Barrie E. Kirk

620 citations

19 papers · 476 indexed · h-index 13

Co-authors: Keith Biggadike Anne M. Exall Alan D. Borthwick Stanley M. Roberts Anne M. Hassell Eugene L. Stewart Iain M. McLay Lisa M. Shewchuk
Topics: Fluorine in Organic Chemistry (6 papers)Plant biochemistry and biosynthesis (6 papers)Microbial Natural Products and Biosynthesis (5 papers)
Cited by: Pharmaceutical Science Virology Organic Chemistry
Journals: Journal of Medicinal Chemistry Bioorganic & Medicinal Chemistry Letters Journal of the Chemical Society Perkin Transactions 1
Partner nations: United Kingdom Germany

In The Last Decade

Barrie E. Kirk

19 papers receiving 404 citations

Peers

Countries citing papers authored by Barrie E. Kirk

Since Specialization

Citations

This map shows the geographic impact of Barrie E. Kirk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Barrie E. Kirk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Barrie E. Kirk more than expected).

Fields of papers citing papers by Barrie E. Kirk

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Barrie E. Kirk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Barrie E. Kirk. The network helps show where Barrie E. Kirk may publish in the future.

Co-authorship network of co-authors of Barrie E. Kirk

This figure shows the co-authorship network connecting the top 25 collaborators of Barrie E. Kirk. A scholar is included among the top collaborators of Barrie E. Kirk based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Barrie E. Kirk. Barrie E. Kirk is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain 2008 ·Journal of Medicinal Chemistry ·Keith Biggadike,Randy K. Bledsoe,Anne M. Hassell,Barrie E. Kirk,Iain M. McLay,Lisa M. Shewchuk,Eugene L. Stewart	88
2	The Squalestatins: Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in Vivo Evaluation of C3-Modified Analogues 1996 ·Journal of Medicinal Chemistry ·Panayiotis A. Procopiou,Brian J. Cox,Barrie E. Kirk,Michael Lester,Alun D. McCarthy,(unknown),(unknown),Michael Snowden,(unknown),Nigel S. Watson,(unknown)	20
3	The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogs; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectronic Heterocyclic Functionality 1995 ·Journal of Medicinal Chemistry ·Mark J. Bamford,(unknown),(unknown),Brian Dymock,(unknown),(unknown),Barrie E. Kirk,Michael Lester,Panayiotis A. Procopiou	11
4	The Squalestatins: Novel Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in vivo Evaluation of C1-Modified Analogs 1994 ·Journal of Medicinal Chemistry ·Panayiotis A. Procopiou,(unknown),Mark J. Bamford,(unknown),Brian Dymock,J. Graeme Houston,Julie L. Hutson,Barrie E. Kirk,Alun D. McCarthy	16
5	The squalestatins: Potent inhibitors of squalene synthase, 3-hydroxymethyl derivatives. 1994 ·Bioorganic & Medicinal Chemistry Letters ·Brian J. Cox,Julie L. Hutson,(unknown),Barrie E. Kirk,(unknown),Nigel S. Watson	7
6	Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of 3-hydroxy-3-methylglutarate-CoA reductase inhibitors 1993 ·Journal of Medicinal Chemistry ·Chi Ho Chan,(unknown),(unknown),(unknown),Julie L. Hutson,Graham G. A. Inglis,Paul S. Jones,(unknown),Barrie E. Kirk	21
7	The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety. 1993 ·Bioorganic & Medicinal Chemistry Letters ·Nigel S. Watson,(unknown),(unknown),Brian J. Cox,Julie L. Hutson,(unknown),Barrie E. Kirk,Panayiotis A. Procopiou,(unknown),(unknown)	16
8	The squalestatins: novel inhibitors of squalene synthase. The optimal C1 chain-length requirements. 1993 ·Bioorganic & Medicinal Chemistry Letters ·Panayiotis A. Procopiou,(unknown),Julie L. Hutson,Barrie E. Kirk,(unknown),(unknown),Nigel S. Watson	12
9	Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxyguanosines 1991 ·Journal of Medicinal Chemistry ·Alan D. Borthwick,Barrie E. Kirk,Keith Biggadike,Anne M. Exall,(unknown),Stanley M. Roberts,D. J. E. Knight,Jonathan A. Coates,D. M. Ryan	44
10	Fluoro carbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-iodouracil 1990 ·Journal of Medicinal Chemistry ·Alan D. Borthwick,(unknown),Barrie E. Kirk,Keith Biggadike,Anne M. Exall,(unknown),Stanley M. Roberts,D. J. E. Knight,Jonathan A. Coates	46
11	2′-Deoxy-2′-fluoro-ara-aristeromycin, a new anti-herpes agent: the first direct introduction of a 2′-fluoro substituent into a carbocyclic nucleoside 1988 ·Journal of the Chemical Society Chemical Communications ·Keith Biggadike,Alan D. Borthwick,Anne M. Exall,Barrie E. Kirk,Richard A. Ward	12
12	Synthesis and enzymatic resolution of carbocyclic 2′-ara-fluoro-guanosine: a potent new anti-herpetic agent 1988 ·Journal of the Chemical Society Chemical Communications ·Alan D. Borthwick,(unknown),Keith Biggadike,Anne M. Exall,Stanley M. Roberts,(unknown),Barrie E. Kirk,(unknown),J. M. Cameron,Susan Cox,(unknown),(unknown)	42
13	Use of diethylaminosulphur trifluoride (DAST) in the preparation of synthons of carbocyclic nucleosides 1988 ·Journal of the Chemical Society Perkin Transactions 1 ·Keith Biggadike,Alan D. Borthwick,(unknown),Anne M. Exall,Barrie E. Kirk,Stanley M. Roberts,(unknown),(unknown)	41
14	Synthesis of fluorinated carbocyclic nucleosides: preparation of carbocyclic 1-(2′-deoxy-6′-fluororibofuranosyl)-5-iodouracils 1987 ·Journal of the Chemical Society Chemical Communications ·Keith Biggadike,Alan D. Borthwick,Anne M. Exall,Barrie E. Kirk,Stanley M. Roberts,(unknown),Alexandra M. Z. Slawin,David J. Williams	24
15	Short convergent route to homochiral carbocyclic-2′-deoxynucleosides and carbocyclic ribonucleosides 1987 ·Journal of the Chemical Society Chemical Communications ·Keith Biggadike,Alan D. Borthwick,Anne M. Exall,Barrie E. Kirk,Stanley M. Roberts,(unknown)	30
16	Synthesis of fluorinated carbocyclic nucleosides: preparation of (±)-carbocyclic-FMAU and some congeners 1987 ·Journal of the Chemical Society Chemical Communications ·Keith Biggadike,Alan D. Borthwick,(unknown),Anne M. Exall,Barrie E. Kirk,(unknown),(unknown),(unknown),Alexandra M. Z. Slawin,David Williams	15
17	Allene cycloadditions. Part V. Temperature dependence of product distribution in alkylallene–alkyne reactions 1974 ·Journal of the Chemical Society Perkin Transactions 1 ·Barrie E. Kirk,David R. Taylor	11
18	Ene reactions of allenes. Part II. Non-stereospecific ene insertions into an alkylallene by electron deficient acetylenes 1974 ·Journal of the Chemical Society Perkin Transactions 1 ·(unknown),Barrie E. Kirk,David R. Taylor	15
19	Ene reactions of alkylallenes 1971 ·Journal of the Chemical Society D Chemical Communications ·(unknown),Barrie E. Kirk,D. R. Taylor	5

About Barrie E. Kirk

Barrie E. Kirk is a scholar working on Pharmaceutical Science, Pharmacology and Computational Theory and Mathematics, having authored 19 papers that have together received 476 indexed citations. Recurring topics across this work include Fluorine in Organic Chemistry (6 papers), Plant biochemistry and biosynthesis (6 papers) and Microbial Natural Products and Biosynthesis (5 papers). The work is most often cited by research in Pharmaceutical Science (59 citations), Virology (37 citations) and Organic Chemistry (202 citations). Barrie E. Kirk has collaborated with scholars based in United Kingdom and Germany. Frequent co-authors include Keith Biggadike, Anne M. Exall, Alan D. Borthwick, Stanley M. Roberts, Anne M. Hassell, Eugene L. Stewart, Iain M. McLay, Lisa M. Shewchuk, Randy K. Bledsoe and David R. Taylor. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters and Journal of the Chemical Society Perkin Transactions 1.

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