Tony Hunter

133.6k total citations · 51 hit papers
504 papers, 103.8k citations indexed

About

Tony Hunter is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Tony Hunter has authored 504 papers receiving a total of 103.8k indexed citations (citations by other indexed papers that have themselves been cited), including 399 papers in Molecular Biology, 122 papers in Oncology and 107 papers in Cell Biology. Recurrent topics in Tony Hunter's work include Ubiquitin and proteasome pathways (66 papers), Protein Kinase Regulation and GTPase Signaling (66 papers) and Microtubule and mitosis dynamics (55 papers). Tony Hunter is often cited by papers focused on Ubiquitin and proteasome pathways (66 papers), Protein Kinase Regulation and GTPase Signaling (66 papers) and Microtubule and mitosis dynamics (55 papers). Tony Hunter collaborates with scholars based in United States, United Kingdom and Japan. Tony Hunter's co-authors include Jonathan A. Cooper, Steven K. Hanks, Jonathon Pines, Bartholomew M. Sefton, Peter Blume‐Jensen, Gerard Manning, Anne Marie Quinn, Sucha Sudarsanam, Michael Karin and David D. Schlaepfer and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Tony Hunter

501 papers receiving 100.1k citations

Hit Papers

The Protein Kinase Complement of the Hum... 1975 2026 1992 2009 2002 1988 2001 1995 1995 2.0k 4.0k 6.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Protein Kinase Complement of the Human Genome
    2002 6.2k citations Gerard Manning, Tony Hunter et al. profile →
  2. The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
    1988 4.4k citations Tony Hunter et al. profile →
  3. Oncogenic kinase signalling
    2001 2.9k citations Tony Hunter et al. profile →
  4. Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling
    1995 2.4k citations Tony Hunter profile →
  5. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification.
    1995 2.1k citations Tony Hunter et al. profile →
  6. Signaling—2000 and Beyond
    2000 2.1k citations Tony Hunter profile →
  7. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine
    1980 2.1k citations Tony Hunter, Bartholomew M. Sefton Proceedings of the National Academy of Sciences profile →
  8. PROTEIN-TYROSINE KINASES
    1985 1.9k citations Tony Hunter et al. profile →
  9. Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
    1994 1.8k citations Tony Hunter et al. profile →
  10. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    1994 1.8k citations Tony Hunter et al. profile →
  11. Protein Tyrosine Phosphatases in the Human Genome
    2004 1.5k citations Tony Hunter et al. profile →
  12. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
    1994 1.4k citations Tony Hunter et al. profile →
  13. [11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
    1991 1.4k citations Tony Hunter et al. profile →
  14. The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes
    1988 1.2k citations Tony Hunter et al. profile →
  15. The regulation of transcription by phosphorylation
    1992 1.1k citations Tony Hunter et al. profile →
  16. [42] Detection and quantification of phosphotyrosine in proteins
    1983 1.1k citations Bartholomew M. Sefton, Tony Hunter et al. profile →
  17. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
    1999 952 citations Jill Meisenhelder, Tony Hunter et al. Proceedings of the National Academy of Sciences profile →
  18. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
    1991 949 citations Tony Hunter et al. profile →
  19. A thousand and one protein kinases
    1987 912 citations Tony Hunter profile →
  20. The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase
    1999 894 citations Tony Hunter et al. profile →
  21. Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro
    1989 878 citations Jill Meisenhelder, Tony Hunter et al. profile →
  22. Oncogene jun encodes a sequence-specific trans- activator similar to AP-1
    1988 867 citations Tony Hunter et al. profile →
  23. Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein
    1984 857 citations Tony Hunter, Inder M. Verma et al. profile →
  24. Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2
    1989 821 citations Tony Hunter et al. profile →
  25. Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport.
    1991 747 citations Tony Hunter et al. profile →
  26. The Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond
    2007 745 citations Tony Hunter profile →
  27. Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity
    2007 724 citations Jill Meisenhelder, Tony Hunter et al. profile →
  28. Evolution of protein kinase signaling from yeast to man
    2002 716 citations Gerard Manning, Tony Hunter et al. profile →
  29. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor
    1991 703 citations Tony Hunter et al. profile →
  30. trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.
    1991 697 citations Tony Hunter et al. Molecular and Cellular Biology profile →
  31. PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
    2012 672 citations Tony Hunter et al. profile →
  32. Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B
    1990 666 citations Tony Hunter et al. profile →
  33. Inappropriate Activation of the TSC/Rheb/mTOR/S6K Cassette Induces IRS1/2 Depletion, Insulin Resistance, and Cell Survival Deficiencies
    2004 655 citations Tony Hunter et al. profile →
  34. Cooperation between oncogenes
    1991 655 citations Tony Hunter profile →
  35. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus
    1995 641 citations Tony Hunter et al. profile →
  36. C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.
    1984 629 citations Jill Meisenhelder, Tony Hunter et al. profile →
  37. Structural basis for phosphoserine-proline recognition by group IV WW domains.
    2000 609 citations Tony Hunter et al. profile →
  38. Cyclins and cancer
    1991 607 citations Tony Hunter et al. profile →
  39. Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent
    1997 604 citations Tony Hunter et al. profile →
  40. Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells
    1981 602 citations Tony Hunter et al. profile →
  41. Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane
    1984 577 citations Tony Hunter et al. profile →
  42. Tyrosine phosphorylation: thirty years and counting
    2009 542 citations Tony Hunter profile →
  43. Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
    2003 532 citations Tony Hunter et al. profile →
  44. Structure-based prediction of protein–protein interactions on a genome-wide scale
    2012 527 citations Tony Hunter et al. profile →
  45. A Structural Basis for Substrate Specificities of Protein Ser/Thr Kinases: Primary Sequence Preference of Casein Kinases I and II, NIMA, Phosphorylase Kinase, Calmodulin-Dependent Kinase II, CDK5, and Erk1
    1996 500 citations Merl F. Hoekstra, Tony Hunter et al. Molecular and Cellular Biology profile →
  46. Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus
    1980 495 citations Bartholomew M. Sefton, Tony Hunter et al. profile →
  47. Tyr 527 Is Phosphorylated in pp60 c- src : Implications for Regulation
    1986 489 citations Kathleen L. Gould, Christine A. Cartwright et al. profile →
  48. Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation
    2016 458 citations Xinde Zheng, Tony Hunter et al. eLife profile →
  49. An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates
    1979 428 citations Walter Eckhart, Tony Hunter et al. profile →
  50. Messenger RNA for the coat protein of tobacco mosaic virus
    1976 220 citations Tony Hunter et al. profile →
  51. The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates
    1975 216 citations Tony Hunter et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Tony Hunter United States 155 77.6k 23.2k 17.5k 11.8k 9.5k 504 103.8k
Lewis C. Cantley United States 183 104.9k 1.4× 27.4k 1.2× 19.6k 1.1× 16.8k 1.4× 7.3k 0.8× 710 150.4k
John C. Reed United States 161 73.3k 0.9× 21.4k 0.9× 10.1k 0.6× 20.4k 1.7× 6.1k 0.6× 799 107.5k
Joseph Schlessinger United States 156 68.0k 0.9× 24.9k 1.1× 16.4k 0.9× 12.5k 1.1× 6.6k 0.7× 529 96.4k
Roger J. Davis United States 146 62.3k 0.8× 15.6k 0.7× 11.7k 0.7× 13.6k 1.1× 4.2k 0.4× 572 92.6k
Tony Pawson Canada 139 49.8k 0.6× 10.9k 0.5× 13.1k 0.7× 9.8k 0.8× 4.6k 0.5× 447 68.5k
Douglas Hanahan United States 109 79.7k 1.0× 43.8k 1.9× 9.5k 0.5× 19.2k 1.6× 13.4k 1.4× 230 137.2k
Ira Pastan United States 146 45.5k 0.6× 30.0k 1.3× 7.5k 0.4× 20.3k 1.7× 10.2k 1.1× 1.2k 90.1k
Joan Massagué United States 184 95.5k 1.2× 47.2k 2.0× 12.7k 0.7× 12.3k 1.0× 9.3k 1.0× 362 137.5k
Philip Cohen United Kingdom 143 67.4k 0.9× 9.8k 0.4× 13.5k 0.8× 8.8k 0.7× 4.5k 0.5× 489 89.2k
Ruedi Aebersold Switzerland 160 86.7k 1.1× 9.0k 0.4× 9.8k 0.6× 8.5k 0.7× 6.4k 0.7× 783 117.7k

Countries citing papers authored by Tony Hunter

Since Specialization
Citations

This map shows the geographic impact of Tony Hunter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tony Hunter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tony Hunter more than expected).

Fields of papers citing papers by Tony Hunter

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tony Hunter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tony Hunter. The network helps show where Tony Hunter may publish in the future.

Co-authorship network of co-authors of Tony Hunter

This figure shows the co-authorship network connecting the top 25 collaborators of Tony Hunter. A scholar is included among the top collaborators of Tony Hunter based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tony Hunter. Tony Hunter is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Hunter, Tony, Nicole Noren Hooten, Holger Maul, et al.. (2025). Association of psychosocial stress and poverty with plasma and extracellular vesicle mitochondrial DNA levels. Psychoneuroendocrinology. 182. 107622–107622.
3.
Hsu, Cynthia L., Kohta Ohnishi, Jill Meisenhelder, et al.. (2023). MAP4K3 inhibits Sirtuin-1 to repress the LKB1–AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex. Life Science Alliance. 6(8). e202201525–e202201525. 2 indexed citations
4.
Lewis, Benjamin M., et al.. (2023). LARP4 is an RNA-binding protein that binds nuclear-encoded mitochondrial mRNAs to promote mitochondrial function. RNA. 30(3). 223–239. 9 indexed citations
5.
Lamarche, Brandon J., Nicole I. Orazio, Jill Meisenhelder, et al.. (2018). Repair of protein-linked DNA double strand breaks: Using the adenovirus genome as a model substrate in cell-based assays. DNA repair. 74. 80–90. 6 indexed citations
6.
Settleman, Jeffrey, Charles L. Sawyers, & Tony Hunter. (2018). Challenges in validating candidate therapeutic targets in cancer. eLife. 7. 19 indexed citations
7.
Zheng, Xinde & Tony Hunter. (2014). Pink1, the first ubiquitin kinase. The EMBO Journal. 33(15). 1621–1623. 20 indexed citations
8.
Copp, Jeremy, Gerard Manning, & Tony Hunter. (2009). TORC-Specific Phosphorylation of Mammalian Target of Rapamycin (mTOR): Phospho-Ser2481 Is a Marker for Intact mTOR Signaling Complex 2. Cancer Research. 69(5). 1821–1827. 356 indexed citations
9.
Bailis, Julie M., Douglas D. Luche, Tony Hunter, & Susan L. Forsburg. (2008). Minichromosome Maintenance Proteins Interact with Checkpoint and Recombination Proteins To Promote S-Phase Genome Stability. Molecular and Cellular Biology. 28(5). 1724–1738. 65 indexed citations
10.
You, Zhongsheng, Charly Chahwan, Julie M. Bailis, Tony Hunter, & Paul Russell. (2005). ATM Activation and Its Recruitment to Damaged DNA Require Binding to the C Terminus of Nbs1. Molecular and Cellular Biology. 25(13). 5363–5379. 351 indexed citations
11.
Wang, Xuelu, Xiaoqing Li, Jill Meisenhelder, et al.. (2005). Autoregulation and Homodimerization Are Involved in the Activation of the Plant Steroid Receptor BRI1. Developmental Cell. 8(6). 855–865. 218 indexed citations
12.
Watanabe, Nobumoto, et al.. (2004). M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCF β-TrCP. Proceedings of the National Academy of Sciences. 101(13). 4419–4424. 385 indexed citations
13.
Caenepeel, Sean, et al.. (2004). The mouse kinome: Discovery and comparative genomics of all mouse protein kinases. Proceedings of the National Academy of Sciences. 101(32). 11707–11712. 235 indexed citations
14.
Hunter, Tony. (2002). Tyrosine phosphorylation in cell signaling and disease.. The Keio Journal of Medicine. 51(2). 61–71. 31 indexed citations
15.
Orend, Gertraud, Tony Hunter, & Erkki Ruoslahti. (1998). Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells. Oncogene. 16(20). 2575–2583. 110 indexed citations
16.
Hunter, Tony & Bartholomew M. Sefton. (1991). Protein kinases : assays, purification, antibodies, functional analysis, cloning, and expression. Academic Press eBooks. 3 indexed citations
17.
Bull, Paulina, Kimberlin L. Morley, Merl F. Hoekstra, Tony Hunter, & Inder M. Verma. (1990). The Mouse c- rel Protein Has an N-Terminal Regulatory Domain and a C-Terminal Transcriptional Transactivation Domain. Molecular and Cellular Biology. 10(10). 5473–5485. 49 indexed citations
18.
Hunter, Tony. (1989). 6 Oncogene Products in the Cytoplasm: The Protein Kinases. Cold Spring Harbor Monograph Archive. 18. 147–173. 1 indexed citations
19.
Gould, Kathleen L. & Tony Hunter. (1988). Platelet-Derived Growth Factor Induces Multisite Phosphorylation of pp60 c- src and Increases Its Protein-Tyrosine Kinase Activity. Molecular and Cellular Biology. 8(8). 3345–3356. 44 indexed citations
20.
Cartwright, Christine A., Rabi Simantov, Paul L. Kaplan, Tony Hunter, & Walter Eckhart. (1987). Alterations in pp60 c-src Accompany Differentiation of Neurons from Rat Embryo Striatum. Molecular and Cellular Biology. 7(5). 1830–1840. 78 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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