Martin J. Aryee

44.7k citations

92 papers · 17.9k indexed · 17 hit papers · h-index 50

Molecular Biology top 0.1%
Genetics top 0.2%
Cancer Research top 1%
Pediatrics, Perinatology and Child Health top 1%
Pulmonary and Respiratory Medicine top 2%

Co-authors: J. Keith Joung Andrew P. Feinberg Rafael A. Irizarry Shengdar Q. Tsai Kasper D. Hansen Christine Ladd‐Acosta Nathalie T. Nguyen Andrew E. Jaffe
Topics: Epigenetics and DNA Methylation (34 papers)CRISPR and Genetic Engineering (19 papers)Genomics and Chromatin Dynamics (15 papers)
Cited by: Business and International Management Aging Molecular Biology
Journals: Nature Science Cell
Partner nations: United States Sweden Switzerland

In The Last Decade

Martin J. Aryee

91 papers receiving 17.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

2014 2.5k citations Martin J. Aryee, Andrew E. Jaffe et al. Bioinformatics profile →
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

2014 1.6k citations Shengdar Q. Tsai, Zongli Zheng et al. Nature Biotechnology profile →
Engineered CRISPR-Cas9 nucleases with altered PAM specificities

2015 1.3k citations Shengdar Q. Tsai, Ved V. Topkar et al. profile →
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

2009 867 citations Martin J. Aryee, Rafael A. Irizarry et al. Nature Genetics profile →
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

2014 749 citations Shengdar Q. Tsai, Martin J. Aryee et al. Nature Biotechnology profile →
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

2013 662 citations Yun Liu, Martin J. Aryee et al. Nature Biotechnology profile →
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets

2017 547 citations Shengdar Q. Tsai, Nathalie T. Nguyen et al. Nature Methods profile →
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells

2016 509 citations Shengdar Q. Tsai, Nathalie T. Nguyen et al. Nature Biotechnology profile →
Global Causes of Diarrheal Disease Mortality in Children <5 Years of Age: A Systematic Review

2013 489 citations Martin J. Aryee et al. profile →
Comprehensive methylome map of lineage commitment from haematopoietic progenitors

2010 467 citations Hwa-Jin Lee, Martin J. Aryee et al. profile →
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

2019 462 citations Sowmya Iyer, Caleb A. Lareau et al. profile →
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

2019 453 citations Luca Pinello, Martin J. Aryee et al. Nature Biotechnology profile →
Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation

2018 397 citations Jason D. Buenrostro, Caleb A. Lareau et al. profile →
Diarrhea incidence in low- and middle-income countries in 1990 and 2010: a systematic review

2012 369 citations Martin J. Aryee et al. profile →
Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics

2019 325 citations Leif S. Ludwig, Caleb A. Lareau et al. profile →
High levels of AAV vector integration into CRISPR-induced DNA breaks

2019 289 citations Shengdar Q. Tsai, Martin Ingelsson et al. Nature Communications profile →
Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model

2019 257 citations Martin J. Aryee, Rafael A. Irizarry et al. profile →

Peers

Countries citing papers authored by Martin J. Aryee

Since Specialization

Citations

This map shows the geographic impact of Martin J. Aryee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Martin J. Aryee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Martin J. Aryee more than expected).

Fields of papers citing papers by Martin J. Aryee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Martin J. Aryee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Martin J. Aryee. The network helps show where Martin J. Aryee may publish in the future.

Co-authorship network of co-authors of Martin J. Aryee

This figure shows the co-authorship network connecting the top 25 collaborators of Martin J. Aryee. A scholar is included among the top collaborators of Martin J. Aryee based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Martin J. Aryee. Martin J. Aryee is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Risk of bleeding in patients with essential thrombocythemia and extreme thrombocytosis 2024 ·Blood Advances ·(unknown),Robert Redd,(unknown),Martin J. Aryee,Anna E. Marneth,(unknown),(unknown),(unknown),Lachelle D. Weeks,Maximilian Stahl,Daniel J. DeAngelo,R. Coleman Lindsley,Marlise R. Luskin,Gabriela Hobbs,Joan How	3
2	Spatial transcriptomics reveals distinct tissue niches linked with steroid responsiveness in acute gastrointestinal GVHD 2023 ·Blood ·(unknown),Michael J. Raabe,(unknown),(unknown),Chenyue Lu,Vikram Deshpande,Linda T. Nieman,Martin J. Aryee,Yi‐Bin Chen,David T. Ting,Zachariah DeFilipp	0
3	Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity 2023 ·Science Advances ·Rajendran Sanalkumar,Rui Dong,(unknown),Yu‐Hang Xing,Sowmya Iyer,Igor Letovanec,Stefano La Rosa,Giovanna Finzi,(unknown),Roberto Papait,Ivan Chebib,G. Petur Nielsen,Raffaele Renella,Gregory M. Coté,Edwin Choy,Martin J. Aryee,Kimberly Stegmaier,Ivan Stamenkovic,Miguel N. Rivera,Nicolò Riggi	17
4	CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer’s disease PSEN1 M146L mutation 2022 ·Molecular Therapy — Nucleic Acids ·(unknown),(unknown),(unknown),(unknown),Sarah M. Fayad,Daniel Y. Kim,Karl Petri,Martin J. Aryee,(unknown),Bence György,Vilmantas Giedraitis,J. Keith Joung,Vikram Pattanayak,Magnus Essand,Anna Erlandsson,Oksana Berezovska,Martin Ingelsson	28
5	Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery 2022 ·Nature Communications ·(unknown),(unknown),Heejin Roh,(unknown),Corin Wagen,Eric S. Zhou,Sarah E. Johnstone,Martin J. Aryee,Brian B. Liau	17
6	Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seq 2021 ·Nature Protocols ·Nikolay Malinin,GaHyun Lee,Cícera R. Lazzarotto,Yichao Li,Zongli Zheng,Nathalie T. Nguyen,Matthew Liebers,Ved V. Topkar,A. John Iafrate,Long P. Le,Martin J. Aryee,J. Keith Joung,Shengdar Q. Tsai	46
7	Screening human lung cancer with predictive models of serum magnetic resonance spectroscopy metabolomics 2021 ·Proceedings of the National Academy of Sciences ·(unknown),(unknown),Yannick Berker,(unknown),Lindsey A. Vandergrift,Piet Habbel,Johannes Nowak,Matthias Taupitz,Martin J. Aryee,Mari Mino–Kenudson,David C. Christiani,Leo L. Cheng	23
8	Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling 2020 ·Nature Biotechnology ·Caleb A. Lareau,Leif S. Ludwig,Christoph Muus,Satyen H. Gohil,Tongtong Zhao,Zachary Chiang,Karin Pelka,Jeffrey M. Verboon,Wendy Luo,Elena Christian,Daniel Rosebrock,Gad Getz,Genevieve M. Boland,Fei Chen,Jason D. Buenrostro,Nir Hacohen,Catherine J. Wu,Martin J. Aryee,Aviv Regev,Vijay G. Sankaran	178
9	Interrogation of human hematopoiesis at single-cell and single-variant resolution 2019 ·Nature Genetics ·Jacob C. Ulirsch,Caleb A. Lareau,Erik L. Bao,Leif S. Ludwig,Michael H. Guo,Christian Benner,Ansuman T. Satpathy,Vinay K. Kartha,Rany M. Salem,Joel N. Hirschhorn,Hilary K. Finucane,Martin J. Aryee,Jason D. Buenrostro,Vijay G. Sankaran	102
10	Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility 2019 ·Nature Biotechnology ·Caleb A. Lareau,Fabiana M. Duarte,Jennifer Chew,Vinay K. Kartha,(unknown),Andrew Kohlway,Dmitry Pokholok,Martin J. Aryee,Frank J. Steemers,Ronald Lebofsky,Jason D. Buenrostro	279
11	Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks 2018 ·Nature Communications ·Richard Pelikan,Jennifer A. Kelly,Yao Fu,Caleb A. Lareau,Kandice L. Tessneer,Graham B. Wiley,(unknown),Stuart B. Glenn,John B. Harley,Joel M. Guthridge,Judith A. James,Martin J. Aryee,Courtney G. Montgomery,Patrick M. Gaffney	50
12	diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data 2017 ·Bioinformatics ·Caleb A. Lareau,Martin J. Aryee	47
13	Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing 2017 ·The Journal of Experimental Medicine ·Qin Tang,Sowmya Iyer,Riadh Lobbardi,John C. Moore,Huidong Chen,Caleb A. Lareau,Christine Hebert,McKenzie Shaw,Cyril Neftel,Mario L. Suvà,Craig J. Ceol,André Bernards,Martin J. Aryee,Luca Pinello,Iain A. Drummond,David M. Langenau	141
14	Single-Cell Joint Methylomics and Transcriptomics Define the Epigenetic Evolution and Lineage Histories of Chronic Lymphocytic Leukemia 2017 ·Blood ·Ronan Chaligné,Federico Gaiti,Steven Kothen-Hill,Hongcang Gu,(unknown),Rafael Schulman,(unknown),Evan Biederstedt,Lili Wang,Martin J. Aryee,Andreas Gnirke,Catherine J. Wu,Alexander Meissner,Dan A. Landau	1
15	High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis 2016 ·Genome Medicine ·David Gómez-Cabrero,Malin Almgren,Louise K. Sjöholm,Aase Hensvold,(unknown),Rakel Tryggvadóttir,Juha Kere,Annika Scheynius,Nathalie Acevedo,Lovisa E. Reinius,Margaret A. Taub,Carolina Montaño,Martin J. Aryee,Jason I. Feinberg,Andrew P. Feinberg,Jesper Tegnér,Lars Klareskog,Anca I. Catrina,Tomas J. Ekström	22
16	Lysine Demethylase KDM4A Associates with Translation Machinery and Regulates Protein Synthesis 2015 ·Cancer Discovery ·Capucine Van Rechem,Joshua C. Black,Myriam Boukhali,Martin J. Aryee,S. Gräslund,Wilhelm Haas,Cyril H. Benes,Johnathan R. Whetstine	51
17	Epigenome-wide association studies without the need for cell-type composition 2014 ·Nature Methods ·James Zou,Christoph Lippert,David Heckerman,Martin J. Aryee,Jennifer Listgarten	147
18	GeMes, Clusters of DNA Methylation under Genetic Control, Can Inform Genetic and Epigenetic Analysis of Disease 2014 ·The American Journal of Human Genetics ·Yun Liu,Xin Li,Martin J. Aryee,Tomas J. Ekström,Leonid Padyukov,Lars Klareskog,Amy R. Vandiver,Ann Zenobia Moore,Toshiko Tanaka,Luigi Ferrucci,M. Daniele Fallin,Andrew P. Feinberg	72
19	DNA methylation shows genome-wide association ofNFIX,RAPGEF2andMSRB3with gestational age at birth 2012 ·International Journal of Epidemiology ·Hwa-Jin Lee,Andrew E. Jaffe,Jason I. Feinberg,Rakel Tryggvadóttir,Shannon Brown,Carolina Montaño,Martin J. Aryee,Rafael A. Irizarry,Julie B. Herbstman,Frank R. Witter,Lynn R. Goldman,Andrew P. Feinberg,M. Daniele Fallin	55
20	Accurate genome-scale percentage DNA methylation estimates from microarray data 2010 ·Biostatistics ·Martin J. Aryee,Zhijin Wu,Christine Ladd‐Acosta,Brian R. Herb,Andrew P. Feinberg,Srinivasan Yegnasubramanian,Rafael A. Irizarry	58

About Martin J. Aryee

Martin J. Aryee is a scholar working on Business and International Management, Molecular Biology and Cancer Research, having authored 92 papers that have together received 17.9k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (34 papers), CRISPR and Genetic Engineering (19 papers) and Genomics and Chromatin Dynamics (15 papers). The work is most often cited by research in Business and International Management (853 citations), Aging (586 citations) and Molecular Biology (14.7k citations). Martin J. Aryee has collaborated with scholars based in United States, Sweden and Switzerland. Frequent co-authors include J. Keith Joung, Andrew P. Feinberg, Rafael A. Irizarry, Shengdar Q. Tsai, Kasper D. Hansen, Christine Ladd‐Acosta, Nathalie T. Nguyen, Andrew E. Jaffe, Héctor Corrada Bravo and Ved V. Topkar. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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