Irene Caffa

3.6k total citations · 1 hit paper
54 papers, 2.0k citations indexed

About

Irene Caffa is a scholar working on Geriatrics and Gerontology, Molecular Biology and Oncology. According to data from OpenAlex, Irene Caffa has authored 54 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 23 papers in Geriatrics and Gerontology, 20 papers in Molecular Biology and 14 papers in Oncology. Recurrent topics in Irene Caffa's work include Sirtuins and Resveratrol in Medicine (18 papers), Calcium signaling and nucleotide metabolism (12 papers) and PARP inhibition in cancer therapy (9 papers). Irene Caffa is often cited by papers focused on Sirtuins and Resveratrol in Medicine (18 papers), Calcium signaling and nucleotide metabolism (12 papers) and PARP inhibition in cancer therapy (9 papers). Irene Caffa collaborates with scholars based in Italy, United States and Switzerland. Irene Caffa's co-authors include Alessio Nencioni, Valter D. Longo, Salvatore Cortellino, Michele Cea, Santina Bruzzone, Fiammetta Monacelli, Debora Soncini, Alberto Ballestrero, Giovanna Sociali and Alessia Grozio and has published in prestigious journals such as Journal of Biological Chemistry, Nature Communications and Journal of Clinical Oncology.

In The Last Decade

Irene Caffa

51 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Fasting and cancer: molecular mechanisms and clinical application

2018 355 citations Alessio Nencioni, Irene Caffa et al. Nature reviews. Cancer profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Irene Caffa Italy	23	718	539	494	443	364	54	2.0k
Yoon‐Jin Lee South Korea	19	826 1.2×	333 0.6×	395 0.8×	247 0.6×	233 0.6×	47	1.7k
Lisha Zhou China	19	1.4k 1.9×	437 0.8×	219 0.4×	396 0.9×	538 1.5×	47	2.2k
Yibo Wu China	17	1.1k 1.5×	321 0.6×	550 1.1×	177 0.4×	153 0.4×	40	2.0k
Attila Brunyánszki United States	18	822 1.1×	508 0.9×	348 0.7×	677 1.5×	78 0.2×	25	1.8k
Chih‐Chuan Liang China	25	1.4k 2.0×	615 1.1×	461 0.9×	146 0.3×	407 1.1×	100	2.7k
Bruna Pucci Italy	19	986 1.4×	264 0.5×	153 0.3×	461 1.0×	289 0.8×	26	1.9k
Asma Naqvi United States	21	990 1.4×	520 1.0×	537 1.1×	135 0.3×	198 0.5×	35	2.0k
Hyun‐Seok Kim South Korea	22	1.5k 2.0×	1.6k 2.9×	703 1.4×	486 1.1×	414 1.1×	76	3.4k
Eric Holle United States	15	1.1k 1.5×	536 1.0×	480 1.0×	181 0.4×	98 0.3×	18	1.9k
Jinling Hou United States	23	994 1.4×	385 0.7×	277 0.6×	192 0.4×	110 0.3×	28	1.7k

Countries citing papers authored by Irene Caffa

Since Specialization

Citations

This map shows the geographic impact of Irene Caffa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Irene Caffa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Irene Caffa more than expected).

Fields of papers citing papers by Irene Caffa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Irene Caffa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Irene Caffa. The network helps show where Irene Caffa may publish in the future.

Co-authorship network of co-authors of Irene Caffa

This figure shows the co-authorship network connecting the top 25 collaborators of Irene Caffa. A scholar is included among the top collaborators of Irene Caffa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Irene Caffa. Irene Caffa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

1.

Caffa, Irene, Tommaso Bonfiglio, Ana Guijarro, et al.. (2025). Prognostic Frailty-Based Determinants of Long-Term Mortality in Older Patients with Newly Diagnosed Multiple Myeloma. Cancers. 17(5). 789–789.

2.

Guijarro, Ana, Giulia Allavena, Livia Pisciotta, Alessio Nencioni, & Irene Caffa. (2025). Aging-Related Mechanisms Underlying Carcinogenesis: Therapeutic Opportunities. Aging and Disease.

3.

Tagliafico, Luca A., Małgorzata Tokarska-Schlattner, Tommaso Bonfiglio, et al.. (2024). Short‐term starvation activates AMPK and restores mitochondrial inorganic polyphosphate, but fails to reverse associated neuronal senescence. Aging Cell. 23(11). e14289–e14289. 4 indexed citations

4.

Caffa, Irene, et al.. (2024). Inhibitors of NAD+ Production in Cancer Treatment: State of the Art and Perspectives. International Journal of Molecular Sciences. 25(4). 2092–2092. 10 indexed citations

5.

Caffa, Irene, et al.. (2023). Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents. Pharmaceutics. 15(5). 1472–1472. 2 indexed citations

6.

Moreno‐Vargas, Antonio J., Ana T. Carmona, Aimable Nahimana, et al.. (2023). Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor activity on solid and haematological cancer. European Journal of Medicinal Chemistry. 250. 115170–115170. 7 indexed citations

7.

Piacente, Francesco, Melanie Walter, Irene Caffa, et al.. (2022). Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors. Pharmaceuticals. 15(7). 855–855. 12 indexed citations

8.

Becherini, Pamela, Irene Caffa, Francesco Piacente, et al.. (2021). SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice. SHILAP Revista de lepidopterología. 9(1). 6–6. 36 indexed citations

9.

Nencioni, Alessio, Irene Caffa, Salvatore Cortellino, & Valter D. Longo. (2018). Fasting and cancer: molecular mechanisms and clinical application. Nature reviews. Cancer. 18(11). 707–719. 355 indexed citations breakdown →

10.

Bello, Claudia, Jian‐Fei Bai, Consuelo Gajate, et al.. (2018). Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells. European Journal of Medicinal Chemistry. 150. 457–478. 6 indexed citations

11.

Piacente, Francesco, Irene Caffa, Silvia Ravera, et al.. (2017). Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair. Cancer Research. 77(14). 3857–3869. 83 indexed citations

12.

Carbone, Federico, Luca Liberale, Aldo Bonaventura, et al.. (2017). Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. Comprehensive physiology. 7(2). 603–621. 10 indexed citations

13.

Carbone, Federico, Luca Liberale, Aldo Bonaventura, et al.. (2017). Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin. Comprehensive physiology. 7(2). 603–621. 96 indexed citations

14.

Brown, David N., Irene Caffa, Gabriella Cirmena, et al.. (2016). Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer. Scientific Reports. 6(1). 19435–19435. 118 indexed citations

15.

Zoppoli, Gabriele, David N. Brown, Irene Caffa, et al.. (2016). Squalene epoxidase is a potential metabolic oncogene by amplification with clinical implications in breast carcinoma. Annals of Oncology. 27. iv68–iv68. 1 indexed citations

16.

Ammazzalorso, Alessandra, Irene Caffa, Barbara De Filippis, et al.. (2016). Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors. Bioorganic & Medicinal Chemistry Letters. 26(13). 3192–3194. 33 indexed citations

17.

Silva, Rafaela da, Fabrizio Montecucco, Fabiana P. Costa‐Fraga, et al.. (2015). Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice. Vascular Pharmacology. 74. 103–113. 21 indexed citations

18.

Brignole, Chiara, Danilo Marimpietri, Daniela Di Paolo, et al.. (2010). Therapeutic Targeting of TLR9 Inhibits Cell Growth and Induces Apoptosis in Neuroblastoma. Cancer Research. 70(23). 9816–9826. 60 indexed citations

19.

Bachetti, Tiziana, Daniela Di Paolo, Simona Di Lascio, et al.. (2010). PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma. PLoS ONE. 5(10). e13108–e13108. 38 indexed citations

20.

Paolo, Daniela Di, Monica Loi, Fabio Pastorino, et al.. (2009). Chapter 12 Liposome-Mediated Therapy of Neuroblastoma. Methods in enzymology on CD-ROM/Methods in enzymology. 465. 225–249. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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