William A. Eimer

4.1k citations

19 papers · 2.9k indexed · 2 hit papers · h-index 13

Impact in

Biological Psychiatry top 0.5%
- Tryptophan and brain disorders
Neurology top 1%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in ⓘ

Biological Psychiatry 3
- Tryptophan and brain disorders 3
Neurology 5
- Neuroinflammation and Neurodegeneration Mechanisms 4

Co-authors: Robert Vassar (7 shared papers)Rudolph E. Tanzi (9 shared papers)Deepak Kumar Vijaya Kumar (7 shared papers)Robert D. Moir (6 shared papers)Kevin J. Washicosky (2 shared papers)Katherine R. Sadleir (4 shared papers)Se Hoon Choi (3 shared papers)Stephanie C. Tucker (1 shared paper)
Journals: Molecular Neurodegeneration (4 papers)Alzheimer s & Dementia (3 papers)Neuron (3 papers)Journal of Biological Chemistry (2 papers)Science Translational Medicine (1 paper)
Partner nations: United States United Kingdom Switzerland

In The Last Decade

William A. Eimer

18 papers receiving 2.9k citations

Hit Papers

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Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection 2018 · 484 citations

Peers

Countries citing papers authored by William A. Eimer

Since Specialization

Citations

This map shows the geographic impact of William A. Eimer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William A. Eimer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William A. Eimer more than expected).

Fields of papers citing papers by William A. Eimer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William A. Eimer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William A. Eimer. The network helps show where William A. Eimer may publish in the future.

Co-authors

The 25 scholars most cited alongside William A. Eimer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William A. Eimer Line = papers co-authored together William A. Eimer links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease Science Translational Medicine ·Deepak Kumar Vijaya Kumar, Se Hoon Choi, Kevin J. Washicosky, William A. Eimer, Stephanie C. Tucker, Jessica Ghofrani, Aaron Lefkowitz, Gawain McColl, Lee E. Goldstein, Rudolph E. Tanzi, Robert D. Moir Hit paper breakdown →	2016	749
2	Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection Neuron ·William A. Eimer, Deepak Kumar Vijaya Kumar, Nanda Kumar N. Shanmugam, Alex S. Rodriguez, Teryn Mitchell, Kevin J. Washicosky, Bence György, Xandra O. Breakefield, Rudolph E. Tanzi, Robert D. Moir Hit paper breakdown →	2018	484
3	Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis Neuron ·Tracy O’Connor, Katherine R. Sadleir, Erika Maus, Rodney A. Velliquette, Jie Zhao, Sarah L. Cole, William A. Eimer, Brian D. Hitt, Leslie A. Bembinster, Sven Lammich, Stefan F. Lichtenthaler, Sébastien S. Hébert, Bart De Strooper, Christian Haass, David A. Bennett, Robert Vassar	2008	344
4	Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation Molecular Neurodegeneration ·William A. Eimer, Robert Vassar	2013	318
5	APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease Journal of Biological Chemistry ·Katherine L. Youmans, Leon M. Tai, Evelyn Nwabuisi‐Heath, Lisa M. Jungbauer, Takahisa Kanekiyo, Ming Gan, Jungsu Kim, William A. Eimer, Steve Estus, G. William Rebeck, Edwin J. Weeber, Guojun Bu, Chunjiang Yu, Mary Jo LaDu	2012	214
6	The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques Acta Neuropathologica ·Patty C. Kandalepas, Katherine R. Sadleir, William A. Eimer, Jie Zhao, Daniel A. Nicholson, Robert Vassar	2013	196
7	Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level Molecular Neurodegeneration ·Katherine R. Sadleir, William A. Eimer, Sarah L. Cole, Robert Vassar	2015	168
8	Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody Molecular Neurodegeneration ·Katherine L. Youmans, Leon M. Tai, Takahisa Kanekiyo, W. Blaine Stine, Sara-Claude Michon, Evelyn Nwabuisi‐Heath, Arlene M. Manelli, Yifan Fu, Sean M. Riordan, William A. Eimer, Lester I. Binder, Guojun Bu, Chunjiang Yu, Dean M. Hartley, Mary Jo LaDu	2012	143
9	β-Site Amyloid Precursor Protein (APP)-cleaving Enzyme 1 (BACE1)-deficient Mice Exhibit a Close Homolog of L1 (CHL1) Loss-of-function Phenotype Involving Axon Guidance Defects Journal of Biological Chemistry ·Brian D. Hitt, Sean M. Riordan, Lokesh Kukreja, William A. Eimer, Tharinda W. Rajapaksha, Robert Vassar	2012	122
10	The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb Molecular Neurodegeneration ·Tharinda W. Rajapaksha, William A. Eimer, Thomas Bozza, Robert Vassar	2011	84
11	Alzheimer’s Disease: the Potential Therapeutic Role of the Natural Antibiotic amyloid-β Peptide Neurodegenerative Disease Management ·Deepak Kumar Vijaya Kumar, William A. Eimer, Rudolph E. Tanzi, Robert D. Moir	2016	34
12	Genetic Inhibition of Phosphorylation of the Translation Initiation Factor eIF2α Does Not Block Aβ-Dependent Elevation of BACE1 and APP Levels or Reduce Amyloid Pathology in a Mouse Model of Alzheimer’s Disease PLoS ONE ·Katherine R. Sadleir, William A. Eimer, Randal J. Kaufman, Pavel Osten, Robert Vassar	2014	32
13	Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease Alzheimer s & Dementia ·Richard Lathe, Nikki M. Schultek, Brian J. Balin, Garth D. Ehrlich, Lavinia Albéri, George Perry, Edward B. Breitschwerdt, David B. Corry, Richard L. Doty, Robert A. Rissman, Peter L. Nara, Ruth F. Itzhaki, William A. Eimer, Rudolph E. Tanzi	2023	18
14	Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function Molecular Therapy — Nucleic Acids ·Lilian Cruz, Bence György, Pike-See Cheah, Benjamin P. Kleinstiver, William A. Eimer, Sara P. Garcia, Nutan Sharma, Laurie J. Ozelius, D. Cristopher Bragg, J. Keith Joung, Osmar Norberto de Souza, Luís Fernando Saraiva Macedo Timmers, Xandra O. Breakefield	2020	10
15	The brain pathobiome in Alzheimer's disease Neurotherapeutics ·Nanda Kumar N. Shanmugam, William A. Eimer, Deepak Kumar Vijaya Kumar, Rudolph E. Tanzi	2024	3
16	Acute experimental colitis in 5xFAD Alzheimer's disease mice leads to enhanced monocyte infiltration into the brain accompanied by reduced β‐amyloid deposition Alzheimer s & Dementia ·Nanda Kumar N. Shanmugam, Frank Zamudio, Deepak Kumar Vijaya Kumar, Kim E. Barrett, Ryan VanDoren, Chen Meng, Olivia M. Barr, Sara E. Watson, Chih‐Chung Lin, William A. Eimer, Mehdi Jorfi, Se Hoon Choi, Robert D. Moir, Rudolph E. Tanzi	2025	2
17	Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons Nature Neuroscience ·William A. Eimer, Alex S. Rodriguez, Michael T. DeFao, Simon Ehricke, Joseph Park, Deepak Kumar Vijaya Kumar, Nanda Kumar N. Shanmugam, (unknown), Tara Sawhney, Robert D. Moir, Rudolph E. Tanzi	2025	1
18	Human amylin is a potent antimicrobial peptide that exhibits antimicrobial synergism with the amyloid beta protein Alzheimer s & Dementia ·Deepak Kumar Vijaya Kumar, Teryn Mitchell, Breeya A Tailor, Alexander P. Moir, Nanda Kumar N. Shanmugam, William A. Eimer, Jessica Ghelichi, Se Hoon Choi, Chien‐Wen Su, Alex S. Rodriguez, Eunhee Kim, Robert D. Moir, Rudolph E. Tanzi	2025	1
19	The gain-of-function TREM2-T96K mutation increases risk for Alzheimer’s disease by impairing microglial function Neuron ·Dominika Piłat, Hoang Le, Dmitry Prokopenko, Chih‐Chung Lin, William A. Eimer, Luisa Quinti, Evan P. Gavrilles, Silvia Garcı́a, Sara N Heitman, D. McGinty, Murat Çetinbaş, Ruslan I. Sadreyev, Rudolph E. Tanzi, Ana Griciuc	2025	0

About William A. Eimer

William A. Eimer is a scholar working on Biological Psychiatry, Neurology, Physiology, Pharmacology and Microbiology, having authored 19 papers that have together received 2.9k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (14 papers), Cholinesterase and Neurodegenerative Diseases (6 papers), Neuroinflammation and Neurodegeneration Mechanisms (4 papers), Computational Drug Discovery Methods (3 papers), Tryptophan and brain disorders (3 papers), RNA Research and Splicing (2 papers), Protein Hydrolysis and Bioactive Peptides (2 papers) and Nuclear Receptors and Signaling (2 papers). The work is most often cited by research in Biological Psychiatry (429 citations), Neurology (707 citations), Physiology (1.9k citations), Cellular and Molecular Neuroscience (472 citations) and Pharmacology (425 citations). William A. Eimer has collaborated with scholars based in United States, United Kingdom and Switzerland. Frequent co-authors include Robert Vassar, Rudolph E. Tanzi, Deepak Kumar Vijaya Kumar, Robert D. Moir, Kevin J. Washicosky, Katherine R. Sadleir, Se Hoon Choi, Stephanie C. Tucker, Gawain McColl and Lee E. Goldstein. Their work appears in journals such as Molecular Neurodegeneration, Alzheimer s & Dementia, Neuron, Journal of Biological Chemistry and Science Translational Medicine.

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