Riqiang Yan

11.8k total citations · 3 hit papers
99 papers, 8.1k citations indexed

About

Riqiang Yan is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Riqiang Yan has authored 99 papers receiving a total of 8.1k indexed citations (citations by other indexed papers that have themselves been cited), including 69 papers in Physiology, 45 papers in Molecular Biology and 20 papers in Cellular and Molecular Neuroscience. Recurrent topics in Riqiang Yan's work include Alzheimer's disease research and treatments (68 papers), Cholinesterase and Neurodegenerative Diseases (16 papers) and Neuroinflammation and Neurodegeneration Mechanisms (13 papers). Riqiang Yan is often cited by papers focused on Alzheimer's disease research and treatments (68 papers), Cholinesterase and Neurodegenerative Diseases (16 papers) and Neuroinflammation and Neurodegeneration Mechanisms (13 papers). Riqiang Yan collaborates with scholars based in United States, China and Russia. Riqiang Yan's co-authors include Robert Vassar, Xiangyou Hu, Wanxia He, Philip C. Wong, Brati Das, Michael J. Bienkowski, Dora M. Kovacs, Mary E. Shuck, Huiyi Miao and Bruce D. Trapp and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Riqiang Yan

97 papers receiving 8.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

1999 1.2k citations Riqiang Yan, Adele M. Pauley et al. profile →
Targeting the β secretase BACE1 for Alzheimer's disease therapy

2014 506 citations Riqiang Yan et al. profile →
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

2017 332 citations Riqiang Yan et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Riqiang Yan United States	42	4.4k	3.3k	1.8k	1.4k	1.3k	99	8.1k
Stefan F. Lichtenthaler Germany	55	4.3k 1.0×	4.2k 1.3×	1.4k 0.8×	1.3k 1.0×	910 0.7×	182	9.0k
Nobuhisa Iwata Japan	50	6.8k 1.5×	4.4k 1.3×	1.8k 1.0×	2.9k 2.1×	861 0.7×	142	11.6k
Steven Estus United States	44	4.4k 1.0×	4.4k 1.4×	933 0.5×	1.5k 1.1×	526 0.4×	87	8.3k
Jochen Walter Germany	60	6.0k 1.3×	5.3k 1.6×	1.5k 0.8×	2.3k 1.7×	740 0.6×	148	11.6k
Mary Jo LaDu United States	51	7.1k 1.6×	3.8k 1.2×	1.3k 0.7×	2.0k 1.5×	962 0.8×	105	9.6k
Tilman Oltersdorf United States	33	5.0k 1.1×	5.9k 1.8×	1.3k 0.7×	1.2k 0.9×	874 0.7×	52	10.4k
M. Paul Murphy United States	43	5.8k 1.3×	3.4k 1.0×	1.4k 0.8×	2.1k 1.5×	732 0.6×	75	8.9k
Luciano D'adamio United States	47	3.5k 0.8×	3.9k 1.2×	953 0.5×	1.5k 1.1×	362 0.3×	109	7.1k
Jorge Busciglio United States	43	4.3k 1.0×	3.5k 1.1×	996 0.6×	1.7k 1.2×	392 0.3×	65	7.9k
Gopal Thinakaran United States	57	8.9k 2.0×	6.0k 1.8×	2.2k 1.2×	2.5k 1.8×	958 0.8×	121	12.1k

Countries citing papers authored by Riqiang Yan

Since Specialization

Citations

This map shows the geographic impact of Riqiang Yan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Riqiang Yan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Riqiang Yan more than expected).

Fields of papers citing papers by Riqiang Yan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Riqiang Yan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Riqiang Yan. The network helps show where Riqiang Yan may publish in the future.

Co-authorship network of co-authors of Riqiang Yan

This figure shows the co-authorship network connecting the top 25 collaborators of Riqiang Yan. A scholar is included among the top collaborators of Riqiang Yan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Riqiang Yan. Riqiang Yan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Leclair, Nathan K., Omar M. Omar, Aamir Zuberi, et al.. (2025). Amyotrophic lateral sclerosis and frontotemporal dementia mutation reduces endothelial TDP-43 and causes blood-brain barrier defects. Science Advances. 11(16). eads0505–eads0505. 3 indexed citations

Huang, Hao, Md Golam Sharoar, Liang‐Liang Fan, et al.. (2024). Accumulation of neutral lipids in dystrophic neurites surrounding amyloid plaques in Alzheimer's disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1870(4). 167086–167086. 4 indexed citations

Li, Xu‐Hui, et al.. (2024). Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice. Molecular Psychiatry. 29(8). 2496–2509. 5 indexed citations

Zhang, Chenyu, et al.. (2024). Leveraging Mutual Information for Functional Annotation Analysis of Microglia in Alzheimer's Disease. 1–10.

Ishii, Akihiro, Omar M. Omar, Yingying Ge, et al.. (2024). Contribution of amyloid deposition from oligodendrocytes in a mouse model of Alzheimer’s disease. Molecular Neurodegeneration. 19(1). 83–83. 10 indexed citations

Zhu, Mei, et al.. (2024). Ex vivo propagation of synaptically-evoked cortical depolarizations in a mouse model of Alzheimer’s disease at 20 Hz, 40 Hz, or 83 Hz. Scientific Reports. 14(1). 23365–23365.

Iqbal, Javed, et al.. (2023). Klotho Regulated by Estrogen Plays a Key Role in Sex Differences in Stress Resilience in Rats. International Journal of Molecular Sciences. 24(2). 1206–1206. 20 indexed citations

Zhou, John, Qi Shi, Wanxia He, et al.. (2023). Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development. Human Molecular Genetics. 32(16). 2587–2599. 2 indexed citations

Sharoar, Md Golam, Xiangyou Hu, Xin‐Ming Ma, Xiongwei Zhu, & Riqiang Yan. (2019). Sequential formation of different layers of dystrophic neurites in Alzheimer’s brains. Molecular Psychiatry. 24(9). 1369–1382. 54 indexed citations

10.

Das, Brati & Riqiang Yan. (2017). Role of BACE1 in Alzheimer’s synaptic function. Translational Neurodegeneration. 6(1). 23–23. 99 indexed citations

11.

Yan, Riqiang. (2016). Stepping closer to treating Alzheimer’s disease patients with BACE1 inhibitor drugs. Translational Neurodegeneration. 5(1). 13–13. 81 indexed citations

12.

Hu, Xiangyou, Qingyuan Fan, Hailong Hou, & Riqiang Yan. (2015). Neurological dysfunctions associated with altered BACE1‐dependent Neuregulin‐1 signaling. Journal of Neurochemistry. 136(2). 234–249. 41 indexed citations

13.

Luo, Xiaoyang, Wanxia He, Xiangyou Hu, & Riqiang Yan. (2013). Reversible Overexpression of Bace1-Cleaved Neuregulin-1 N-Terminal Fragment Induces Schizophrenia-Like Phenotypes in Mice. Biological Psychiatry. 76(2). 120–127. 43 indexed citations

14.

Prior, Marguerite, et al.. (2010). RTN/Nogo in forming Alzheimer's neuritic plaques. Neuroscience & Biobehavioral Reviews. 34(8). 1201–1206. 20 indexed citations

15.

Heath, Jonathon, Sandra L. Siedlak, Xiongwei Zhu, et al.. (2010). Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 30(6). 574–579. 18 indexed citations

16.

Yan, Riqiang. (2009). CHI's Eighth Annual World Pharmaceutical Congress. Targeting Alzheimer's with novel therapeutics: Part 2.. PubMed. 12(8). 482–4. 1 indexed citations

17.

Shi, Qi, Marguerite Prior, Wanxia He, et al.. (2009). Reduced Amyloid Deposition in Mice Overexpressing RTN3 Is Adversely Affected by Preformed Dystrophic Neurites. Journal of Neuroscience. 29(29). 9163–9173. 52 indexed citations

18.

Breij, Esther C.W., Rob Veerhuis, Rianka P. M. Vloet, et al.. (2008). Homogeneity of active demyelinating lesions in established multiple sclerosis. Annals of Neurology. 63(1). 16–25. 255 indexed citations

19.

He, Wanxia, Qi Shi, Xiangyou Hu, & Riqiang Yan. (2007). The Membrane Topology of RTN3 and Its Effect on Binding of RTN3 to BACE1. Journal of Biological Chemistry. 282(40). 29144–29151. 38 indexed citations

20.

Li, Jinhe, Adele M. Pauley, John R. Brashler, et al.. (2002). SEL‐10 interacts with presenilin 1, facilitates its ubiquitination, and alters A‐beta peptide production. Journal of Neurochemistry. 82(6). 1540–1548. 58 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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