Nicholas E. Hoffman

3.4k total citations · 1 hit paper
27 papers, 2.2k citations indexed

About

Nicholas E. Hoffman is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Physiology. According to data from OpenAlex, Nicholas E. Hoffman has authored 27 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Molecular Biology, 6 papers in Cardiology and Cardiovascular Medicine and 5 papers in Physiology. Recurrent topics in Nicholas E. Hoffman's work include Mitochondrial Function and Pathology (8 papers), Ion channel regulation and function (5 papers) and Cardiac electrophysiology and arrhythmias (4 papers). Nicholas E. Hoffman is often cited by papers focused on Mitochondrial Function and Pathology (8 papers), Ion channel regulation and function (5 papers) and Cardiac electrophysiology and arrhythmias (4 papers). Nicholas E. Hoffman collaborates with scholars based in United States, Chile and Italy. Nicholas E. Hoffman's co-authors include Muniswamy Madesh, Harish C. Chandramoorthy, Patrick J. Doonan, Karthik Mallilankaraman, J. Kevin Foskett, Sudarsan Rajan, Rajesh Kumar Gandhirajan, César Cárdenas, Joseph Y. Cheung and Walter J. Koch and has published in prestigious journals such as Cell, Journal of Biological Chemistry and Blood.

In The Last Decade

Nicholas E. Hoffman

27 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival

2012 520 citations Karthik Mallilankaraman, Patrick J. Doonan et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Nicholas E. Hoffman United States	20	1.5k	302	294	228	201	27	2.2k
Nicola Perrotti Italy	30	1.4k 0.9×	181 0.6×	202 0.7×	113 0.5×	352 1.8×	92	2.4k
Jennifer Q. Kwong United States	23	2.5k 1.6×	375 1.2×	389 1.3×	280 1.2×	152 0.8×	43	3.3k
Karthik Mallilankaraman United States	23	2.0k 1.3×	441 1.5×	192 0.7×	391 1.7×	88 0.4×	41	3.0k
He‐Ping Ma United States	27	1.2k 0.8×	207 0.7×	135 0.5×	97 0.4×	157 0.8×	67	1.9k
Fabrice Antigny France	31	1.1k 0.7×	271 0.9×	825 2.8×	212 0.9×	338 1.7×	84	2.9k
Naomi Niisato Japan	28	1.5k 1.0×	292 1.0×	120 0.4×	226 1.0×	182 0.9×	91	2.3k
W. Keith Jones United States	27	1.7k 1.1×	405 1.3×	906 3.1×	153 0.7×	330 1.6×	43	2.9k
Michèle Sweeney United States	18	1.2k 0.8×	477 1.6×	316 1.1×	299 1.3×	416 2.1×	25	2.5k
Frank Park United States	30	1.5k 1.0×	439 1.5×	444 1.5×	182 0.8×	279 1.4×	89	2.8k
Rubén Vicente Spain	27	1.2k 0.8×	470 1.6×	366 1.2×	313 1.4×	109 0.5×	50	2.1k

Countries citing papers authored by Nicholas E. Hoffman

Since Specialization

Citations

This map shows the geographic impact of Nicholas E. Hoffman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicholas E. Hoffman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicholas E. Hoffman more than expected).

Fields of papers citing papers by Nicholas E. Hoffman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicholas E. Hoffman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicholas E. Hoffman. The network helps show where Nicholas E. Hoffman may publish in the future.

Co-authorship network of co-authors of Nicholas E. Hoffman

This figure shows the co-authorship network connecting the top 25 collaborators of Nicholas E. Hoffman. A scholar is included among the top collaborators of Nicholas E. Hoffman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicholas E. Hoffman. Nicholas E. Hoffman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Joseph, Leroy C., Grace J. Kim, Emanuele Barca, et al.. (2017). Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function. JCI Insight. 2(17). 132 indexed citations

Shanmughapriya, Santhanam, Sudarsan Rajan, Nicholas E. Hoffman, et al.. (2016). SPG7 is an Essential and Conserved Component of the Mitochondrial Permeability transition Pore. Biophysical Journal. 110(3). 309a–310a. 2 indexed citations

Feldman, Arthur M., Jennifer Gordon, JuFang Wang, et al.. (2016). BAG3 regulates contractility and Ca2+ homeostasis in adult mouse ventricular myocytes. Journal of Molecular and Cellular Cardiology. 92. 10–20. 52 indexed citations

Sathya, M., et al.. (2016). Leptospirosis Seroprevalence Among Blue Metal Mine Workers of Tamil Nadu, India. American Journal of Tropical Medicine and Hygiene. 95(1). 38–42. 17 indexed citations

Li, Xinyuan, Pu Fang, Yafeng Li, et al.. (2016). Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation. Arteriosclerosis Thrombosis and Vascular Biology. 36(6). 1090–1100. 162 indexed citations

Shanmughapriya, Santhanam, Sudarsan Rajan, Nicholas E. Hoffman, et al.. (2015). Ca ²⁺ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca ²⁺ uniporter gene MCU. Science Signaling. 8(366). ra23–ra23. 93 indexed citations

Chu, Jin, et al.. (2015). Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence. Scientific Reports. 5(1). 11086–11086. 6 indexed citations

Hoffman, Nicholas E., Barbara A. Miller, JuFang Wang, et al.. (2015). Ca²⁺entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance. American Journal of Physiology-Heart and Circulatory Physiology. 308(6). H637–H650. 53 indexed citations

Makarewich, Catherine A., Hongyu Zhang, Jennifer Davis, et al.. (2014). Transient Receptor Potential Channels Contribute to Pathological Structural and Functional Remodeling After Myocardial Infarction. Circulation Research. 115(6). 567–580. 97 indexed citations

10.

Miller, Barbara A., Nicholas E. Hoffman, Salim Merali, et al.. (2014). TRPM2 Channels Protect against Cardiac Ischemia-Reperfusion Injury. Journal of Biological Chemistry. 289(11). 7615–7629. 80 indexed citations

11.

Hoffman, Nicholas E., Harish C. Chandramoorthy, Santhanam Shanmughapriya, et al.. (2014). SLC25A23 augments mitochondrial Ca²⁺uptake, interacts with MCU, and induces oxidative stress–mediated cell death. Molecular Biology of the Cell. 25(6). 936–947. 123 indexed citations

12.

Chu, Jin, Jianguo Li, Yash B. Joshi, et al.. (2014). Gamma Secretase-Activating Protein Is a Substrate for Caspase-3: Implications for Alzheimer’s Disease. Biological Psychiatry. 77(8). 720–728. 35 indexed citations

13.

Deliu, Elena, G. Cristina Brailoiu, Satoru Eguchi, et al.. (2014). Direct evidence of intracrine angiotensin II signaling in neurons. American Journal of Physiology-Cell Physiology. 306(8). C736–C744. 18 indexed citations

14.

Huang, Z. Maggie, Erhe Gao, Fábio V. Fonseca, et al.. (2013). Convergence of G Protein–Coupled Receptor and S-Nitrosylation Signaling Determines the Outcome to Cardiac Ischemic Injury. Science Signaling. 6(299). ra95–ra95. 90 indexed citations

15.

Hoffman, Nicholas E., Harish C. Chandramoorthy, Xueqian Zhang, et al.. (2013). MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity. Cell Reports. 5(6). 1576–1588. 102 indexed citations

16.

Yu, Justine, Elena Deliu, Nicholas E. Hoffman, et al.. (2013). Differential Activation of Cultured Neonatal Cardiomyocytes by Plasmalemmal Versus Intracellular G Protein-coupled Receptor 55. Journal of Biological Chemistry. 288(31). 22481–22492. 34 indexed citations

17.

Duran, Jason M., Catherine A. Makarewich, Thomas E. Sharp, et al.. (2013). Bone-Derived Stem Cells Repair the Heart After Myocardial Infarction Through Transdifferentiation and Paracrine Signaling Mechanisms. Circulation Research. 113(5). 539–552. 139 indexed citations

18.

Vagnozzi, Ronald J., Nicholas E. Hoffman, John W. Elrod, Muniswamy Madesh, & Thomas Force. (2012). Protein kinase signaling at the crossroads of myocyte life and death in ischemic heart disease. Drug Discovery Today Therapeutic Strategies. 9(4). e173–e182. 4 indexed citations

19.

Mallilankaraman, Karthik, Patrick J. Doonan, César Cárdenas, et al.. (2012). MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival. Cell. 151(3). 630–644. 520 indexed citations breakdown →

20.

Kato, Kosuke, Erik P. Lillehoj, Yong Sung Park, et al.. (2012). Membrane-Tethered MUC1 Mucin Is Phosphorylated by Epidermal Growth Factor Receptor in Airway Epithelial Cells and Associates with TLR5 To Inhibit Recruitment of MyD88. The Journal of Immunology. 188(4). 2014–2022. 50 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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