Aaron M. Hosios

5.2k total citations · 3 hit papers
26 papers, 2.9k citations indexed

About

Aaron M. Hosios is a scholar working on Molecular Biology, Cancer Research and Physiology. According to data from OpenAlex, Aaron M. Hosios has authored 26 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Molecular Biology, 15 papers in Cancer Research and 5 papers in Physiology. Recurrent topics in Aaron M. Hosios's work include Cancer, Hypoxia, and Metabolism (15 papers), Metabolism, Diabetes, and Cancer (6 papers) and Metabolomics and Mass Spectrometry Studies (5 papers). Aaron M. Hosios is often cited by papers focused on Cancer, Hypoxia, and Metabolism (15 papers), Metabolism, Diabetes, and Cancer (6 papers) and Metabolomics and Mass Spectrometry Studies (5 papers). Aaron M. Hosios collaborates with scholars based in United States, South Africa and Switzerland. Aaron M. Hosios's co-authors include Matthew G. Vander Heiden, Elizaveta Freinkman, Lucas B. Sullivan, Dan Y. Gui, Laura V. Danai, Scott R. Manalis, Vivian Hecht, Marc O. Johnson, Matthew L. Steinhauser and Jeffrey C. Rathmell and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Aaron M. Hosios

26 papers receiving 2.9k citations

Hit Papers

Supporting Aspartate Biosynthesis Is an Essential Functio... 2015 2026 2018 2022 2015 2016 2016 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells
    2015 779 citations Lucas B. Sullivan, Dan Y. Gui et al. Cell profile →
  2. Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells
    2016 470 citations Aaron M. Hosios, Vivian Hecht et al. Developmental Cell profile →
  3. Tissue of origin dictates branched-chain amino acid metabolism in mutantKras-driven cancers
    2016 438 citations Jared R. Mayers, Margaret E. Torrence et al. profile →

Peers

Aaron M. Hosios
Jessica Sudderth United States
Paulo A. Gameiro United States
Ashley Solmonson United States
Laura V. Danai United States
Katherine Mattaini United States
Steven J. Kridel United States
Erin Currie United Kingdom
Sumin Kang United States
Brian F. Clem United States
Taro Hitosugi United States
Jessica Sudderth United States
Aaron M. Hosios
Citations per year, relative to Aaron M. Hosios Aaron M. Hosios (= 1×) peers Jessica Sudderth

Countries citing papers authored by Aaron M. Hosios

Since Specialization
Citations

This map shows the geographic impact of Aaron M. Hosios's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Aaron M. Hosios with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Aaron M. Hosios more than expected).

Fields of papers citing papers by Aaron M. Hosios

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Aaron M. Hosios. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Aaron M. Hosios. The network helps show where Aaron M. Hosios may publish in the future.

Co-authorship network of co-authors of Aaron M. Hosios

This figure shows the co-authorship network connecting the top 25 collaborators of Aaron M. Hosios. A scholar is included among the top collaborators of Aaron M. Hosios based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Aaron M. Hosios. Aaron M. Hosios is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Merrick, Karl A., Yi Wen Kong, Anita Izrael-Tomasevic, et al.. (2024). An RNA damage response network mediates the lethality of 5-FU in colorectal cancer. Cell Reports Medicine. 5(10). 101778–101778. 11 indexed citations
2.
Li, Zhaoqi, Brian W. Ji, Purushottam D. Dixit, et al.. (2022). Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Nature Metabolism. 4(6). 711–723. 46 indexed citations
3.
Yuskaitis, Christopher J., Michael R. MacArthur, Sarah J. Mitchell, et al.. (2022). The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth. Cell Reports. 39(7). 110824–110824. 8 indexed citations
4.
Hosios, Aaron M., Margaret E. Torrence, Ting C. Zhao, et al.. (2022). Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex. iScience. 25(11). 105458–105458. 3 indexed citations
5.
Hosios, Aaron M., et al.. (2022). mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species. Nature Metabolism. 4(12). 1792–1811. 29 indexed citations
6.
Luengo, Alba, Keene L. Abbott, Shawn M. Davidson, et al.. (2019). Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer. Nature Communications. 10(1). 5604–5604. 53 indexed citations
7.
Hosios, Aaron M., Zhaoqi Li, Evan C. Lien, & Matthew G. Vander Heiden. (2018). Preparation of Lipid-Stripped Serum for the Study of Lipid Metabolism in Cell Culture. BIO-PROTOCOL. 8(11). e2876–e2876. 14 indexed citations
8.
Sullivan, Lucas B., Alba Luengo, Laura V. Danai, et al.. (2018). Aspartate is an endogenous metabolic limitation for tumour growth. Nature Cell Biology. 20(7). 782–788. 243 indexed citations
9.
Hosios, Aaron M. & Matthew G. Vander Heiden. (2018). The redox requirements of proliferating mammalian cells. Journal of Biological Chemistry. 293(20). 7490–7498. 104 indexed citations
10.
Hosios, Aaron M. & Brendan D. Manning. (2018). Lysosomal catch-and-release controls mTORC1. Nature Cell Biology. 20(9). 996–997. 3 indexed citations
11.
Dexter, Joseph P., Patrick S. Ward, Tathagata Dasgupta, et al.. (2018). Lack of evidence for substrate channeling or flux between wildtype and mutant isocitrate dehydrogenase to produce the oncometabolite 2-hydroxyglutarate. Journal of Biological Chemistry. 293(52). 20051–20061. 13 indexed citations
12.
Mayers, Jared R., Margaret E. Torrence, Laura V. Danai, et al.. (2016). Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers. PMC. 34 indexed citations
13.
Hosios, Aaron M., Vivian Hecht, Laura V. Danai, et al.. (2016). Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells. Developmental Cell. 36(5). 540–549. 470 indexed citations breakdown →
14.
Hecht, Vivian, Lucas B. Sullivan, Robert Kimmerling, et al.. (2016). Biophysical changes reduce energetic demand in growth factor–deprived lymphocytes. The Journal of Cell Biology. 212(4). 439–447. 19 indexed citations
15.
Gui, Dan Y., Lucas B. Sullivan, Alba Luengo, et al.. (2016). Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin. Cell Metabolism. 24(5). 716–727. 224 indexed citations
16.
Hosios, Aaron M., Brian P. Fiske, Dan Y. Gui, & Matthew G. Vander Heiden. (2015). Lack of Evidence for PKM2 Protein Kinase Activity. Molecular Cell. 59(5). 850–857. 89 indexed citations
17.
Sullivan, Lucas B., et al.. (2015). Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells. Cell. 162(3). 552–563. 779 indexed citations breakdown →
18.
Son, Sung Min, Mark M. Stevens, Hui Xiao Chao, et al.. (2015). Cooperative nutrient accumulation sustains growth of mammalian cells. Scientific Reports. 5(1). 17401–17401. 12 indexed citations
19.
Hosios, Aaron M. & Matthew G. Vander Heiden. (2014). Acetate metabolism in cancer cells. Cancer & Metabolism. 2(1). 27–27. 33 indexed citations
20.
Reaves, Marshall Louis, et al.. (2013). Pyrimidine homeostasis is accomplished by directed overflow metabolism. Nature. 500(7461). 237–241. 90 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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