Christopher M. Dobson

118.4k citations

839 papers · 95.2k indexed · 42 hit papers · h-index 143

Impact in

Physiology top 0.01%
- Alzheimer's disease research and treatments
Molecular Biology top 0.01%
- Protein Structure and Dynamics
- Prion Diseases and Protein Misfolding
- RNA and protein synthesis mechanisms

Papers in

Physiology 285
- Alzheimer's disease research and treatments 272
Spectroscopy 147
- Advanced NMR Techniques and Applications 88

Co-authors: Fabrizio Chiti Michele Vendruscolo Tuomas P. J. Knowles Massimo Stefani Carol V. Robinson Jesús Zurdo Martin Karplus Niccolò Taddei
Journals: Journal of Molecular Biology (77 papers)Proceedings of the National Academy of Sciences (61 papers)Biochemistry (53 papers)Journal of the American Chemical Society (51 papers)Biophysical Journal (33 papers)
Partner nations: United Kingdom United States Italy

In The Last Decade

Christopher M. Dobson

832 papers receiving 93.5k citations

Hit Papers

15 papers align trajectories log scale

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells 2021 · 166 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Nature Communications
2020 Nature Chemistry
2020 Chemical Society Reviews
2019 Nature Communications
2017 Science
2017 Annual Review of Biochemistry
2016 Nature Protocols
2015 Proceedings of the National Academy of Sciences
2015 Nature Chemical Biology
2014 Proceedings of the National Academy of Sciences
2014 Nature Reviews Molecular Cell Biology
2014 Proceedings of the National Academy of Sciences
2013 Proceedings of the National Academy of Sciences
2013 Proceedings of the National Academy of Sciences
2012 Cell
2009 Science
2008 Nature Chemical Biology
2007 Science
2006 Proceedings of the National Academy of Sciences
2006 Annual Review of Biochemistry
2005 Journal of Molecular Biology
2005 Nature Cell Biology
2004 Journal of the American Chemical Society
2004 Nature
2004 Seminars in Cell and Developmental Biology
2003 Journal of Molecular Medicine
2003 Nature
2003 Nature
2002 Nature
2002 Science
2002 Proceedings of the National Academy of Sciences
2001 Nature
2001 Philosophical Transactions of the Royal Society B Biological Sciences
1999 Biochemistry
1999 Proceedings of the National Academy of Sciences
1999 Trends in Biochemical Sciences
1998 Angewandte Chemie International Edition
1998 Proceedings of the National Academy of Sciences
1997 Nature
1994 Cement and Concrete Research
1993 Science
1992 Nature

Peers

Countries citing papers authored by Christopher M. Dobson

Since Specialization

Citations

This map shows the geographic impact of Christopher M. Dobson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher M. Dobson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher M. Dobson more than expected).

Fields of papers citing papers by Christopher M. Dobson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher M. Dobson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher M. Dobson. The network helps show where Christopher M. Dobson may publish in the future.

Co-authors

The 25 scholars most cited alongside Christopher M. Dobson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher M. Dobson Line = papers co-authored together Christopher M. Dobson links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends Nature Communications ·Matthias M. Schneider, Saurabh Gautam, Therese W. Herling, Ewa Andrzejewska, Georg Krainer, Alyssa Miller, Victoria A. Trinkaus, Quentin Peter, Francesco Simone Ruggeri, Michele Vendruscolo, Andreas Bracher, Christopher M. Dobson, F. Ulrich Hartl, Tuomas P. J. Knowles	2021	53
2	A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers Communications Biology ·Rodrigo Cataldi, Sean Chia, Lizhi YANG, Francesco Simone Ruggeri, Catherine K. Xu, Tomas Šneideris, Michele Perni, Erin Spelman, Priyanka Joshi, Janet R. Kumita, Sara Linse, Johnny Habchi, Tuomas P. J. Knowles, Benedetta Mannini, Christopher M. Dobson, Michele Vendruscolo	2021	36
3	Machine learning-aided protein identification from multidimensional signatures Lab on a Chip ·Silvia Leticia Sánchez Fuentes, NI Fu-sheng, Kadi L. Saar, Pavan K. Challa, Alexey S. Morgunov, Quentin Peter, Sean R. A. Devenish, Christopher M. Dobson, Khaled Abdel Haleim Al-Shewy	2021	7
4	Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies Journal of Molecular Cell Biology ·Maarten C. Hardenberg, Tessa Sinnige, Seung Jong Lee, هبه عبداللطيف رجا مصطفى, Chetan Poudel, Elizabeth A. Robinson, Mónika Fuxreiter, A.M. Turky, Clemens F. Kaminski, Ellen A. A. Nollen, Christopher M. Dobson, Michele Vendruscolo	2020	78
5	Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation Nature Structural & Molecular Biology ·Patrick Flagmeier, Suman De, Thomas C. T. Michaels, Xiaoting Yang, Alexander J. Dear, Cecilia Emanuelsson, Michele Vendruscolo, Sara Linse, David Klenerman, Tuomas P. J. Knowles, Christopher M. Dobson	2020	47
6	On-chip measurements of protein unfolding from direct observations of micron-scale diffusion Chemical Science ·Silvia Leticia Sánchez Fuentes, Emma V. Yates, Liu Hong, Kadi L. Saar, Georg Meisl, Christopher M. Dobson, Tuomas P. J. Knowles	2018	9
7	Structural differences between toxic and nontoxic HypF-N oligomers Chemical Communications ·Claudia Capitini, Muhand Ali A Asseri, Antonino Natalello, Cristiano D’Andrea, Annalisa Relini, James A. Jarvis, Leila Birolo, 達哉海野, Michele Vendruscolo, Paolo Matteini, Christopher M. Dobson, Alfonso De Simone, Fabrizio Chiti	2018	26
8	Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade Annual Review of Biochemistry ·Fabrizio Chiti, Christopher M. Dobson Hit paper breakdown →	2017	1966
9	Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers Science ·Giuliana Fusco, Serene W. Chen, Philip T. F. Williamson, Roberta Cascella, Michele Perni, James A. Jarvis, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti, Nunilo Cremades, Liming Ying, Christopher M. Dobson, Alfonso De Simone Hit paper breakdown →	2017	520
10	Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation Proceedings of the National Academy of Sciences ·Serene W. Chen, Srdja Drakulić, Emma Deas, Myriam Ouberaï, Francesco A. Aprile, Rocío Arranz, Henry B. Hope, Cintia Roodveldt, Tim Guilliams, Florian Jesacher, David Klenerman, Nicholas Wood, Tuomas P. J. Knowles, Carlos Alfonso, Germán Rivas, Andrey Y. Abramov, José Valpuesta, Christopher M. Dobson, Nunilo Cremades Hit paper breakdown →	2015	368
11	The N-terminus of amyloid-beta plays a crucial role in its aggregation and toxicity Research Online (University of Wollongong) ·Benedetta Bolognesi, Thomas R. Jahn, Ann‐Christin Brorsson, Leila M. Luheshi, Justin J. Yerbury, Damian C. Crowther, Christopher M. Dobson	2010	1
12	An Analytical Solution to the Kinetics of Breakable Filament Assembly Science ·Tuomas P. J. Knowles, Christopher A. Waudby, Glyn L. Devlin, Samuel I. A. Cohen, Adriano Aguzzi, Michele Vendruscolo, Eugene M. Terentjev, Mark E. Welland, Christopher M. Dobson Hit paper breakdown →	2009	899
13	Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation Proceedings of the National Academy of Sciences ·Natàlia Carulla, Min Zhou, Muriel Arimon, Margarida Gairí, Ernest Giralt, Carol V. Robinson, Christopher M. Dobson	2009	94
14	Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy Proceedings of the National Academy of Sciences ·Shang‐Te Danny Hsu, Paola Fucini, Lisa D. Cabrita, Hélène Launay, Christopher M. Dobson, John Christodoulou	2007	99
15	Protein structure determination from NMR chemical shifts Proceedings of the National Academy of Sciences ·Andrea Cavalli, Xavier Salvatella, Christopher M. Dobson, Michele Vendruscolo	2007	419
16	Hereditary systemic amyloidosis associated with mutational variants of human lysozyme Open Repository and Bibliography (University of Liège) ·Mireille Dumoulin, Vittorio Bellotti, Christopher M. Dobson	2005	2
17	Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril Proceedings of the National Academy of Sciences ·Christopher P. Jaroniec, Cait E. MacPhee, Nathan S. Astrof, Christopher M. Dobson, Robert G. Griffin	2002	214
18	Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases Proceedings of the National Academy of Sciences ·Fabrizio Chiti, Martino Calamai, Niccolò Taddei, Massimo Stefani, Giampietro Ramponi, Christopher M. Dobson	2002	229
19	Assignment of the 1H n.m.r. spectra of proteins Proceedings of the Royal Society of London A Mathematical and Physical Sciences ·Iain D. Campbell, Christopher M. Dobson, Robert J. P. Williams	1975	42
20	Nuclear magnetic resonance studies on the structure of lysozyme in solution Proceedings of the Royal Society of London A Mathematical and Physical Sciences ·Iain D. Campbell, Christopher M. Dobson, Robert J. P. Williams	1975	55

About Christopher M. Dobson

Christopher M. Dobson is a scholar working on Physiology, Spectroscopy, Molecular Biology, Aging and Cell Biology, having authored 839 papers that have together received 95.2k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (369 papers), Alzheimer's disease research and treatments (272 papers), Enzyme Structure and Function (198 papers), Prion Diseases and Protein Misfolding (110 papers), Advanced NMR Techniques and Applications (88 papers), Parkinson's Disease Mechanisms and Treatments (73 papers), RNA and protein synthesis mechanisms (55 papers) and Endoplasmic Reticulum Stress and Disease (51 papers). The work is most often cited by research in Physiology (35.8k citations), Molecular Biology (65.7k citations), Biomaterials (11.3k citations), Neurology (9.3k citations) and Cell Biology (9.9k citations). Christopher M. Dobson has collaborated with scholars based in United Kingdom, United States and Italy. Frequent co-authors include Fabrizio Chiti, Michele Vendruscolo, Tuomas P. J. Knowles, Massimo Stefani, Carol V. Robinson, Jesús Zurdo, Martin Karplus, Niccolò Taddei, Samuel I. A. Cohen and Giampietro Ramponi. Their work appears in journals such as Journal of Molecular Biology, Proceedings of the National Academy of Sciences, Biochemistry, Journal of the American Chemical Society and Biophysical Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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