Christopher Liddle

21.8k total citations · 10 hit papers
156 papers, 14.4k citations indexed

About

Christopher Liddle is a scholar working on Epidemiology, Molecular Biology and Oncology. According to data from OpenAlex, Christopher Liddle has authored 156 papers receiving a total of 14.4k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Epidemiology, 42 papers in Molecular Biology and 37 papers in Oncology. Recurrent topics in Christopher Liddle's work include Liver Disease Diagnosis and Treatment (44 papers), Pharmacogenetics and Drug Metabolism (32 papers) and Hepatitis C virus research (23 papers). Christopher Liddle is often cited by papers focused on Liver Disease Diagnosis and Treatment (44 papers), Pharmacogenetics and Drug Metabolism (32 papers) and Hepatitis C virus research (23 papers). Christopher Liddle collaborates with scholars based in Australia, United States and Brazil. Christopher Liddle's co-authors include Michael Downes, Ronald M. Evans, Annette R. Atkins, Geoffrey C. Farrell, Bryan Goodwin, Ruth T. Yu, Nasun Hah, Jae Myoung Suh, Maryam Ahmadian and Jacob George and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Christopher Liddle

154 papers receiving 14.2k citations

Hit Papers

PPARγ signaling and metabolism: the goo... 1998 2026 2007 2016 2013 2002 2012 2000 1999 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. PPARγ signaling and metabolism: the good, the bad and the future
    2013 1.5k citations Nasun Hah, Christopher Liddle et al. profile →
  2. NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
    2002 936 citations Shivakumar Chitturi, Shehan Abeygunasekera et al. Hepatology profile →
  3. Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
    2012 831 citations Ruth T. Yu, Annette R. Atkins et al. Nature profile →
  4. Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands
    2000 684 citations Bryan Goodwin, Christopher Liddle et al. profile →
  5. The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation ofCYP3A4by Rifampicin through a Distal Enhancer Module
    1999 558 citations Bryan Goodwin, Christopher Liddle et al. profile →
  6. Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis
    1998 503 citations Martin Weltman, Geoffrey C. Farrell et al. Hepatology profile →
  7. A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
    2013 490 citations Ning Ding, Ruth T. Yu et al. profile →
  8. FXR Regulates Intestinal Cancer Stem Cell Proliferation
    2019 331 citations Sally Coulter, Eiji Yoshihara et al. profile →
  9. Immune-evasive human islet-like organoids ameliorate diabetes
    2020 253 citations Eiji Yoshihara, Carolyn O’Connor et al. Nature profile →
  10. Lean NAFLD: A Distinct Entity Shaped by Differential Metabolic Adaptation
    2019 240 citations Ali Bayoumi, Sally Coulter et al. Hepatology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Christopher Liddle Australia 57 4.5k 4.5k 3.0k 2.6k 2.5k 156 14.4k
Makoto Makishima Japan 45 3.9k 0.9× 5.7k 1.3× 4.9k 1.7× 2.0k 0.8× 1.2k 0.5× 258 16.6k
Wendong Huang United States 58 2.4k 0.5× 5.6k 1.2× 3.7k 1.2× 1.0k 0.4× 1.6k 0.6× 179 12.1k
Antonio Moschetta Italy 56 3.9k 0.9× 5.4k 1.2× 4.9k 1.6× 1.2k 0.5× 608 0.2× 202 13.8k
José C. Fernández‐Checa Spain 74 4.0k 0.9× 7.4k 1.7× 1.2k 0.4× 1.1k 0.4× 1.0k 0.4× 190 15.0k
Philippe Lefèbvre France 48 3.4k 0.8× 6.6k 1.5× 1.9k 0.6× 1.7k 0.7× 386 0.2× 180 12.5k
Folkert Kuipers Netherlands 80 5.6k 1.2× 8.7k 1.9× 9.6k 3.2× 3.3k 1.3× 1.3k 0.5× 461 23.8k
Joyce J. Repa United States 55 3.6k 0.8× 10.2k 2.3× 8.0k 2.7× 2.4k 0.9× 1.2k 0.5× 101 21.1k
Christopher J. Sinal Canada 43 3.1k 0.7× 2.6k 0.6× 3.2k 1.1× 757 0.3× 938 0.4× 85 9.0k
Hiromasa Ishii Japan 54 2.7k 0.6× 3.3k 0.7× 964 0.3× 679 0.3× 923 0.4× 462 11.8k
Maurizio Parola Italy 54 4.4k 1.0× 3.1k 0.7× 993 0.3× 676 0.3× 944 0.4× 167 10.5k

Countries citing papers authored by Christopher Liddle

Since Specialization
Citations

This map shows the geographic impact of Christopher Liddle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher Liddle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher Liddle more than expected).

Fields of papers citing papers by Christopher Liddle

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher Liddle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher Liddle. The network helps show where Christopher Liddle may publish in the future.

Co-authorship network of co-authors of Christopher Liddle

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher Liddle. A scholar is included among the top collaborators of Christopher Liddle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher Liddle. Christopher Liddle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wang, Hui, Weiwei Fan, Sihao Liu, et al.. (2025). BCL6 coordinates muscle mass homeostasis with nutritional states. Proceedings of the National Academy of Sciences. 122(4). e2408896122–e2408896122. 2 indexed citations
2.
Hong, Suk-Hyun, Glenda Castro, Dan Wang, et al.. (2024). Targeting nuclear receptor corepressors for reversible male contraception. Proceedings of the National Academy of Sciences. 121(9). e2320129121–e2320129121. 2 indexed citations
3.
Pan, Ziyan, Ali Bayoumi, Brian Gloss, et al.. (2024). Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease. Science Translational Medicine. 16(741). eadj0133–eadj0133. 15 indexed citations
4.
Dwyer, Amy R., Thu H. Truong, Raisa I. Krutilina, et al.. (2023). Glucocorticoid Receptors Drive Breast Cancer Cell Migration and Metabolic Reprogramming via PDK4. Endocrinology. 164(7). 22 indexed citations
5.
Bayoumi, Ali, Khaled Thabet, Ziyan Pan, et al.. (2022). A metabolic associated fatty liver disease risk variant in MBOAT7 regulates toll like receptor induced outcomes. Nature Communications. 13(1). 7430–7430. 29 indexed citations
6.
Fu, Ting, Tae Gyu Oh, Fritz Cayabyab, et al.. (2022). FXR mediates ILC-intrinsic responses to intestinal inflammation. Proceedings of the National Academy of Sciences. 119(51). e2213041119–e2213041119. 40 indexed citations
7.
Keinan, Omer, Joseph M. Valentine, Haopeng Xiao, et al.. (2021). Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes. Nature. 599(7884). 296–301. 51 indexed citations
8.
Zhou, Gang, Shuanglin Han, Zhiqiang Zhang, et al.. (2020). An aptamer-based drug delivery agent (CD133-apt-Dox) selectively and effectively kills liver cancer stem-like cells. Cancer Letters. 501. 124–132. 54 indexed citations
9.
Yoshihara, Eiji, Carolyn O’Connor, Emanuel Gasser, et al.. (2020). Immune-evasive human islet-like organoids ameliorate diabetes. Nature. 586(7830). 606–611. 253 indexed citations breakdown →
10.
Trousil, Sebastian, Robert J. Edwards, Jingky Lozano-Kühne, et al.. (2019). Altered cytochrome 2E1 and 3A P450‐dependent drug metabolism in advanced ovarian cancer correlates to tumour‐associated inflammation. British Journal of Pharmacology. 176(18). 3712–3722. 18 indexed citations
11.
Fox, Peter, Rosemary L. Balleine, Bo Gao, et al.. (2016). Dose Escalation of Tamoxifen in Patients with Low Endoxifen Level: Evidence for Therapeutic Drug Monitoring—The TADE Study. Clinical Cancer Research. 22(13). 3164–3171. 64 indexed citations
12.
Ding, Ning, Nasun Hah, Ruth T. Yu, et al.. (2015). BRD4 is a novel therapeutic target for liver fibrosis. Proceedings of the National Academy of Sciences. 112(51). 15713–15718. 171 indexed citations
13.
Arensman, Michael D., Phillip Nguyen, Kathleen M. Kershaw, et al.. (2015). Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Molecular Cancer Research. 13(11). 1509–1519. 37 indexed citations
14.
Vanwijngaerden, Yoo-Mee, Lies Langouche, Sarah Derde, et al.. (2013). Impact of Parenteral Nutrition Versus Fasting on Hepatic Bile Acid Production and Transport in a Rabbit Model of Prolonged Critical Illness. Shock. 41(1). 48–54. 10 indexed citations
15.
Subramaniam, Nanthakumar, Mara H. Sherman, Renuka Rao, et al.. (2012). Metformin-Mediated Bambi Expression in Hepatic Stellate Cells Induces Prosurvival Wnt/β-Catenin Signaling. Cancer Prevention Research. 5(4). 553–561. 28 indexed citations
16.
Coulter, Sally, Christopher Liddle, Anne Wong, et al.. (2011). FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways. PLoS ONE. 6(3). e17868–e17868. 150 indexed citations
17.
Stedman, Catherine, Christopher Liddle, Sally Coulter, et al.. (2006). Benefit of farnesoid X receptor inhibition in obstructive cholestasis. Proceedings of the National Academy of Sciences. 103(30). 11323–11328. 148 indexed citations
18.
Spurdle, Amanda B., Bryan Goodwin, John L. Hopper, et al.. (2002). The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer. Pharmacogenetics. 12(5). 355–366. 112 indexed citations
19.
Chitturi, Shivakumar, Shehan Abeygunasekera, Geoffrey C. Farrell, et al.. (2002). NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology. 35(2). 373–379. 936 indexed citations breakdown →
20.
Robertson, Graham, Geoffrey C. Farrell, & Christopher Liddle. (1998). Sexually Dimorphic Expression of Rat CYP3A9 and CYP3A18 Genes Is Regulated by Growth Hormone. Biochemical and Biophysical Research Communications. 242(1). 57–60. 49 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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