Sze Ham Chan

5.3k citations

22 papers · 2.8k indexed · 2 hit papers · h-index 17

Impact in

Cancer Research top 2%
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
Physiology top 1%
- Calcium signaling and nucleotide metabolism

Papers in

Physiology 3
- Calcium signaling and nucleotide metabolism 3
Cell Biology 7
- Cellular transport and secretion 4

Co-authors: David M. Sabatini Caroline A. Lewis Monther Abu-Remaileh Tenzin Kunchok Elizaveta Freinkman Gregory A. Wyant Nouf N. Laqtom Mitch McVey
Journals: Science (4 papers)Nature (4 papers)Proceedings of the National Academy of Sciences (3 papers)Nature Communications (2 papers)Science Advances (2 papers)
Partner nations: United States Germany Sweden

In The Last Decade

Sze Ham Chan

22 papers receiving 2.8k citations

Hit Papers

align trajectories log scale

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability 2019 · 368 citations

Peers

Countries citing papers authored by Sze Ham Chan

Since Specialization

Citations

This map shows the geographic impact of Sze Ham Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sze Ham Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sze Ham Chan more than expected).

Fields of papers citing papers by Sze Ham Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sze Ham Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sze Ham Chan. The network helps show where Sze Ham Chan may publish in the future.

Co-authors

The 25 scholars most cited alongside Sze Ham Chan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sze Ham Chan Line = papers co-authored together Sze Ham Chan links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Immune cell activation produces locally scrambled foci of plasma membrane lipids Faraday Discussions ·Daryna Sputay, Milka Doktorova, Sze Ham Chan, Elaine Guo, Hongyin Wang, Joseph H. Lorent, Ilya Levental, Kandice R. Levental	2025	1
2	MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes Nature Cell Biology ·Katharina E. J. Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort‐Tranchepain, Nouf N. Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Säftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Daμμe	2024	6
3	Coupling of protein condensates to ordered lipid domains determines functional membrane organization Science Advances ·Hongyin Wang, Sze Ham Chan, Simli Dey, Ivan Castello-Serrano, Michael K. Rosen, Jonathon A. Ditlev, Kandice R. Levental, Ilya Levental	2023	70
4	Rab3 mediates a pathway for endocytic sorting and plasma membrane recycling of ordered microdomains Proceedings of the National Academy of Sciences ·Barbara Diaz‐Rohrer, Ivan Castello-Serrano, Sze Ham Chan, Hongyin Wang, Carolyn R. Shurer, Kandice R. Levental, Ilya Levental	2023	16
5	Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine Science ·Andrew L. Cangelosi, Anna M. Puszynska, Justin M. Roberts, Andrea Armani, Thao P. Nguyen, Jessica B. Spinelli, Tenzin Kunchok, Brianna Wang, Sze Ham Chan, Caroline A. Lewis, William C. Comb, George W. Bell, Aharon Helman, David M. Sabatini	2022	49
6	CLN3 is required for the clearance of glycerophosphodiesters from lysosomes Nature ·Nouf N. Laqtom, Wentao Dong, Uche N. Medoh, Andrew L. Cangelosi, Vimisha Dharamdasani, Sze Ham Chan, Tenzin Kunchok, Caroline A. Lewis, Ivonne Heinze, Rachel Tang, Christian Grimm, An Dang, Forbes D. Porter, Alessandro Ori‬‬, David M. Sabatini, Monther Abu-Remaileh	2022	65
7	Dihydroxyacetone phosphate signals glucose availability to mTORC1 Nature Metabolism ·Jose M. Orozco, Patrycja A. Krawczyk, Sonia M. Scaria, Andrew L. Cangelosi, Sze Ham Chan, Tenzin Kunchok, Caroline A. Lewis, David M. Sabatini	2020	167
8	MFSD12 mediates the import of cysteine into melanosomes and lysosomes Nature ·Charles H. Adelmann, Anna K. Traunbauer, Brandon Chen, Kendall J. Condon, Sze Ham Chan, Tenzin Kunchok, Caroline A. Lewis, David M. Sabatini	2020	62
9	MCART1/SLC25A51 is required for mitochondrial NAD transport Science Advances ·Nora Kory, Jelmi uit de Bos, Sanne van der Rijt, Nevena Jankovic, Miriam A. Güra, Nicholas L. Arp, Izabella A. Pena, Gyan Prakash, Sze Ham Chan, Tenzin Kunchok, Caroline A. Lewis, David M. Sabatini	2020	130
10	Initiation-specific alleles of the Cdc45 helicase-activating protein PLoS ONE ·Ramón Yamil Ríos-Morales, Sze Ham Chan, Stephen P. Bell	2019	4
11	Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer Nature Communications ·Alba Luengo, Keene L. Abbott, Shawn M. Davidson, Aaron M. Hosios, Brandon Faubert, Sze Ham Chan, Elizaveta Freinkman, Lauren G. Zacharias, Thomas P. Mathews, Clary B. Clish, Ralph J. DeBerardinis, Caroline A. Lewis, Matthew G. Vander Heiden	2019	53
12	Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability eLife ·Mark R. Sullivan, Laura V. Danai, Caroline A. Lewis, Sze Ham Chan, Dan Y. Gui, Tenzin Kunchok, Emily A. Dennstedt, Matthew G. Vander Heiden, Alexander Muir Hit paper breakdown →	2019	368
13	m6A modification of a 3′ UTR site reduces RME1 mRNA levels to promote meiosis Nature Communications ·G. Guy Bushkin, David Pincus, Jeffrey T. Morgan, Kris Richardson, Caroline A. Lewis, Sze Ham Chan, David P. Bartel, Gerald R. Fink	2019	52
14	Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death Nature ·Javier García‐Bermúdez, Lou Baudrier, Erol C. Bayraktar, Yihui Shen, Konnor La, Rohiverth Guarecuco, Burcu Yücel, Danilo Fiore, Bernardo Tavora, Elizaveta Freinkman, Sze Ham Chan, Caroline A. Lewis, Wei Min, Giorgio Inghirami, David M. Sabatini, Kıvanç Birsoy	2019	315
15	6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels Cell chemical biology ·Haoxin Li, Maria Ericsson, Bokang Rabasha, Bogdan Budnik, Sze Ham Chan, Elizaveta Freinkman, Caroline A. Lewis, John G. Doench, Bridget K. Wagner, Levi A. Garraway, Stuart L. Schreiber	2019	22
16	MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo Proceedings of the National Academy of Sciences ·Erol C. Bayraktar, Lou Baudrier, Ceren Özerdem, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Andrew L. Cangelosi, David M. Sabatini, Kıvanç Birsoy, Walter W. Chen	2018	73
17	Histidine catabolism is a major determinant of methotrexate sensitivity Nature ·Naama Kanarek, Heather R. Keys, Jason R. Cantor, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Elizaveta Freinkman, Lawrence D. Schweitzer, David M. Sabatini	2018	226
18	NUFIP1 is a ribosome receptor for starvation-induced ribophagy Science ·Gregory A. Wyant, Monther Abu-Remaileh, Evgeni M. Frenkel, Nouf N. Laqtom, Vimisha Dharamdasani, Caroline A. Lewis, Sze Ham Chan, Ivonne Heinze, Alessandro Ori‬‬, David M. Sabatini	2018	264
19	Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes Science ·Monther Abu-Remaileh, Gregory A. Wyant, Choah Kim, Nouf N. Laqtom, Maria Abbasi, Sze Ham Chan, Elizaveta Freinkman, David M. Sabatini Hit paper breakdown →	2017	457
20	Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila PLoS Genetics ·Sze Ham Chan, Alder Yu, Mitch McVey	2010	193

About Sze Ham Chan

Sze Ham Chan is a scholar working on Physiology, Cell Biology, Clinical Biochemistry, Cancer Research and Molecular Biology, having authored 22 papers that have together received 2.8k indexed citations. Recurring topics across this work include RNA modifications and cancer (4 papers), Cellular transport and secretion (4 papers), Lipid Membrane Structure and Behavior (3 papers), Epigenetics and DNA Methylation (3 papers), Metabolomics and Mass Spectrometry Studies (3 papers), Cancer, Hypoxia, and Metabolism (3 papers), Calcium signaling and nucleotide metabolism (3 papers) and Autophagy in Disease and Therapy (3 papers). The work is most often cited by research in Cancer Research (728 citations), Physiology (211 citations), Biochemistry (212 citations), Molecular Biology (1.8k citations) and Cell Biology (379 citations). Sze Ham Chan has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include David M. Sabatini, Caroline A. Lewis, Monther Abu-Remaileh, Tenzin Kunchok, Elizaveta Freinkman, Gregory A. Wyant, Nouf N. Laqtom, Mitch McVey, Alder Yu and Choah Kim. Their work appears in journals such as Science, Nature, Proceedings of the National Academy of Sciences, Nature Communications and Science Advances.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact