Jeffrey C. Rathmell

40.0k total citations · 15 hit papers
202 papers, 25.8k citations indexed

About

Jeffrey C. Rathmell is a scholar working on Immunology, Molecular Biology and Cancer Research. According to data from OpenAlex, Jeffrey C. Rathmell has authored 202 papers receiving a total of 25.8k indexed citations (citations by other indexed papers that have themselves been cited), including 120 papers in Immunology, 89 papers in Molecular Biology and 53 papers in Cancer Research. Recurrent topics in Jeffrey C. Rathmell's work include Immune Cell Function and Interaction (78 papers), Cancer, Hypoxia, and Metabolism (44 papers) and T-cell and B-cell Immunology (42 papers). Jeffrey C. Rathmell is often cited by papers focused on Immune Cell Function and Interaction (78 papers), Cancer, Hypoxia, and Metabolism (44 papers) and T-cell and B-cell Immunology (42 papers). Jeffrey C. Rathmell collaborates with scholars based in United States, Germany and France. Jeffrey C. Rathmell's co-authors include Craig B. Thompson, Nancie J. MacIver, Ryan D. Michalek, Valerie A. Gerriets, Sarah R. Jacobs, Andrew N. Macintyre, Jessica A. Wofford, Heather L. Wieman, David R. Plas and Amanda Nichols and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Jeffrey C. Rathmell

194 papers receiving 25.5k citations

Hit Papers

Cutting Edge: Distinct Gl... 2002 2026 2010 2018 2011 2002 2015 2013 2014 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
    2011 1.6k citations Ryan D. Michalek, Valerie A. Gerriets et al. The Journal of Immunology profile →
  2. The CD28 Signaling Pathway Regulates Glucose Metabolism
    2002 1.1k citations Kenneth A. Frauwirth, James L. Riley et al. Immunity profile →
  3. Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
    2015 1.1k citations Andrew N. Macintyre, Xiaojing Liu et al. profile →
  4. Metabolic Regulation of T Lymphocytes
    2013 970 citations Ryan D. Michalek, Jeffrey C. Rathmell et al. profile →
  5. The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
    2014 887 citations Andrew N. Macintyre, Valerie A. Gerriets et al. profile →
  6. Targeting Metabolism to Improve the Tumor Microenvironment for Cancer Immunotherapy
    2020 683 citations Kelsey Voss, Jeffrey C. Rathmell et al. profile →
  7. Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways
    2008 658 citations Jeffrey C. Rathmell et al. The Journal of Immunology profile →
  8. MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation
    2017 479 citations Melissa M. Wolf, Jeffrey C. Rathmell et al. profile →
  9. Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells
    2016 470 citations Jeffrey C. Rathmell et al. profile →
  10. Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells
    2014 418 citations Amanda Nichols, Jeffrey C. Rathmell et al. The Journal of Immunology profile →
  11. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
    2016 409 citations Valerie A. Gerriets, Peter J. Siska et al. profile →
  12. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models
    2018 379 citations Jeffrey C. Rathmell et al. profile →
  13. Metabolic programming and immune suppression in the tumor microenvironment
    2023 323 citations Emily N. Arner, Jeffrey C. Rathmell profile →
  14. High-fat diet–induced colonocyte dysfunction escalates microbiota-derived trimethylamine N -oxide
    2021 217 citations Jeffrey C. Rathmell et al. profile →
  15. Cancer cell metabolism and antitumour immunity
    2024 133 citations Jeffrey C. Rathmell et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jeffrey C. Rathmell United States 83 13.0k 11.1k 6.5k 5.6k 2.5k 202 25.8k
Manolis Pasparakis Germany 84 12.3k 0.9× 13.4k 1.2× 5.8k 0.9× 4.3k 0.8× 3.3k 1.3× 193 26.6k
Erika L. Pearce United States 47 14.2k 1.1× 8.5k 0.8× 4.4k 0.7× 4.9k 0.9× 2.8k 1.1× 83 23.1k
Russell G. Jones Canada 57 8.1k 0.6× 11.2k 1.0× 5.6k 0.9× 3.8k 0.7× 2.3k 0.9× 112 20.4k
Akihiko Yoshimura Japan 82 11.3k 0.9× 10.6k 1.0× 3.1k 0.5× 7.0k 1.2× 2.8k 1.1× 349 27.4k
George Kollias Greece 89 10.9k 0.8× 12.1k 1.1× 3.5k 0.5× 5.6k 1.0× 2.1k 0.9× 306 30.3k
Michael J. Lenardo United States 89 17.6k 1.3× 14.9k 1.3× 5.1k 0.8× 6.5k 1.1× 5.2k 2.1× 244 34.1k
Klaus‐Michael Debatin Germany 85 9.1k 0.7× 20.6k 1.9× 5.1k 0.8× 6.5k 1.2× 3.8k 1.5× 521 33.1k
Avi Ashkenazi United States 80 9.3k 0.7× 23.8k 2.1× 5.7k 0.9× 6.0k 1.1× 3.7k 1.5× 200 33.2k
Pamela S. Ohashi Canada 93 23.0k 1.8× 10.1k 0.9× 3.8k 0.6× 7.2k 1.3× 2.2k 0.9× 317 33.6k
Jacques J. Peschon United States 63 11.5k 0.9× 9.1k 0.8× 3.2k 0.5× 5.9k 1.0× 2.3k 0.9× 94 24.8k

Countries citing papers authored by Jeffrey C. Rathmell

Since Specialization
Citations

This map shows the geographic impact of Jeffrey C. Rathmell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeffrey C. Rathmell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeffrey C. Rathmell more than expected).

Fields of papers citing papers by Jeffrey C. Rathmell

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeffrey C. Rathmell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeffrey C. Rathmell. The network helps show where Jeffrey C. Rathmell may publish in the future.

Co-authorship network of co-authors of Jeffrey C. Rathmell

This figure shows the co-authorship network connecting the top 25 collaborators of Jeffrey C. Rathmell. A scholar is included among the top collaborators of Jeffrey C. Rathmell based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jeffrey C. Rathmell. Jeffrey C. Rathmell is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Jennings, Erin Q., W. Kimryn Rathmell, & Jeffrey C. Rathmell. (2025). Targeted Metabolomic Methods for 13 C Stable Isotope Labeling with Uniformly Labeled Glucose and Glutamine Using Liquid Chromatography–Tandem Mass Spectrometry (LC–MS/MS). Journal of Proteome Research. 24(12). 6328–6337.
2.
3.
Rathmell, Jeffrey C., et al.. (2025). Metabolic and stress response adaptations in T cells to fever and physiological heat. Trends in Immunology. 46(3). 195–205. 3 indexed citations
4.
Bacigalupa, Zachary A., Emily N. Arner, Melissa M. Wolf, et al.. (2024). HIF-2α expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma. Journal of Clinical Investigation. 134(12). 7 indexed citations
5.
Voss, Kelsey, Todd Bartkowiak, Heather H. Pua, et al.. (2024). Peripheral T Cell Development and Immunophenotyping of Twins with Heterozygous FOXN1 Mutations. ImmunoHorizons. 8(7). 492–499.
6.
Hinshaw, Dominique C., Gloria A. Benavides, Brandon J. Metge, et al.. (2023). Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer. Cancer Immunology Research. 11(5). 687–702. 21 indexed citations
7.
Chaib, Mehdi, Emilie L. Fisher, Laura M. Sipe, et al.. (2023). Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer. Science Advances. 9(51). eadd3231–eadd3231. 8 indexed citations
8.
Melo, Paulo H., Annie R. Piñeros, Xiang Ye, et al.. (2021). Macrophage-Derived MicroRNA-21 Drives Overwhelming Glycolytic and Inflammatory Response during Sepsis via Repression of the PGE2/IL-10 Axis. The Journal of Immunology. 207(3). 902–912. 17 indexed citations
9.
Contreras, Diana C., Jacqueline Cephus, Nowrin U. Chowdhury, et al.. (2021). Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation. The Journal of Immunology. 206(6). 1127–1139. 17 indexed citations
10.
Hinshaw, Dominique C., Ann Hanna, Tshering Lama-Sherpa, et al.. (2021). Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages. Cancer Research. 81(21). 5425–5437. 83 indexed citations
11.
Beckermann, Kathryn E., Rachel A. Hongo, Xiang Ye, et al.. (2020). CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. JCI Insight. 5(16). 72 indexed citations
12.
Sinclair, Linda V., Andrew J.M. Howden, Alejandro J. Brenes, et al.. (2019). Antigen receptor control of methionine metabolism in T cells. eLife. 8. 161 indexed citations
13.
Greenplate, Allison R., Deon B. Doxie, Kirsten E. Diggins, et al.. (2018). Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types. Cancer Immunology Research. 7(1). 86–99. 21 indexed citations
14.
Arreola, Alexandra, C. Lance Cowey, Jonathan L. Coloff, Jeffrey C. Rathmell, & W. Kimryn Rathmell. (2014). HIF1α and HIF2α Exert Distinct Nutrient Preferences in Renal Cells. PLoS ONE. 9(5). e98705–e98705. 13 indexed citations
15.
Coloff, Jonathan L., Andrew N. Macintyre, Amanda Nichols, et al.. (2011). Akt-Dependent Glucose Metabolism Promotes Mcl-1 Synthesis to Maintain Cell Survival and Resistance to Bcl-2 Inhibition. Cancer Research. 71(15). 5204–5213. 108 indexed citations
16.
Michalek, Ryan D., Valerie A. Gerriets, Amanda Nichols, et al.. (2011). Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. Proceedings of the National Academy of Sciences. 108(45). 18348–18353. 169 indexed citations
17.
Ke, Hengning, Rebecca Harris, Jonathan L. Coloff, et al.. (2010). The c-Jun NH2-Terminal Kinase 2 Plays a Dominant Role in Human Epidermal Neoplasia. Cancer Research. 70(8). 3080–3088. 47 indexed citations
18.
Mason, Emily F., Yuxing Zhao, Pankuri Goraksha-Hicks, et al.. (2010). Aerobic Glycolysis Suppresses p53 Activity to Provide Selective Protection from Apoptosis upon Loss of Growth Signals or Inhibition of BCR-Abl. Cancer Research. 70(20). 8066–8076. 39 indexed citations
19.
Juntilla, Marisa M., Matthew Thomas, Daniel Northrup, et al.. (2009). Akt1 and Akt2 promote peripheral B-cell maturation and survival. Blood. 115(20). 4043–4050. 72 indexed citations
20.
Frauwirth, Kenneth A., James L. Riley, Marian H. Harris, et al.. (2002). The CD28 Signaling Pathway Regulates Glucose Metabolism. Immunity. 16(6). 769–777. 1134 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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