David Klenerman

27.6k citations

320 papers · 16.1k indexed · 5 hit papers · h-index 70

Impact in

Electrochemistry top 0.1%
- Electrochemical Analysis and Applications
Bioengineering top 0.1%
- Analytical Chemistry and Sensors

Papers in

Structural Biology 14
Biophysics 51
- Advanced Fluorescence Microscopy Techniques 49

Co-authors: Yuri E. Korchev Liming Ying Shankar Balasubramanian Christopher M. Dobson Tuomas P. J. Knowles Dejian Zhou Andrew Shevchuk Mathew H. Horrocks
Journals: Biophysical Journal (31 papers)Analytical Chemistry (20 papers)Journal of the American Chemical Society (18 papers)Proceedings of the National Academy of Sciences (17 papers)Nature Communications (11 papers)
Partner nations: United Kingdom United States South Sudan

In The Last Decade

David Klenerman

311 papers receiving 15.9k citations

Hit Papers

5 papers align trajectories log scale

Single-molecule visualization of DNA G-quadruplex formation in live cells 2020 · 283 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Nature Chemistry
2019 Nature Communications
2015 Proceedings of the National Academy of Sciences
2012 Cell
2009 Nature Methods

Peers

Countries citing papers authored by David Klenerman

Since Specialization

Citations

This map shows the geographic impact of David Klenerman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Klenerman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Klenerman more than expected).

Fields of papers citing papers by David Klenerman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Klenerman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Klenerman. The network helps show where David Klenerman may publish in the future.

Co-authors

The 25 scholars most cited alongside David Klenerman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Klenerman Line = papers co-authored together David Klenerman links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Rethinking neurodegeneration through a co-proteinopathy lens Trends in Neurosciences ·Yu P. Zhang, 古沢孝男, David Klenerman	2025	0
2	Clearance of beta-amyloid and tau aggregates is size dependent and altered by an inflammatory challenge Brain Communications ·Emre Fertan, Christy Hung, John S. H. Danial, Jeff Y. L. Lam, Pranav Preman, Giulia Albertini, G. Milbrecht, Dipankar Maji, Frederick J. Livesey, Bart De Strooper, Rickie Patani, David Klenerman	2024	7
3	Detecting the Undetectable: Advances in Methods for Identifying Small Tau Aggregates in Neurodegenerative Diseases ChemBioChem ·Dipankar Maji, C. F. Kunze, Jason S. Hale, David Klenerman	2024	0
4	Single‐Molecule Characterization and Super‐Resolution Imaging of Alzheimer's Disease‐Relevant Tau Aggregates in Human Samples Angewandte Chemie ·Dipankar Maji, Dezerae Cox, Ye Nong, Jeff Y. L. Lam, Panagiotis Katsinelos, John S. H. Danial, Emre Fertan, William A. McEwan, James B. Rowe, David Klenerman	2024	2
5	High-density volumetric super-resolution microscopy Nature Communications ·Alex C. Ochoa-Siavichay, Maureen Junker-Kenny, 村尾寛之, Olga Armelia, Ruby Peters, 布川正儀, Shavkat Miralimov, Joseph S. Beckwith, Stephanie Carvalo, Ruth R. Sims, David Klenerman, Simon J. Davis, Kevin O’Holleran, Steven F. Lee	2024	15
6	Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease Nature Communications ·Derya Emin, Yu P. Zhang, Evgeniia Lobanova, Alyssa Miller, Maissan Bazazeh, Zengjie Xia, Ying Yao, M. Vijay Bhaskar Naidu, Jeff Y. L. Lam, Rohan T. Ranasinghe, Antonina Kouli, Yanyan Zhao, Suman De, Tuomas P. J. Knowles, Michele Vendruscolo, Francesco Simone Ruggeri, Franklin I. Aigbirhio, Caroline H. Williams‐Gray, David Klenerman	2022	121
7	Uncovering the universality of self-replication in protein aggregation and its link to disease Science Advances ·Georg Meisl, Catherine K. Xu, Jonathan D. Taylor, Thomas C. T. Michaels, Aviad Levin, Daniel E. Otzen, David Klenerman, Stephen Matthews, Sara Linse, Maria Andreasen, Tuomas P. J. Knowles	2022	44
8	Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging Nature Protocols ·John S. H. Danial, Jeff Y. L. Lam, C. F. Kunze, Victor Marin-Webb, Eleni Dimou, Hassoun Abed El Rahman, Derya Emin, David Klenerman	2022	26
9	CSPα reduces aggregates and rescues striatal dopamine release in α-synuclein transgenic mice Brain ·Laura Calò, Гавришина Оксана Вячеславовна, Michał Węgrzynowicz, Jeffrey W. Dalley, Bernard L. Schneider, Agnė Pacevičiūtė, Oleg Anichtchik, Emma Carlson, David Klenerman, Maria Grazia Spillantini	2021	16
10	In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease Science Advances ·Georg Meisl, Гавришина Оксана Вячеславовна, Kieren Allinson, Timothy Rittman, Sarah L. DeVos, Justin S. Sanchez, Catherine K. Xu, Karen Duff, Keith A. Johnson, James B. Rowe, Bradley T. Hyman, Tuomas P. J. Knowles, David Klenerman	2021	74
11	Deformable and Robust Core–Shell Protein Microcapsules Templated by Liquid–Liquid Phase‐Separated Microdroplets Advanced Materials Interfaces ·Yufan Xu, Yi Shen, Thomas C. T. Michaels, Kevin N. Baumann, Daniele Vigolo, Quentin Peter, Shpresim TAHIRAJ, Kadi L. Saar, Dominic Vella, Hongjia Zhu, Bing Li, He Yang, Séraphine Sawadogo Kaboré, Marc Rodriguez‐Garcia, David Klenerman, Tuomas P. J. Knowles	2021	14
12	Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation Nature Structural & Molecular Biology ·Patrick Flagmeier, Suman De, Thomas C. T. Michaels, Xiaoting Yang, Alexander J. Dear, Cecilia Emanuelsson, Michele Vendruscolo, Sara Linse, David Klenerman, Tuomas P. J. Knowles, Christopher M. Dobson	2020	47
13	A cell topography-based mechanism for ligand discrimination by the T cell receptor Proceedings of the National Academy of Sciences ·Ricardo A. Fernandes, Kristina A. Ganzinger, Justin C. Tzou, Peter Jönsson, Steven F. Lee, Matthieu Palayret, Ana Mafalda Santos, Alexander R. Carr, Aleks Ponjavic, Veronica T. Chang, 亚楠周, B. Christoffer Lagerholm, Alan E. Lindsay, Omer Dushek, T. L. WALL, Simon J. Davis, David Klenerman	2019	56
14	Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates Science Advances ·Tom Scheidt, Urszula Łapińska, Janet R. Kumita, Daniel R. Whiten, David Klenerman, Mark R. Wilson, Samuel I. A. Cohen, Sara Linse, Michele Vendruscolo, Christopher M. Dobson, Tuomas P. J. Knowles, Paolo Arosio	2019	126
15	Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms Nature Communications ·Suman De, David C. Wirthensohn, Patrick Flagmeier, Craig D. Hughes, Francesco A. Aprile, Francesco Simone Ruggeri, Daniel R. Whiten, Derya Emin, Zengjie Xia, Juan A. Varela, Pietro Sormanni, Franziska Kundel, Tuomas P. J. Knowles, Christopher M. Dobson, Clare Bryant, Michele Vendruscolo, David Klenerman Hit paper breakdown →	2019	387
16	Optical Structural Analysis of Individual α‐Synuclein Oligomers Angewandte Chemie International Edition ·Juan A. Varela, Margarida Rodrigues, Suman De, Patrick Flagmeier, Sonia Gandhi, Christopher M. Dobson, David Klenerman, Steven F. Lee	2018	31
17	Ultrasensitive Measurement of Ca²⁺ Influx into Lipid Vesicles Induced by Protein Aggregates Angewandte Chemie International Edition ·Patrick Flagmeier, Suman De, David C. Wirthensohn, Steven F. Lee, Cécile Vincke, Serge Muyldermans, Tuomas P. J. Knowles, Sonia Gandhi, Christopher M. Dobson, David Klenerman	2017	69
18	Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation Proceedings of the National Academy of Sciences ·Serene W. Chen, Srdja Drakulić, Emma Deas, Myriam Ouberaï, Francesco A. Aprile, Rocío Arranz, Henry B. Hope, Cintia Roodveldt, Tim Guilliams, Florian Jesacher, David Klenerman, Nicholas Wood, Tuomas P. J. Knowles, Carlos Alfonso, Germán Rivas, Andrey Y. Abramov, José Valpuesta, Christopher M. Dobson, Nunilo Cremades Hit paper breakdown →	2015	368
19	A mechanistic model of tau amyloid aggregation based on direct observation of oligomers Nature Communications ·Sarah L. Shammas, Gonzalo Garcia, Satish Kumar, Magnus Kjærgaard, Mathew H. Horrocks, Juan Antonio Hijano, Eva‐Maria Mandelkow, Tuomas P. J. Knowles, Eckhard Mandelkow�, David Klenerman	2015	163
20	Aldosterone acts via an ATP autocrine/paracrine system: The Edelman ATP hypothesis revisited Proceedings of the National Academy of Sciences ·Julia Gorelik, Yanjun Zhang, Daniel Sánchez, Andrew Shevchuk, Gregory I. Frolenkov, Max J. Lab, David Klenerman, Christopher R.W. Edwards, Yuri E. Korchev	2005	44

About David Klenerman

David Klenerman is a scholar working on Structural Biology, Biophysics, Electrochemistry, Bioengineering and Physiology, having authored 320 papers that have together received 16.1k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (84 papers), Advanced Fluorescence Microscopy Techniques (49 papers), Force Microscopy Techniques and Applications (40 papers), Advanced biosensing and bioanalysis techniques (40 papers), Electrochemical Analysis and Applications (33 papers), Parkinson's Disease Mechanisms and Treatments (29 papers), Microfluidic and Bio-sensing Technologies (25 papers) and Analytical Chemistry and Sensors (23 papers). The work is most often cited by research in Electrochemistry (2.2k citations), Bioengineering (1.4k citations), Biophysics (1.4k citations), Structural Biology (350 citations) and Physiology (3.8k citations). David Klenerman has collaborated with scholars based in United Kingdom, United States and South Sudan. Frequent co-authors include Yuri E. Korchev, Liming Ying, Shankar Balasubramanian, Christopher M. Dobson, Tuomas P. J. Knowles, Dejian Zhou, Andrew Shevchuk, Mathew H. Horrocks, Richard W. Clarke and Andreas Bruckbauer. Their work appears in journals such as Biophysical Journal, Analytical Chemistry, Journal of the American Chemical Society, Proceedings of the National Academy of Sciences and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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