C. Peter Downes

31.0k citations

196 papers · 26.5k indexed · 10 hit papers · h-index 77

Cell Biology top 0.05%
- Cellular transport and secretion 60
Molecular Biology top 0.05%
- Protein Kinase Regulation and GTPase Signaling 99
- PI3K/AKT/mTOR signaling in cancer 53
- Metabolism, Diabetes, and Cancer 13
- Lipid Membrane Structure and Behavior 13
Physiology top 0.1%
- Erythrocyte Function and Pathophysiology 15
Cellular and Molecular Neuroscience top 0.2%
Genetics top 0.5%
- Coagulation, Bradykinin, Polyphosphates, and Angioedema 10
Surgery
- Pancreatic function and diabetes 30

Co-authors: Michael J. Berridge Michael R. Hanley Nicholas R. Leslie Dario R. Alessi Robert H. Michell Robin F. Irvine Alexander Gray Stephen R. James
Cited by: Cell Biology Molecular Biology Physiology
Journals: Biochemical Journal (69 papers)Journal of Biological Chemistry (29 papers)Biochemical Society Transactions (16 papers)
Partner nations: United Kingdom United States Canada

In The Last Decade

C. Peter Downes

196 papers receiving 25.8k citations

Hit Papers

10 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2004 The Journal of Cell Biology
1998 Proceedings of the National Academy of Sciences
1997 Current Biology
1989 Cell
1988 Nature
1983 Biochemical Journal
1983 Biochemical Journal
1982 Biochemical Journal
1982 Biochemical Journal
1981 Biochemical Journal

Peers

Countries citing papers authored by C. Peter Downes

Since Specialization

Citations

This map shows the geographic impact of C. Peter Downes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Peter Downes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Peter Downes more than expected).

Fields of papers citing papers by C. Peter Downes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Peter Downes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Peter Downes. The network helps show where C. Peter Downes may publish in the future.

Co-authorship network

The 25 scholars most cited alongside C. Peter Downes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with C. Peter Downes Line = papers co-authored together C. Peter Downes links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	PtdIns(3,4,5)P3-Dependent and -Independent Roles for PTEN in the Control of Cell Migration Current Biology ·Nicholas R. Leslie,Xuesong Yang,C. Peter Downes,Cornelis J. Weijer	2007	160
2	Stimulation of PI 3-kinase signaling via inhibition of the tumor suppressor phosphatase, PTEN Advances in Enzyme Regulation ·C. Peter Downes,Sarah H. Ross,Hélène Maccario,Nevin M. Perera,L. S. P. Davidson,Nicholas R. Leslie	2006	45
3	PTEN M-CBR3, a Versatile and Selective Regulator of Inositol 1,3,4,5,6-Pentakisphosphate (Ins(1,3,4,5,6)P5) Journal of Biological Chemistry ·Riyan Dano Prasetyo,Dineli Pathirana,Nicholas R. Leslie,Rosemary G. Clarke,Alisa Miller,C. Peter Downes,Stephen T. Safrany	2004	26
4	Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts Analytical Biochemistry ·Alexander Gray,Henric Olsson,Ian H. Batty,Maryna Cherkashyna-Hubarenko,C. Peter Downes	2003	128
5	A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation The Journal of Experimental Medicine ·Elizabeth Clayton,Giuseppe Bardi,Sarah E. Bell,David Chantry,C. Peter Downes,Alexander Gray,Lisa A. Humphries,David J. Rawlings,Nurnabilah Zainuddin,Elena Vigorito,Martin Turner	2002	364
6	Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN Current Biology ·Lisa Patel,Ian Pass,H. B. Heng,C. Peter Downes,Stephen A. Smith,Colin H. Macphee	2001	312
7	Differential coupling of G‐protein‐linked receptors to Ca²⁺ mobilization through inositol(1,4,5)trisphosphate or ryanodine receptors in cerebellar granule cells in primary culture European Journal of Neuroscience ·Shi-Hai 世海 Dong 董,Marκ McLaughlin,C. Peter Downes,David G. Nicholls	1999	18
8	The role of PI 3-kinase in insulin action Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·Dario R. Alessi,C. Peter Downes	1998	185
9	Lipid signalling Current Biology ·C. Peter Downes,A Currie	1998	9
10	Purification and Characterization of Gβγ-responsive Phosphoinositide 3-Kinases from Pig Platelet Cytosol Journal of Biological Chemistry ·Xiuwen Tang,C. Peter Downes	1997	68
11	A Novel, Rapid, and Highly Sensitive Mass Assay for Phosphatidylinositol 3,4,5-Trisphosphate (PtdIns(3,4,5)P3) and Its Application to Measure Insulin-stimulated PtdIns(3,4,5)P3 Production in Rat Skeletal Muscle in Vivo Journal of Biological Chemistry ·Jeroen van der Kaay,Ian H. Batty,Darren A.E. Cross,P. Watt,C. Peter Downes	1997	37
12	Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bαbreakdown → Current Biology ·Dario R. Alessi,Stephen R. James,C. Peter Downes,Andrew B. Holmes,Piers R. J. Gaffney,Colin B. Reese,Philip P. Cohen	1997	2349
13	The lipid transfer activity of phosphatidylinositol transfer protein is sufficient to account for enhanced phospholipase C activity in turkey erythrocyte ghosts Current Biology ·A Currie,V. N. Katsap,C. Peter Downes	1997	30
14	Association of a phosphatidylinositol-specific 3-kinase with a human trans -Golgi network resident protein Current Biology ·D. Mark Hickinson,John M. Lucocq,Mhairi C. Towler,Cristina Arboleda,Joanna L. James,Sarah James,C. Peter Downes,Sreenivasan Ponnambalam	1997	24
15	Phosphotyrosine Residues in the Nerve‐Growth‐Factor Receptor (Trk‐A) European Journal of Biochemistry ·Ruth Baxter,Philip Cohen,Axel Obermeier,Axel Ullrich,C. Peter Downes,Yair N. Doza	1995	47
16	Involvement of Calcium Influx in Muscarinic Cholinergic Regulation of Phospholipase C in Cerebellar Granule Cells Journal of Neurochemistry ·Shi-Hai 世海 Dong 董,David G. Nicholls,C. Peter Downes	1994	31
17	Chemotactic Peptides but not Macrophage Colony Stimulating Factor Effect the Synthesis of Inositol Lipids in Macrophages Growth Factors ·KLAUS KRAEMER,Colin H. Macphee,C. Peter Downes,Anthony D. Whetton	1991	2
18	Phosphoinositide 3-kinase: A new effector in signal transduction? Cellular Signalling ·C. Peter Downes,محمد عهد الدالي	1991	148
19	Inositol lipids in cell signalling. Academic Press eBooks ·Robert H. Michell,Alan H. Drummond,C. Peter Downes	1989	182
20	Receptor and G-protein-dependent regulation of turkey erythrocyte phosphoinositidase C Philosophical transactions of the Royal Society of London. Series B, Biological sciences ·C. Peter Downes,Christopher P. Berrie,Phillip T. Hawkins,Len Stephens,José L. Boyer,T K Harden	1988	6

About C. Peter Downes

C. Peter Downes is a scholar working on Cell Biology, Molecular Biology and Physiology, having authored 196 papers that have together received 26.5k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (99 papers), Cellular transport and secretion (60 papers), PI3K/AKT/mTOR signaling in cancer (53 papers), Pancreatic function and diabetes (30 papers), Erythrocyte Function and Pathophysiology (15 papers), Metabolism, Diabetes, and Cancer (13 papers), Lipid Membrane Structure and Behavior (13 papers) and Coagulation, Bradykinin, Polyphosphates, and Angioedema (10 papers). The work is most often cited by research in Cell Biology (5.5k citations), Molecular Biology (19.3k citations) and Physiology (1.0k citations). C. Peter Downes has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Michael J. Berridge, Michael R. Hanley, Nicholas R. Leslie, Dario R. Alessi, Robert H. Michell, Robin F. Irvine, Alexander Gray, Stephen R. James, Ian H. Batty and Piers R. J. Gaffney. Their work appears in journals such as Biochemical Journal, Journal of Biological Chemistry, Biochemical Society Transactions, Current Biology and Journal of Neurochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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