecular Biology, 9 papers in Immunology and 5 papers in Oncology. Recurrent topics in Irene L. Ch’en's work include Cell death mechanisms and regulation (6 papers), Immune Cell Function and Interaction (5 papers) and T-cell and B-cell Immunology (4 papers). Irene L. Ch’en is often cited by papers focused on Cell death mechanisms and regulation (6 papers), Immune Cell Function and Interaction (5 papers) and T-cell and B-cell Immunology (4 papers). Irene L. Ch’en collaborates with scholars based in United States, France and Switzerland. Irene L. Ch’en's co-authors include Stephen Μ. Hedrick, Alexei Degterev, Junying Yuan, Gregory D. Cuny, Scott A. Gerber, Junichi Hitomi, Derek W. Abbott, Gerhard Wagner, Chengye Yuan and Alexey A. Lugovskoy and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Journal of Experimental Medicine.

In The Last Decade

Irene L. Ch’en

16 papers receiving 2.9k citations

Hit Papers

Identification of RIP1 kinase as a specific cellular targ... 2008 2026 2014 2020 2008 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Identification of RIP1 kinase as a specific cellular target of necrostatins
    2008 1.6k citations Alexei Degterev, Junichi Hitomi et al. Nature Chemical Biology profile →

Peers

Irene L. Ch’en
Duanwu Zhang China
Tomohiro Takahashi Japan
Ryan M. Genga United States
Takashi Suda Japan
Siriporn Jitkaew Thailand
Miguel A. Vega Spain
Laura L. McCormick United States
Dietrich B. Conze United States
Hugh J.M. Brady United Kingdom
Daniela Siegmund Germany
Duanwu Zhang China
Irene L. Ch’en
Citations per year, relative to Irene L. Ch’en Irene L. Ch’en (= 1×) peers Duanwu Zhang

Countries citing papers authored by Irene L. Ch’en

Since Specialization
Citations

This map shows the geographic impact of Irene L. Ch’en's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Irene L. Ch’en with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Irene L. Ch’en more than expected).

Fields of papers citing papers by Irene L. Ch’en

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Irene L. Ch’en. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Irene L. Ch’en. The network helps show where Irene L. Ch’en may publish in the future.

Co-authorship network of co-authors of Irene L. Ch’en

This figure shows the co-authorship network connecting the top 25 collaborators of Irene L. Ch’en. A scholar is included among the top collaborators of Irene L. Ch’en based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Irene L. Ch’en. Irene L. Ch’en is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

16 of 16 papers shown
1.
Davis, Lisa M., Nathan Riccitelli, Irene L. Ch’en, et al.. (2020). Monitoring of tisagenlecleucel transgene DNA using a quantitative polymerase chain reaction assay. Molecular Therapy — Methods & Clinical Development. 20. 535–541. 4 indexed citations
2.
Sarikonda, Ghanashyam, Anil Pahuja, Kevin T. Nguyen, et al.. (2020). Monitoring CAR‐T cell kinetics in clinical trials by multiparametric flow cytometry: Benefits and challenges. Cytometry Part B Clinical Cytometry. 100(1). 72–78. 21 indexed citations
3.
Chang, Chiung‐Fang, Warren N. D’Souza, Irene L. Ch’en, et al.. (2012). Polar Opposites: Erk Direction of CD4 T Cell Subsets. The Journal of Immunology. 189(2). 721–731. 69 indexed citations
4.
Kerdiles, Yann M., Erica L. Stone, Daniel R. Beisner, et al.. (2011). Foxo Transcription Factors Control Regulatory T Cell Development and Function. Immunity. 34(1). 135–135. 7 indexed citations
5.
Ch’en, Irene L., et al.. (2011). Mechanisms of necroptosis in T cells. The Journal of Experimental Medicine. 208(4). 633–641. 189 indexed citations
6.
Hedrick, Stephen Μ., et al.. (2010). Intertwined pathways of programmed cell death in immunity. Immunological Reviews. 236(1). 41–53. 35 indexed citations
7.
Kerdiles, Yann M., Erica L. Stone, Maureen A. McGargill, et al.. (2010). Foxo Transcription Factors Control Regulatory T Cell Development and Function. Immunity. 33(6). 890–904. 318 indexed citations
8.
McGargill, Maureen A., Irene L. Ch’en, Carol D. Katayama, et al.. (2009). Cutting Edge: Extracellular Signal-Related Kinase Is Not Required for Negative Selection of Developing T Cells. The Journal of Immunology. 183(8). 4838–4842. 25 indexed citations
9.
Dejean, Anne S., Daniel R. Beisner, Irene L. Ch’en, et al.. (2009). Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nature Immunology. 10(5). 504–513. 172 indexed citations
10.
Lee, Pedro, et al.. (2009). Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature. 458(7237). 519–523. 124 indexed citations
11.
Ch’en, Irene L., Daniel R. Beisner, Alexei Degterev, et al.. (2008). Antigen-mediated T cell expansion regulated by parallel pathways of death. Proceedings of the National Academy of Sciences. 105(45). 17463–17468. 117 indexed citations
12.
Ch’en, Irene L., Stephen Μ. Hedrick, & Alexander Hoffmann. (2008). Chapter 10 NF‐κB as a Determinant of Distinct Cell Death Pathways. Methods in enzymology on CD-ROM/Methods in enzymology. 446. 175–187. 6 indexed citations
13.
Degterev, Alexei, Junichi Hitomi, Irene L. Ch’en, et al.. (2008). Identification of RIP1 kinase as a specific cellular target of necrostatins. Nature Chemical Biology. 4(5). 313–321. 1603 indexed citations breakdown →
14.
Lin, Meei Yun, Tomasz Żal, Irene L. Ch’en, Nicholas R. J. Gascoigne, & Stephen Μ. Hedrick. (2005). A Pivotal Role for the Multifunctional Calcium/Calmodulin-Dependent Protein Kinase II in T Cells: From Activation to Unresponsiveness. The Journal of Immunology. 174(9). 5583–5592. 59 indexed citations
15.
Beisner, Daniel R., Irene L. Ch’en, Ravi V. Kolla, Alexander Hoffmann, & Stephen Μ. Hedrick. (2005). Cutting Edge: Innate Immunity Conferred by B Cells Is Regulated by Caspase-8. The Journal of Immunology. 175(6). 3469–3473. 142 indexed citations
16.
Wang, Ning, et al.. (2003). Expression of an engrailed-LMO4 fusion protein in mammary epithelial cells inhibits mammary gland development in mice. Oncogene. 23(8). 1507–1513. 35 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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