William J. Rutter

64.4k total citations · 14 hit papers
311 papers, 56.7k citations indexed

About

William J. Rutter is a scholar working on Molecular Biology, Surgery and Genetics. According to data from OpenAlex, William J. Rutter has authored 311 papers receiving a total of 56.7k indexed citations (citations by other indexed papers that have themselves been cited), including 202 papers in Molecular Biology, 82 papers in Surgery and 63 papers in Genetics. Recurrent topics in William J. Rutter's work include Pancreatic function and diabetes (78 papers), RNA and protein synthesis mechanisms (35 papers) and Metabolism, Diabetes, and Cancer (26 papers). William J. Rutter is often cited by papers focused on Pancreatic function and diabetes (78 papers), RNA and protein synthesis mechanisms (35 papers) and Metabolism, Diabetes, and Cancer (26 papers). William J. Rutter collaborates with scholars based in United States, Hungary and Israel. William J. Rutter's co-authors include Raymond J. MacDonald, John M. Chirgwin, Alan Przybyla, Robert G. Roeder, Raymond Pictet, Graeme I. Bell, Richard A. Roth, Pablo Valenzuela, Michael Walker and Mark Selby and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

William J. Rutter

310 papers receiving 52.9k citations

Hit Papers

Isolation of biologically active ribonucleic acid from so... 1969 2026 1988 2007 1979 1980 1985 1977 1986 5.0k 10.0k 15.0k 20.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    1979 21.3k citations William J. Rutter et al. Biochemistry profile →
  2. Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes
    1980 1.8k citations William J. Rutter et al. Cell profile →
  3. The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
    1985 1.3k citations László Gráf, Richard A. Roth et al. Cell profile →
  4. Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences
    1977 1.1k citations William J. Rutter et al. profile →
  5. Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose
    1986 1.0k citations Richard A. Roth, William J. Rutter et al. Cell profile →
  6. Specific Inhibition of Nuclear RNA Polymerase II by α-Amanitin
    1970 762 citations Fanyela Weinberg, William J. Rutter et al. profile →
  7. Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms
    1969 757 citations William J. Rutter et al. profile →
  8. Insulin-like growth factor II receptor as a multifunctional binding protein
    1987 727 citations Jeffrey C. Edman, David N. Standring et al. profile →
  9. Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements
    1985 654 citations Helena Edlund, Michael Walker et al. profile →
  10. Synthesis and assembly of hepatitis B virus surface antigen particles in yeast
    1982 647 citations Pablo Valenzuela, William J. Rutter et al. profile →
  11. Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes
    1983 584 citations Michael Walker, Helena Edlund et al. profile →
  12. Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin
    1985 553 citations Jeffrey C. Edman, Richard A. Roth et al. profile →
  13. Sequence of the human insulin gene
    1980 418 citations William J. Rutter et al. profile →
  14. An ultrastructural analysis of the developing embryonic pancreas
    1972 400 citations William J. Rutter et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
William J. Rutter United States 101 35.4k 9.8k 8.1k 6.1k 5.9k 311 56.7k
Piotr Chomczyński United States 25 26.5k 0.7× 6.1k 0.6× 4.0k 0.5× 3.5k 0.6× 7.1k 1.2× 54 51.9k
Lelio Orci Switzerland 121 28.7k 0.8× 6.7k 0.7× 16.1k 2.0× 8.1k 1.3× 2.2k 0.4× 582 52.4k
Oliver Smithies United States 97 26.5k 0.7× 11.4k 1.2× 2.8k 0.3× 5.5k 0.9× 6.0k 1.0× 331 55.5k
Nicoletta Sacchi Italy 34 26.0k 0.7× 6.0k 0.6× 3.8k 0.5× 3.0k 0.5× 7.6k 1.3× 150 50.8k
Jun‐ichi Miyazaki Japan 85 19.4k 0.5× 7.2k 0.7× 7.4k 0.9× 3.3k 0.5× 5.8k 1.0× 498 36.0k
Harvey F. Lodish United States 150 49.1k 1.4× 6.7k 0.7× 6.2k 0.8× 3.0k 0.5× 8.7k 1.5× 646 82.0k
Bert W. O’Malley United States 139 40.6k 1.1× 35.6k 3.6× 6.3k 0.8× 9.9k 1.6× 9.6k 1.6× 964 77.9k
T. Staehelin Switzerland 22 28.0k 0.8× 5.6k 0.6× 2.2k 0.3× 1.4k 0.2× 6.6k 1.1× 27 52.5k
J. Gordon United Kingdom 23 27.6k 0.8× 5.8k 0.6× 2.2k 0.3× 1.4k 0.2× 6.4k 1.1× 56 52.1k
David E. Housman United States 104 32.2k 0.9× 9.2k 0.9× 3.0k 0.4× 2.1k 0.3× 3.0k 0.5× 329 47.8k

Countries citing papers authored by William J. Rutter

Since Specialization
Citations

This map shows the geographic impact of William J. Rutter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William J. Rutter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William J. Rutter more than expected).

Fields of papers citing papers by William J. Rutter

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William J. Rutter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William J. Rutter. The network helps show where William J. Rutter may publish in the future.

Co-authorship network of co-authors of William J. Rutter

This figure shows the co-authorship network connecting the top 25 collaborators of William J. Rutter. A scholar is included among the top collaborators of William J. Rutter based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William J. Rutter. William J. Rutter is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Venekei, István, Lizbeth Hedstrom, & William J. Rutter. (1996). A rapid and effective procedure for screening protease mutants. Protein Engineering Design and Selection. 9(1). 85–93. 10 indexed citations
3.
Kennedy, Giulia C., Michael S. German, & William J. Rutter. (1995). The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. Nature Genetics. 9(3). 293–298. 307 indexed citations
4.
Vierra, Craig, et al.. (1994). Purification of E. coli -Synthesized Pan Proteins and Development of a Pan-Specific Monoclonal Antibody. Hybridoma. 13(3). 191–197. 3 indexed citations
5.
Johnson, J. David, Jeffrey C. Edman, & William J. Rutter. (1993). A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain.. Proceedings of the National Academy of Sciences. 90(12). 5677–5681. 149 indexed citations
6.
Gittes, George K., William J. Rutter, & Haile T. Debas. (1993). Initiation of gastrin expression during the development of the mouse pancreas. The American Journal of Surgery. 165(1). 23–26. 11 indexed citations
7.
Schellenberger, Volker, Christoph W. Turck, Lizbeth Hedstrom, & William J. Rutter. (1993). Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles. Biochemistry. 32(16). 4349–4353. 77 indexed citations
8.
Phillips, Margaret A., Lizbeth Hedstrom, & William J. Rutter. (1992). Guanidine derivatives restore activity to carboxypeptidase lacking arginine‐127. Protein Science. 1(4). 517–521. 28 indexed citations
9.
Weinrich, Scott L., Andreas Meister, & William J. Rutter. (1991). Exocrine Pancreas Transcription Factor 1 Binds to a Bipartite Enhancer Element and Activates Transcription of Acinar Genes. Molecular and Cellular Biology. 11(10). 4985–4997. 14 indexed citations
10.
Pierce, Sarah B., et al.. (1991). Endogenous Substrates of the Insulin Receptor: Studies with Cells Expressing Wild-Type and Mutant Receptors. Advances in experimental medicine and biology. 293. 227–238. 7 indexed citations
11.
Karlsson, Olof, Michael Walker, William J. Rutter, & Helena Edlund. (1989). Individual Protein-Binding Domains of the Insulin Gene Enhancer Positively Activate β-Cell-Specific Transcription. Molecular and Cellular Biology. 9(2). 823–827. 23 indexed citations
12.
Edwards, Robert H., William J. Rutter, & Douglas Hanahan. (1989). Directed expression of NGF to pancreatic β cells in transgenic mice leads to selective hyperinnervation of the islets. Cell. 58(1). 161–170. 141 indexed citations
13.
Kaplan, G, Dennis J. Pillion, William J. Rutter, Helen Kim, & Peter E. Barker. (1989). Insulin receptor overexpression in a human pre-B acute lymphocytic leukemia cell line with a t(1;19) chromosome translocation near the INSR locus. Biochemical and Biophysical Research Communications. 159(3). 1275–1282. 6 indexed citations
14.
Nir, Uri, Eric Fodor, & William J. Rutter. (1988). Capturing Nuclear Sequence-Specific DNA-Binding Proteins by Using Simian Virus 40-Derived Minichromosomes. Molecular and Cellular Biology. 8(2). 982–987. 6 indexed citations
15.
Edwards, Robert H., Mark Selby, William C. Mobley, et al.. (1988). Processing and Secretion of Nerve Growth Factor: Expression in Mammalian Cells with a Vaccinia Virus Vector. Molecular and Cellular Biology. 8(6). 2456–2464. 29 indexed citations
16.
Raimondi, Elena, et al.. (1988). Regional mapping of the human placental alkaline phosphatase gene (ALPP) to 2q37 by in situ hybridization. Cytogenetic and Genome Research. 47(1-2). 98–99. 16 indexed citations
17.
Han, Jang H. & William J. Rutter. (1988). λgt22S, a phage expression vector for the directional cloning of cDNA by the use of a single restriction enzyme SfiI. Nucleic Acids Research. 16(24). 11837–11837. 7 indexed citations
18.
Sprang, Stephen R., Robert J. Fletterick, László Gráf, William J. Rutter, & Charles S. Craik. (1988). Studies of Specificity and Catalysis in Trypsin by Structural Analysis of Site-Directed Mutants. Critical Reviews in Biotechnology. 8(3). 225–236. 18 indexed citations
19.
Standring, David N., Leslie B. Rall, Orgad Laub, & William J. Rutter. (1983). Hepatitis B Virus Encodes an RNA Polymerase III Transcript. Molecular and Cellular Biology. 3(10). 1774–1782. 12 indexed citations
20.
Hager, Gordon L., Michael J. Holland, Pablo Valenzuela, Fanyela Weinberg, & William J. Rutter. (1976). RNA Polymerases and Transcriptive Specificity in Saccharomyces cerevisiae. Cold Spring Harbor Monograph Archive. 6. 745–762. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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