Ehud Y. Isacoff

23.6k total citations · 6 hit papers
192 papers, 18.6k citations indexed

About

Ehud Y. Isacoff is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Materials Chemistry. According to data from OpenAlex, Ehud Y. Isacoff has authored 192 papers receiving a total of 18.6k indexed citations (citations by other indexed papers that have themselves been cited), including 145 papers in Cellular and Molecular Neuroscience, 135 papers in Molecular Biology and 34 papers in Materials Chemistry. Recurrent topics in Ehud Y. Isacoff's work include Photoreceptor and optogenetics research (69 papers), Ion channel regulation and function (60 papers) and Neuroscience and Neuropharmacology Research (59 papers). Ehud Y. Isacoff is often cited by papers focused on Photoreceptor and optogenetics research (69 papers), Ion channel regulation and function (60 papers) and Neuroscience and Neuropharmacology Research (59 papers). Ehud Y. Isacoff collaborates with scholars based in United States, Germany and France. Ehud Y. Isacoff's co-authors include Maximilian H. Ulbrich, Dirk Trauner, Christopher J. Chang, Arnd Pralle, Pau Gorostiza, Francesco Tombola, Evan W. Miller, Lidia M. Mannuzzu, Richard Krämer and Lily Yeh Jan and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Ehud Y. Isacoff

187 papers receiving 18.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells

2005 738 citations Arnd Pralle, Ehud Y. Isacoff et al. Journal of the American Chemical Society profile →
Light-activated ion channels for remote control of neuronal firing

2004 589 citations Ehud Y. Isacoff, Dirk Trauner et al. profile →
A Selective, Cell-Permeable Optical Probe for Hydrogen Peroxide in Living Cells

2004 571 citations Arnd Pralle, Ehud Y. Isacoff et al. Journal of the American Chemical Society profile →
Subunit counting in membrane-bound proteins

2007 538 citations Ehud Y. Isacoff et al. profile →
Boronate-Based Fluorescent Probes for Imaging Cellular Hydrogen Peroxide

2005 511 citations Arnd Pralle, Ehud Y. Isacoff et al. Journal of the American Chemical Society profile →
Direct Physical Measure of Conformational Rearrangement Underlying Potassium Channel Gating

1996 504 citations Ehud Y. Isacoff et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ehud Y. Isacoff United States	75	11.1k	10.3k	3.5k	2.4k	1.7k	192	18.6k
Lubert Stryer United States	78	20.4k 1.8×	7.5k 0.7×	2.6k 0.7×	819 0.3×	3.6k 2.1×	276	27.9k
Eric Gouaux United States	76	17.0k 1.5×	10.9k 1.1×	1.2k 0.3×	428 0.2×	745 0.4×	141	23.4k
Henry A. Lester United States	86	19.0k 1.7×	12.5k 1.2×	752 0.2×	1.7k 0.7×	864 0.5×	371	25.0k
Graham C. R. Ellis‐Davies United States	47	4.3k 0.4×	7.8k 0.8×	2.8k 0.8×	549 0.2×	882 0.5×	123	11.7k
Leslie M. Loew United States	60	6.3k 0.6×	3.8k 0.4×	848 0.2×	1.0k 0.4×	1.0k 0.6×	230	12.6k
Krzysztof Palczewski United States	104	34.6k 3.1×	17.7k 1.7×	1.7k 0.5×	445 0.2×	2.9k 1.7×	578	39.9k
Martin Poenie United States	30	15.7k 1.4×	8.2k 0.8×	564 0.2×	2.0k 0.8×	2.3k 1.4×	43	25.2k
Roderick MacKinnon United States	95	36.7k 3.3×	16.5k 1.6×	1.6k 0.5×	13.1k 5.4×	2.0k 1.2×	168	42.8k
Jin Zhang United States	60	10.6k 0.9×	2.2k 0.2×	838 0.2×	850 0.4×	1.7k 1.0×	366	15.4k
Angus C. Nairn United States	111	26.5k 2.4×	14.2k 1.4×	932 0.3×	1.7k 0.7×	6.1k 3.6×	478	39.4k

Countries citing papers authored by Ehud Y. Isacoff

Since Specialization

Citations

This map shows the geographic impact of Ehud Y. Isacoff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ehud Y. Isacoff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ehud Y. Isacoff more than expected).

Fields of papers citing papers by Ehud Y. Isacoff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ehud Y. Isacoff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ehud Y. Isacoff. The network helps show where Ehud Y. Isacoff may publish in the future.

Co-authorship network of co-authors of Ehud Y. Isacoff

This figure shows the co-authorship network connecting the top 25 collaborators of Ehud Y. Isacoff. A scholar is included among the top collaborators of Ehud Y. Isacoff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ehud Y. Isacoff. Ehud Y. Isacoff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Read, Jordan S., Cherise Stanley, Meike Visel, et al.. (2025). Dopamine D1 receptor activation in the striatum is sufficient to drive reinforcement of anteceding cortical patterns. Neuron. 113(5). 785–794.e9. 2 indexed citations

Choi, Yoon Gi, et al.. (2025). Deficiency in transmitter release triggers homeostatic transcriptional changes that increase presynaptic excitability. Proceedings of the National Academy of Sciences. 122(31). e2322714122–e2322714122.

Kumar, Kaavya Krishna, Haoqing Wang, Chris Habrian, et al.. (2024). Stepwise activation of a metabotropic glutamate receptor. Nature. 629(8013). 951–956. 19 indexed citations

Natan, Ryan G., Wei Chen, Amy Winans, et al.. (2024). Modal focal adaptive optics for Bessel-focus two-photon fluorescence microscopy. Optics Express. 33(1). 680–680. 1 indexed citations

Ge, Xinxin, et al.. (2024). Frequency-multiplexed aberration measurement for confocal microscopy. Optics Express. 32(16). 28655–28655.

Liu, William, R Steven Stowers, Adam Hoagland, et al.. (2024). Synapse-specific catecholaminergic modulation of neuronal glutamate release. Proceedings of the National Academy of Sciences. 122(1). e2420496121–e2420496121. 2 indexed citations

Lin, Zhang, et al.. (2024). Coupling sensor to enzyme in the voltage sensing phosphatase. Nature Communications. 15(1). 6409–6409. 2 indexed citations

Habrian, Chris, Naomi R. Latorraca, Zhu Fu, & Ehud Y. Isacoff. (2023). Homo- and hetero-dimeric subunit interactions set affinity and efficacy in metabotropic glutamate receptors. Nature Communications. 14(1). 8288–8288. 10 indexed citations

Ge, Xinxin, et al.. (2023). Frequency-multiplexed aberration measurement and correction for confocal microscopy (Conference Presentation). 36–36. 1 indexed citations

10.

Newman, Zachary L., Samuel J. Kenny, Seonah Moon, et al.. (2022). Determinants of synapse diversity revealed by super-resolution quantal transmission and active zone imaging. Nature Communications. 13(1). 229–229. 34 indexed citations

11.

Vyklický, Vojtěch, Cherise Stanley, Chris Habrian, & Ehud Y. Isacoff. (2021). Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation. Nature Communications. 12(1). 2694–2694. 14 indexed citations

12.

Li, Ziwei, Qinrong Zhang, Zachary L. Newman, et al.. (2020). Fast widefield imaging of neuronal structure and function with optical sectioning in vivo. Science Advances. 6(19). eaaz3870–eaaz3870. 48 indexed citations

13.

Morstein, Johannes, Derek D. Norman, Prashant Donthamsetti, et al.. (2020). Optical Control of Lysophosphatidic Acid Signaling. Journal of the American Chemical Society. 142(24). 10612–10616. 37 indexed citations

14.

Habrian, Chris, Joshua Levitz, Vojtěch Vyklický, et al.. (2019). Conformational pathway provides unique sensitivity to a synaptic mGluR. Nature Communications. 10(1). 5572–5572. 51 indexed citations

15.

Accanto, Nicolò, Dimitrii Tanese, Emiliano Ronzitti, et al.. (2018). Multiplexed temporally focused light shaping for high-resolution multi-cell targeting. Optica. 5(11). 1478–1478. 30 indexed citations

16.

Xiao, Tong, Cheri M. Ackerman, Elizabeth C. Carroll, et al.. (2018). Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system. Nature Chemical Biology. 14(7). 655–663. 127 indexed citations

17.

Gaub, Benjamin M., Michael H. Berry, Amy Holt, et al.. (2014). Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells. Proceedings of the National Academy of Sciences. 111(51). E5574–83. 95 indexed citations

18.

Berger, Thomas K. & Ehud Y. Isacoff. (2011). The Pore of the Voltage-Gated Proton Channel. Neuron. 72(6). 991–1000. 57 indexed citations

19.

Gorostiza, Pau, Matthew Volgraf, Rika Numano, et al.. (2007). Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor. Proceedings of the National Academy of Sciences. 104(26). 10865–10870. 149 indexed citations

20.

Cohen, Bruce E., Arnd Pralle, Xiao-Jie Yao, et al.. (2005). A fluorescent probe designed for studying protein conformational change. Proceedings of the National Academy of Sciences. 102(4). 965–970. 100 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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