Jeffery D. Molkentin

79.1k total citations · 25 hit papers
430 papers, 54.9k citations indexed

About

Jeffery D. Molkentin is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Surgery. According to data from OpenAlex, Jeffery D. Molkentin has authored 430 papers receiving a total of 54.9k indexed citations (citations by other indexed papers that have themselves been cited), including 376 papers in Molecular Biology, 199 papers in Cardiology and Cardiovascular Medicine and 70 papers in Surgery. Recurrent topics in Jeffery D. Molkentin's work include Signaling Pathways in Disease (175 papers), Cardiac Fibrosis and Remodeling (106 papers) and Cardiomyopathy and Myosin Studies (65 papers). Jeffery D. Molkentin is often cited by papers focused on Signaling Pathways in Disease (175 papers), Cardiac Fibrosis and Remodeling (106 papers) and Cardiomyopathy and Myosin Studies (65 papers). Jeffery D. Molkentin collaborates with scholars based in United States, Germany and United Kingdom. Jeffery D. Molkentin's co-authors include Eric N. Olson, Jeffrey Robbins, Joerg Heineke, Orlando F. Bueno, Michelle A. Sargent, Bruce E. Markham, Marjorie Maillet, Christopher Baines, Jop H. van Berlo and Benjamin J. Wilkins and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Jeffery D. Molkentin

425 papers receiving 54.2k citations

Hit Papers

A Calcineurin-Dependent T... 1995 2026 2005 2015 1998 2005 2006 1997 2008 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
    1998 2.1k citations Jeffery D. Molkentin, Jeffrey Robbins et al. profile →
  2. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
    2005 1.8k citations Robert A. Kaiser, Nicole H. Purcell et al. profile →
  3. Regulation of cardiac hypertrophy by intracellular signalling pathways
    2006 1.5k citations Joerg Heineke, Jeffery D. Molkentin profile →
  4. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.
    1997 925 citations Jeffery D. Molkentin et al. profile →
  5. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
    2008 785 citations Jeffery D. Molkentin et al. Nature Medicine profile →
  6. Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death
    2007 759 citations Robert A. Kaiser, Jeffery D. Molkentin et al. profile →
  7. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
    2007 723 citations Jeffery D. Molkentin et al. profile →
  8. The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6
    2000 713 citations Jeffery D. Molkentin Journal of Biological Chemistry profile →
  9. Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins
    1995 707 citations Jeffery D. Molkentin et al. profile →
  10. Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis
    2017 673 citations Hadi Khalil, Robert N. Correll et al. profile →
  11. Genetic lineage tracing defines myofibroblast origin and function in the injured heart
    2016 640 citations Hadi Khalil, Jason Karch et al. profile →
  12. Calcineurin/NFAT Coupling Participates in Pathological, but not Physiological, Cardiac Hypertrophy
    2003 605 citations Benjamin J. Wilkins, Jian Xu et al. Circulation Research profile →
  13. c-kit+ cells minimally contribute cardiomyocytes to the heart
    2014 579 citations Jop H. van Berlo, Marjorie Maillet et al. profile →
  14. Cytoplasmic Signaling Pathways That Regulate Cardiac Hypertrophy
    2001 558 citations Jeffery D. Molkentin et al. profile →
  15. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
    2007 556 citations Jeffery D. Molkentin, Jeffrey Robbins et al. Nature Medicine profile →
  16. Temporally Regulated and Tissue-Specific Gene Manipulations in the Adult and Embryonic Heart Using a Tamoxifen-Inducible Cre Protein
    2001 526 citations Thomas R. Kimball, Jeffery D. Molkentin et al. Circulation Research profile →
  17. The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury
    2006 517 citations Jian Xu, Jeffery D. Molkentin et al. Circulation Research profile →
  18. Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
    2018 451 citations Hadi Khalil, Ronald J. Vagnozzi et al. profile →
  19. Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
    2012 428 citations Jeffery D. Molkentin et al. Nature Medicine profile →
  20. An acute immune response underlies the benefit of cardiac stem cell therapy
    2019 411 citations Ronald J. Vagnozzi, Marjorie Maillet et al. profile →
  21. Redefining the identity of cardiac fibroblasts
    2017 410 citations Jeffery D. Molkentin et al. profile →
  22. Molecular basis of physiological heart growth: fundamental concepts and new players
    2012 406 citations Marjorie Maillet, Jop H. van Berlo et al. profile →
  23. Cardiomyocyte Regeneration
    2017 351 citations Loren J. Field, Steven R. Houser et al. profile →
  24. Physiological and Pathological Roles of the Mitochondrial Permeability Transition Pore in the Heart
    2015 346 citations Jeffery D. Molkentin et al. profile →
  25. Cardiomyocyte Regeneration: A Consensus Statement.
    2017 315 citations Loren J. Field, Steven R. Houser et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jeffery D. Molkentin United States 124 39.3k 19.7k 7.5k 5.6k 4.0k 430 54.9k
Issei Komuro Japan 103 20.5k 0.5× 16.8k 0.9× 6.8k 0.9× 6.1k 1.1× 2.6k 0.6× 1.2k 42.9k
Kenneth R. Chien United States 110 29.4k 0.7× 15.0k 0.8× 6.9k 0.9× 3.1k 0.5× 3.4k 0.9× 303 41.1k
Joseph A. Hill United States 95 23.3k 0.6× 10.5k 0.5× 5.2k 0.7× 3.0k 0.5× 2.1k 0.5× 352 39.8k
William C. Sessa United States 112 21.5k 0.5× 8.2k 0.4× 5.4k 0.7× 16.0k 2.8× 2.4k 0.6× 336 46.8k
Stefanie Dimmeler Germany 143 42.9k 1.1× 11.7k 0.6× 15.9k 2.1× 9.6k 1.7× 6.7k 1.7× 518 73.2k
Junichi Sadoshima United States 101 20.9k 0.5× 11.2k 0.6× 2.7k 0.4× 5.8k 1.0× 2.0k 0.5× 372 36.7k
Yoshio Yazaki Japan 93 17.8k 0.5× 10.2k 0.5× 4.5k 0.6× 11.1k 2.0× 2.4k 0.6× 442 35.5k
Bradford C. Berk United States 100 16.6k 0.4× 7.2k 0.4× 3.6k 0.5× 5.9k 1.1× 2.3k 0.6× 318 29.8k
Bruce E. Kemp Australia 112 31.0k 0.8× 3.7k 0.2× 8.7k 1.2× 11.1k 2.0× 4.4k 1.1× 451 44.8k
E. Dale Abel United States 90 13.9k 0.4× 9.5k 0.5× 3.6k 0.5× 7.9k 1.4× 1.7k 0.4× 278 28.7k

Countries citing papers authored by Jeffery D. Molkentin

Since Specialization
Citations

This map shows the geographic impact of Jeffery D. Molkentin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeffery D. Molkentin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeffery D. Molkentin more than expected).

Fields of papers citing papers by Jeffery D. Molkentin

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeffery D. Molkentin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeffery D. Molkentin. The network helps show where Jeffery D. Molkentin may publish in the future.

Co-authorship network of co-authors of Jeffery D. Molkentin

This figure shows the co-authorship network connecting the top 25 collaborators of Jeffery D. Molkentin. A scholar is included among the top collaborators of Jeffery D. Molkentin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jeffery D. Molkentin. Jeffery D. Molkentin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Karch, Jason, Michael J. Bround, Hadi Khalil, et al.. (2019). Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. Science Advances. 5(8). eaaw4597–eaaw4597. 176 indexed citations
3.
Meng, Qinghang, Md. Shenuarin Bhuiyan, J. Howard James, et al.. (2018). Myofibroblast-Specific TGFβ Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy. Circulation Research. 123(12). 1285–1297. 36 indexed citations
4.
Liu, Ruijie, Jop H. van Berlo, Allen J. York, et al.. (2016). DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling. Circulation Research. 119(2). 249–260. 55 indexed citations
5.
Makarewich, Catherine A., Hongyu Zhang, Jennifer Davis, et al.. (2014). Transient Receptor Potential Channels Contribute to Pathological Structural and Functional Remodeling After Myocardial Infarction. Circulation Research. 115(6). 567–580. 97 indexed citations
6.
Drawnel, Faye, Dagmar Wachten, Jeffery D. Molkentin, et al.. (2012). IP3-induced calcium release engages a pro-hypertrophic autoamplifying loop that relieves miR-133a mediated suppression of IP3RII calcium channels. Cardiovascular Research. 93. 1 indexed citations
7.
Makarewich, Catherine A., Robert N. Correll, Hui Gao, et al.. (2012). A Caveolae-Targeted L-Type Ca 2+ Channel Antagonist Inhibits Hypertrophic Signaling Without Reducing Cardiac Contractility. Circulation Research. 110(5). 669–674. 86 indexed citations
8.
Navedo, Manuel F., Edward P. Cheng, Can Yuan, et al.. (2010). Increased Coupled Gating of L-Type Ca 2+ Channels During Hypertension and Timothy Syndrome. Circulation Research. 106(4). 748–756. 121 indexed citations
9.
Kehat, Izhak, Jennifer Davis, Malte Tiburcy, et al.. (2010). Extracellular Signal-Regulated Kinases 1 and 2 Regulate the Balance Between Eccentric and Concentric Cardiac Growth. Circulation Research. 108(2). 176–183. 197 indexed citations
10.
Millay, Douglas P., et al.. (2010). Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice. Neuromuscular Disorders. 20(11). 753–760. 54 indexed citations
11.
Heineke, Joerg, Mannix Auger‐Messier, Robert N. Correll, et al.. (2010). CIB1 is a regulator of pathological cardiac hypertrophy. Nature Medicine. 16(8). 872–879. 77 indexed citations
12.
MacDonnell, Scott M., Jutta Weisser-Thomas, Hajime Kubo, et al.. (2009). CaMKII Negatively Regulates Calcineurin–NFAT Signaling in Cardiac Myocytes. Circulation Research. 105(4). 316–325. 116 indexed citations
13.
Yang, Yong, Wei Chen, Bo Li, et al.. (2009). Rcan1 negatively regulates FcɛRI-mediated signaling and mast cell function. The Journal of Experimental Medicine. 206(1). 195–207. 30 indexed citations
14.
Heineke, Joerg, Kai C. Wollert, Hanna Osińska, et al.. (2009). Calcineurin protects the heart in a murine model of dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 48(6). 1080–1087. 35 indexed citations
15.
Martin, Lee J., Barry J. Gertz, Yan Pan, et al.. (2009). The mitochondrial permeability transition pore in motor neurons: Involvement in the pathobiology of ALS mice. Experimental Neurology. 218(2). 333–346. 155 indexed citations
16.
Nieves‐Cintrón, Madeline, Gregory C. Amberg, Manuel F. Navedo, Jeffery D. Molkentin, & Luis F. Santana. (2008). The control of Ca 2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Proceedings of the National Academy of Sciences. 105(40). 15623–15628. 95 indexed citations
17.
Snider, Paige, Robert B. Hinton, Ricardo A. Moreno‐Rodriguez, et al.. (2008). Periostin Is Required for Maturation and Extracellular Matrix Stabilization of Noncardiomyocyte Lineages of the Heart. Circulation Research. 102(7). 752–760. 269 indexed citations
18.
Purcell, Nicole H., Benjamin J. Wilkins, Allen J. York, et al.. (2007). Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proceedings of the National Academy of Sciences. 104(35). 14074–14079. 197 indexed citations
19.
Sanna, Bastiano, Eric B. Brandt, Robert A. Kaiser, et al.. (2006). Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proceedings of the National Academy of Sciences. 103(19). 7327–7332. 102 indexed citations
20.
Molkentin, Jeffery D.. (2000). The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6. Journal of Biological Chemistry. 275(50). 38949–38952. 713 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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