Ralph J. DeBerardinis

731 total papers · 75.1k total citations
233 papers, 42.2k citations indexed

About

Ralph J. DeBerardinis is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Ralph J. DeBerardinis has authored 233 papers receiving a total of 42.2k indexed citations (citations by other indexed papers that have themselves been cited), including 164 papers in Molecular Biology, 118 papers in Cancer Research and 26 papers in Oncology. Recurrent topics in Ralph J. DeBerardinis's work include Cancer, Hypoxia, and Metabolism (113 papers), Mitochondrial Function and Pathology (46 papers) and Metabolism, Diabetes, and Cancer (30 papers). Ralph J. DeBerardinis is often cited by papers focused on Cancer, Hypoxia, and Metabolism (113 papers), Mitochondrial Function and Pathology (46 papers) and Metabolism, Diabetes, and Cancer (30 papers). Ralph J. DeBerardinis collaborates with scholars based in United States, Canada and China. Ralph J. DeBerardinis's co-authors include Craig B. Thompson, Navdeep S. Chandel, Julian J. Lum, Georgia Hatzivassiliou, Matthew G. Vander Heiden, Ashley Solmonson, Brandon Faubert, Tzuling Cheng, Lindsey K. Boroughs and Christopher T. Hensley and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Ralph J. DeBerardinis

225 papers receiving 41.8k citations

Hit Papers

The Biology of Cancer: Me... 1996 2026 2006 2016 2008 2016 2007 2020 2008 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation benchmark for papers published in the same subfield and year, or reaches the top citation threshold in at least one of its specific research topics.

  1. The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
    2008 3.1k citations Ralph J. DeBerardinis, Julian J. Lum et al. Cell Metabolism profile →
  2. Fundamentals of cancer metabolism
    2016 2.1k citations Ralph J. DeBerardinis, Navdeep S. Chandel Science Advances profile →
  3. Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
    2007 2.0k citations Ralph J. DeBerardinis, Anthony Mancuso et al. Proceedings of the National Academy of Sciences profile →
  4. Metabolic reprogramming and cancer progression
    2020 1.6k citations Brandon Faubert, Ashley Solmonson et al. Science profile →
  5. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
    2008 1.5k citations David R. Wise, Ralph J. DeBerardinis et al. Proceedings of the National Academy of Sciences profile →
  6. Understanding the Intersections between Metabolism and Cancer Biology
    2017 1.5k citations Matthew G. Vander Heiden, Ralph J. DeBerardinis Cell profile →
  7. Metabolic pathways promoting cancer cell survival and growth
    2015 1.1k citations Lindsey K. Boroughs, Ralph J. DeBerardinis Nature Cell Biology profile →
  8. Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
    2009 1.0k citations Ralph J. DeBerardinis, Tzuling Cheng Oncogene profile →
  9. Reductive carboxylation supports growth in tumour cells with defective mitochondria
    2011 1.0k citations Andrew R. Mullen, William W. Wheaton et al. Nature profile →
  10. Glutamine and cancer: cell biology, physiology, and clinical opportunities
    2013 981 citations Christopher T. Hensley, Ajla Wasti et al. Journal of Clinical Investigation profile →
  11. Toll-like receptor–induced changes in glycolytic metabolism regulate dendritic cell activation
    2010 971 citations Connie M. Krawczyk, Thomas Holowka et al. Blood profile →
  12. Oxidative stress inhibits distant metastasis by human melanoma cells
    2015 926 citations Elena Piskounova, Michalis Agathocleous et al. Nature profile →
  13. Brick by brick: metabolism and tumor cell growth
    2008 812 citations Ralph J. DeBerardinis, Dara Ditsworth et al. Current Opinion in Genetics & Development profile →
  14. High Frequency Retrotransposition in Cultured Mammalian Cells
    1996 809 citations John V. Moran, Susan E. Holmes et al. Cell profile →
  15. The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
    2010 807 citations Fatih Kocabaş, Junke Zheng et al. Cell stem cell profile →
  16. Systemic Treatment with the Antidiabetic Drug Metformin Selectively Impairs p53-Deficient Tumor Cell Growth
    2007 755 citations Monica Buzzai, Russell G. Jones et al. Cancer Research profile →
  17. AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
    2012 730 citations Brandon Faubert, Gino Boily et al. Cell Metabolism profile →
  18. A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals
    2013 681 citations Yiguang Wang, Ke‐Jin Zhou et al. Nature Materials profile →
  19. Autophagy in metazoans: cell survival in the land of plenty
    2005 635 citations Julian J. Lum, Ralph J. DeBerardinis et al. Nature Reviews Molecular Cell Biology profile →
  20. Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?
    2012 625 citations Ralph J. DeBerardinis, Craig B. Thompson Cell profile →
  21. 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas
    2012 616 citations Changho Choi, Sandeep Ganji et al. Nature Medicine profile →
  22. Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research
    2011 580 citations John Kurhanewicz, Daniel B. Vigneron et al. Neoplasia profile →
  23. We need to talk about the Warburg effect
    2020 578 citations Ralph J. DeBerardinis, Navdeep S. Chandel Nature Metabolism profile →
  24. Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases
    2014 574 citations Tomoyuki Mashimo, Kumar Pichumani et al. Cell profile →
  25. NRF2 regulates serine biosynthesis in non–small cell lung cancer
    2015 556 citations Gina M. DeNicola, Pei-Hsuan Chen et al. Nature Genetics profile →
  26. Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
    2014 512 citations Chendong Yang, Bookyung Ko et al. Molecular Cell profile →
  27. Reductive carboxylation supports redox homeostasis during anchorage-independent growth
    2016 432 citations Lei Jiang, Alexander A. Shestov et al. Nature profile →
  28. Mechanisms and Implications of Metabolic Heterogeneity in Cancer
    2019 400 citations Jiyeon Kim, Ralph J. DeBerardinis Cell Metabolism profile →
  29. Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
    2017 390 citations Michalis Agathocleous, Corbin E. Meacham et al. Nature profile →
  30. Mechanical regulation of glycolysis via cytoskeleton architecture
    2020 381 citations Jin Suk Park, Christoph J. Burckhardt et al. Nature profile →
  31. Metabolic heterogeneity confers differences in melanoma metastatic potential
    2019 346 citations Alpaslan Tasdogan, Brandon Faubert et al. Nature profile →
  32. Lipoic acid metabolism and mitochondrial redox regulation
    2017 325 citations Ashley Solmonson, Ralph J. DeBerardinis Journal of Biological Chemistry profile →
  33. Severely polarized extracellular acidity around tumour cells
    2024 71 citations Qiang Feng, Tongyi Huang et al. Nature Biomedical Engineering profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Ralph J. DeBerardinis 28.2k 19.5k 5.2k 4.2k 3.1k 233 42.2k
Matthew G. Vander Heiden 37.0k 1.3× 25.9k 1.3× 7.3k 1.4× 5.5k 1.3× 3.7k 1.2× 225 54.2k
Chi V. Dang 38.8k 1.4× 24.1k 1.2× 9.4k 1.8× 5.2k 1.2× 2.6k 0.8× 307 53.1k
Jacques Pouysségur 29.0k 1.0× 12.3k 0.6× 6.1k 1.2× 3.7k 0.9× 1.7k 0.6× 369 42.0k
John M. Asara 24.2k 0.9× 11.3k 0.6× 5.2k 1.0× 3.5k 0.8× 4.8k 1.5× 290 36.2k
Joshua D. Rabinowitz 30.7k 1.1× 12.3k 0.6× 4.4k 0.8× 5.2k 1.2× 7.0k 2.2× 327 48.7k
Amato J. Giaccia 23.1k 0.8× 17.3k 0.9× 10.7k 2.1× 4.6k 1.1× 2.3k 0.7× 350 40.2k
Christopher W. Pugh 19.2k 0.7× 21.8k 1.1× 3.2k 0.6× 2.4k 0.6× 1.4k 0.4× 145 32.5k
Peng Huang 18.0k 0.6× 7.4k 0.4× 5.9k 1.1× 2.2k 0.5× 2.2k 0.7× 329 31.3k
Jason W. Locasale 16.1k 0.6× 9.1k 0.5× 3.9k 0.8× 4.1k 1.0× 2.0k 0.6× 182 24.6k
William G. Kaelin 35.6k 1.3× 22.5k 1.2× 14.8k 2.9× 3.1k 0.7× 2.4k 0.8× 246 50.1k

Countries citing papers authored by Ralph J. DeBerardinis

Since Specialization
Citations

This map shows the geographic impact of Ralph J. DeBerardinis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ralph J. DeBerardinis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ralph J. DeBerardinis more than expected).

Fields of papers citing papers by Ralph J. DeBerardinis

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ralph J. DeBerardinis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ralph J. DeBerardinis. The network helps show where Ralph J. DeBerardinis may publish in the future.

Co-authorship network of co-authors of Ralph J. DeBerardinis

This figure shows the co-authorship network connecting the top 25 collaborators of Ralph J. DeBerardinis. A scholar is included among the top collaborators of Ralph J. DeBerardinis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ralph J. DeBerardinis. Ralph J. DeBerardinis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Loading papers...

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Cajo J. F. ter Braak Breakdown of academic impact, for papers by Jimy Dudhia Breakdown of academic impact, for papers by David Tse Breakdown of academic impact, for papers by John W. Olney Breakdown of academic impact, for papers by Gideon Dreyfuss Breakdown of academic impact, for papers by Peter T. Lansbury Breakdown of academic impact, for papers by D. Blöch Breakdown of academic impact, for papers by Donald E. Canfield
Rankless by CCL
2026