Kay Hofmann

51.8k total citations · 20 hit papers
311 papers, 40.5k citations indexed

About

Kay Hofmann is a scholar working on Molecular Biology, Cell Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Kay Hofmann has authored 311 papers receiving a total of 40.5k indexed citations (citations by other indexed papers that have themselves been cited), including 239 papers in Molecular Biology, 78 papers in Cell Biology and 35 papers in Cellular and Molecular Neuroscience. Recurrent topics in Kay Hofmann's work include Ubiquitin and proteasome pathways (94 papers), Endoplasmic Reticulum Stress and Disease (33 papers) and DNA Repair Mechanisms (24 papers). Kay Hofmann is often cited by papers focused on Ubiquitin and proteasome pathways (94 papers), Endoplasmic Reticulum Stress and Disease (33 papers) and DNA Repair Mechanisms (24 papers). Kay Hofmann collaborates with scholars based in Germany, United States and Switzerland. Kay Hofmann's co-authors include Jürg Tschopp, W Stoffel, Amos Bairoch, Philip Bucher, Philipp Bücher, Pascal Schneider, Kim Burns, Margot Thome, Laurent Falquet and Etienne Meylan and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Kay Hofmann

299 papers receiving 39.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inhibition of death receptor signals by cellular FLIP

1997 2.1k citations Kay Hofmann et al. Nature profile →
Tmbase-A database of membrane spanning protein segments

1993 2.1k citations Kay Hofmann et al. profile →
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

2005 2.0k citations Kay Hofmann et al. Nature profile →
The PROSITE database, its status in 1997

1997 1.5k citations Kay Hofmann et al. profile →
SKP1 Connects Cell Cycle Regulators to the Ubiquitin Proteolysis Machinery through a Novel Motif, the F-Box

1996 1.2k citations Kay Hofmann et al. profile →
BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth

1999 1.1k citations Kay Hofmann et al. profile →
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1997 1.1k citations Kay Hofmann et al. Nature profile →
Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.

1992 1.0k citations Kay Hofmann et al. profile →
The PROSITE database, its status in 1999

1999 936 citations Kay Hofmann et al. profile →
RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation

2004 674 citations Kay Hofmann et al. profile →
Arac/XylS family of transcriptional regulators

1997 662 citations Kay Hofmann et al. profile →
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

2014 631 citations Kay Hofmann, Axel Knebel et al. profile →
A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins

1997 617 citations Kay Hofmann et al. profile →
TRAIL Receptors 1 (DR4) and 2 (DR5) Signal FADD-Dependent Apoptosis and Activate NF-κB

1997 605 citations Kay Hofmann et al. profile →
Ubiquitin-Binding Domains in Y-Family Polymerases Regulate Translesion Synthesis

2005 587 citations Kay Hofmann, Ivan Đikić et al. Science profile →
Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion

1997 553 citations Kay Hofmann et al. Nature profile →
Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair

2007 552 citations Kay Hofmann, Alan D. D’Andrea et al. profile →
Proteasome subunit Rpn13 is a novel ubiquitin receptor

2008 514 citations Kay Hofmann, Ivan Đikić et al. Nature profile →
Selective autophagy: ubiquitin-mediated recognition and beyond

2010 506 citations Kay Hofmann et al. profile →
MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

2016 289 citations Kay Hofmann et al. Molecular Cell profile →

Peers

Countries citing papers authored by Kay Hofmann

Since Specialization

Citations

This map shows the geographic impact of Kay Hofmann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kay Hofmann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kay Hofmann more than expected).

Fields of papers citing papers by Kay Hofmann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kay Hofmann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kay Hofmann. The network helps show where Kay Hofmann may publish in the future.

Co-authorship network of co-authors of Kay Hofmann

This figure shows the co-authorship network connecting the top 25 collaborators of Kay Hofmann. A scholar is included among the top collaborators of Kay Hofmann based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kay Hofmann. Kay Hofmann is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A family of bacterial Josephin-like deubiquitinases with an irreversible cleavage mode 2025 ·Molecular Cell ·Thomas Hermanns, (unknown), (unknown), (unknown), Monique P. C. Mulder, Ulrich Baumann, Kay Hofmann	3
2	ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway 2024 ·Life Science Alliance ·(unknown), Sebastian Kallabis, (unknown), (unknown), (unknown), (unknown), (unknown), Susanne Brodesser, Stefan Müller, Kay Hofmann, Marcus Krüger, Elena I. Rugarli	2
3	Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis 2023 ·Nature Communications ·(unknown), Thomas Hermanns, (unknown), (unknown), (unknown), Vera Kozjak‐Pavlovic, Ulrich Baumann, Kay Hofmann	4
4	Identification and characterization of diverse OTU deubiquitinases in bacteria 2020 ·The EMBO Journal ·Alexander F. Schubert, (unknown), (unknown), Paul P. Geurink, Cameron G. Roberts, (unknown), Lauren N. Miller, Huib Ovaa, Kay Hofmann, Jonathan N. Pruneda, David Komander	43
5	An evolutionary approach to systematic discovery of novel deubiquitinases, applied to Legionella 2020 ·Life Science Alliance ·Thomas Hermanns, (unknown), (unknown), Robert Vogt, Michael Lammers, Kay Hofmann	21
6	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity 2018 ·Nature ·(unknown), Nicola T. Wood, Axel Knebel, Karim Rafie, Mathew Stanley, Peter D. Mabbitt, Ramasubramanian Sundaramoorthy, Kay Hofmann, Daan M. F. van Aalten, Satpal Virdee	208
7	Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links 2015 ·Science ·Markus Räschle, Godelieve Smeenk, (unknown), (unknown), Yasuyoshi Oka, Marco Y. Hein, Nagarjuna Nagaraj, David T. Long, Johannes C. Walter, Kay Hofmann, Zuzana Štorchová, Jürgen Cox, Simon Bekker‐Jensen, Niels Mailand, Matthias Mann	170
8	A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly 2015 ·Nature Structural & Molecular Biology ·Nathalie Eisenhardt, Viduth K. Chaugule, Stefanie Koidl, Mathias Droescher, (unknown), (unknown), Päivi Sutinen, Susumu Y. Imanishi, Kay Hofmann, Jorma J. Palvimo, Andrea Pichler	87
9	The Human Selenoprotein VCP-interacting Membrane Protein (VIMP) Is Non-globular and Harbors a Reductase Function in an Intrinsically Disordered Region 2012 ·Journal of Biological Chemistry ·(unknown), (unknown), Andrea Vala, (unknown), Linda Johansson, Jakob R. Winther, Kay Hofmann, Kaare Teilum, Lars Ellgaard	40
10	Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI 2011 ·Molecular Cell ·George‐Lucian Moldovan, Donniphat Dejsuphong, Mark I.R. Petalcorin, Kay Hofmann, Shunichi Takeda, Simon J. Boulton, Alan D. D’Andrea	183
11	Dissection of USPcatalytic domains reveals five common insertion points 2009 ·Molecular BioSystems ·Yu Ye, Hartmut Scheel, Kay Hofmann, David Komander	142
12	Enhanced Dendritic Cell-Induced Immune Responses Mediated by the Novel C-Type Lectin Receptor mDCAR1 2009 ·The Journal of Immunology ·(unknown), (unknown), (unknown), Kay Hofmann, Kurt S. Zaenker, Juergen Schmitz, Gregor Winkels	26
13	Involvement of the ubiquitin‐like domain of TBK1/IKK‐i kinases in regulation of IFN‐inducible genes 2007 ·The EMBO Journal ·Fumiyo Ikeda, Christina Hecker, Alexis Rozenknop, (unknown), Vladimir V. Rogov, Kay Hofmann, Shizuo Akira, Volker Dötsch, Ivan Đikić	105
14	The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis 2001 ·Current Biology ·Björn Schumacher, Kay Hofmann, Simon J. Boulton, Anton Gartner	297
15	The COP9/signalosome complex is conserved in fission yeast and has a role in S phase 1999 ·Current Biology ·Kirsten Mundt, Joanne Porte, Johanne M. Murray, Constantinos Brikos, (unknown), Thomas Caspari, Iain Hagan, Jonathan Millar, Viesturs Simanis, Kay Hofmann, Antony M. Carr	124
16	Nachweis der Tierart bei Fleisch und Fleischerzeugnissen. 2. Mitteilung 1997 ·Die Fleischwirtschaft ·Kay Hofmann	1
17	Efficient use of lactose for the lac promotercontrolled overexpression of the main antigenic protein of the foot and mouth disease virus inEscherichia coliunder fed-batch fermentation conditions 1994 ·FEMS Microbiology Reviews ·Peter Neubauer, Kay Hofmann	39
18	Interaction between photoactivated rhodopsin and its kinase: Stability and kinetics of complex formation 1993 ·Biochemistry ·Alexander Pulvermüller, K. Palczewski, Kay Hofmann	90
19	Amperometrische Titration der SH‐Gruppen in Milch mit Silbernitrat 1972 ·Food / Nahrung ·Kay Hofmann	5
20	Investigation of the inactivation of the mycotoxin patulin by sulphydryl groups. 1971 ·Die Fleischwirtschaft ·Kay Hofmann, (unknown), (unknown), L. Leistner	14

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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