David Komander

31.3k total citations · 16 hit papers
124 papers, 23.0k citations indexed

About

David Komander is a scholar working on Molecular Biology, Oncology and Epidemiology. According to data from OpenAlex, David Komander has authored 124 papers receiving a total of 23.0k indexed citations (citations by other indexed papers that have themselves been cited), including 116 papers in Molecular Biology, 34 papers in Oncology and 29 papers in Epidemiology. Recurrent topics in David Komander's work include Ubiquitin and proteasome pathways (89 papers), Autophagy in Disease and Therapy (28 papers) and Glycosylation and Glycoproteins Research (27 papers). David Komander is often cited by papers focused on Ubiquitin and proteasome pathways (89 papers), Autophagy in Disease and Therapy (28 papers) and Glycosylation and Glycoproteins Research (27 papers). David Komander collaborates with scholars based in United Kingdom, Australia and Germany. David Komander's co-authors include Michael Rapé, Kirby N. Swatek, Michael J. Clague, Sylvie Urbé, Tycho E.T. Mevissen, Dario R. Alessi, Yogesh Kulathu, Laura R. Pearce, Tobias Wauer and Stefan M.V. Freund and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

David Komander

120 papers receiving 22.7k citations

Hit Papers

The Ubiquitin Code 2004 2026 2011 2018 2012 2009 2016 2009 2017 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Ubiquitin Code
    2012 2.7k citations David Komander et al. profile →
  2. Breaking the chains: structure and function of the deubiquitinases
    2009 1.7k citations David Komander, Michael J. Clague et al. profile →
  3. Ubiquitin modifications
    2016 1.5k citations Kirby N. Swatek, David Komander profile →
  4. The nuts and bolts of AGC protein kinases
    2009 1.0k citations David Komander et al. profile →
  5. Mechanisms of Deubiquitinase Specificity and Regulation
    2017 771 citations David Komander et al. profile →
  6. PDK1, the master regulator of AGC kinase signal transduction
    2004 640 citations David Komander et al. profile →
  7. The emerging complexity of protein ubiquitination
    2009 630 citations David Komander profile →
  8. Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
    2009 596 citations Christoph H. Emmerich, David Komander et al. profile →
  9. Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation
    2009 595 citations Stuart Bloor, David Komander et al. profile →
  10. Breaking the chains: deubiquitylating enzyme specificity begets function
    2019 583 citations Michael J. Clague, Sylvie Urbé et al. profile →
  11. Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
    2012 538 citations David Komander et al. profile →
  12. OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis
    2013 475 citations Paul P. Geurink, Tobias Wauer et al. profile →
  13. Mechanism of phospho-ubiquitin-induced PARKIN activation
    2015 366 citations Tobias Wauer, Alexander F. Schubert et al. Nature profile →
  14. Mechanism of parkin activation by PINK1
    2018 293 citations Christina Gladkova, David Komander et al. Nature profile →
  15. Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities
    2021 245 citations Zhong Yan Gan, David Komander et al. profile →
  16. Deubiquitinases in cancer
    2023 149 citations Grant Dewson, Pieter J.A. Eichhorn et al. Nature reviews. Cancer profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
David Komander 19.2k 5.4k 5.0k 4.0k 3.1k 124 23.0k
Cecile M. Pickart 16.6k 0.9× 5.0k 0.9× 3.3k 0.7× 2.8k 0.7× 3.9k 1.3× 90 19.4k
Brenda A. Schulman 15.1k 0.8× 4.8k 0.9× 3.7k 0.7× 1.3k 0.3× 3.3k 1.1× 173 18.0k
Allan M. Weissman 13.4k 0.7× 4.2k 0.8× 2.3k 0.5× 3.7k 0.9× 3.7k 1.2× 129 18.0k
Ronald T. Hay 19.5k 1.0× 6.6k 1.2× 2.3k 0.5× 4.4k 1.1× 2.0k 0.6× 247 24.3k
Tullia Lindsten 13.2k 0.7× 4.2k 0.8× 3.8k 0.8× 8.4k 2.1× 1.9k 0.6× 98 22.8k
Raymond J. Deshaies 27.4k 1.4× 6.7k 1.2× 4.1k 0.8× 1.7k 0.4× 9.0k 2.9× 169 30.4k
George F. Vande Woude 17.2k 0.9× 6.3k 1.2× 1.9k 0.4× 2.2k 0.6× 4.1k 1.3× 247 27.8k
Avram Hershko 20.7k 1.1× 7.1k 1.3× 3.0k 0.6× 1.5k 0.4× 6.3k 2.1× 117 23.6k
Anton Berns 13.5k 0.7× 9.6k 1.8× 2.3k 0.5× 3.7k 0.9× 1.2k 0.4× 211 23.7k
Nikola P. Pavletich 25.2k 1.3× 9.2k 1.7× 1.6k 0.3× 1.9k 0.5× 3.6k 1.2× 79 30.0k

Countries citing papers authored by David Komander

Since Specialization
Citations

This map shows the geographic impact of David Komander's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Komander with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Komander more than expected).

Fields of papers citing papers by David Komander

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Komander. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Komander. The network helps show where David Komander may publish in the future.

Co-authorship network of co-authors of David Komander

This figure shows the co-authorship network connecting the top 25 collaborators of David Komander. A scholar is included among the top collaborators of David Komander based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Komander. David Komander is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Liu, Haiyin, Laura F. Dagley, Simon A. Cobbold, et al.. (2025). Major histocompatibility class II in murine antigen presenting cells is modified with a branched K63 and K11-linked ubiquitin chain. Scientific Reports. 15(1). 41884–41884.
2.
Callegari, Sylvie, Zhong Yan Gan, Toby A. Dite, et al.. (2025). Structure of human PINK1 at a mitochondrial TOM-VDAC array. Science. 388(6744). 303–310. 14 indexed citations
3.
Michel, Martin A., et al.. (2024). Secondary interactions in ubiquitin-binding domains achieve linkage or substrate specificity. Cell Reports. 43(8). 114545–114545. 4 indexed citations
4.
Kuchel, Nathan W., Bernadine G.C. Lu, Kym N. Lowes, et al.. (2024). Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape. Nature Communications. 15(1). 6219–6219. 5 indexed citations
5.
Gan, Zhong Yan, David Komander, & Sylvie Callegari. (2024). Reassessing kinetin’s effect on PINK1 and mitophagy. Autophagy. 20(11). 2596–2597. 4 indexed citations
6.
Gan, Zhong Yan, Sylvie Callegari, Thanh Ngoc Nguyen, et al.. (2024). Interaction of PINK1 with nucleotides and kinetin. Science Advances. 10(3). eadj7408–eadj7408. 7 indexed citations
7.
Gosavi, Prajakta, Mathew V. Jones, S. Sean Millard, et al.. (2024). PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4. EMBO Reports. 25(8). 3324–3347. 12 indexed citations
8.
Frank, Daniel, Maria Bergamasco, Michael J. Mlodzianoski, et al.. (2023). Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth. eLife. 12.
9.
Dewson, Grant, Pieter J.A. Eichhorn, & David Komander. (2023). Deubiquitinases in cancer. Nature reviews. Cancer. 23(12). 842–862. 149 indexed citations breakdown →
10.
Lageveen‐Kammeijer, Guinevere S. M., Bas C. Jansen, Ayşegül Sapmaz, et al.. (2023). Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes. Nature Communications. 14(1). 1661–1661. 9 indexed citations
11.
Gan, Zhong Yan, Sylvie Callegari, Simon A. Cobbold, et al.. (2021). Activation mechanism of PINK1. Nature. 602(7896). 328–335. 117 indexed citations
12.
Liu, Zikou, Laura F. Dagley, Kristy Shield‐Artin, et al.. (2021). Oligomerization‐driven MLKL ubiquitylation antagonizes necroptosis. The EMBO Journal. 40(23). e103718–e103718. 49 indexed citations
13.
Visser, Linda J., Kirby N. Swatek, Gisselle N. Medina, et al.. (2020). Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression. PLoS Pathogens. 16(7). e1008702–e1008702. 30 indexed citations
14.
Schubert, Alexander F., Paul P. Geurink, Cameron G. Roberts, et al.. (2020). Identification and characterization of diverse OTU deubiquitinases in bacteria. The EMBO Journal. 39(15). e105127–e105127. 43 indexed citations
15.
Pruneda, Jonathan N., Robert J. Bastidas, Kirby N. Swatek, et al.. (2018). A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation. Nature Microbiology. 3(12). 1377–1384. 49 indexed citations
16.
Gladkova, Christina, Alexander F. Schubert, Jane L. Wagstaff, et al.. (2017). An invisible ubiquitin conformation is required for efficient phosphorylation by PINK 1. The EMBO Journal. 36(24). 3555–3572. 49 indexed citations
17.
Thurston, Teresa L. M., Keith B. Boyle, Mark D. Allen, et al.. (2016). Recruitment of TBK 1 to cytosol‐invading Salmonella induces WIPI 2‐dependent antibacterial autophagy. The EMBO Journal. 35(16). 1779–1792. 96 indexed citations
18.
Wauer, Tobias, Kirby N. Swatek, Jane L. Wagstaff, et al.. (2014). Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis. The EMBO Journal. 34(3). 307–325. 241 indexed citations
19.
Emmerich, Christoph H., Alban Ordureau, Sam Strickson, et al.. (2013). Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. Proceedings of the National Academy of Sciences. 110(38). 15247–15252. 346 indexed citations
20.
Ye, Yu, Hartmut Scheel, Kay Hofmann, & David Komander. (2009). Dissection of USPcatalytic domains reveals five common insertion points. Molecular BioSystems. 5(12). 1797–1808. 142 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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