Gary E. Landreth

39.2k total citations · 6 hit papers
225 papers, 26.5k citations indexed

About

Gary E. Landreth is a scholar working on Molecular Biology, Physiology and Neurology. According to data from OpenAlex, Gary E. Landreth has authored 225 papers receiving a total of 26.5k indexed citations (citations by other indexed papers that have themselves been cited), including 123 papers in Molecular Biology, 75 papers in Physiology and 72 papers in Neurology. Recurrent topics in Gary E. Landreth's work include Neuroinflammation and Neurodegeneration Mechanisms (70 papers), Alzheimer's disease research and treatments (64 papers) and Peroxisome Proliferator-Activated Receptors (40 papers). Gary E. Landreth is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (70 papers), Alzheimer's disease research and treatments (64 papers) and Peroxisome Proliferator-Activated Receptors (40 papers). Gary E. Landreth collaborates with scholars based in United States, Germany and Finland. Gary E. Landreth's co-authors include Michael T. Heneka, Colin K. Combs, J. Colleen Karlo, Douglas R. McDonald, Jessica Koenigsknecht-Talboo, Erin G. Reed-Geaghan, Qingguang Jiang, Taylor R. Jay, Brandy Wilkinson and Shih-Chu Kao and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Gary E. Landreth

221 papers receiving 26.0k citations

Hit Papers

ApoE-Directed Therapeutics Rapidly Clear β-Amy... 2000 2026 2008 2017 2012 2008 2001 2010 2015 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models
    2012 854 citations Paige E. Cramer, John R. Cirrito et al. Science profile →
  2. ApoE Promotes the Proteolytic Degradation of Aβ
    2008 716 citations Qingguang Jiang, Paige E. Cramer et al. Neuron profile →
  3. β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis
    2001 617 citations J. Colleen Karlo, Gary E. Landreth et al. Journal of Neuroscience profile →
  4. The role of microglia in amyloid clearance from the AD brain
    2010 530 citations Gary E. Landreth et al. profile →
  5. TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
    2015 525 citations Taylor R. Jay, Crystal M. Miller et al. profile →
  6. Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.
    2000 506 citations J. Colleen Karlo, Gary E. Landreth et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Gary E. Landreth United States 89 11.1k 10.3k 9.0k 5.5k 4.2k 225 26.5k
Guojun Bu United States 101 12.1k 1.1× 14.8k 1.4× 6.8k 0.8× 4.6k 0.8× 2.9k 0.7× 336 30.8k
Takaomi C. Saido Japan 98 16.3k 1.5× 19.6k 1.9× 6.6k 0.7× 8.2k 1.5× 1.9k 0.4× 504 36.1k
Todd E. Golde United States 94 14.2k 1.3× 18.8k 1.8× 5.4k 0.6× 5.7k 1.0× 2.0k 0.5× 314 32.1k
Isidró Ferrer Spain 101 20.4k 1.8× 12.8k 1.2× 7.7k 0.9× 11.4k 2.1× 1.4k 0.3× 910 42.1k
Huaxi Xu United States 75 8.3k 0.7× 11.9k 1.2× 4.7k 0.5× 3.5k 0.6× 1.8k 0.4× 195 21.4k
Michael A. Moskowitz United States 94 12.8k 1.2× 7.7k 0.8× 8.6k 1.0× 7.6k 1.4× 3.1k 0.7× 230 35.7k
Serge Przedborski United States 110 14.3k 1.3× 7.8k 0.8× 8.4k 0.9× 15.3k 2.8× 1.5k 0.4× 261 41.6k
Matthias Staufenbiel Switzerland 85 9.5k 0.9× 16.8k 1.6× 6.2k 0.7× 6.5k 1.2× 774 0.2× 214 25.1k
Bruce A. Yankner United States 57 13.5k 1.2× 12.1k 1.2× 2.7k 0.3× 5.6k 1.0× 1.2k 0.3× 79 26.4k
Kazuhide Inoue Japan 69 4.8k 0.4× 8.5k 0.8× 6.4k 0.7× 6.9k 1.3× 2.0k 0.5× 290 19.7k

Countries citing papers authored by Gary E. Landreth

Since Specialization
Citations

This map shows the geographic impact of Gary E. Landreth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gary E. Landreth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gary E. Landreth more than expected).

Fields of papers citing papers by Gary E. Landreth

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gary E. Landreth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gary E. Landreth. The network helps show where Gary E. Landreth may publish in the future.

Co-authorship network of co-authors of Gary E. Landreth

This figure shows the co-authorship network connecting the top 25 collaborators of Gary E. Landreth. A scholar is included among the top collaborators of Gary E. Landreth based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gary E. Landreth. Gary E. Landreth is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Xu, Fan, Donghan Ma, Kathryn P. MacPherson, et al.. (2020). Three-dimensional nanoscopy of whole cells and tissues with in situ point spread function retrieval. Nature Methods. 17(5). 531–540. 71 indexed citations
2.
Moutinho, Miguel, Juan F. Codocedo, Shweta S. Puntambekar, & Gary E. Landreth. (2019). Nuclear Receptors as Therapeutic Targets for Neurodegenerative Diseases: Lost in Translation. PMC. 1 indexed citations
3.
Konttinen, Henna, Irina Gureviciene, Minna Oksanen, et al.. (2018). PPARβ/δ‐agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes. Glia. 67(1). 146–159. 42 indexed citations
4.
Mlodzianoski, Michael J., Shane M. Bemiller, Tyler J. McCray, et al.. (2018). Active PSF shaping and adaptive optics enable volumetric localization microscopy through brain sections. PMC. 1 indexed citations
5.
Pucilowska, Joanna, Joseph Vithayathil, Marco Pagani, et al.. (2018). Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice. Journal of Neuroscience. 38(30). 6640–6652. 63 indexed citations
6.
Jay, Taylor R., Victoria E. von Saucken, & Gary E. Landreth. (2017). TREM2 in Neurodegenerative Diseases. PMC. 2 indexed citations
7.
Jay, Taylor R., Anna Hirsch, Crystal M. Miller, et al.. (2017). Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease. Journal of Neuroscience. 37(3). 637–647. 15 indexed citations
8.
Jay, Taylor R., Anna Hirsch, Crystal M. Miller, et al.. (2016). Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease. Journal of Neuroscience. 37(3). 637–647. 347 indexed citations
9.
Pucilowska, Joanna, et al.. (2015). The 16p11.2 Deletion Mouse Model of Autism Exhibits Altered Cortical Progenitor Proliferation and Brain Cytoarchitecture Linked to the ERK MAPK Pathway. Journal of Neuroscience. 35(7). 3190–3200. 129 indexed citations
10.
Vithayathil, Joseph, Joanna Pucilowska, L. Henry Goodnough, Radhika P. Atit, & Gary E. Landreth. (2015). Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. Journal of Neuroscience. 35(17). 6836–6848. 25 indexed citations
11.
Cramer, Paige E., John R. Cirrito, Daniel W. Wesson, et al.. (2012). ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models. Science. 335(6075). 1503–1506. 854 indexed citations breakdown →
12.
Wesson, Daniel W., et al.. (2011). Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's β-Amyloidosis Mouse Model. Journal of Neuroscience. 31(44). 15962–15971. 110 indexed citations
13.
Samuels, Ivy S., Sulagna C. Saitta, & Gary E. Landreth. (2009). MAP'ing CNS Development and Cognition: An ERKsome Process. Neuron. 61(2). 160–167. 158 indexed citations
14.
Zelcer, Noam, Négar Khanlou, Qingguang Jiang, et al.. (2007). Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proceedings of the National Academy of Sciences. 104(25). 10601–10606. 291 indexed citations
15.
Heneka, Michael T., Gary E. Landreth, & Michael Hüll. (2007). Drug Insight: effects mediated by peroxisome proliferator-activated receptor-γ in CNS disorders. Nature Clinical Practice Neurology. 3(9). 496–504. 77 indexed citations
16.
Sastre, Magdalena, Ilse Dewachter, Steffen Roßner, et al.. (2006). Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ. Proceedings of the National Academy of Sciences. 103(2). 443–448. 321 indexed citations
17.
Nekrasova, Tanya, Carey L. Shive, Yuehua Gao, et al.. (2005). ERK1-Deficient Mice Show Normal T Cell Effector Function and Are Highly Susceptible to Experimental Autoimmune Encephalomyelitis. The Journal of Immunology. 175(4). 2374–2380. 66 indexed citations
18.
Breidert, Tilo, Jacques Callebert, Michael T. Heneka, et al.. (2002). Protective action of the peroxisome proliferator‐activated receptor‐γ agonist pioglitazone in a mouse model of Parkinson's disease. Journal of Neurochemistry. 82(3). 615–624. 322 indexed citations
19.
Menegay, Harry, Fred M Moeslein, & Gary E. Landreth. (1999). The Dual Specificity Protein Kinase CLK3 Is Abundantly Expressed in Mature Mouse Spermatozoa. Experimental Cell Research. 253(2). 463–473. 24 indexed citations
20.
Nel, André E., et al.. (1991). Nerve growth factor stimulates the tyrosine phosphorylation of MAP2 kinase in PC12 cells. Neuron. 6(6). 915–922. 52 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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