Caroline A. Lewis

13.1k total citations · 7 hit papers
63 papers, 7.7k citations indexed

About

Caroline A. Lewis is a scholar working on Molecular Biology, Cancer Research and Surgery. According to data from OpenAlex, Caroline A. Lewis has authored 63 papers receiving a total of 7.7k indexed citations (citations by other indexed papers that have themselves been cited), including 49 papers in Molecular Biology, 25 papers in Cancer Research and 11 papers in Surgery. Recurrent topics in Caroline A. Lewis's work include Cancer, Hypoxia, and Metabolism (19 papers), Mitochondrial Function and Pathology (10 papers) and RNA modifications and cancer (10 papers). Caroline A. Lewis is often cited by papers focused on Cancer, Hypoxia, and Metabolism (19 papers), Mitochondrial Function and Pathology (10 papers) and RNA modifications and cancer (10 papers). Caroline A. Lewis collaborates with scholars based in United States, United Kingdom and Germany. Caroline A. Lewis's co-authors include Matthew G. Vander Heiden, David M. Sabatini, Sze Ham Chan, Dan Y. Gui, Tenzin Kunchok, Monther Abu-Remaileh, Elizaveta Freinkman, Laura V. Danai, Alexander Muir and Almut Schulze and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Caroline A. Lewis

63 papers receiving 7.6k citations

Hit Papers

Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Con... 2014 2026 2018 2022 2014 2021 2014 2017 2019 100 200 300 400 500
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
    2014 525 citations Karim Bensaad, Caroline A. Lewis et al. Cell Reports profile →
  2. Metabolomics in cancer research and emerging applications in clinical oncology
    2021 457 citations Daniel R. Schmidt, Rutulkumar Patel et al. CA A Cancer Journal for Clinicians profile →
  3. Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells
    2014 438 citations Caroline A. Lewis, Seth J. Parker et al. Molecular Cell profile →
  4. Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase
    2017 372 citations Monther Abu-Remaileh, Elizaveta Freinkman et al. profile →
  5. Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
    2019 368 citations Mark R. Sullivan, Laura V. Danai et al. eLife profile →
  6. Increased demand for NAD+ relative to ATP drives aerobic glycolysis
    2020 351 citations Alba Luengo, Zhaoqi Li et al. Molecular Cell profile →
  7. APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia
    2021 197 citations Grzegorz Sienski, Nora Kory et al. Science Translational Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Caroline A. Lewis United States 39 5.2k 3.1k 969 792 735 63 7.7k
Kıvanç Birsoy United States 37 6.7k 1.3× 3.1k 1.0× 1.5k 1.6× 1.1k 1.3× 596 0.8× 73 9.9k
Jeffrey P. MacKeigan United States 32 4.4k 0.9× 1.4k 0.4× 678 0.7× 969 1.2× 505 0.7× 62 6.5k
Jie Zhou China 42 2.9k 0.6× 2.2k 0.7× 616 0.6× 784 1.0× 377 0.5× 104 5.0k
Jurre J. Kamphorst United States 27 5.1k 1.0× 3.3k 1.0× 567 0.6× 1.2k 1.5× 525 0.7× 37 7.7k
Rodrigue Rossignol France 44 5.5k 1.1× 1.6k 0.5× 1.3k 1.4× 440 0.6× 309 0.4× 110 7.9k
George Poulogiannis United Kingdom 28 3.8k 0.7× 2.1k 0.7× 429 0.4× 1.0k 1.3× 319 0.4× 46 5.8k
Lydia W.S. Finley United States 37 4.4k 0.9× 2.0k 0.6× 1.3k 1.3× 763 1.0× 265 0.4× 48 6.9k
Nathalie M. Mazure France 39 5.5k 1.1× 4.1k 1.3× 659 0.7× 1.0k 1.3× 263 0.4× 87 8.4k
Mary Selak United States 33 4.4k 0.9× 3.1k 1.0× 948 1.0× 703 0.9× 277 0.4× 55 7.4k
Yun‐Sil Lee South Korea 44 5.6k 1.1× 2.8k 0.9× 673 0.7× 989 1.2× 212 0.3× 174 8.4k

Countries citing papers authored by Caroline A. Lewis

Since Specialization
Citations

This map shows the geographic impact of Caroline A. Lewis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Caroline A. Lewis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Caroline A. Lewis more than expected).

Fields of papers citing papers by Caroline A. Lewis

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Caroline A. Lewis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Caroline A. Lewis. The network helps show where Caroline A. Lewis may publish in the future.

Co-authorship network of co-authors of Caroline A. Lewis

This figure shows the co-authorship network connecting the top 25 collaborators of Caroline A. Lewis. A scholar is included among the top collaborators of Caroline A. Lewis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Caroline A. Lewis. Caroline A. Lewis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Pena, Izabella A., Ju Shi, Sarah Chang, et al.. (2025). SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation. Nature Communications. 16(1). 978–978. 4 indexed citations
2.
3.
Godbole, Adwait Anand, Sneha Gopalan, Caroline A. Lewis, et al.. (2023). S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress. eLife. 12. 8 indexed citations
4.
Cangelosi, Andrew L., Anna M. Puszynska, Justin M. Roberts, et al.. (2022). Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine. Science. 377(6601). 47–56. 49 indexed citations
5.
Mana, Miyeko, Constantine N. Tzouanas, Shinya Imada, et al.. (2021). High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity. Cell Reports. 35(10). 109212–109212. 127 indexed citations
6.
Spinelli, Jessica B., Paul C. Rosen, Hans‐Georg Sprenger, et al.. (2021). Fumarate is a terminal electron acceptor in the mammalian electron transport chain. Science. 374(6572). 1227–1237. 145 indexed citations
7.
Lee, Min-Sik, Unmesh Jadhav, Shariq Madha, et al.. (2021). Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1. Proceedings of the National Academy of Sciences. 118(10). 41 indexed citations
8.
Schmidt, Daniel R., Rutulkumar Patel, David G. Kirsch, et al.. (2021). Metabolomics in cancer research and emerging applications in clinical oncology. CA A Cancer Journal for Clinicians. 71(4). 333–358. 457 indexed citations breakdown →
9.
Adelmann, Charles H., Brandon Chen, Kendall J. Condon, et al.. (2020). MFSD12 mediates the import of cysteine into melanosomes and lysosomes. Nature. 588(7839). 699–704. 62 indexed citations
10.
Sullivan, Mark R., Caroline A. Lewis, & Alexander Muir. (2019). Isolation and Quantification of Metabolite Levels in Murine Tumor Interstitial Fluid by LC/MS. BIO-PROTOCOL. 9(22). e3427–e3427. 7 indexed citations
11.
Sullivan, Mark R., Laura V. Danai, Caroline A. Lewis, et al.. (2019). Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability. eLife. 8. 368 indexed citations breakdown →
12.
Luengo, Alba, Keene L. Abbott, Shawn M. Davidson, et al.. (2019). Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer. Nature Communications. 10(1). 5604–5604. 53 indexed citations
13.
Li, Leanne, Sheng Rong Ng, Caterina I. Colón, et al.. (2019). Identification of DHODH as a therapeutic target in small cell lung cancer. Science Translational Medicine. 11(517). 103 indexed citations
14.
Bayraktar, Erol C., Lou Baudrier, Caroline A. Lewis, et al.. (2018). MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo. Proceedings of the National Academy of Sciences. 116(1). 303–312. 73 indexed citations
15.
Alkan, H. Furkan, Alba Luengo, Corina T. Madreiter‐Sokolowski, et al.. (2018). Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting. Cell Metabolism. 28(5). 706–720.e6. 131 indexed citations
16.
17.
Lewis, Caroline A., Seth J. Parker, Brian P. Fiske, et al.. (2014). Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells. Molecular Cell. 55(2). 253–263. 438 indexed citations breakdown →
18.
Lewis, Caroline A., Philip Doran, & Kay Ohlendieck. (2011). Proteomic Analysis of Dystrophic Muscle. Methods in molecular biology. 798. 357–369. 14 indexed citations
19.
Lewis, Caroline A., B Griffiths, Cláudio R. Santos, Mario Pende, & Almut Schulze. (2010). Genetic ablation of S6-kinase does not prevent processing of SREBP1. Advances in Enzyme Regulation. 51(1). 280–290. 9 indexed citations
20.
Gray, Gary R., et al.. (2003). Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development. Journal of Microbiological Methods. 56(2). 221–230. 22 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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