Joshua D. Rabinowitz

71.5k total citations · 30 hit papers
328 papers, 49.1k citations indexed

About

Joshua D. Rabinowitz is a scholar working on Molecular Biology, Cancer Research and Physiology. According to data from OpenAlex, Joshua D. Rabinowitz has authored 328 papers receiving a total of 49.1k indexed citations (citations by other indexed papers that have themselves been cited), including 215 papers in Molecular Biology, 68 papers in Cancer Research and 45 papers in Physiology. Recurrent topics in Joshua D. Rabinowitz's work include Cancer, Hypoxia, and Metabolism (62 papers), Metabolomics and Mass Spectrometry Studies (57 papers) and Microbial Metabolic Engineering and Bioproduction (49 papers). Joshua D. Rabinowitz is often cited by papers focused on Cancer, Hypoxia, and Metabolism (62 papers), Metabolomics and Mass Spectrometry Studies (57 papers) and Microbial Metabolic Engineering and Bioproduction (49 papers). Joshua D. Rabinowitz collaborates with scholars based in United States, Germany and China. Joshua D. Rabinowitz's co-authors include Eileen White, Wenyun Lu, Bryson D. Bennett, Gregory S. Ducker, Craig B. Thompson, Jing Fan, Elizabeth Kimball, Jurre J. Kamphorst, Cholsoon Jang and Li Chen and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Joshua D. Rabinowitz

318 papers receiving 48.6k citations

Hit Papers

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate 2008 2026 2014 2020 2009 2010 2010 2009 2016 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    2009 3.1k citations Bryson D. Bennett, Joshua D. Rabinowitz et al. Nature profile →
  2. Autophagy and Metabolism
    2010 1.6k citations Joshua D. Rabinowitz, Eileen White Science profile →
  3. The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
    2010 1.5k citations Bryson D. Bennett, Justin R. Cross et al. profile →
  4. Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
    2009 1.4k citations Bryson D. Bennett, Joshua D. Rabinowitz et al. Nature Chemical Biology profile →
  5. One-Carbon Metabolism in Health and Disease
    2016 1.4k citations Gregory S. Ducker, Joshua D. Rabinowitz profile →
  6. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
    2013 1.3k citations Cosimo Commisso, Shawn M. Davidson et al. Nature profile →
  7. Glucose feeds the TCA cycle via circulating lactate
    2017 1.2k citations Jonathan M. Ghergurovich, Cholsoon Jang et al. Nature profile →
  8. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
    2011 1.1k citations Jessie Yanxiang Guo, Robin Mathew et al. profile →
  9. The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
    2014 1.1k citations Joshua D. Rabinowitz et al. profile →
  10. Mitochondria and Cancer
    2016 957 citations Joshua D. Rabinowitz, Eileen White et al. profile →
  11. Quantitative flux analysis reveals folate-dependent NADPH production
    2014 856 citations Jing Fan, Jiangbin Ye et al. Nature profile →
  12. Lactate: the ugly duckling of energy metabolism
    2020 667 citations Joshua D. Rabinowitz et al. profile →
  13. Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
    2015 644 citations Jurre J. Kamphorst, Michel Nofal et al. Cancer Research profile →
  14. Metabolomics and Isotope Tracing
    2018 573 citations Cholsoon Jang, Joshua D. Rabinowitz et al. profile →
  15. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
    2013 560 citations Jurre J. Kamphorst, Justin R. Cross et al. Proceedings of the National Academy of Sciences profile →
  16. Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
    2008 513 citations Bryson D. Bennett, Xiao‐Jiang Feng et al. profile →
  17. Evidence for an alternative glycolytic pathway in rapidly proliferating cells
    2010 509 citations Matthew G. Vander Heiden, Jason W. Locasale et al. Europe PMC (PubMed Central) profile →
  18. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
    2017 481 citations Joshua D. Rabinowitz et al. profile →
  19. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
    2013 471 citations Jessie Yanxiang Guo, Robin Mathew et al. profile →
  20. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids
    2018 444 citations Cholsoon Jang, Wenyun Lu et al. profile →
  21. Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
    2014 437 citations Jessie Yanxiang Guo, Joshua D. Rabinowitz et al. Cancer Discovery profile →
  22. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
    2020 388 citations Cholsoon Jang, Xianfeng Zeng et al. Nature profile →
  23. Quantitative Analysis of NAD Synthesis-Breakdown Fluxes
    2018 370 citations Eileen White, Marie E. Migaud et al. profile →
  24. Comprehensive quantification of fuel use by the failing and nonfailing human heart
    2020 367 citations Cholsoon Jang, Joshua D. Rabinowitz et al. Science profile →
  25. Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids
    2018 342 citations Cholsoon Jang, Eileen White et al. profile →
  26. Metabolite Measurement: Pitfalls to Avoid and Practices to Follow
    2017 325 citations Wenyun Lu, Joshua D. Rabinowitz et al. profile →
  27. NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism
    2019 282 citations Michael P. Morley, Zoltàn Arany et al. profile →
  28. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance
    2020 259 citations Hsin‐Jung Li, Joshua D. Rabinowitz et al. profile →
  29. The pentose phosphate pathway in health and disease
    2023 252 citations Tara TeSlaa, Jing Fan et al. profile →
  30. Lactate homeostasis is maintained through regulation of glycolysis and lipolysis
    2025 19 citations Wenyun Lu, Tara TeSlaa et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Joshua D. Rabinowitz United States 110 30.9k 12.3k 7.0k 5.2k 4.9k 328 49.1k
Navdeep S. Chandel United States 106 33.7k 1.1× 15.9k 1.3× 4.8k 0.7× 6.9k 1.3× 7.3k 1.5× 303 57.5k
John M. Asara United States 90 24.3k 0.8× 11.3k 0.9× 4.8k 0.7× 3.5k 0.7× 3.5k 0.7× 293 36.4k
Matthew G. Vander Heiden United States 91 37.2k 1.2× 26.0k 2.1× 3.7k 0.5× 5.5k 1.1× 4.1k 0.8× 225 54.5k
Clary B. Clish United States 91 23.3k 0.8× 8.7k 0.7× 4.5k 0.6× 4.0k 0.8× 8.6k 1.7× 384 40.1k
Ralph J. DeBerardinis United States 81 28.3k 0.9× 19.6k 1.6× 3.1k 0.4× 4.2k 0.8× 2.9k 0.6× 233 42.6k
Toren Finkel United States 97 30.3k 1.0× 5.2k 0.4× 7.8k 1.1× 6.5k 1.2× 11.4k 2.3× 211 55.4k
Vamsi K. Mootha United States 87 51.6k 1.7× 11.6k 0.9× 5.6k 0.8× 7.3k 1.4× 10.7k 2.2× 199 72.9k
Chi V. Dang United States 100 38.9k 1.3× 24.2k 2.0× 2.6k 0.4× 5.2k 1.0× 3.2k 0.7× 310 53.3k
Xiaodong Wang China 88 48.8k 1.6× 7.5k 0.6× 8.5k 1.2× 11.4k 2.2× 3.0k 0.6× 320 63.8k
Christian von Mering Switzerland 68 45.6k 1.5× 7.5k 0.6× 3.4k 0.5× 5.6k 1.1× 3.0k 0.6× 134 69.7k

Countries citing papers authored by Joshua D. Rabinowitz

Since Specialization
Citations

This map shows the geographic impact of Joshua D. Rabinowitz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joshua D. Rabinowitz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joshua D. Rabinowitz more than expected).

Fields of papers citing papers by Joshua D. Rabinowitz

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joshua D. Rabinowitz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joshua D. Rabinowitz. The network helps show where Joshua D. Rabinowitz may publish in the future.

Co-authorship network of co-authors of Joshua D. Rabinowitz

This figure shows the co-authorship network connecting the top 25 collaborators of Joshua D. Rabinowitz. A scholar is included among the top collaborators of Joshua D. Rabinowitz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joshua D. Rabinowitz. Joshua D. Rabinowitz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Blanc‐Betes, Elena, N. Gomez‐Casanovas, Wendy H. Yang, et al.. (2023). Accelerating the development of a sustainable bioenergy portfolio through stable isotopes. GCB Bioenergy. 15(7). 840–866. 7 indexed citations
2.
Wang, Lin, Xi Xing, Xianfeng Zeng, et al.. (2022). Spatially resolved isotope tracing reveals tissue metabolic activity. Nature Methods. 19(2). 223–230. 104 indexed citations
3.
Jankowski, Connor S.R. & Joshua D. Rabinowitz. (2022). Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate. Cancer Research. 82(19). 3486–3498. 19 indexed citations
4.
Lindell, Robert B., Donglan Zhang, Jenny Bush, et al.. (2022). Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation. Shock. 57(6). 191–199. 12 indexed citations
5.
Luongo, Timothy S., Mu‐Jie Lu, Marc Niere, et al.. (2020). SLC25A51 is a mammalian mitochondrial NAD+ transporter. Nature. 588(7836). 174–179. 205 indexed citations
6.
Guan, Dongyin, Ying Xiong, Yang Xiao, et al.. (2020). The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 369(6509). 1388–1394. 111 indexed citations
7.
Ghergurovich, Jonathan M., Mark Esposito, Zihong Chen, et al.. (2020). Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras–Driven Tumor Growth or Metastasis. Cancer Research. 80(18). 3820–3829. 36 indexed citations
8.
Li, Albert M., Gregory S. Ducker, Yang Li, et al.. (2020). Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research. 18(4). 599–611. 58 indexed citations
9.
Park, Junyoung O., Lukas B. Tanner, Monica Wei, et al.. (2019). Near-equilibrium glycolysis supports metabolic homeostasis and energy yield. Nature Chemical Biology. 15(10). 1001–1008. 51 indexed citations
10.
Rajeshkumar, N.V., Shinichi Yabuuchi, Shweta Pai, et al.. (2017). Treatment of Pancreatic Cancer Patient–Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clinical Cancer Research. 23(18). 5639–5647. 74 indexed citations
11.
Rowe, Glenn C., Steven Yang, Jian Li, et al.. (2017). PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circulation Research. 121(12). 1370–1378. 37 indexed citations
12.
Rajeshkumar, N.V., Prasanta Dutta, Shinichi Yabuuchi, et al.. (2015). Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function. Cancer Research. 75(16). 3355–3364. 119 indexed citations
13.
Kamphorst, Jurre J., Michel Nofal, Cosimo Commisso, et al.. (2015). Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein. Cancer Research. 75(3). 544–553. 644 indexed citations breakdown →
14.
Ye, Jiangbin, Jing Fan, Sriram Venneti, et al.. (2014). Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia. Cancer Discovery. 4(12). 1406–1417. 344 indexed citations
15.
Kamphorst, Jurre J., Justin R. Cross, Jing Fan, et al.. (2013). Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences. 110(22). 8882–8887. 560 indexed citations breakdown →
16.
Heiden, Matthew G. Vander, Jason W. Locasale, Kenneth D. Swanson, et al.. (2010). Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells. Science. 329(5998). 1492–1499. 31 indexed citations
17.
Heiden, Matthew G. Vander, Jason W. Locasale, Kenneth D. Swanson, et al.. (2010). Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Europe PMC (PubMed Central). 509 indexed citations breakdown →
18.
Goodarzi, Hani, Bryson D. Bennett, Sasan Amini, et al.. (2010). Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli. Molecular Systems Biology. 6(1). 378–378. 130 indexed citations
19.
Seltzer, Meghan J., Bryson D. Bennett, Avadhut D. Joshi, et al.. (2010). Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1. Cancer Research. 70(22). 8981–8987. 410 indexed citations
20.
Rabinowitz, Joshua D., Jennifer J. Hsiao, Evan R. Kantrowitz, et al.. (2008). Dissecting Enzyme Regulation by Multiple Allosteric Effectors: Nucleotide Regulation of Aspartate Transcarbamoylase. Biochemistry. 47(21). 5881–5888. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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