Lewis E. Kay

41.5k citations

369 papers · 33.4k indexed · 9 hit papers · h-index 96

Impact in

Spectroscopy top 0.01%
- Advanced NMR Techniques and Applications
- Mass Spectrometry Techniques and Applications
Biophysics top 0.02%
- Electron Spin Resonance Studies

Papers in

Biophysics 60
- Electron Spin Resonance Studies 59
Spectroscopy 142
- Advanced NMR Techniques and Applications 110
- Molecular spectroscopy and chirality 28

Co-authors: Julie D. Forman‐Kay Vitali Tugarinov Pramodh Vallurupalli Anthony Mittermaier Dmitry M. Korzhnev Kevin H. Gardner D. Flemming Hansen D.R. Muhandiram
Journals: Journal of the American Chemical Society (81 papers)Journal of Biomolecular NMR (56 papers)Proceedings of the National Academy of Sciences (56 papers)Journal of Molecular Biology (22 papers)Biochemistry (21 papers)
Partner nations: Canada United States United Kingdom

In The Last Decade

Lewis E. Kay

365 papers receiving 33.1k citations

Hit Papers

9 papers align trajectories log scale

Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation 2017 · 376 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2017 Proceedings of the National Academy of Sciences
2014 Nature
2006 Science
2005 Nature
1997 Journal of the American Chemical Society
1994 Journal of Biomolecular NMR
1994 Biochemistry
1992 Biochemistry
1990 Journal of the American Chemical Society

Peers

Countries citing papers authored by Lewis E. Kay

Since Specialization

Citations

This map shows the geographic impact of Lewis E. Kay's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lewis E. Kay with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lewis E. Kay more than expected).

Fields of papers citing papers by Lewis E. Kay

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lewis E. Kay. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lewis E. Kay. The network helps show where Lewis E. Kay may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Lewis E. Kay, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lewis E. Kay Line = papers co-authored together Lewis E. Kay links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Exploiting conformational dynamics to modulate the function of designed proteins Proceedings of the National Academy of Sciences ·Enrico Rennella, Danny D. Sahtoe, David Baker, Lewis E. Kay	2023	15
2	Opening of a cryptic pocket in β-lactamase increases penicillinase activity Proceedings of the National Academy of Sciences ·Catherine R. Knoverek, Upasana L. Mallimadugula, Sukrit Singh, Enrico Rennella, Thomas E. Frederick, Tairan Yuwen, 光和福田, Lewis E. Kay, Gregory R. Bowman	2021	22
3	An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR Proceedings of the National Academy of Sciences ·Siavash Vahidi, Zev A. Ripstein, 岡本裕嗣, Enrico Rennella, Alfred L. Goldberg, Anthony Mittermaier, John L. Rubinstein, Lewis E. Kay	2020	44
4	Hsp70 biases the folding pathways of client proteins Proceedings of the National Academy of Sciences ·Ashok Sekhar, Rina Rosenzweig, Guillaume Bouvignies, Lewis E. Kay	2016	79
5	Unfolding the mechanism of the AAA+ unfoldase VAT by a combined cryo-EM, solution NMR study Proceedings of the National Academy of Sciences ·Rui Huang, Zev A. Ripstein, Rafał Augustyniak, Michał Łaźniewski, Krzysztof Ginalski, Lewis E. Kay, John L. Rubinstein	2016	43
6	Mapping the conformation of a client protein through the Hsp70 functional cycle Proceedings of the National Academy of Sciences ·Ashok Sekhar, Rina Rosenzweig, Guillaume Bouvignies, Lewis E. Kay	2015	70
7	Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site Proceedings of the National Academy of Sciences ·Mohammad T. Mazhab‐Jafari, Christopher B. Marshall, Matthew J. Smith, Geneviève M. C. Gasmi-Seabrook, Peter B. Stathopulos, Fuyuhiko Inagaki, Lewis E. Kay, Benjamin G. Neel, Mitsuhiko Ikura	2015	167
8	Defining a length scale for millisecond-timescale protein conformational exchange Proceedings of the National Academy of Sciences ·Ashok Sekhar, Pramodh Vallurupalli, Lewis E. Kay	2013	26
9	Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction Science ·Rina Rosenzweig, Shoeib Moradi, Arash Zarrine‐Afsar, John R. Glover, Lewis E. Kay	2013	210
10	Architecture of the high mobility group nucleosomal protein 2-nucleosome complex as revealed by methyl-based NMR Proceedings of the National Academy of Sciences ·Hidenori Kato, Hugo van Ingen, Bing‐Rui Zhou, Hanqiao Feng, Michael Bustin, Lewis E. Kay, Yawen Bai	2011	141
11	Dynamic Regulation of Archaeal Proteasome Gate Opening As Studied by TROSY NMR Science ·Tomasz L. Religa, Remco Sprangers, Lewis E. Kay	2010	182
12	A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution Science ·Dmitry M. Korzhnev, Tomasz L. Religa, Toshio Mihashi, Alan R. Fersht, Lewis E. Kay	2010	244
13	Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor Proceedings of the National Academy of Sciences ·Tanja Mittag, Stephen Orlicky, Wing‐Yiu Choy, Xiaojing Tang, Hong Lin, Frank Sicheri, Lewis E. Kay, Mike Tyers, Julie D. Forman‐Kay	2008	284
14	A solution NMR study showing that active site ligands and nucleotides directly perturb the allosteric equilibrium in aspartate transcarbamoylase Proceedings of the National Academy of Sciences ·Algirdas Vėlyvis, Ying R. Yang, H. K. Schachman, Lewis E. Kay	2007	76
15	Probing Supramolecular Structure from Measurement of Methyl ¹ H− ¹³ C Residual Dipolar Couplings Journal of the American Chemical Society ·Remco Sprangers, Lewis E. Kay	2007	34
16	Φ-Value analysis of a three-state protein folding pathway by NMR relaxation dispersion spectroscopy Proceedings of the National Academy of Sciences ·Philipp Neudecker, Arash Zarrine‐Afsar, Alan R. Davidson, Lewis E. Kay	2007	39
17	Variable Control of Ets-1 DNA Binding by Multiple Phosphates in an Unstructured Region Science ·Miles A. Pufall, Gregory M. Lee, Mary L. Nelson, Hyun-Seo Kang, Algirdas Vėlyvis, Lewis E. Kay, Lawrence P. McIntosh, Barbara J. Graves	2005	209
18	A New Spin Probe of Protein Dynamics: Nitrogen Relaxation in ¹⁵ N− ² H Amide Groups Journal of the American Chemical Society ·Matthew Altman-Suchocki, Óscar Millet, Lewis E. Kay, Nikolai R. Skrynnikov	2005	11
19	The integral membrane enzyme PagP alternates between two dynamically distinct states Proceedings of the National Academy of Sciences ·Peter M. Hwang, Russell E. Bishop, Lewis E. Kay	2004	84
20	Site-specific contributions to the pH dependence of protein stability Proceedings of the National Academy of Sciences ·Martin Tollinger, Karin A. Crowhurst, Lewis E. Kay, Julie D. Forman‐Kay	2003	76

About Lewis E. Kay

Lewis E. Kay is a scholar working on Biophysics, Spectroscopy, Molecular Biology, Nuclear and High Energy Physics and Materials Chemistry, having authored 369 papers that have together received 33.4k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (225 papers), Enzyme Structure and Function (116 papers), Advanced NMR Techniques and Applications (110 papers), Electron Spin Resonance Studies (59 papers), NMR spectroscopy and applications (50 papers), RNA and protein synthesis mechanisms (47 papers), Molecular spectroscopy and chirality (28 papers) and RNA Research and Splicing (23 papers). The work is most often cited by research in Spectroscopy (9.8k citations), Biophysics (2.7k citations), Molecular Biology (27.6k citations), Nuclear and High Energy Physics (2.8k citations) and Materials Chemistry (9.4k citations). Lewis E. Kay has collaborated with scholars based in Canada, United States and United Kingdom. Frequent co-authors include Julie D. Forman‐Kay, Vitali Tugarinov, Pramodh Vallurupalli, Anthony Mittermaier, Dmitry M. Korzhnev, Kevin H. Gardner, D. Flemming Hansen, D.R. Muhandiram, Remco Sprangers and Ashok Sekhar. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biomolecular NMR, Proceedings of the National Academy of Sciences, Journal of Molecular Biology and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact