Leif S. Ludwig

5.3k citations

36 papers · 1.7k indexed · 1 hit paper · h-index 18

Molecular Biology top 10%
Immunology top 5%
Cancer Research top 5%
Hematology top 5%
Genetics top 5%

Co-authors: Caleb A. Lareau Vijay G. Sankaran Aviv Regev Jacob C. Ulirsch Martin J. Aryee Jason D. Buenrostro Christoph Muus Nir Hacohen
Topics: Single-cell and spatial transcriptomics (15 papers)Cancer Genomics and Diagnostics (12 papers)RNA modifications and cancer (7 papers)
Cited by: Cancer Research Immunology Hematology
Journals: Nature New England Journal of Medicine Cell
Partner nations: United States Germany United Kingdom

In The Last Decade

Leif S. Ludwig

35 papers receiving 1.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics

2019 325 citations Leif S. Ludwig, Caleb A. Lareau et al. Cell profile →

Peers

Countries citing papers authored by Leif S. Ludwig

Since Specialization

Citations

This map shows the geographic impact of Leif S. Ludwig's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leif S. Ludwig with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leif S. Ludwig more than expected).

Fields of papers citing papers by Leif S. Ludwig

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leif S. Ludwig. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leif S. Ludwig. The network helps show where Leif S. Ludwig may publish in the future.

Co-authorship network of co-authors of Leif S. Ludwig

This figure shows the co-authorship network connecting the top 25 collaborators of Leif S. Ludwig. A scholar is included among the top collaborators of Leif S. Ludwig based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leif S. Ludwig. Leif S. Ludwig is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Dynamics of clonal hematopoiesis and cellular responses to stress-induced toxicity in autologous stem cell transplantation 2025 ·Leukemia ·(unknown),Raphael Hablesreiter,Friederike Christen,(unknown),Coral Fustero‐Torre,(unknown),(unknown),Lena Nitsch,(unknown),(unknown),Lars Bullinger,Leif S. Ludwig,Paulina M. Strzelecka,Frédérik Damm	0
2	Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing 2025 ·Nature Genetics ·(unknown),Robert R. Stickels,(unknown),(unknown),(unknown),(unknown),Catherine Snopkowski,Kenny Kwok Hei Yu,(unknown),Viviane Tabar,Brooke E. Howitt,Leif S. Ludwig,Ronan Chaligné,Ansuman T. Satpathy,Caleb A. Lareau	7
3	Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3 2025 ·Nature ·Kelvin Y. Chen,Tatsuya Kibayashi,(unknown),(unknown),(unknown),Norihisa Mikami,Yusuke Takeshima,Kenji Ichiyama,Ryusuke Omiya,Leif S. Ludwig,Kunihiro Hattori,Shimon Sakaguchi	5
4	Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility 2023 ·Nature Protocols ·Caleb A. Lareau,Vincent Liu,Christoph Muus,Samantha D. Praktiknjo,Lena Nitsch,(unknown),Katalin Sándor,Yajie Yin,(unknown),Karin Pelka,Ansuman T. Satpathy,Aviv Regev,Vijay G. Sankaran,Leif S. Ludwig	33
5	Single-cell multi-omics and lineage tracing to dissect cell fate decision-making 2023 ·Stem Cell Reports ·Laleh Haghverdi,Leif S. Ludwig	16
6	Mitochondrial DNA Mutations as Natural Barcodes for Lineage Tracing of Murine Tumor Models 2022 ·Cancer Research ·Livius Penter,Elisa ten Hacken,Jackson Southard,Caleb A. Lareau,Leif S. Ludwig,Shuqiang Li,Donna Neuberg,Kenneth J. Livak,Catherine J. Wu	6
7	Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations 2022 ·Nature Biotechnology ·Tyler E. Miller,Caleb A. Lareau,Julia A. Verga,Erica A. K. DePasquale,Vincent Liu,(unknown),Katalin Sándor,Yajie Yin,Leif S. Ludwig,Chadi A. El Farran,Duncan M. Morgan,Ansuman T. Satpathy,Gabriel K. Griffin,Andrew A. Lane,J. Christopher Love,B Bernstein,Vijay G. Sankaran,Peter van Galen	74
8	Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History 2021 ·Cancer Discovery ·Livius Penter,Satyen H. Gohil,Caleb A. Lareau,Leif S. Ludwig,Erin M. Parry,Teddy Huang,Shuqiang Li,Wandi Zhang,Dimitri Livitz,Ignaty Leshchiner,Laxmi Parida,Gad Getz,Laura Z. Rassenti,Thomas J. Kipps,Jennifer R. Brown,Matthew S. Davids,Donna Neuberg,Kenneth J. Livak,Vijay G. Sankaran,Catherine J. Wu	45
9	Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript 2021 ·The Journal of Experimental Medicine ·Lara Wahlster,Jeffrey M. Verboon,Leif S. Ludwig,(unknown),Wendy Luo,(unknown),Richard A. Voit,Ryan L. Collins,Kiran Garimella,Maura Costello,Katherine R. Chao,Julia K. Goodrich,Stephanie DiTroia,Anne O’Donnell‐Luria,Michael E. Talkowski,Alan D. Michelson,Alan Cantor,Vijay G. Sankaran	10
10	Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC 2021 ·Nature Biotechnology ·Evgenij Fiškin,Caleb A. Lareau,Leif S. Ludwig,Gökçen Eraslan,Feimei Liu,Aaron M. Ring,Ramnik J. Xavier,Aviv Regev	51
11	Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells 2020 ·New England Journal of Medicine ·Melissa Walker,Caleb A. Lareau,Leif S. Ludwig,Amel Karaa,Vijay G. Sankaran,Aviv Regev,Vamsi K. Mootha	60
12	Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling 2020 ·Nature Biotechnology ·Caleb A. Lareau,Leif S. Ludwig,Christoph Muus,Satyen H. Gohil,Tongtong Zhao,Zachary Chiang,Karin Pelka,Jeffrey M. Verboon,Wendy Luo,Elena Christian,Daniel Rosebrock,Gad Getz,Genevieve M. Boland,Fei Chen,Jason D. Buenrostro,Nir Hacohen,Catherine J. Wu,Martin J. Aryee,Aviv Regev,Vijay G. Sankaran	178
13	Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features 2020 ·Nature Communications ·John Ray,Carl G. de Boer,Charles P. Fulco,Caleb A. Lareau,Masahiro Kanai,Jacob C. Ulirsch,Ryan Tewhey,Leif S. Ludwig,Steven K. Reilly,Drew T. Bergman,J Engreitz,Robbyn Issner,Hilary K. Finucane,Eric S. Lander,Aviv Regev,Nir Hacohen	50
14	Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation 2019 ·The Journal of Experimental Medicine ·Nour J. Abdulhay,Claudia Fiorini,Jeffrey M. Verboon,Leif S. Ludwig,Jacob C. Ulirsch,Barbara Zieger,Caleb A. Lareau,Xiaoli Mi,Anindita Roy,Esther A. Obeng,Miriam Erlacher,Namrata Gupta,Stacey Gabriel,Benjamin L. Ebert,Charlotte M. Niemeyer,Rami Khoriaty,Philip Ancliff,Hanna T. Gazda,Marcin W. Włodarski,Vijay G. Sankaran	23
15	Interrogation of human hematopoiesis at single-cell and single-variant resolution 2019 ·Nature Genetics ·Jacob C. Ulirsch,Caleb A. Lareau,Erik L. Bao,Leif S. Ludwig,Michael H. Guo,Christian Benner,Ansuman T. Satpathy,Vinay K. Kartha,Rany M. Salem,Joel N. Hirschhorn,Hilary K. Finucane,Martin J. Aryee,Jason D. Buenrostro,Vijay G. Sankaran	102
16	Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking 2019 ·Blood Advances ·Caleb A. Lareau,Leif S. Ludwig,Vijay G. Sankaran	11
17	Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis 2019 ·eLife ·Satish K. Nandakumar,Sean McFarland,(unknown),Caleb A. Lareau,Jacob C. Ulirsch,Leif S. Ludwig,Gaurav Agarwal,J Engreitz,Bartlomiej Przychodzen,Marie McConkey,Glenn S. Cowley,John G. Doench,Jaroslaw P. Maciejewski,Benjamin L. Ebert,David E. Root,Vijay G. Sankaran	12
18	Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomicsbreakdown → 2019 ·Cell ·Leif S. Ludwig,Caleb A. Lareau,Jacob C. Ulirsch,Elena Christian,Christoph Muus,(unknown),Karin Pelka,William Ge,Yaara Oren,Alison Brack,Travis Law,Christopher Rodman,Jonathan Chen,Genevieve M. Boland,Nir Hacohen,Orit Rozenblatt–Rosen,Martin J. Aryee,Jason D. Buenrostro,Aviv Regev,Vijay G. Sankaran	325
19	Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis 2019 ·Cell Reports ·Leif S. Ludwig,Caleb A. Lareau,Erik L. Bao,Satish K. Nandakumar,Christoph Muus,Jacob C. Ulirsch,Kaitavjeet Chowdhary,Jason D. Buenrostro,Narla Mohandas,Xiuli An,Martin J. Aryee,Aviv Regev,Vijay G. Sankaran	93
20	Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells 2015 ·Cell stem cell ·(unknown),Claudia Fiorini,Aoi Wakabayashi,Leif S. Ludwig,Rany M. Salem,Chintan Jobaliya,(unknown),Jacob C. Ulirsch,Liang Ge,Orna Steinberg‐Shemer,Michael H. Guo,Tōnu Esko,Wei Tong,Carlo Brugnara,Joel N. Hirschhorn,Mitchell J. Weiss,Leonard I. Zon,Stella T. Chou,Deborah L. French,(unknown),Vijay G. Sankaran	62

About Leif S. Ludwig

Leif S. Ludwig is a scholar working on Genetics, Cancer Research and Immunology, having authored 36 papers that have together received 1.7k indexed citations. Recurring topics across this work include Single-cell and spatial transcriptomics (15 papers), Cancer Genomics and Diagnostics (12 papers) and RNA modifications and cancer (7 papers). The work is most often cited by research in Cancer Research (362 citations), Immunology (437 citations) and Hematology (203 citations). Leif S. Ludwig has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Caleb A. Lareau, Vijay G. Sankaran, Aviv Regev, Jacob C. Ulirsch, Martin J. Aryee, Jason D. Buenrostro, Christoph Muus, Nir Hacohen, Karin Pelka and Elena Christian. Their work appears in journals such as Nature, New England Journal of Medicine and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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