Robert Vassar

32.0k total citations · 9 hit papers
135 papers, 18.9k citations indexed

About

Robert Vassar is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Robert Vassar has authored 135 papers receiving a total of 18.9k indexed citations (citations by other indexed papers that have themselves been cited), including 99 papers in Physiology, 42 papers in Molecular Biology and 36 papers in Pharmacology. Recurrent topics in Robert Vassar's work include Alzheimer's disease research and treatments (95 papers), Cholinesterase and Neurodegenerative Diseases (36 papers) and Computational Drug Discovery Methods (27 papers). Robert Vassar is often cited by papers focused on Alzheimer's disease research and treatments (95 papers), Cholinesterase and Neurodegenerative Diseases (36 papers) and Computational Drug Discovery Methods (27 papers). Robert Vassar collaborates with scholars based in United States, United Kingdom and Japan. Robert Vassar's co-authors include Sarah L. Cole, Martin Citron, Richard Axel, Riqiang Yan, Elaine Fuchs, John F. Disterhoft, Masuo Ohno, Holly D. Oakley, William A. Eimer and Bart De Strooper and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Robert Vassar

131 papers receiving 18.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

2006 2.5k citations Holly D. Oakley, Sarah L. Cole et al. Journal of Neuroscience profile →
Topographic organization of sensory projections to the olfactory bulb

1994 1.0k citations Robert Vassar et al. profile →
Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

2001 795 citations Robert Vassar et al. profile →
Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium

1993 692 citations Robert Vassar et al. profile →
The secretases: enzymes with therapeutic potential in Alzheimer disease

2010 599 citations Robert Vassar et al. profile →
Targeting the β secretase BACE1 for Alzheimer's disease therapy

2014 506 citations Robert Vassar et al. profile →
APP mouse models for Alzheimer's disease preclinical studies

2017 500 citations Robert Vassar, Takaomi C. Saido et al. profile →
BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease

2014 318 citations Robert Vassar profile →
The gut microbiome in Alzheimer’s disease: what we know and what remains to be explored

2023 174 citations Sidhanth Chandra, Sangram S. Sisodia et al. Molecular Neurodegeneration profile →

Peers

Countries citing papers authored by Robert Vassar

Since Specialization

Citations

This map shows the geographic impact of Robert Vassar's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert Vassar with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert Vassar more than expected).

Fields of papers citing papers by Robert Vassar

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert Vassar. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert Vassar. The network helps show where Robert Vassar may publish in the future.

Co-authorship network of co-authors of Robert Vassar

This figure shows the co-authorship network connecting the top 25 collaborators of Robert Vassar. A scholar is included among the top collaborators of Robert Vassar based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert Vassar. Robert Vassar is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	The UNC5C T835M mutation associated with Alzheimer’s disease leads to neurodegeneration involving oxidative stress and hippocampal atrophy in aged mice 2025 ·Molecular Neurodegeneration ·(unknown), (unknown), (unknown), (unknown), Katherine R. Sadleir, Jelena Popović, Arun K. Upadhyay, Jeffrey N. Savas, Daniele Procissi, Jasvinder K. Atwal, Robert Vassar	0
2	The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17 2025 ·Journal of Clinical Investigation ·Sidhanth Chandra, (unknown), Naveen Kumar Singhal, Elyse Watkins, Hemraj B. Dodiya, (unknown), (unknown), (unknown), (unknown), James D. Watson, Aashutosh Shetti, (unknown), Xiaoqiong Zhang, (unknown), Katherine R. Sadleir, Steven J. Schwulst, Murali Prakriya, David Gate, Sangram S. Sisodia, Robert Vassar	2
3	The Proteoform Landscape of Tau from the Human Brain 2025 ·Journal of Proteome Research ·Tian Xu, (unknown), Benjamin J. Des Soye, (unknown), (unknown), John T. Wilkins, (unknown), Jared O. Kafader, Steven M. Patrie, Robert Vassar, Neil L. Kelleher	1
4	Neuronal ACE1 knockout disrupts the hippocampal renin angiotensin system leading to memory impairment and vascular loss in normal aging 2024 ·Neurobiology of Disease ·Sohee Jeon, (unknown), (unknown), Jelena Popović, (unknown), Sidhanth Chandra, Malik Nassan, David Gate, Robert Vassar, (unknown)	2
5	Gut microbiome‐derived metabolites in Alzheimer's disease: Regulation of immunity and potential for therapeutics 2024 ·Immunological Reviews ·Sidhanth Chandra, Robert Vassar	2
6	Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer’s disease and aging 2024 ·Nature Communications ·(unknown), (unknown), (unknown), (unknown), (unknown), Elizabeth T. Bartom, (unknown), (unknown), John A. Kessler, Joseph R. Mazzulli, Andrea E. Murmann, Emily Rogalskı, Changiz Geula, Adriana Ferreira, Bradlee L. Heckmann, Douglas R. Green, Katherine R. Sadleir, Robert Vassar, Marcus E. Peter	5
7	The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms 2023 ·Molecular Neurodegeneration ·Sidhanth Chandra, Antonio Di Meco, Hemraj B. Dodiya, (unknown), (unknown), (unknown), Xiaoqiong Zhang, Katherine R. Sadleir, Sangram S. Sisodia, Robert Vassar	40
8	The gut microbiome in Alzheimer’s disease: what we know and what remains to be explored breakdown → 2023 ·Molecular Neurodegeneration ·Sidhanth Chandra, Sangram S. Sisodia, Robert Vassar	174
9	A conserved annexin A6–mediated membrane repair mechanism in muscle, heart, and nerve 2022 ·JCI Insight ·Alexis R. Demonbreun, Elena Bogdanovic, Lauren A. Vaught, Nina L. Reiser, (unknown), (unknown), (unknown), Michele Hadhazy, Patrick Page, Prem Raj B. Joseph, (unknown), (unknown), (unknown), Katherine R. Sadleir, Robert Vassar, Elizabeth M. McNally	14
10	Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice 2022 ·Molecular Neurodegeneration ·(unknown), (unknown), (unknown), Sidhanth Chandra, Tom N. Grammatopoulos, (unknown), Peter T. Lansbury, Joseph R. Mazzulli, Robert Vassar	10
11	Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosis 2022 ·PLoS ONE ·Katherine R. Sadleir, Jelena Popović, (unknown), Robert Vassar	7
12	Aβ-accelerated neurodegeneration caused by Alzheimer’s-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice 2020 ·Science Translational Medicine ·(unknown), Dmitry Prokopenko, Eric Cunningham, (unknown), Peter I. Song, Rory Kirchner, Brad Chapman, Oliver Hofmann, (unknown), Daniele Procissi, Taleen Hanania, Steven C. Leiser, Rudolph E. Tanzi, Robert Vassar	33
13	ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease 2018 ·Journal of Biological Chemistry ·Katherine R. Sadleir, Jelena Popović, Robert Vassar	38
14	Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice 2018 ·Science Translational Medicine ·(unknown), Jonathan E. Kurz, Toshihiro Nomura, Jelena Popović, Tharinda W. Rajapaksha, Hongxin Dong, Anis Contractor, Dane M. Chetkovich, Warren G. Tourtellotte, Robert Vassar	77
15	Differential Neurotoxicity Related to Tetracycline Transactivator and TDP-43 Expression in Conditional TDP-43 Mouse Model of Frontotemporal Lobar Degeneration 2018 ·Journal of Neuroscience ·Lokesh Kukreja, Ryan K. Shahidehpour, Garam Kım, (unknown), Katherine R. Sadleir, Theron A. Russell, John G. Csernansky, Marsel Mesulam, Robert Vassar, Lei Wang, Hongxin Dong, Changiz Geula	8
16	Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase 2014 ·Molecular Neurodegeneration ·Virginie Buggia-Prévot, Celia Fernandez, Sean M. Riordan, Kulandaivelu S. Vetrivel, (unknown), Jack Waters, Vytautas P. Bindokas, Robert Vassar, Gopal Thinakaran	159
17	Pyroglutamate-3 Amyloid-β Deposition in the Brains of Humans, Non-Human Primates, Canines, and Alzheimer Disease–Like Transgenic Mouse Models 2013 ·American Journal Of Pathology ·Jeffrey L. Frost, Kevin X. Le, Holger Cynis, (unknown), Martin Kleinschmidt, (unknown), Frank R. Ervin, Shikha Snigdha, Carl W. Cotman, Takaomi C. Saido, Robert Vassar, Peter St George‐Hyslop, Tsuneya Ikezu, Stephan Schilling, Hans-Ulrich Demuth, Cynthia A. Lemere	92
18	Alzheimer Disease Aβ Production in the Absence of S-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts 2008 ·Journal of Biological Chemistry ·Kulandaivelu S. Vetrivel, Xavier Meckler, Ying Chen, Phuong D. Nguyen, Nabil G. Seidah, Robert Vassar, Philip C. Wong, Masaki Fukata, Maria Z. Kounnas, Gopal Thinakaran	129
19	Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation breakdown → 2006 ·Journal of Neuroscience ·Holly D. Oakley, Sarah L. Cole, Sreemathi Logan, Erika Maus, Pei Shao, (unknown), Angela Guillozet-Bongaarts, Masuo Ohno, John F. Disterhoft, Linda Van Eldik, R. Stephen Berry, Robert Vassar	2544
20	Transgenic Overexpression of Transforming Growth Factor α Bypasses the Need for c-Ha- ras Mutations in Mouse Skin Tumorigenesis 1992 ·Molecular and Cellular Biology ·Robert Vassar, M. Elizabeth Hutton, Elaine Fuchs	15

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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