Thomas McDonagh

3.9k citations

28 papers · 3.1k indexed · 2 hit papers · h-index 18

Impact in

Geriatrics and Gerontology top 0.1%
- Sirtuins and Resveratrol in Medicine
Aging top 1%
- Genetics, Aging, and Longevity in Model Organisms

Papers in ⓘ

Molecular Biology 12
- Lipid Membrane Structure and Behavior 2
Geriatrics and Gerontology 9
- Sirtuins and Resveratrol in Medicine 9

Co-authors: Peter S. DiStefano (9 shared papers)Rory Curtis (6 shared papers)Jeffrey Hixon (5 shared papers)Andrew D. Napper (4 shared papers)Leonard Guarente (4 shared papers)Jonathan M. Solomon (1 shared paper)Michael W. McBurney (3 shared papers)Lei Xu (1 shared paper)
Journals: Journal of Biological Chemistry (6 papers)PLoS Biology (2 papers)Journal of Molecular Biology (2 papers)Journal of Medicinal Chemistry (2 papers)Journal of Virology (2 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

Thomas McDonagh

28 papers receiving 3.0k citations

Hit Papers

align trajectories log scale

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells 2005 · 585 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2005 PLoS Biology
2005 Journal of Biological Chemistry

Peers

Countries citing papers authored by Thomas McDonagh

Since Specialization

Citations

This map shows the geographic impact of Thomas McDonagh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas McDonagh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas McDonagh more than expected).

Fields of papers citing papers by Thomas McDonagh

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas McDonagh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas McDonagh. The network helps show where Thomas McDonagh may publish in the future.

Co-authors

The 25 scholars most cited alongside Thomas McDonagh, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas McDonagh Line = papers co-authored together Thomas McDonagh links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 28 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Substrate-specific Activation of Sirtuins by Resveratrol Journal of Biological Chemistry ·Matt Kaeberlein, Thomas McDonagh, Birgit Heltweg, Jeffrey Hixon, Eric A. Westman, Seth D. Caldwell, Andrew D. Napper, Rory Curtis, Peter S. DiStefano, Stanley Fields, Antonio Bedalov, Brian K. Kennedy Hit paper breakdown →	2005	603
2	Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells PLoS Biology ·Laura Bordone, Maria Carla Motta, Frédéric Picard, Ashley Robinson, Ulupi S. Jhala, Javier Apfeld, Thomas McDonagh, Madeleine E. Lemieux, Michael W. McBurney, Akos Szilvasi, Erin Easlon, Su-Ju Lin, Leonard Guarente Hit paper breakdown →	2005	585
3	Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1 Journal of Medicinal Chemistry ·Andrew D. Napper, Jeffrey Hixon, Thomas McDonagh, Kenneth Keavey, Jean‐François Pons, Juliet N. Barker, Wei Tsung Yau, Patricia Amouzegh, Adam Flegg, Estelle Hamelin, Russell J. Thomas, Michael J. Kates, Stephen P. Jones, Manuel A. Navia, Jeffrey O. Saunders, Peter S. DiStefano, Rory Curtis	2005	436
4	Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival following DNA Damage Molecular and Cellular Biology ·Jonathan M. Solomon, Rao Pasupuleti, Lei Xu, Thomas McDonagh, Rory Curtis, Peter S. DiStefano, L. Julie Huber	2005	401
5	Crystal Structure of the Wild-type von Willebrand Factor A1-Glycoprotein Ibα Complex Reveals Conformation Differences with a Complex Bearing von Willebrand Disease Mutations Journal of Biological Chemistry ·John J. Dumas, R. Anand Kumar, Thomas McDonagh, Francis Sullivan, Mark Stahl, W.S. Somers, Lidia Mosyak	2004	158
6	Autocatalytic Cleavage of ADAMTS-4 (Aggrecanase-1) Reveals Multiple Glycosaminoglycan-binding Sites Journal of Biological Chemistry ·Carl R. Flannery, Weilan Zeng, Chris Corcoran, Lisa A. Collins‐Racie, Priya Chockalingam, Tracy Hebert, Stewart A. Mackie, Thomas McDonagh, Tara K. Crawford, Kathy N. Tomkinson, Edward R. LaVallie, Elizabeth A. Morris	2002	123
7	Independent Folding and Ligand Specificity of the C2 Calciumdependent Lipid Binding Domain of Cytosolic Phospholipase A2 Journal of Biological Chemistry ·Eric A. Nalefski, Thomas McDonagh, W.S. Somers, Jasbir Seehra, Joseph J. Falke, James D. Clark	1998	110
8	Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A 2 1 1Edited by J. Karn Journal of Molecular Biology ·Guangyi Xu, Thomas McDonagh, Hsiang‐Ai Yu, Eric A. Nalefski, James D. Clark, Dale A. Cumming	1998	91
9	Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice Regulatory Peptides ·Kenneth Longo, Soratree Charoenthongtrakul, Derek J. Giuliana, Elizabeth Govek, Thomas McDonagh, Yong Qi, Peter S. DiStefano, Brad J. Geddes	2008	84
10	ADAMTS4 Cleaves at the Aggrecanase Site (Glu373-Ala374) and Secondarily at the Matrix Metalloproteinase Site (Asn341-Phe342) in the Aggrecan Interglobular Domain Journal of Biological Chemistry ·Jennifer Westling, Amanda Fosang, Karena Last, Vivian P. Thompson, Kathy N. Tomkinson, Tracy Hebert, Thomas McDonagh, Lisa A. Collins‐Racie, Edward R. LaVallie, Elizabeth A. Morris, John D. Sandy	2002	72
11	Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic ß Cells PLoS Biology ·Laura Bordone, Maria Carla Motta, Frédéric Picard, Ashley Robinson, Ulupi S. Jhala, Javier Apfeld, Thomas McDonagh, Madeleine E. Lemieux, Michael I. McBurney, Akos Szilvasi, Erin Easlon, Su-Ju Lin, Leonard Guarente	2006	68
12	Solution structure of recombinant human interleukin-6 1 1Edited by P. E. Wright Journal of Molecular Biology ·Guangyi Xu, Hsiang‐Ai Yu, Jin Hong, Mark Stahl, Thomas McDonagh, Lewis E. Kay, Dale A. Cumming	1997	60
13	SIRT1 Shows No Substrate Specificity in Vitro Journal of Biological Chemistry ·Gil Blander, Jerzy Olejnik, Edyta Krzymańska-Olejnik, Thomas McDonagh, Marcia C. Haigis, Michael B. Yaffe, Leonard Guarente	2005	58
14	Solution Structure of N-TRADD and Characterization of the Interaction of N-TRADD and C-TRAF2, a Key Step in the TNFR1 Signaling Pathway Molecular Cell ·Désirée H.H. Tsao, Thomas McDonagh, Jean-Baptiste Telliez, Sang Hsu, Karl Malakian, Guang-Yi Xu, Lih-Ling Lin	2000	50
15	Sirt1-Independent Mechanisms of the Putative Sirtuin Enzyme Activators SRT1720 and SRT2183 Future Medicinal Chemistry ·Julie L Huber, Michael W. McBurney, Peter S. DiStefano, Thomas McDonagh	2010	40
16	The 24-hour respiratory quotient predicts energy intake and changes in body mass American Journal of Physiology-Regulatory, Integrative and Comparative Physiology ·Kenneth Longo, Soratree Charoenthongtrakul, Derek J. Giuliana, Elizabeth Govek, Thomas McDonagh, Peter S. DiStefano, Brad J. Geddes	2009	38
17	Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin Methods ·Thomas McDonagh, Jeffrey Hixon, Peter S. DiStefano, Rory Curtis, Andrew D. Napper	2005	26
18	Pharmacologic Inhibition of Ghrelin Receptor Signaling Is Insulin Sparing and Promotes Insulin Sensitivity Journal of Pharmacology and Experimental Therapeutics ·Kenneth Longo, Elizabeth Govek, Anna Nolan, Thomas McDonagh, Soratree Charoenthongtrakul, Derek J. Giuliana, Kristen Morgan, Jeffrey Hixon, Chaoseng Zhou, Bruce Kelder, John J. Kopchick, Jeffrey O. Saunders, Manuel A. Navia, Rory Curtis, Peter S. DiStefano, Brad J. Geddes	2011	22
19	Assessing infant and maternal readiness for newborn discharge Current Opinion in Pediatrics ·Jing Ling, Casidhe-Nicole Bethancourt, Thomas McDonagh	2017	17
20	Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic b Cells Laura Bordone, Maria Carla Motta, Frédéric Picard, Ulupi S. Jhala, Javier Apfeld, Thomas McDonagh, Madeleine E. Lemieux, Michael W. McBurney, Erin Easlon, Leonard Guarente	2006	16

About Thomas McDonagh

Thomas McDonagh is a scholar working on Molecular Biology, Geriatrics and Gerontology, Epidemiology, Physiology and Virology, having authored 28 papers that have together received 3.1k indexed citations. Recurring topics across this work include Sirtuins and Resveratrol in Medicine (9 papers), Autophagy in Disease and Therapy (5 papers), Adipose Tissue and Metabolism (4 papers), HIV Research and Treatment (3 papers), Regulation of Appetite and Obesity (3 papers), Pancreatic function and diabetes (2 papers), Lipid Membrane Structure and Behavior (2 papers) and Cell Adhesion Molecules Research (2 papers). The work is most often cited by research in Geriatrics and Gerontology (1.5k citations), Aging (180 citations), Physiology (342 citations), Physiology (981 citations) and Endocrine and Autonomic Systems (170 citations). Thomas McDonagh has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Peter S. DiStefano, Rory Curtis, Jeffrey Hixon, Andrew D. Napper, Leonard Guarente, Jonathan M. Solomon, Michael W. McBurney, Lei Xu, L. Julie Huber and Ulupi S. Jhala. Their work appears in journals such as Journal of Biological Chemistry, PLoS Biology, Journal of Molecular Biology, Journal of Medicinal Chemistry and Journal of Virology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact