Axel Knebel

9.3k total citations · 2 hit papers
74 papers, 7.1k citations indexed

About

Axel Knebel is a scholar working on Molecular Biology, Oncology and Epidemiology. According to data from OpenAlex, Axel Knebel has authored 74 papers receiving a total of 7.1k indexed citations (citations by other indexed papers that have themselves been cited), including 66 papers in Molecular Biology, 22 papers in Oncology and 18 papers in Epidemiology. Recurrent topics in Axel Knebel's work include Ubiquitin and proteasome pathways (31 papers), Autophagy in Disease and Therapy (15 papers) and Peptidase Inhibition and Analysis (8 papers). Axel Knebel is often cited by papers focused on Ubiquitin and proteasome pathways (31 papers), Autophagy in Disease and Therapy (15 papers) and Peptidase Inhibition and Analysis (8 papers). Axel Knebel collaborates with scholars based in United Kingdom, Germany and United States. Axel Knebel's co-authors include Dario R. Alessi, Hans J. Rahmsdorf, Peter Herrlich, Philip Cohen, David G. Campbell, Matthias Trost, Miratul M. K. Muqit, Agne Kazlauskaite, Nicola T. Wood and Robert Gourlay and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Axel Knebel

73 papers receiving 7.1k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

2012 726 citations Helen Walden, Thomas Macartney et al. profile →
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

2014 631 citations Maria Stella Ritorto, Kay Hofmann et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Axel Knebel United Kingdom	44	5.2k	1.8k	1.2k	1.2k	1.0k	74	7.1k
Hidetaka Kosako Japan	43	5.3k 1.0×	1.6k 0.9×	787 0.6×	1.9k 1.6×	601 0.6×	118	7.6k
Helen Walden United Kingdom	34	3.9k 0.8×	1.6k 0.9×	790 0.6×	584 0.5×	950 0.9×	58	5.0k
Shengyun Fang United States	43	5.9k 1.1×	1.7k 0.9×	482 0.4×	2.5k 2.1×	1.5k 1.5×	107	8.6k
Marie W. Wooten United States	41	3.5k 0.7×	1.5k 0.8×	510 0.4×	1.1k 0.9×	579 0.6×	83	5.4k
Hideki Nishitoh Japan	37	5.3k 1.0×	1.2k 0.7×	496 0.4×	2.1k 1.7×	531 0.5×	64	8.2k
Mária Deák United Kingdom	62	11.1k 2.1×	1.2k 0.6×	1.5k 1.2×	2.4k 2.0×	1.1k 1.1×	101	14.2k
Mariusz Karbowski United States	36	7.9k 1.5×	2.2k 1.2×	741 0.6×	1.1k 0.9×	299 0.3×	62	9.5k
Shouqing Luo United Kingdom	30	3.4k 0.6×	3.6k 2.0×	752 0.6×	1.3k 1.1×	261 0.3×	52	6.4k
Mark Peggie United Kingdom	42	4.0k 0.8×	897 0.5×	339 0.3×	689 0.6×	708 0.7×	56	5.9k
Sanae M.M. Iguchi‐Ariga Japan	40	3.5k 0.7×	499 0.3×	2.2k 1.8×	626 0.5×	621 0.6×	115	6.3k

Countries citing papers authored by Axel Knebel

Since Specialization

Citations

This map shows the geographic impact of Axel Knebel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Axel Knebel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Axel Knebel more than expected).

Fields of papers citing papers by Axel Knebel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Axel Knebel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Axel Knebel. The network helps show where Axel Knebel may publish in the future.

Co-authorship network of co-authors of Axel Knebel

This figure shows the co-authorship network connecting the top 25 collaborators of Axel Knebel. A scholar is included among the top collaborators of Axel Knebel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Axel Knebel. Axel Knebel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Traynor, Ryan, Jennifer L. Moran, Odetta Antico, et al.. (2024). Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity. Cell Reports Methods. 4(2). 100712–100712. 5 indexed citations

Rehman, S.A. Abdul, Odetta Antico, Axel Knebel, et al.. (2024). Discovery and characterization of noncanonical E2-conjugating enzymes. Science Advances. 10(13). eadh0123–eadh0123. 7 indexed citations

Baston-Büst, Dunja Maria, et al.. (2024). Dead or Alive: Exploratory Analysis of Selected Apoptosis- and Autophagy-Related Proteins in Human Endometrial Stromal Cells of Fertile Females and Their Potential Role During Embryo Implantation. International Journal of Molecular Sciences. 26(1). 175–175.

Lange, Sven M., Frédéric Lamoliatte, Thomas Carroll, et al.. (2024). VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains. Nature Structural & Molecular Biology. 31(12). 1872–1887. 17 indexed citations

Waschbüsch, Dieter, Paweł Lis, Axel Knebel, et al.. (2021). Structural basis for the specificity of PPM1H phosphatase for Rab GTPases. EMBO Reports. 22(11). e52675–e52675. 16 indexed citations

Rehman, S.A. Abdul, Lee A. Armstrong, Sven M. Lange, et al.. (2021). Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Molecular Cell. 81(20). 4176–4190.e6. 29 indexed citations

Kelsall, Ian R., Jiazhen Zhang, Axel Knebel, J. Simon C. Arthur, & Philip Cohen. (2019). The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells. Proceedings of the National Academy of Sciences. 116(27). 13293–13298. 98 indexed citations

Lis, Paweł, Wondwossen M Yeshaw, Paulina S. Wawro, et al.. (2019). PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins. eLife. 8. 80 indexed citations

Cesare, Virginia De, et al.. (2018). The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway. Cell chemical biology. 25(9). 1117–1127.e4. 49 indexed citations

10.

Wood, Nicola T., Axel Knebel, Karim Rafie, et al.. (2018). Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity. Nature. 556(7701). 381–385. 208 indexed citations

11.

Strickson, Sam, Christoph H. Emmerich, Eddy T. H. Goh, et al.. (2017). Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling. Proceedings of the National Academy of Sciences. 114(17). E3481–E3489. 88 indexed citations

12.

Sonneville, Romain, Sara Priego Moreno, Axel Knebel, et al.. (2017). CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis. Nature Cell Biology. 19(5). 468–479. 81 indexed citations

13.

Kumar, Atul, Viduth K. Chaugule, Tara Condos, et al.. (2017). Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nature Structural & Molecular Biology. 24(5). 475–483. 78 indexed citations

14.

Hjerpe, Roland, John S. Bett, Matthew J. Keuss, et al.. (2016). UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. Cell. 166(4). 935–949. 221 indexed citations

15.

Kumar, Atul, Jacob D. Aguirre, Tara Condos, et al.. (2015). Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. The EMBO Journal. 34(20). 2506–2521. 155 indexed citations

16.

Ritorto, Maria Stella, Richard Ewan, Ana B. Pérez‐Oliva, et al.. (2014). Screening of DUB activity and specificity by MALDI-TOF mass spectrometry. Nature Communications. 5(1). 4763–4763. 259 indexed citations

17.

Rabut, Gwénaël, Gaëlle Le Dez, Rati Verma, et al.. (2011). The TFIIH Subunit Tfb3 Regulates Cullin Neddylation. Molecular Cell. 43(3). 488–495. 46 indexed citations

18.

Hale, Benjamin G., Axel Knebel, Catherine H. Botting, et al.. (2008). CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215. Virology. 383(1). 6–11. 68 indexed citations

19.

Groß, Steffen, Axel Knebel, Tencho Tenev, et al.. (1999). Inactivation of Protein-tyrosine Phosphatases as Mechanism of UV-induced Signal Transduction. Journal of Biological Chemistry. 274(37). 26378–26386. 140 indexed citations

20.

Wilhelm, Dagmar, Klaus Bender, Axel Knebel, & Peter Angel. (1997). The Level of Intracellular Glutathione Is a Key Regulator for the Induction of Stress-Activated Signal Transduction Pathways Including Jun N-Terminal Protein Kinases and p38 Kinase by Alkylating Agents. Molecular and Cellular Biology. 17(8). 4792–4800. 203 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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