Eva‐Maria Mandelkow

37.8k total citations · 12 hit papers
196 papers, 23.0k citations indexed

About

Eva‐Maria Mandelkow is a scholar working on Physiology, Molecular Biology and Cell Biology. According to data from OpenAlex, Eva‐Maria Mandelkow has authored 196 papers receiving a total of 23.0k indexed citations (citations by other indexed papers that have themselves been cited), including 126 papers in Physiology, 94 papers in Molecular Biology and 84 papers in Cell Biology. Recurrent topics in Eva‐Maria Mandelkow's work include Alzheimer's disease research and treatments (126 papers), Microtubule and mitosis dynamics (71 papers) and Neuroscience and Neuropharmacology Research (39 papers). Eva‐Maria Mandelkow is often cited by papers focused on Alzheimer's disease research and treatments (126 papers), Microtubule and mitosis dynamics (71 papers) and Neuroscience and Neuropharmacology Research (39 papers). Eva‐Maria Mandelkow collaborates with scholars based in Germany, United States and United Kingdom. Eva‐Maria Mandelkow's co-authors include Eckhard Mandelkow�, Jacek Biernat, Gerard Drewes, Martin von Bergen�, N. Gustke, Anja Schneider, Bernhard Trinczek, Andreas Ebneth, Hans Zempel and Yipeng Wang and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Eva‐Maria Mandelkow

196 papers receiving 22.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease

2001 782 citations Eva‐Maria Mandelkow et al. profile →
Tau in Alzheimer's disease

1998 781 citations Eva‐Maria Mandelkow et al. profile →
MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption

1997 712 citations Gerard Drewes, Andreas Ebneth et al. profile →
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease

2001 635 citations Jacek Biernat, Eva‐Maria Mandelkow et al. Journal of Biological Chemistry profile →
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

1993 633 citations Jacek Biernat, N. Gustke et al. profile →
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

2012 630 citations Eva‐Maria Mandelkow profile →
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads

1994 626 citations Eva‐Maria Mandelkow et al. profile →
Aβ Oligomers Cause Localized Ca ²⁺ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

2010 531 citations Hans Zempel, Edda Thies et al. profile →
Domains of tau Protein and Interactions with Microtubules

1994 530 citations N. Gustke, Bernhard Trinczek et al. profile →
The release and trans-synaptic transmission of Tau via exosomes

2017 505 citations Katharina Tepper, Eckhard Mandelkow� et al. Molecular Neurodegeneration profile →
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

2009 488 citations Yipeng Wang, Marta Martínez‐Vicente et al. profile →
Neuronal activity regulates extracellular tau in vivo

2014 422 citations Kaoru Yamada, Jerrah K. Holth et al. The Journal of Experimental Medicine profile →

Peers

Countries citing papers authored by Eva‐Maria Mandelkow

Since Specialization

Citations

This map shows the geographic impact of Eva‐Maria Mandelkow's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eva‐Maria Mandelkow with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eva‐Maria Mandelkow more than expected).

Fields of papers citing papers by Eva‐Maria Mandelkow

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eva‐Maria Mandelkow. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eva‐Maria Mandelkow. The network helps show where Eva‐Maria Mandelkow may publish in the future.

Co-authorship network of co-authors of Eva‐Maria Mandelkow

This figure shows the co-authorship network connecting the top 25 collaborators of Eva‐Maria Mandelkow. A scholar is included among the top collaborators of Eva‐Maria Mandelkow based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eva‐Maria Mandelkow. Eva‐Maria Mandelkow is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study 2022 ·Molecular Neurobiology ·Heike Endepols, Marta Anglada‐Huguet, Eckhard Mandelkow�, (unknown), Philipp Krapf, Boris D. Zlatopolskiy, Bernd Neumaier, Eva‐Maria Mandelkow, Alexander Drzezga	12
2	RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease 2021 ·Cell Death and Disease ·(unknown), Anna Sancho‐Balsells, (unknown), (unknown), (unknown), (unknown), Marta Anglada‐Huguet, (unknown), Eva‐Maria Mandelkow, Jordi Alberch, Albert Giralt, Cristina Malagelada	31
3	A mechanistic model of tau amyloid aggregation based on direct observation of oligomers 2015 ·Nature Communications ·Sarah L. Shammas, Gonzalo Garcia, Satish Kumar, Magnus Kjærgaard, Mathew H. Horrocks, (unknown), Eva‐Maria Mandelkow, Tuomas P. J. Knowles, Eckhard Mandelkow�, David Klenerman	163
4	Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia 2015 ·Molecular Neurodegeneration ·Hans Zempel, Eva‐Maria Mandelkow	65
5	Oligomer Formation of Tau Protein Hyperphosphorylated in Cells 2014 ·Journal of Biological Chemistry ·Katharina Tepper, Jacek Biernat, Satish Kumar, Susanne Wegmann, Thomas Timm, (unknown), Lars Redecke, Eva‐Maria Mandelkow, Daniel J. Müller, Eckhard Mandelkow�	123
6	Neuronal activity regulates extracellular tau in vivo breakdown → 2014 ·The Journal of Experimental Medicine ·Kaoru Yamada, Jerrah K. Holth, Fan Liao, Floy R. Stewart, Thomas E. Mahan, Hong Jiang, John R. Cirrito, Tirth K. Patel, Katja Hochgräfe, Eva‐Maria Mandelkow, David M. Holtzman	422
7	Emerging modes of PINK1 signaling: another task for MARK2 2014 ·Frontiers in Molecular Neuroscience ·Dorthe Matenia, Eva‐Maria Mandelkow	9
8	Conformations of Microtubule-Associated Protein Tau Mapped by Fluorescence Resonance Energy Transfer 2012 ·Methods in molecular biology ·Sadasivam Jeganathan�, Subashchandrabose Chinnathambi, Eva‐Maria Mandelkow, Eckhard Mandelkow�	14
9	Microtubule Affinity Regulating Kinase Activity in Living Neurons Was Examined by a Genetically Encoded Fluorescence Resonance Energy Transfer/Fluorescence Lifetime Imaging-based Biosensor 2011 ·Journal of Biological Chemistry ·Thomas Timm, Jens Peter von Kries, Xiaoyu Li, Hans Zempel, Eckhard Mandelkow�, Eva‐Maria Mandelkow, (unknown), (unknown)	34
10	Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation 2010 ·Autophagy ·Yipeng Wang, Marta Martínez‐Vicente, Ulrike Krüger, Susmita Kaushik, Esther Wong, Eva‐Maria Mandelkow, Ana María Cuervo, (unknown), (unknown)	76
11	Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment 2010 ·Neurobiology of Aging ·Sarika Garg, Thomas Timm, Eva‐Maria Mandelkow, (unknown), (unknown), Yipeng Wang	90
12	Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation 2008 ·Journal of Biological Chemistry ·Sadasivam Jeganathan�, Antje Hascher, Subashchandrabose Chinnathambi, Jacek Biernat, Eva‐Maria Mandelkow, Eckhard Mandelkow�	205
13	Structure of the Catalytic and Ubiquitin-Associated Domains of the Protein Kinase MARK/Par-1 2006 ·Structure ·S. Panneerselvam, Alexander Marx, Eva‐Maria Mandelkow, Eckhard Mandelkow�	67
14	MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons 2004 ·The Journal of Cell Biology ·Eva‐Maria Mandelkow, Edda Thies, Bernhard Trinczek, Jacek Biernat, (unknown)	186
15	Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells 1999 ·Cell Motility and the Cytoskeleton ·Andreas Ebneth, Gerard Drewes, Eva‐Maria Mandelkow, (unknown), (unknown)	127
16	Phosphorylation of Microtubule-associated Proteins MAP2 and MAP4 by the Protein Kinase p110mark 1996 ·Journal of Biological Chemistry ·Susanne Illenberger, Gerard Drewes, Bernhard Trinczek, Jacek Biernat, Helmut E. Meyer, J.B. Olmsted, Eva‐Maria Mandelkow, Eckhard Mandelkow�	158
17	RNA stimulates aggregation of microtubule‐associated protein tau into Alzheimer‐like paired helical filaments 1996 ·FEBS Letters ·(unknown), Peter Friedhoff, Jacek Biernat, Eckhard Mandelkow�, Eva‐Maria Mandelkow, (unknown), (unknown)	427
18	The cytoskeleton : 45. Colloquium der Gesellschaft für Biologische Chemie, 14.-16. April 1994 in Mosbach/Baden 1995 ·Springer eBooks ·(unknown), B. M. Jockusch, Eva‐Maria Mandelkow, Klaus Weber	1
19	Tau domains, phosphorylation, and interactions with microtubules 1995 ·Neurobiology of Aging ·Eva‐Maria Mandelkow, Jacek Biernat, Gerard Drewes, N. Gustke, Bernhard Trinczek	248
20	Microtubule oscillations 1992 ·Cell Motility and the Cytoskeleton ·Eva‐Maria Mandelkow, (unknown), Eckhard Mandelkow�	42

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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